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The map label for this gene is clpX [H]

Identifier: 189182914

GI number: 189182914

Start: 11872

End: 13125

Strand: Reverse

Name: clpX [H]

Synonym: OTT_0007

Alternate gene names: 189182914

Gene position: 13125-11872 (Counterclockwise)

Preceding gene: 189182922

Following gene: 189182909

Centisome position: 0.65

GC content: 32.14

Gene sequence:

>1254_bases
ATGGCTAAAAAAATTGACAATAAAGCATTGTCCTGTTCGTTTTGTTGTAAAAATCAAAATGAAGTTAAAAAATTAATAGC
TGGCTTTTCAGGCTTTATTTGCGATGAATGCATTGAGCTATGTATTCATCTAATTGAGGAAGAGCGTAAATCTAATTTAG
CTATATCTAACTATTCAAAATTGCCACCAAAAAAAATATATGAAGCAATTAATGCTCATGTTGTAGGGCAGCAGCAGGCT
GCTAAAATTCTAGCTGTAGCTGTTTATATTCAGTGTATAAGGTTTGAGCATCGAGAATTAGCTGATCTTGTAGCAAAATC
TAATGTGTTACTTATTGGACCTACTGGTTGCGGTAAGACTTTAATAGCACAAACTTTAGCAAAAATAATTAATGTGCCAT
TTGCAATGGCTGATGCTACTTCGTTAACTGAAGCTGGCTATGTAGGAGAGGATGTTGAGAACATTATTCTAAGACTATTA
CAAGCAGCAGATTTTAATGTTGAAAGAGCCCAAAAAGGAATCATATATATTGATGAAATAGATAAAATTGCTCGTAAGTC
AGAAAACCCTTCTATTACAAGAGATGTATCTGGTGAAGGAGTACAGCAAGCTTTATTAAAAATTATGGAAGGAACTATTG
CATTAGTGCCTCCTCAAGGAGGAAGAAAACATCCTCAGCAAGAATTTATTCAAATAGATACAACTAATATGTTATTCATA
TGCGGCGGTGCTTTTACTGGAATTGAAAAGATTATTGAAGCCAGGACTTCACAAAGTACTATAGGATTTGAAGCAACAGT
GAAATCAAAACATGATCAAGATTATAATCAAATTCTGAATAATCTTGAAGCTGATGATTTAACTAAATTTGGATTAATTC
CTGAATTTTTGGGTAGATTACCTGTAATTGCGACATTATCTGATCTAAATCAACAGTCTTTAGTAGATATATTAACAAAA
CCTAAAAATGCTTTAGTTAAGCAATATCAAAAACTTTTTGAACTTGATGGAGCAGAATTGATTTTTGAAGAAGAAGCGCT
AGTAGCAATTGCTCAAAAGGCGTTAGCAAAAAAAACTGGCGCTAGAGGGTTACGTGCAATTTTAGAATGCGTATTATTAG
ATACAATGTTTGAGTTAAGTAATCTTAAAAATATGCAAGTAATAATCACAGCTGATATTGTCAAAAATAATCTAAAGCCT
ATTATAAAGCCTAAACTGCAAAAAAAATCAGCGAAAAAAAAAGTTACAGCTTAA

Upstream 100 bases:

>100_bases
CTTGAAAATTATGATTTATATATATATAGTAATCAAAAGGTAGTTTATTAAAAATCAAAATATAAGACCACTATAAATTT
CTAAATAACAATATTAAGTT

Downstream 100 bases:

>100_bases
ACAAATCAGTGCAATTTAGTTAAGACAATTTCTTTTTTATGATTTTGACAAAGTAAGAAGCAAGCTTTTTAAGATATAGC
TTTTAATAAAGCCGAATTAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MAKKIDNKALSCSFCCKNQNEVKKLIAGFSGFICDECIELCIHLIEEERKSNLAISNYSKLPPKKIYEAINAHVVGQQQA
AKILAVAVYIQCIRFEHRELADLVAKSNVLLIGPTGCGKTLIAQTLAKIINVPFAMADATSLTEAGYVGEDVENIILRLL
QAADFNVERAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKIMEGTIALVPPQGGRKHPQQEFIQIDTTNMLFI
CGGAFTGIEKIIEARTSQSTIGFEATVKSKHDQDYNQILNNLEADDLTKFGLIPEFLGRLPVIATLSDLNQQSLVDILTK
PKNALVKQYQKLFELDGAELIFEEEALVAIAQKALAKKTGARGLRAILECVLLDTMFELSNLKNMQVIITADIVKNNLKP
IIKPKLQKKSAKKKVTA

Sequences:

