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The map label for this gene is cox11 [H]

Identifier: 189182924

GI number: 189182924

Start: 21205

End: 21732

Strand: Reverse

Name: cox11 [H]

Synonym: OTT_0017

Alternate gene names: 189182924

Gene position: 21732-21205 (Counterclockwise)

Preceding gene: 189182940

Following gene: 189182922

Centisome position: 1.08

GC content: 27.08

Gene sequence:

>528_bases
GTGAAAGCAAAAAATAATGAAATAATATTTACTTTAATATCACTGATAGTTAGTATGCTAATTTTAAGCTTTGCTTCAGT
ACCAATCTATAGTTTGTTTTGTAAAGTCACAGGGTTTGGAGGTACAGTACGACAGCAAATTGCAAGCTCTAAAAAAAAAG
GTAAGAAACAAATAACTATAAACTTTGACGCAAATATTGAACAAAATTTACAATGGCAATTTATTCCAAAACAAAAAAGT
ATTACCGTTACTACTGGTGAAAATAATTTAGTATTTTATTATTCACGTAATCTAACAAACCGTGATATAGTCGGAACTGC
AATTTATAATGTGACTCCAAATAAAGCAGGGAAATATTTTGTCAAAATTTATTGTTTTTGTTTTGAGGAACAATTATTAA
AAAAACAAGAAGAAATCTTAATGCCAGTATCATTTTATATAGATCCAGCTATAGAAGATGATCCATATATGAATGATGTT
AATACTATTACTCTATCATATACTTTTTTTAAGATAAGAGAGCAATAG

Upstream 100 bases:

>100_bases
ATAAAATTTTATATATTACAAATGAGACAATGAACATTAATAGTAAGTTCACTATATCTTCTATGTTTAAGAAAAAATTA
TTTTTTCTTCATTAATAGCC

Downstream 100 bases:

>100_bases
ATTTTTTTTTGAAACTTAAAAATCAATAGACCTTCTGTAAAATACCAAAACTAATTAGAATTATGATTTAATAAGAGAAG
AATAAGTATGGTAGATAATC

Product: cytochrome C oxidase assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MKAKNNEIIFTLISLIVSMLILSFASVPIYSLFCKVTGFGGTVRQQIASSKKKGKKQITINFDANIEQNLQWQFIPKQKS
ITVTTGENNLVFYYSRNLTNRDIVGTAIYNVTPNKAGKYFVKIYCFCFEEQLLKKQEEILMPVSFYIDPAIEDDPYMNDV
NTITLSYTFFKIREQ

Sequences:

>Translated_175_residues
MKAKNNEIIFTLISLIVSMLILSFASVPIYSLFCKVTGFGGTVRQQIASSKKKGKKQITINFDANIEQNLQWQFIPKQKS
ITVTTGENNLVFYYSRNLTNRDIVGTAIYNVTPNKAGKYFVKIYCFCFEEQLLKKQEEILMPVSFYIDPAIEDDPYMNDV
NTITLSYTFFKIREQ
>Mature_175_residues
MKAKNNEIIFTLISLIVSMLILSFASVPIYSLFCKVTGFGGTVRQQIASSKKKGKKQITINFDANIEQNLQWQFIPKQKS
ITVTTGENNLVFYYSRNLTNRDIVGTAIYNVTPNKAGKYFVKIYCFCFEEQLLKKQEEILMPVSFYIDPAIEDDPYMNDV
NTITLSYTFFKIREQ

Specific function: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I [H]

COG id: COG3175

COG function: function code O; Cytochrome oxidase assembly factor

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX11/CtaG family [H]

Homologues:

Organism=Homo sapiens, GI4758034, Length=179, Percent_Identity=44.6927374301676, Blast_Score=166, Evalue=1e-41,
Organism=Homo sapiens, GI242247061, Length=128, Percent_Identity=37.5, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI242247057, Length=128, Percent_Identity=37.5, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71990692, Length=176, Percent_Identity=39.2045454545455, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6325125, Length=176, Percent_Identity=42.6136363636364, Blast_Score=155, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24581944, Length=178, Percent_Identity=43.8202247191011, Blast_Score=159, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007533 [H]

Pfam domain/function: PF04442 CtaG_Cox11 [H]

EC number: NA

Molecular weight: Translated: 20177; Mature: 20177

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKNNEIIFTLISLIVSMLILSFASVPIYSLFCKVTGFGGTVRQQIASSKKKGKKQITI
CCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHEEEEECCCHHHHHHHHHHHHCCCEEEEE
NFDANIEQNLQWQFIPKQKSITVTTGENNLVFYYSRNLTNRDIVGTAIYNVTPNKAGKYF
EECCCCCCCCEEEEECCCCEEEEEECCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCEE
VKIYCFCFEEQLLKKQEEILMPVSFYIDPAIEDDPYMNDVNTITLSYTFFKIREQ
EEEEEEHHHHHHHCCHHHHCCEEEEEECCCCCCCCCCCCCEEEEEEEEEEEEECC
>Mature Secondary Structure
MKAKNNEIIFTLISLIVSMLILSFASVPIYSLFCKVTGFGGTVRQQIASSKKKGKKQITI
CCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHEEEEECCCHHHHHHHHHHHHCCCEEEEE
NFDANIEQNLQWQFIPKQKSITVTTGENNLVFYYSRNLTNRDIVGTAIYNVTPNKAGKYF
EECCCCCCCCEEEEECCCCEEEEEECCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCEE
VKIYCFCFEEQLLKKQEEILMPVSFYIDPAIEDDPYMNDVNTITLSYTFFKIREQ
EEEEEEHHHHHHHCCHHHHCCEEEEEECCCCCCCCCCCCCEEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]