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The map label for this gene is ileS

Identifier: 189025684

GI number: 189025684

Start: 480454

End: 483729

Strand: Direct

Name: ileS

Synonym: TPASS_0452

Alternate gene names: 189025684

Gene position: 480454-483729 (Clockwise)

Preceding gene: 189025682

Following gene: 189025685

Centisome position: 42.17

GC content: 48.84

Gene sequence:

>3276_bases
ATGTATACGCCTGTGGACCCAAAGGTTGATTTTGTCGCGCAGGAGCGGCGTATTCTCGCCTTTTGGCGGGAACGCCGGGT
GTTTGAGCAGTCTGTGGCGCAGCGTGCGCAGGGGAAGTCTTATGTTTTCTTTGACGGTCCCCCTTTTGCAACTGGACTGC
CACATTTTGGTCACTTTGTGCCCAGCACGATTAAGGATATTATTCCGCGCTATCAGACAATGCGTGGTGCGTACGTGCCG
CGTCGCTTTGGATGGGATTGTCATGGTCTGCCCATTGAACACCTGATTGAGCAAGAGCTCAATTTGAATTCAAAAAGTGA
TGTTGAGTCGTATGGTGTCAGCGCGTTTAACGCGGCATGTCGCTCCAGTGTGCTGCGATATGTGAAGGAGTGGCAGCGCA
CACTCACGCGTCTTGGGCGCTGGGTTGACTTCGATAATGACTATAAAACCATGGATGTCTGCTACATGGAGTCCGTGTGG
TGGGTTGTGGCGCAGCTATGGCAGCGAAAACTGCTGTATGAAGGTTATAAAATACTCCCGTACTGTCCACGGTGTGCGAC
AGCACTTTCTAATCACGAATTGAATTTAGGTGGATATCAGGATGTGTCTGATCCTGCCATTACTGTGCGTTTTGAGTGTA
CATCTGTTGTTCCTGGTAGTCCTGCTGCACGGGAGTTTTGTGCGGCAGCGTCTTGGGGAAGTGCATCACTTCCTGCGCAT
ACGTGCTTTCTTGCATGGACCACCACGCCTTGGACGCTTCCGTGCAACGCAGCGCTTGCGCTGGGACCACAAATTTTGTA
CGTGCTAATAGAGGCGAATGATGAGCACTATATTTTGGCTCGTTCTCGTCTTGAATTCTATTATCCAGATTCGTCTGCGT
ACCGCGTAGTGTGGGAAAAAAGAGGTGAACATCTTGCGGGGATTCGCTATCGGCCGCTTTTTTCTTATCCTGTGTTTGGG
CAGGGACCGGATCCTTCTGTACAAGGAGATTCAGAGGAGGGATTGTTCTGTACGCGAGTTGCGGATTTTGTTTCTACTGA
AGACGGCACTGGTGTTGTACACGTCGCACCTGCGTTCGGAGAGGATGATTATGAAGTATTTAAGGATGCGGGTATTTCGA
TTCAGTGTCCTCTTGATGCAGAGTGTCGCTTTACCGCAGAGGTTGCAGATTATCAGGGGCTTTTTGTAAAAGCTGCTGAT
AAGGCTATTATTGCACGTGTGCAGAAACAGGGAGCGTTATTTAGACGCGAACAGATTTCGCACGCATATCCACACTGTTG
GCGTTGTGCGAGTCCACTTATTTACCGTGCGGTGCACAGTTGGTTTGTTGCAGTTGAGAAGATAAAGGATAAAATGCTTG
CGGCGAATGCATCCATTTGCTGGCAGCCATCGCACATACGTGATGGCCGTTTTGGTAAGTGGCTTGTGTGTGCAAGAGAT
