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The map label for this gene is mviN

Identifier: 189025746

GI number: 189025746

Start: 557759

End: 559339

Strand: Reverse

Name: mviN

Synonym: TPASS_0516

Alternate gene names: 189025746

Gene position: 559339-557759 (Counterclockwise)

Preceding gene: 189025747

Following gene: 189025740

Centisome position: 49.09

GC content: 41.87

Gene sequence:

>1581_bases
ATGAAAAGCAAGAGTTCTTTGTTGAAAAGTGGGTTGCTGCTTTCTCTTTTAACACTTGTCTCTCGTGTATTGGGTTTAGC
GCGAGAAGTAGTGAAGTCTACGCTTATGGGGACCAGTGCGACAGCAGATGCATTTACCGTTGCATTTATGATCCCAAACC
TTTTCCGCCGACTGTTTGCAGAAAACGCCATAAGTGTTGCCTTCATTCCCGTCTTCACACAGCACTACTCAATGCCGAGT
TCAGCGCAAGTGCCATGTTCTTCTAAAACGAAGGAGTTTCTTTCAGCTATCTTCACACTGATGAGTAGTGTCACTGCAAG
CATTTCTCTTATCGGTATACTCGGTGCTCCGTACATCGTGCGATTATTTGACACTGATCAGTCATTAACCGTTTCATTAA
CCCGCTTGATGTTTCCCTATTTATGGATGATCTCTCTCGCAGCTTTCTTTCAAGGTATGCTGCACAGTATTAAGGTATTT
GTCCCCTCAGGATGTACCCCAATATTTTTTAATGTCAGTGTCATTTTTTCGATGTACTTTCTGAATGTGTCACATATGAA
CGTGGCTATTGCTGCAGCAATAGGTGTTCTTATAGGAGGATGTGCGCAAGCACTCTTCCAGCTAATATTTGTATATATGC
ATGGGTTTCGTTTTACGCTCCAGTCTCCTTTAAAAGCAATGCACGATGAAGGTGTGCGACGAATCATTGCGTTACTTCTA
CCGACAACTGTTGGCATTGCAACCTATCTTCTAAATGACCTGGTGTGTACTGCGCTTGCAACCTCTGTTGAGATAGGAGT
TGCTGCGAGTGTGCAATATTCACTTCGTATACAAGAACTTTTATTAGGAATATTTATCGTTTCTCTAAGCTCTGTGGTAC
TTCCTGATCTTTCTTTCCATGTTATGAGAAAAGATTGGCAATCGTTTGAGGACCTCCTGATAACAGCGATAAAAATCGTC
ATGCTTATTACAATTCCTGCGACATTTTTCGTGTTATTTTCAAGTGACCGTATCATAACGCTCGTGTATAAAAATGCTAT
TTTTAACGAACTATCCGTGCGCATGACCGCTACCATATTTCGATGGCATAGCGTGGGAATGCTTGCTATTGCGCTGAATC
GCGTTCTCATCTCCGCCTTTTACGCGCAGCACAACTCTTTTGCCCCTATGATTGCAGGAACTATTTCATTTGTGACAAAT
ATCATTTTAGCAACACTGCTCTTTATTCCCTTAGGAGGTAAGGGCATTGCATTTTCTCTGAGCGCGGCGAGTATGGTACA
GACCGTTTTTTTATGGATGTTTTTAAAACGATCGTGGCAGATAACTATCCCTTCACTGTATAAAACTTCCCTTTACTATG
GAGTGAAAATAACTTTATTTTCTGTAATCGCGCTGGTACCCACATGGGCAAGTTCTTTTTTTACGGCGTATTTTTTTCCT
GGCTCCCATAAAATAATTTCTCACGGTGTCCCCTTATGCGTTGAGGCTCTTATTTTTTCGTGTACTGGCTGCATACTCCT
TTTACTTTCACGGGACGAATTTGCTTACAAAGCATTACGCTCCATACGTTTTTGCCGGTAA

Upstream 100 bases:

>100_bases
TTGCTGTTACCCATGTACACTGTTGTATGTCTTCAAACTATGCGGTAGGTTCAACGCGCTCTAGGGGAGCGTACGTTACG
CTGTACAAAAAAGGTAAGAG

Downstream 100 bases:

>100_bases
GATCACTTACACTCTAGATACCAACTTCAAACATACCTGGTGTTTTTCTCGCACGCGTTCTCACCATCGGTAATGGATTC
CAATTTATTGAAAGACTAAT

Product: virulence factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MKSKSSLLKSGLLLSLLTLVSRVLGLAREVVKSTLMGTSATADAFTVAFMIPNLFRRLFAENAISVAFIPVFTQHYSMPS
SAQVPCSSKTKEFLSAIFTLMSSVTASISLIGILGAPYIVRLFDTDQSLTVSLTRLMFPYLWMISLAAFFQGMLHSIKVF
VPSGCTPIFFNVSVIFSMYFLNVSHMNVAIAAAIGVLIGGCAQALFQLIFVYMHGFRFTLQSPLKAMHDEGVRRIIALLL
PTTVGIATYLLNDLVCTALATSVEIGVAASVQYSLRIQELLLGIFIVSLSSVVLPDLSFHVMRKDWQSFEDLLITAIKIV
MLITIPATFFVLFSSDRIITLVYKNAIFNELSVRMTATIFRWHSVGMLAIALNRVLISAFYAQHNSFAPMIAGTISFVTN
IILATLLFIPLGGKGIAFSLSAASMVQTVFLWMFLKRSWQITIPSLYKTSLYYGVKITLFSVIALVPTWASSFFTAYFFP
GSHKIISHGVPLCVEALIFSCTGCILLLLSRDEFAYKALRSIRFCR

