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The map label for this gene is trpS [H]

Identifier: 189183071

GI number: 189183071

Start: 158057

End: 159064

Strand: Direct

Name: trpS [H]

Synonym: OTT_0164

Alternate gene names: 189183071

Gene position: 158057-159064 (Clockwise)

Preceding gene: 189183070

Following gene: 189183075

Centisome position: 7.87

GC content: 29.86

Gene sequence:

>1008_bases
ATGTCCAAACGTATATTATCTGGTATACAGGTTACAGGAAAGCAGCATCTTGGCAATTATTTAGGATCTATACAGAAATG
GGTTCAAATGCAATCAAAATTTCAGTCCATATTTTTTCTTGCTAATCTACATTCAATTACTACTTCGCAAGAATCATTGA
AACTAAGTGAGTCGATATTTAGTTCAGCTTGCATGCTTCTAGCATGCGGAATAAATCCTAAACAATCAATAATTTTTCTT
CAATCTGATGTTAAAGAACACTCAGAGCTTGCATGGATACTAAATTGCGTTACTCCACTTGGTCAATTAAAACGAATGAC
TCAATTTAAAGATAAAGCTACCAAATGTAGCTCAAATAATATCAACTTAGGGTTGTTAGCATATCCTGTACTGATGGCTG
CAGATGTTCTGTTATATCAAGCAGATTTAGTACCAGTCGGGGCTGATCAAAAGCAACATTTAGAACTAGTAAGAGATATA
GTTAAAATAATCCATCATAAGTTTAATGATGATACCATTTTCAAGTTACCGGAACTATTTATAGATCATACAGCAGGAAA
AATCATGAGTCTAAAAGATGGCAGAAAAAAAATGAGTAAGTCTGATATCTCTGATTTTAGTAGAATTAATCTAACTGATT
CACAAGATATTATTTTCAGAAAGTTGCAAAAAGCAAAAACTGATTGCTATACTCAAATCACATATGATCCTACAGGCAGA
CCAGAGATTTCTAATCTAATTAATATATTTGCTGCACTATCTAATAAAACCACTAATGATATAGTAAAAGAATATGAATA
TGCAGAATTAACTAAATTTAAAAAAGACTTAGCAATGTTAATTATTGATTGTCTTAACCCTATTTTGAAAGAATATAATA
ATTATATGAATAATTTAGATTATGTTAATCAAGTATTAATTACAGGGGCTAATCAGGCTAAAATAATAGCTGAAAAAACC
ATAACAAAAGTAAAACAAAAATTTGGACTACAAATTTTGTCAACATAA

Upstream 100 bases:

>100_bases
TTAATACTTCAAAATTAGAATTTAAAAAATTATTAATGCTAAAAACTTCAAATATGTTTATAATAAACACCATTTAAAAC
ATTTAAAGTCAGGTATATTA

Downstream 100 bases:

>100_bases
ATATGATATCTAAATCTAAAACTAAATATGCTTTACATCGAGCTATTAAAGATGCGATATTGAAAAAGTACAGCAAGGAT
AGCACACTTTGTAAATTCAA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSKRILSGIQVTGKQHLGNYLGSIQKWVQMQSKFQSIFFLANLHSITTSQESLKLSESIFSSACMLLACGINPKQSIIFL
QSDVKEHSELAWILNCVTPLGQLKRMTQFKDKATKCSSNNINLGLLAYPVLMAADVLLYQADLVPVGADQKQHLELVRDI
VKIIHHKFNDDTIFKLPELFIDHTAGKIMSLKDGRKKMSKSDISDFSRINLTDSQDIIFRKLQKAKTDCYTQITYDPTGR
PEISNLINIFAALSNKTTNDIVKEYEYAELTKFKKDLAMLIIDCLNPILKEYNNYMNNLDYVNQVLITGANQAKIIAEKT
ITKVKQKFGLQILST

Sequences:

>Translated_335_residues
MSKRILSGIQVTGKQHLGNYLGSIQKWVQMQSKFQSIFFLANLHSITTSQESLKLSESIFSSACMLLACGINPKQSIIFL
QSDVKEHSELAWILNCVTPLGQLKRMTQFKDKATKCSSNNINLGLLAYPVLMAADVLLYQADLVPVGADQKQHLELVRDI
VKIIHHKFNDDTIFKLPELFIDHTAGKIMSLKDGRKKMSKSDISDFSRINLTDSQDIIFRKLQKAKTDCYTQITYDPTGR
PEISNLINIFAALSNKTTNDIVKEYEYAELTKFKKDLAMLIIDCLNPILKEYNNYMNNLDYVNQVLITGANQAKIIAEKT
ITKVKQKFGLQILST
>Mature_334_residues
SKRILSGIQVTGKQHLGNYLGSIQKWVQMQSKFQSIFFLANLHSITTSQESLKLSESIFSSACMLLACGINPKQSIIFLQ
SDVKEHSELAWILNCVTPLGQLKRMTQFKDKATKCSSNNINLGLLAYPVLMAADVLLYQADLVPVGADQKQHLELVRDIV
KIIHHKFNDDTIFKLPELFIDHTAGKIMSLKDGRKKMSKSDISDFSRINLTDSQDIIFRKLQKAKTDCYTQITYDPTGRP
EISNLINIFAALSNKTTNDIVKEYEYAELTKFKKDLAMLIIDCLNPILKEYNNYMNNLDYVNQVLITGANQAKIIAEKTI
TKVKQKFGLQILST

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=329, Percent_Identity=40.1215805471125, Blast_Score=259, Evalue=2e-69,
Organism=Homo sapiens, GI41352700, Length=177, Percent_Identity=48.5875706214689, Blast_Score=178, Evalue=6e-45,
Organism=Escherichia coli, GI1789786, Length=328, Percent_Identity=39.0243902439024, Blast_Score=257, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI71982800, Length=330, Percent_Identity=32.7272727272727, Blast_Score=201, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71982793, Length=330, Percent_Identity=32.7272727272727, Blast_Score=200, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320474, Length=348, Percent_Identity=35.632183908046, Blast_Score=198, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24666151, Length=329, Percent_Identity=39.209726443769, Blast_Score=253, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37922; Mature: 37790

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRILSGIQVTGKQHLGNYLGSIQKWVQMQSKFQSIFFLANLHSITTSQESLKLSESIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SSACMLLACGINPKQSIIFLQSDVKEHSELAWILNCVTPLGQLKRMTQFKDKATKCSSNN
HHHHHHHHCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
INLGLLAYPVLMAADVLLYQADLVPVGADQKQHLELVRDIVKIIHHKFNDDTIFKLPELF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IDHTAGKIMSLKDGRKKMSKSDISDFSRINLTDSQDIIFRKLQKAKTDCYTQITYDPTGR
HHHCCCHHEECHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCC
PEISNLINIFAALSNKTTNDIVKEYEYAELTKFKKDLAMLIIDCLNPILKEYNNYMNNLD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVNQVLITGANQAKIIAEKTITKVKQKFGLQILST
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEECCC
>Mature Secondary Structure 
SKRILSGIQVTGKQHLGNYLGSIQKWVQMQSKFQSIFFLANLHSITTSQESLKLSESIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SSACMLLACGINPKQSIIFLQSDVKEHSELAWILNCVTPLGQLKRMTQFKDKATKCSSNN
HHHHHHHHCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
INLGLLAYPVLMAADVLLYQADLVPVGADQKQHLELVRDIVKIIHHKFNDDTIFKLPELF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IDHTAGKIMSLKDGRKKMSKSDISDFSRINLTDSQDIIFRKLQKAKTDCYTQITYDPTGR
HHHCCCHHEECHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCC
PEISNLINIFAALSNKTTNDIVKEYEYAELTKFKKDLAMLIIDCLNPILKEYNNYMNNLD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVNQVLITGANQAKIIAEKTITKVKQKFGLQILST
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]