TGGGCAATTAGTCGGGATCGTTATTGGGGGAATCCGCTTCCTATTTGGCGGTGTGTGCACTGCGGTGCAACAGATTGCAT
TGGCAGTCGTACGCAGTTATATGAACGTTCCGGCATGTTGCTTGAAGATTTGCATAAGCACGTTGTAGATATGGTAACAA
TTCCTTGCGCCTGTGGGAGTGTGATGCGACGCGTTCCTGAGGTGCTAGATTGTTGGTTTGAATCTGGTGCAATGCCTTAT
GCGCAGCAGCACTATCCGTTTGAACATGCAACTGACTTTGAGCGGTATTTCCCTGCTCATTTTATCTCTGAAGGGTTAGA
TCAAACGCGAGGGTGGTTTTACACCCTTACCATCTTGGCTGTGGCACTCTTTGAGCGTCCTGCGTTTGAAAACTGTATCG
TTACGGGGTTGGTACTTGCGTCTGATGGAAAGAAGATGTCCAAGGCCCTGCGCAATTATGCGGATCCAAATGAAGTCATG
GATCGCTACGGTGCTGACGCGCTCCGCCTCTTTCTTGTTCGTTCTGCGGTTGTCCGTGCGGATGATTTAAAATATTCTGA
CGAAGGGGTGAAAGATATTTTGAAGACTGTGATTATCCCATTGTGGAATAGTTACAGTTTTTACGTTACGTATGCGAACA
TCGATGGTATCGATCCTCCTGTATGTGCAAAAGTTGACGGAATGGGTCAGGCGGTCACGCGTTTAGCGACGCATTTGAAT
AACCCGTTAGATCGTTGGATCTTGTCGCTGACAGAAAAATTGGTGCAAGACATTGCCTGTGCACTTGATGCTTACGATGT
ATCGAAAGTTGCGGATCCTATCGTTTCGTATGTAGATCAGCTGAACAACTGGTACATCCGCCGATCTCGAAGGAGATTTT
GGAAAAGCATCAACGATGAAGATAAACGATGTGCGTACAACACGTTGTATTGCGTGCTGAAAAGATGTGTGCTCGCTATT
GCTCCCGTGGTGCCATTCATCACCGAGAGTATATGGCAGAATATCCGCGCCGCGGATGATGTGCAGTCTGTGCATCTTGC
AGACTATCCTGTTTGTACACCAATGGTGCGAGACGATGCACTCGAGTTTAAAATGGAAACAGTGCAGCGAGTTGTTTCTA
TGGCGCGTGCGATCCGAGCGCAGTGTAACCTCAAAGTACGCCAGCCACTTAAAGCTATGCAGGTTATTACGCGTAACCCG
ATGGAGCGCTCAGCACTTCTTGAAATGGAAGAAGATGTGCTTGATGAGCTTAATGTAAAAGAGCTCGTGTTTCATGAGAA
AGAAGACGAGATAGTAGAGTACCGTGCAAAAGCGAATTTTAGAGTGCTCGGAAAAGAGCTTGGATCGAAGACAAAGCGTG
CAGCGCTCAGCATTGAGCGGTTGTCTTCTGCAGAAATTCAGGAGATACTCGAGGGGACGACGCTGTATCTGGATGTAGAT
GGAGATCGTTTGGAGTTGACTGAGGAAAAGATCCTGGTGCAAAGAATTGAGCGCGAGTCTTTGAAAGCGATAAATGAAGG
GACACTTACGGTCGCGCTTGACACCACCTTAACGGAAGATCTGCTCTTGGAAGGAGCAATTAGGGACTTGGTGCGCGGAG
TTCAAAATTTACGCAAGGAGCGTGGGTTTTCCTTAGTGGATCGTATTTGTCTGCGCGTTTTTTCTTCAGATCAGGATATA
GTGTGTGCCCGCAAGGCGTATGATCTGCATAGGTCATATATCGTTGGCGAGACGTTGGCAGCGCATGTGCAATGGGCACG
CGTGCGCGACGGTGCTTCTGCAGTGTACGTTAAATCGGACGCAGTACTATGGGAGGTGAGCATTGATAAGGCGTAG

Upstream 100 bases:

>100_bases
GAAAGGTGTGGCGCCGGTCATAAGACGTATGGGGAAAAGGAAGGACGAAAATGATATAATGCCTTACGCTCCTTATGCGA
TTCTGAGCAACGGAGGTTGT

Downstream 100 bases:

>100_bases
ATATCGTGGTTGTACGCAGGGAGCGTGGATAGTAAGTGTTGGTATGCTATTTGCATCGTGCACTTCAGGGGCGTGGAAGG
CATCAGTAGATCCGTTGGGG

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1091; Mature: 1091

Protein sequence:

>1091_residues
MYTPVDPKVDFVAQERRILAFWRERRVFEQSVAQRAQGKSYVFFDGPPFATGLPHFGHFVPSTIKDIIPRYQTMRGAYVP
RRFGWDCHGLPIEHLIEQELNLNSKSDVESYGVSAFNAACRSSVLRYVKEWQRTLTRLGRWVDFDNDYKTMDVCYMESVW
WVVAQLWQRKLLYEGYKILPYCPRCATALSNHELNLGGYQDVSDPAITVRFECTSVVPGSPAAREFCAAASWGSASLPAH
TCFLAWTTTPWTLPCNAALALGPQILYVLIEANDEHYILARSRLEFYYPDSSAYRVVWEKRGEHLAGIRYRPLFSYPVFG
QGPDPSVQGDSEEGLFCTRVADFVSTEDGTGVVHVAPAFGEDDYEVFKDAGISIQCPLDAECRFTAEVADYQGLFVKAAD
KAIIARVQKQGALFRREQISHAYPHCWRCASPLIYRAVHSWFVAVEKIKDKMLAANASICWQPSHIRDGRFGKWLVCARD
WAISRDRYWGNPLPIWRCVHCGATDCIGSRTQLYERSGMLLEDLHKHVVDMVTIPCACGSVMRRVPEVLDCWFESGAMPY
AQQHYPFEHATDFERYFPAHFISEGLDQTRGWFYTLTILAVALFERPAFENCIVTGLVLASDGKKMSKALRNYADPNEVM
DRYGADALRLFLVRSAVVRADDLKYSDEGVKDILKTVIIPLWNSYSFYVTYANIDGIDPPVCAKVDGMGQAVTRLATHLN
NPLDRWILSLTEKLVQDIACALDAYDVSKVADPIVSYVDQLNNWYIRRSRRRFWKSINDEDKRCAYNTLYCVLKRCVLAI
APVVPFITESIWQNIRAADDVQSVHLADYPVCTPMVRDDALEFKMETVQRVVSMARAIRAQCNLKVRQPLKAMQVITRNP
MERSALLEMEEDVLDELNVKELVFHEKEDEIVEYRAKANFRVLGKELGSKTKRAALSIERLSSAEIQEILEGTTLYLDVD
GDRLELTEEKILVQRIERESLKAINEGTLTVALDTTLTEDLLLEGAIRDLVRGVQNLRKERGFSLVDRICLRVFSSDQDI
VCARKAYDLHRSYIVGETLAAHVQWARVRDGASAVYVKSDAVLWEVSIDKA

Sequences:

>Translated_1091_residues
MYTPVDPKVDFVAQERRILAFWRERRVFEQSVAQRAQGKSYVFFDGPPFATGLPHFGHFVPSTIKDIIPRYQTMRGAYVP
RRFGWDCHGLPIEHLIEQELNLNSKSDVESYGVSAFNAACRSSVLRYVKEWQRTLTRLGRWVDFDNDYKTMDVCYMESVW
WVVAQLWQRKLLYEGYKILPYCPRCATALSNHELNLGGYQDVSDPAITVRFECTSVVPGSPAAREFCAAASWGSASLPAH
TCFLAWTTTPWTLPCNAALALGPQILYVLIEANDEHYILARSRLEFYYPDSSAYRVVWEKRGEHLAGIRYRPLFSYPVFG
QGPDPSVQGDSEEGLFCTRVADFVSTEDGTGVVHVAPAFGEDDYEVFKDAGISIQCPLDAECRFTAEVADYQGLFVKAAD
KAIIARVQKQGALFRREQISHAYPHCWRCASPLIYRAVHSWFVAVEKIKDKMLAANASICWQPSHIRDGRFGKWLVCARD
WAISRDRYWGNPLPIWRCVHCGATDCIGSRTQLYERSGMLLEDLHKHVVDMVTIPCACGSVMRRVPEVLDCWFESGAMPY
AQQHYPFEHATDFERYFPAHFISEGLDQTRGWFYTLTILAVALFERPAFENCIVTGLVLASDGKKMSKALRNYADPNEVM
DRYGADALRLFLVRSAVVRADDLKYSDEGVKDILKTVIIPLWNSYSFYVTYANIDGIDPPVCAKVDGMGQAVTRLATHLN
NPLDRWILSLTEKLVQDIACALDAYDVSKVADPIVSYVDQLNNWYIRRSRRRFWKSINDEDKRCAYNTLYCVLKRCVLAI
APVVPFITESIWQNIRAADDVQSVHLADYPVCTPMVRDDALEFKMETVQRVVSMARAIRAQCNLKVRQPLKAMQVITRNP
MERSALLEMEEDVLDELNVKELVFHEKEDEIVEYRAKANFRVLGKELGSKTKRAALSIERLSSAEIQEILEGTTLYLDVD
GDRLELTEEKILVQRIERESLKAINEGTLTVALDTTLTEDLLLEGAIRDLVRGVQNLRKERGFSLVDRICLRVFSSDQDI
VCARKAYDLHRSYIVGETLAAHVQWARVRDGASAVYVKSDAVLWEVSIDKA
>Mature_1091_residues
MYTPVDPKVDFVAQERRILAFWRERRVFEQSVAQRAQGKSYVFFDGPPFATGLPHFGHFVPSTIKDIIPRYQTMRGAYVP
RRFGWDCHGLPIEHLIEQELNLNSKSDVESYGVSAFNAACRSSVLRYVKEWQRTLTRLGRWVDFDNDYKTMDVCYMESVW
WVVAQLWQRKLLYEGYKILPYCPRCATALSNHELNLGGYQDVSDPAITVRFECTSVVPGSPAAREFCAAASWGSASLPAH
TCFLAWTTTPWTLPCNAALALGPQILYVLIEANDEHYILARSRLEFYYPDSSAYRVVWEKRGEHLAGIRYRPLFSYPVFG
QGPDPSVQGDSEEGLFCTRVADFVSTEDGTGVVHVAPAFGEDDYEVFKDAGISIQCPLDAECRFTAEVADYQGLFVKAAD
KAIIARVQKQGALFRREQISHAYPHCWRCASPLIYRAVHSWFVAVEKIKDKMLAANASICWQPSHIRDGRFGKWLVCARD
WAISRDRYWGNPLPIWRCVHCGATDCIGSRTQLYERSGMLLEDLHKHVVDMVTIPCACGSVMRRVPEVLDCWFESGAMPY
AQQHYPFEHATDFERYFPAHFISEGLDQTRGWFYTLTILAVALFERPAFENCIVTGLVLASDGKKMSKALRNYADPNEVM
DRYGADALRLFLVRSAVVRADDLKYSDEGVKDILKTVIIPLWNSYSFYVTYANIDGIDPPVCAKVDGMGQAVTRLATHLN
NPLDRWILSLTEKLVQDIACALDAYDVSKVADPIVSYVDQLNNWYIRRSRRRFWKSINDEDKRCAYNTLYCVLKRCVLAI
APVVPFITESIWQNIRAADDVQSVHLADYPVCTPMVRDDALEFKMETVQRVVSMARAIRAQCNLKVRQPLKAMQVITRNP
MERSALLEMEEDVLDELNVKELVFHEKEDEIVEYRAKANFRVLGKELGSKTKRAALSIERLSSAEIQEILEGTTLYLDVD
GDRLELTEEKILVQRIERESLKAINEGTLTVALDTTLTEDLLLEGAIRDLVRGVQNLRKERGFSLVDRICLRVFSSDQDI
VCARKAYDLHRSYIVGETLAAHVQWARVRDGASAVYVKSDAVLWEVSIDKA