Sequences:

>Translated_526_residues
MKSKSSLLKSGLLLSLLTLVSRVLGLAREVVKSTLMGTSATADAFTVAFMIPNLFRRLFAENAISVAFIPVFTQHYSMPS
SAQVPCSSKTKEFLSAIFTLMSSVTASISLIGILGAPYIVRLFDTDQSLTVSLTRLMFPYLWMISLAAFFQGMLHSIKVF
VPSGCTPIFFNVSVIFSMYFLNVSHMNVAIAAAIGVLIGGCAQALFQLIFVYMHGFRFTLQSPLKAMHDEGVRRIIALLL
PTTVGIATYLLNDLVCTALATSVEIGVAASVQYSLRIQELLLGIFIVSLSSVVLPDLSFHVMRKDWQSFEDLLITAIKIV
MLITIPATFFVLFSSDRIITLVYKNAIFNELSVRMTATIFRWHSVGMLAIALNRVLISAFYAQHNSFAPMIAGTISFVTN
IILATLLFIPLGGKGIAFSLSAASMVQTVFLWMFLKRSWQITIPSLYKTSLYYGVKITLFSVIALVPTWASSFFTAYFFP
GSHKIISHGVPLCVEALIFSCTGCILLLLSRDEFAYKALRSIRFCR
>Mature_526_residues
MKSKSSLLKSGLLLSLLTLVSRVLGLAREVVKSTLMGTSATADAFTVAFMIPNLFRRLFAENAISVAFIPVFTQHYSMPS
SAQVPCSSKTKEFLSAIFTLMSSVTASISLIGILGAPYIVRLFDTDQSLTVSLTRLMFPYLWMISLAAFFQGMLHSIKVF
VPSGCTPIFFNVSVIFSMYFLNVSHMNVAIAAAIGVLIGGCAQALFQLIFVYMHGFRFTLQSPLKAMHDEGVRRIIALLL
PTTVGIATYLLNDLVCTALATSVEIGVAASVQYSLRIQELLLGIFIVSLSSVVLPDLSFHVMRKDWQSFEDLLITAIKIV
MLITIPATFFVLFSSDRIITLVYKNAIFNELSVRMTATIFRWHSVGMLAIALNRVLISAFYAQHNSFAPMIAGTISFVTN
IILATLLFIPLGGKGIAFSLSAASMVQTVFLWMFLKRSWQITIPSLYKTSLYYGVKITLFSVIALVPTWASSFFTAYFFP
GSHKIISHGVPLCVEALIFSCTGCILLLLSRDEFAYKALRSIRFCR

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family

Homologues:

Organism=Escherichia coli, GI1787309, Length=443, Percent_Identity=27.5395033860045, Blast_Score=155, Evalue=7e-39,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): MVIN_TREPA (O83529)

Other databases:

- EMBL:   AE000520
- PIR:   C71315
- RefSeq:   NP_218957.1
- ProteinModelPortal:   O83529
- IntAct:   O83529
- GeneID:   2611568
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0516
- NMPDR:   fig|243276.1.peg.516
- TIGR:   TP_0516
- HOGENOM:   HBG731814
- OMA:   MLKITFP
- ProtClustDB:   CLSK218738
- BioCyc:   TPAL243276:TP_0516-MONOMER
- InterPro:   IPR004268
- PRINTS:   PR01806
- TIGRFAMs:   TIGR01695

Pfam domain/function: PF03023 MVIN

EC number: NA

Molecular weight: Translated: 58053; Mature: 58053

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x20a20714)-; HASH(0x1fe2bcfc)-; HASH(0x1ed0ad7c)-; HASH(0x1fdbf7c8)-; HASH(0x20e7c324)-; HASH(0x1fd4a108)-; HASH(0x20fd61d8)-; HASH(0x2112eed4)-; HASH(0x2129f738)-; HASH(0x20fd631c)-; HASH(0x20eb0aa4)-; HASH(0x20e7c2f4)-; HASH(0x20e7c1a4)-; HASH(0x20d290d8)-; HASH(0x21272d28)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCH
>Mature Secondary Structure
MKSKSSLLKSGLLLSLLTLVSRVLGLAREVVKSTLMGTSATADAFTVAFMIPNLFRRLFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ENAISVAFIPVFTQHYSMPSSAQVPCSSKTKEFLSAIFTLMSSVTASISLIGILGAPYIV
CCCCEEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
RLFDTDQSLTVSLTRLMFPYLWMISLAAFFQGMLHSIKVFVPSGCTPIFFNVSVIFSMYF
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHH
LNVSHMNVAIAAAIGVLIGGCAQALFQLIFVYMHGFRFTLQSPLKAMHDEGVRRIIALLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PTTVGIATYLLNDLVCTALATSVEIGVAASVQYSLRIQELLLGIFIVSLSSVVLPDLSFH
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VMRKDWQSFEDLLITAIKIVMLITIPATFFVLFSSDRIITLVYKNAIFNELSVRMTATIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEHHHHHHHHHHHHHHHHH
RWHSVGMLAIALNRVLISAFYAQHNSFAPMIAGTISFVTNIILATLLFIPLGGKGIAFSL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEH
SAASMVQTVFLWMFLKRSWQITIPSLYKTSLYYGVKITLFSVIALVPTWASSFFTAYFFP
HHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
GSHKIISHGVPLCVEALIFSCTGCILLLLSRDEFAYKALRSIRFCR
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876