>Translated_417_residues
MAKKIDNKALSCSFCCKNQNEVKKLIAGFSGFICDECIELCIHLIEEERKSNLAISNYSKLPPKKIYEAINAHVVGQQQA
AKILAVAVYIQCIRFEHRELADLVAKSNVLLIGPTGCGKTLIAQTLAKIINVPFAMADATSLTEAGYVGEDVENIILRLL
QAADFNVERAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKIMEGTIALVPPQGGRKHPQQEFIQIDTTNMLFI
CGGAFTGIEKIIEARTSQSTIGFEATVKSKHDQDYNQILNNLEADDLTKFGLIPEFLGRLPVIATLSDLNQQSLVDILTK
PKNALVKQYQKLFELDGAELIFEEEALVAIAQKALAKKTGARGLRAILECVLLDTMFELSNLKNMQVIITADIVKNNLKP
IIKPKLQKKSAKKKVTA
>Mature_416_residues
AKKIDNKALSCSFCCKNQNEVKKLIAGFSGFICDECIELCIHLIEEERKSNLAISNYSKLPPKKIYEAINAHVVGQQQAA
KILAVAVYIQCIRFEHRELADLVAKSNVLLIGPTGCGKTLIAQTLAKIINVPFAMADATSLTEAGYVGEDVENIILRLLQ
AADFNVERAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKIMEGTIALVPPQGGRKHPQQEFIQIDTTNMLFIC
GGAFTGIEKIIEARTSQSTIGFEATVKSKHDQDYNQILNNLEADDLTKFGLIPEFLGRLPVIATLSDLNQQSLVDILTKP
KNALVKQYQKLFELDGAELIFEEEALVAIAQKALAKKTGARGLRAILECVLLDTMFELSNLKNMQVIITADIVKNNLKPI
IKPKLQKKSAKKKVTA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=319, Percent_Identity=48.58934169279, Blast_Score=297, Evalue=1e-80,
Organism=Escherichia coli, GI1786642, Length=415, Percent_Identity=58.0722891566265, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=42.4528301886792, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=44.5512820512821, Blast_Score=260, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI71982905, Length=297, Percent_Identity=45.7912457912458, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71988663, Length=392, Percent_Identity=36.2244897959184, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=38.1526104417671, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6319704, Length=415, Percent_Identity=36.8674698795181, Blast_Score=232, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24648291, Length=312, Percent_Identity=48.0769230769231, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24648289, Length=312, Percent_Identity=48.0769230769231, Blast_Score=291, Evalue=5e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 45948; Mature: 45817

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKIDNKALSCSFCCKNQNEVKKLIAGFSGFICDECIELCIHLIEEERKSNLAISNYSK
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCC
LPPKKIYEAINAHVVGQQQAAKILAVAVYIQCIRFEHRELADLVAKSNVLLIGPTGCGKT
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHH
LIAQTLAKIINVPFAMADATSLTEAGYVGEDVENIILRLLQAADFNVERAQKGIIYIDEI
HHHHHHHHHHCCCHHHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEEHHH
DKIARKSENPSITRDVSGEGVQQALLKIMEGTIALVPPQGGRKHPQQEFIQIDTTNMLFI
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHEEECCCCEEEE
CGGAFTGIEKIIEARTSQSTIGFEATVKSKHDQDYNQILNNLEADDLTKFGLIPEFLGRL
ECCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHCCHHHHHCCC
PVIATLSDLNQQSLVDILTKPKNALVKQYQKLFELDGAELIFEEEALVAIAQKALAKKTG
CHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHC
ARGLRAILECVLLDTMFELSNLKNMQVIITADIVKNNLKPIIKPKLQKKSAKKKVTA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
AKKIDNKALSCSFCCKNQNEVKKLIAGFSGFICDECIELCIHLIEEERKSNLAISNYSK
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCC
LPPKKIYEAINAHVVGQQQAAKILAVAVYIQCIRFEHRELADLVAKSNVLLIGPTGCGKT
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHH
LIAQTLAKIINVPFAMADATSLTEAGYVGEDVENIILRLLQAADFNVERAQKGIIYIDEI
HHHHHHHHHHCCCHHHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEEHHH
DKIARKSENPSITRDVSGEGVQQALLKIMEGTIALVPPQGGRKHPQQEFIQIDTTNMLFI
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHEEECCCCEEEE
CGGAFTGIEKIIEARTSQSTIGFEATVKSKHDQDYNQILNNLEADDLTKFGLIPEFLGRL
ECCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHCCCHHHHHHHCCHHHHHCCC
PVIATLSDLNQQSLVDILTKPKNALVKQYQKLFELDGAELIFEEEALVAIAQKALAKKTG
CHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHC
ARGLRAILECVLLDTMFELSNLKNMQVIITADIVKNNLKPIIKPKLQKKSAKKKVTA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA