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The map label for this gene is spoIIAA2 [H]

Identifier: 189025768

GI number: 189025768

Start: 583120

End: 583491

Strand: Direct

Name: spoIIAA2 [H]

Synonym: TPASS_0540

Alternate gene names: 189025768

Gene position: 583120-583491 (Clockwise)

Preceding gene: 189025767

Following gene: 189025769

Centisome position: 51.18

GC content: 50.27

Gene sequence:

>372_bases
GTGCCTATGGAGTTGAAGGTCCGTCAGAGTGGCGGAATATGTGTCGTAGACATCAGTGGGGACATGGATCTGTATCATTC
CTACAAGCTTAAAGACCTTGTGCTGAAGTTGTTCGATAGGGGCCCGCGCTGTATCGTCATTGACCTTGAGGCGGTAGAGT
ATATCGATTCCTCAGGGATTGGCGTTCTCATCTATCTGTGTTCGACAGTGAAAAAGTTAAAAATCCACTTCTTTATCTCA
GGTGTGCACGGCTCTGTAAAGAAAGTGATTGAGCTCACCCGGCTGCTGAATTATTTTCCCATCGCTGAAAGCGTAGACGA
GGCTCTTGCAAGGGCCCGATCCTCTGCACCGCCGCAGACCGGCTCCCTGTAG

Upstream 100 bases:

>100_bases
TACTTCCAGCTTTTTTAGAATGGGCCGTGCAGCGTCCCGTGGGTCTGTGTGCGCCTGGTTTCTATCGGAAAAATGCGGGG
CTTGGTGCCCATGAGAGTAG

Downstream 100 bases:

>100_bases
GTTTTTCCTCGTCATGGGTTGAACCCTCCCACGCGCGGGAGGGTTAGATATCCCACAGCTTTTTGCTGCCGCGTGCCGCT
GCACGGACTGCAGTGGTAGC

Product: anti-sigma F factor antagonist

Products: NA

Alternate protein names: Anti-anti-sigma-B factor [H]

Number of amino acids: Translated: 123; Mature: 122

Protein sequence:

>123_residues
MPMELKVRQSGGICVVDISGDMDLYHSYKLKDLVLKLFDRGPRCIVIDLEAVEYIDSSGIGVLIYLCSTVKKLKIHFFIS
GVHGSVKKVIELTRLLNYFPIAESVDEALARARSSAPPQTGSL

Sequences:

>Translated_123_residues
MPMELKVRQSGGICVVDISGDMDLYHSYKLKDLVLKLFDRGPRCIVIDLEAVEYIDSSGIGVLIYLCSTVKKLKIHFFIS
GVHGSVKKVIELTRLLNYFPIAESVDEALARARSSAPPQTGSL
>Mature_122_residues
PMELKVRQSGGICVVDISGDMDLYHSYKLKDLVLKLFDRGPRCIVIDLEAVEYIDSSGIGVLIYLCSTVKKLKIHFFISG
VHGSVKKVIELTRLLNYFPIAESVDEALARARSSAPPQTGSL

Specific function: Positive regulator of sigma-B activity. Non- phosphorylated rsbV binds to rsbW, preventing its association with sigma-B. When phosphorylated, releases rsbW, which is then free to complex with and inactivate sigma-B [H]

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003658
- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 13599; Mature: 13468

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMELKVRQSGGICVVDISGDMDLYHSYKLKDLVLKLFDRGPRCIVIDLEAVEYIDSSGI
CCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCC
GVLIYLCSTVKKLKIHFFISGVHGSVKKVIELTRLLNYFPIAESVDEALARARSSAPPQT
CHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
GSL
CCC
>Mature Secondary Structure 
PMELKVRQSGGICVVDISGDMDLYHSYKLKDLVLKLFDRGPRCIVIDLEAVEYIDSSGI
CCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCC
GVLIYLCSTVKKLKIHFFISGVHGSVKKVIELTRLLNYFPIAESVDEALARARSSAPPQT
CHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
GSL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]