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The map label for this gene is era

Identifier: 189025769

GI number: 189025769

Start: 583621

End: 584580

Strand: Direct

Name: era

Synonym: TPASS_0541

Alternate gene names: 189025769

Gene position: 583621-584580 (Clockwise)

Preceding gene: 189025768

Following gene: 189025776

Centisome position: 51.22

GC content: 55.1

Gene sequence:

>960_bases
ATGGTAACGGACGGCGCTTCCCCAAGAAGTGGGGTGTCGCTCATTATCGGCAGACCTTCCTCAGGTAAGTCAACCTTTCT
CAATGCCGTGTGCGGGTACAAGGTGTCCATAGTTTCCCCTATACCTCAGACAACCCGTAACACGGTGCGCGGCATCGTAA
ATATAGAATCCGACCAAATTGTCTTTATGGACACCCCGGGGTATCACCGGTCTGACAGAAAATTTAATCTGCGCCTGCAG
TCCCTTGTGCACAGTAATGTAAAGGATGCTGATGTGCTGTTGTACCTAGTAGACGCTACCCGTCAATTTGGAGAAGAAGA
AGCAGCCATCTGTGCATTGCTTGCCCCGTATCAAAAAACGCGCGTATTGCTTGCCTTCAATAAAGTGGATGTCCTTCACA
ATTCGACCTCGTGCGACGAGCATGCCTTTTTACACAGGCAAGGCAGCGTGCTGCGGGCCGGCAGCCTGGGACGAGCGCTA
CACGCCGCACTCCCCCACCTCCCTGCTGATCGGGTATTTACAATATCTGCCCTGCACCAGGTTGGGCTCGATGCCCTCAT
GCGCACGCTGAGAGATCTCTTGCCAGAAGCGGCGCCTCTGTACCCTCAGGATTGCTATACGGATCAGACCATCGCCTTTC
GCGTCACTGAGCTCATCCGAGAACAGGCAATCGCACGCTGCCGGGACGAACTGCCGCACGCACTATACGCCGGAGTGGAA
GACATGGAGCTGCGCCGCGGCAAGCGGGAACTGTGGTGCCGTGCGTTTCTTGCAGTAGAACGGGAAAGTCAAAAGGCAGT
GCTCGTGGGGAAGAAAGGTGCAGTTATTCGCGCCATACGGCTAGATGCCATCCGCGCGCTACGCACACTCCTCCCCTACC
ATATTTCCCTTGATATACGAGTGAAGGTAGACCGCAGCTGGAGACAACGCGACCACACACTCAGCTCCCTTCTGTACTAG

Upstream 100 bases:

>100_bases
CACGCGCGGGAGGGTTAGATATCCCACAGCTTTTTGCTGCCGCGTGCCGCTGCACGGACTGCAGTGGTAGCGTCTTTCCT
TTATACTCAGCACTGTGCAT

Downstream 100 bases:

>100_bases
GATGACCGGTGCCCAAATGAGGAATTCGCCGCAGGGGCGGGCCGCTCAAGGCGTATAGTTACTGAAGGTTCGTCACACAC
AGCCGGAGGTCCATAATACT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MVTDGASPRSGVSLIIGRPSSGKSTFLNAVCGYKVSIVSPIPQTTRNTVRGIVNIESDQIVFMDTPGYHRSDRKFNLRLQ
SLVHSNVKDADVLLYLVDATRQFGEEEAAICALLAPYQKTRVLLAFNKVDVLHNSTSCDEHAFLHRQGSVLRAGSLGRAL
HAALPHLPADRVFTISALHQVGLDALMRTLRDLLPEAAPLYPQDCYTDQTIAFRVTELIREQAIARCRDELPHALYAGVE
DMELRRGKRELWCRAFLAVERESQKAVLVGKKGAVIRAIRLDAIRALRTLLPYHISLDIRVKVDRSWRQRDHTLSSLLY

Sequences:

>Translated_319_residues
MVTDGASPRSGVSLIIGRPSSGKSTFLNAVCGYKVSIVSPIPQTTRNTVRGIVNIESDQIVFMDTPGYHRSDRKFNLRLQ
SLVHSNVKDADVLLYLVDATRQFGEEEAAICALLAPYQKTRVLLAFNKVDVLHNSTSCDEHAFLHRQGSVLRAGSLGRAL
HAALPHLPADRVFTISALHQVGLDALMRTLRDLLPEAAPLYPQDCYTDQTIAFRVTELIREQAIARCRDELPHALYAGVE
DMELRRGKRELWCRAFLAVERESQKAVLVGKKGAVIRAIRLDAIRALRTLLPYHISLDIRVKVDRSWRQRDHTLSSLLY
>Mature_319_residues
MVTDGASPRSGVSLIIGRPSSGKSTFLNAVCGYKVSIVSPIPQTTRNTVRGIVNIESDQIVFMDTPGYHRSDRKFNLRLQ
SLVHSNVKDADVLLYLVDATRQFGEEEAAICALLAPYQKTRVLLAFNKVDVLHNSTSCDEHAFLHRQGSVLRAGSLGRAL
HAALPHLPADRVFTISALHQVGLDALMRTLRDLLPEAAPLYPQDCYTDQTIAFRVTELIREQAIARCRDELPHALYAGVE
DMELRRGKRELWCRAFLAVERESQKAVLVGKKGAVIRAIRLDAIRALRTLLPYHISLDIRVKVDRSWRQRDHTLSSLLY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Escherichia coli, GI1788919, Length=312, Percent_Identity=30.7692307692308, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_TREPA (O83552)

Other databases:

- EMBL:   AE000520
- PIR:   B71312
- RefSeq:   NP_218980.1
- ProteinModelPortal:   O83552
- SMR:   O83552
- IntAct:   O83552
- GeneID:   2610730
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0541
- NMPDR:   fig|243276.1.peg.539
- TIGR:   TP_0541
- HOGENOM:   HBG561652
- OMA:   AKDWQRD
- ProtClustDB:   PRK00089
- BioCyc:   TPAL243276:TP_0541-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 35743; Mature: 35743

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTDGASPRSGVSLIIGRPSSGKSTFLNAVCGYKVSIVSPIPQTTRNTVRGIVNIESDQI
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHEEEEECCCCE
VFMDTPGYHRSDRKFNLRLQSLVHSNVKDADVLLYLVDATRQFGEEEAAICALLAPYQKT
EEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHEEEEEHHHHHHCCHHHHHHHHHCCCCCC
RVLLAFNKVDVLHNSTSCDEHAFLHRQGSVLRAGSLGRALHAALPHLPADRVFTISALHQ
EEEEEEEEEHEEECCCCCCHHHHHHCCCCEEECCCHHHHHHHHCCCCCCCCEEHHHHHHH
VGLDALMRTLRDLLPEAAPLYPQDCYTDQTIAFRVTELIREQAIARCRDELPHALYAGVE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCH
DMELRRGKRELWCRAFLAVERESQKAVLVGKKGAVIRAIRLDAIRALRTLLPYHISLDIR
HHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHHHHHHCCEEEEEEEE
VKVDRSWRQRDHTLSSLLY
EEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVTDGASPRSGVSLIIGRPSSGKSTFLNAVCGYKVSIVSPIPQTTRNTVRGIVNIESDQI
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHEEEEECCCCE
VFMDTPGYHRSDRKFNLRLQSLVHSNVKDADVLLYLVDATRQFGEEEAAICALLAPYQKT
EEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHEEEEEHHHHHHCCHHHHHHHHHCCCCCC
RVLLAFNKVDVLHNSTSCDEHAFLHRQGSVLRAGSLGRALHAALPHLPADRVFTISALHQ
EEEEEEEEEHEEECCCCCCHHHHHHCCCCEEECCCHHHHHHHHCCCCCCCCEEHHHHHHH
VGLDALMRTLRDLLPEAAPLYPQDCYTDQTIAFRVTELIREQAIARCRDELPHALYAGVE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCH
DMELRRGKRELWCRAFLAVERESQKAVLVGKKGAVIRAIRLDAIRALRTLLPYHISLDIR
HHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHHHHHHCCEEEEEEEE
VKVDRSWRQRDHTLSSLLY
EEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876