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The map label for this gene is lolC [H]

Identifier: 189025807

GI number: 189025807

Start: 631754

End: 633043

Strand: Direct

Name: lolC [H]

Synonym: TPASS_0580

Alternate gene names: 189025807

Gene position: 631754-633043 (Clockwise)

Preceding gene: 189025806

Following gene: 189025808

Centisome position: 55.44

GC content: 46.9

Gene sequence:

>1290_bases
ATGAGTAACACCCACGTGCAAACGCTGCGGTGGATGTGTTTTATGGTGCGCAGATTAAATTCAGTGCGCGCGCGGAGTGC
GAACGCGATTACCAGTCTTTTTTTTATATTAGGCATTGCCTTTGGGGCACTTACCTTAATTGTCATCCTTTCGGTTATGA
ACGGCTTCCAGCAGGGTTTTATTGGCACCATTTTACAGGTGAGTTCTGCACACGTTCGTGTATATGGCAGTGTTGACGCA
GTAAAACGTGCAGAGACGTTAGGCGGCTATCAATCCTTTTATCCATTTATAGAAGCGCATGCCTTATTGCAAGGCAACTA
TTATCGGCAACACGGTGCGCTTGTGCGTGCAGTTCCTGCAGATATCTTCCATCGGGATAGGTTGCTGGCGCGTGCACTCC
CGATAACATCCGGAAGTTTTAATTTGAGTAAAAAGCACTCCATTGTGCTCGGATATGAACTGGCGCGCCACCTTTCGGTA
CGTACCGGAGATCAGGTTGACACGCTTGCCCTGTCAGGAAGTGATACACAAAAGATAATGCCAGGCTGGAATAAACTTAC
GGTAACGGGCATTTTCAAATCGGGATACCACGAAGTAGATTCCACGTTTGCGTACATTCCTCTGGACATGGGCACCACTT
TATTTGGTACGACGCCTGATATTACCGCGGCAGTCAAACTAAATAACCATGAGCGAGACGATCGCTACCTTTTCTTTCTT
GCACAACACATTCCTGATCTCAAGGCAGAATCCTGGCGGGAGTACAACCGTGCTTTTTTTAGTGCGCTCCGCATAGAGAA
GAACGTCATGATACTTCTTGTCATTTTGATTTTTATGGTGGTAACCGTAAACATTTATCACAGCATGCGCCGCTCTATTC
GCACTCGAAAGGAAGAAATTGCTATGCTCGTTTCACTTGGCGCCCCTGTCAGTCACGTGCAGATTCTGTTCATCGGCAAT
GGCATTATGATTGGCTTTTTGGGCTCTCTCTTGGGGGTACTCCTGGGATTGCTCATTACTATCCACGTTAACGAAATAAT
TGCGTGCATTGAGACTGCTGTAAATTCTGCGTTTTTCCTGTTCTCCCTCTTCTCGGGAACGAAAACCCCTTCTTTCAGTG
TGTTTGGTACGCAATATTTTTACAACGTGGAGCGTATTCCCGTGCAGATTTTCTTTCAGGAGGTACTGTTTGTATTTCTG
TTTGGCACAGGTTCTGCGTCTGTTGCAACGTACCTTGCCACGCGTAAAATACTCCTGCTCAAGCCGGCTGAGGTGCTACG
CGATGAATGA

Upstream 100 bases:

>100_bases
AACGGCGTATTACAGGCAATAATTCACCAAAAGGAAGGTGCGCAGGACGTGCAGGTATTTGAGCGTGGGAAGGAAATTTA
CTCTACAAAGGAAGTACACG

Downstream 100 bases:

>100_bases
CCCAATTCTTTCTGTCGAACAAGTAAGTAAAAGCTTCTGCTGCGCAACAGAACGTATACAGATTTTGTCTGACGTATCAT
TTAGCGTGCCGCGTGCAGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSNTHVQTLRWMCFMVRRLNSVRARSANAITSLFFILGIAFGALTLIVILSVMNGFQQGFIGTILQVSSAHVRVYGSVDA
VKRAETLGGYQSFYPFIEAHALLQGNYYRQHGALVRAVPADIFHRDRLLARALPITSGSFNLSKKHSIVLGYELARHLSV
RTGDQVDTLALSGSDTQKIMPGWNKLTVTGIFKSGYHEVDSTFAYIPLDMGTTLFGTTPDITAAVKLNNHERDDRYLFFL
AQHIPDLKAESWREYNRAFFSALRIEKNVMILLVILIFMVVTVNIYHSMRRSIRTRKEEIAMLVSLGAPVSHVQILFIGN
GIMIGFLGSLLGVLLGLLITIHVNEIIACIETAVNSAFFLFSLFSGTKTPSFSVFGTQYFYNVERIPVQIFFQEVLFVFL
FGTGSASVATYLATRKILLLKPAEVLRDE

Sequences:

>Translated_429_residues
MSNTHVQTLRWMCFMVRRLNSVRARSANAITSLFFILGIAFGALTLIVILSVMNGFQQGFIGTILQVSSAHVRVYGSVDA
VKRAETLGGYQSFYPFIEAHALLQGNYYRQHGALVRAVPADIFHRDRLLARALPITSGSFNLSKKHSIVLGYELARHLSV
RTGDQVDTLALSGSDTQKIMPGWNKLTVTGIFKSGYHEVDSTFAYIPLDMGTTLFGTTPDITAAVKLNNHERDDRYLFFL
AQHIPDLKAESWREYNRAFFSALRIEKNVMILLVILIFMVVTVNIYHSMRRSIRTRKEEIAMLVSLGAPVSHVQILFIGN
GIMIGFLGSLLGVLLGLLITIHVNEIIACIETAVNSAFFLFSLFSGTKTPSFSVFGTQYFYNVERIPVQIFFQEVLFVFL
FGTGSASVATYLATRKILLLKPAEVLRDE
>Mature_428_residues
SNTHVQTLRWMCFMVRRLNSVRARSANAITSLFFILGIAFGALTLIVILSVMNGFQQGFIGTILQVSSAHVRVYGSVDAV
KRAETLGGYQSFYPFIEAHALLQGNYYRQHGALVRAVPADIFHRDRLLARALPITSGSFNLSKKHSIVLGYELARHLSVR
TGDQVDTLALSGSDTQKIMPGWNKLTVTGIFKSGYHEVDSTFAYIPLDMGTTLFGTTPDITAAVKLNNHERDDRYLFFLA
QHIPDLKAESWREYNRAFFSALRIEKNVMILLVILIFMVVTVNIYHSMRRSIRTRKEEIAMLVSLGAPVSHVQILFIGNG
IMIGFLGSLLGVLLGLLITIHVNEIIACIETAVNSAFFLFSLFSGTKTPSFSVFGTQYFYNVERIPVQIFFQEVLFVFLF
GTGSASVATYLATRKILLLKPAEVLRDE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=431, Percent_Identity=23.8979118329466, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787360, Length=320, Percent_Identity=26.875, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 47956; Mature: 47825

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTHVQTLRWMCFMVRRLNSVRARSANAITSLFFILGIAFGALTLIVILSVMNGFQQGF
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGTILQVSSAHVRVYGSVDAVKRAETLGGYQSFYPFIEAHALLQGNYYRQHGALVRAVPA
HHHHHHCCCCEEEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEHHCCCEEEECCH
DIFHRDRLLARALPITSGSFNLSKKHSIVLGYELARHLSVRTGDQVDTLALSGSDTQKIM
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEEECCCCCHHHC
PGWNKLTVTGIFKSGYHEVDSTFAYIPLDMGTTLFGTTPDITAAVKLNNHERDDRYLFFL
CCCCEEEEEEEECCCCHHHCCCEEEEEECCCCEEECCCCCCEEEEEECCCCCCCCEEEEE
AQHIPDLKAESWREYNRAFFSALRIEKNVMILLVILIFMVVTVNIYHSMRRSIRTRKEEI
HHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLVSLGAPVSHVQILFIGNGIMIGFLGSLLGVLLGLLITIHVNEIIACIETAVNSAFFL
HHHHHCCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSLFSGTKTPSFSVFGTQYFYNVERIPVQIFFQEVLFVFLFGTGSASVATYLATRKILLL
HHHHCCCCCCCEEEEEHHHEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCEEEEE
KPAEVLRDE
CCHHHHCCC
>Mature Secondary Structure 
SNTHVQTLRWMCFMVRRLNSVRARSANAITSLFFILGIAFGALTLIVILSVMNGFQQGF
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGTILQVSSAHVRVYGSVDAVKRAETLGGYQSFYPFIEAHALLQGNYYRQHGALVRAVPA
HHHHHHCCCCEEEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEHHCCCEEEECCH
DIFHRDRLLARALPITSGSFNLSKKHSIVLGYELARHLSVRTGDQVDTLALSGSDTQKIM
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEEECCCCCHHHC
PGWNKLTVTGIFKSGYHEVDSTFAYIPLDMGTTLFGTTPDITAAVKLNNHERDDRYLFFL
CCCCEEEEEEEECCCCHHHCCCEEEEEECCCCEEECCCCCCEEEEEECCCCCCCCEEEEE
AQHIPDLKAESWREYNRAFFSALRIEKNVMILLVILIFMVVTVNIYHSMRRSIRTRKEEI
HHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLVSLGAPVSHVQILFIGNGIMIGFLGSLLGVLLGLLITIHVNEIIACIETAVNSAFFL
HHHHHCCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSLFSGTKTPSFSVFGTQYFYNVERIPVQIFFQEVLFVFLFGTGSASVATYLATRKILLL
HHHHCCCCCCCEEEEEHHHEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCEEEEE
KPAEVLRDE
CCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]