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1054, Percent_Identity=40.607210626186, Blast_Score=793, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1054, Percent_Identity=40.607210626186, Blast_Score=793, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=856, Percent_Identity=26.4018691588785, Blast_Score=243, Evalue=5e-64,
Organism=Homo sapiens, GI268370297, Length=917, Percent_Identity=22.9007633587786, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI268370293, Length=917, Percent_Identity=22.9007633587786, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI268370295, Length=900, Percent_Identity=23, Blast_Score=151, Evalue=4e-36,
Organism=Homo sapiens, GI7661872, Length=193, Percent_Identity=27.979274611399, Blast_Score=68, Evalue=4e-11,
Organism=Escherichia coli, GI2367096, Length=919, Percent_Identity=26.7682263329706, Blast_Score=310, Evalue=4e-85,
Organism=Escherichia coli, GI1790708, Length=940, Percent_Identity=21.7021276595745, Blast_Score=152, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17541896, Length=1061, Percent_Identity=38.737040527804, Blast_Score=760, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=934, Percent_Identity=25.2676659528908, Blast_Score=254, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17510661, Length=890, Percent_Identity=21.685393258427, Blast_Score=159, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1050, Percent_Identity=39.2380952380952, Blast_Score=766, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=825, Percent_Identity=23.6363636363636, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI28574730, Length=1052, Percent_Identity=40.4942965779468, Blast_Score=798, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1052, Percent_Identity=40.4942965779468, Blast_Score=798, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1052, Percent_Identity=40.4942965779468, Blast_Score=798, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=817, Percent_Identity=24.8470012239902, Blast_Score=219, Evalue=9e-57,
Organism=Drosophila melanogaster, GI17864482, Length=891, Percent_Identity=21.9977553310887, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24653289, Length=891, Percent_Identity=21.9977553310887, Blast_Score=140, Evalue=4e-33,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_TREPA (O83466)

Other databases:

- EMBL:   AE000520
- PIR:   E71322
- RefSeq:   NP_218893.1
- ProteinModelPortal:   O83466
- SMR:   O83466
- IntAct:   O83466
- GeneID:   2611024
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0452
- NMPDR:   fig|243276.1.peg.452
- TIGR:   TP_0452
- HOGENOM:   HBG577712
- OMA:   VEYEVEK
- ProtClustDB:   PRK06039
- BioCyc:   TPAL243276:TP_0452-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 124243; Mature: 124243

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 628-628

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTPVDPKVDFVAQERRILAFWRERRVFEQSVAQRAQGKSYVFFDGPPFATGLPHFGHFV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHH
PSTIKDIIPRYQTMRGAYVPRRFGWDCHGLPIEHLIEQELNLNSKSDVESYGVSAFNAAC
HHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHCHHHHHHHH
RSSVLRYVKEWQRTLTRLGRWVDFDNDYKTMDVCYMESVWWVVAQLWQRKLLYEGYKILP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
YCPRCATALSNHELNLGGYQDVSDPAITVRFECTSVVPGSPAAREFCAAASWGSASLPAH
CCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCE
TCFLAWTTTPWTLPCNAALALGPQILYVLIEANDEHYILARSRLEFYYPDSSAYRVVWEK
EEEEEEECCCCCCCCCCHHHCCCEEEEEEEECCCCEEEEEECCEEEECCCCCCEEEEEHH
RGEHLAGIRYRPLFSYPVFGQGPDPSVQGDSEEGLFCTRVADFVSTEDGTGVVHVAPAFG
CCCCCCCCEECEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCEEEECCCCC
EDDYEVFKDAGISIQCPLDAECRFTAEVADYQGLFVKAADKAIIARVQKQGALFRREQIS
CCHHHHHHCCCCEEECCCCCCCEEEEEHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
HAYPHCWRCASPLIYRAVHSWFVAVEKIKDKMLAANASICWQPSHIRDGRFGKWLVCARD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEECC
WAISRDRYWGNPLPIWRCVHCGATDCIGSRTQLYERSGMLLEDLHKHVVDMVTIPCACGS
CCCCCCCCCCCCCHHHHHHHCCCHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VMRRVPEVLDCWFESGAMPYAQQHYPFEHATDFERYFPAHFISEGLDQTRGWFYTLTILA
HHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHH
VALFERPAFENCIVTGLVLASDGKKMSKALRNYADPNEVMDRYGADALRLFLVRSAVVRA
HHHHCCCCCCHHHHHHEEEECCCHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHH
DDLKYSDEGVKDILKTVIIPLWNSYSFYVTYANIDGIDPPVCAKVDGMGQAVTRLATHLN
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHC
NPLDRWILSLTEKLVQDIACALDAYDVSKVADPIVSYVDQLNNWYIRRSRRRFWKSINDE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DKRCAYNTLYCVLKRCVLAIAPVVPFITESIWQNIRAADDVQSVHLADYPVCTPMVRDDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCCCCCCHHHHHH
LEFKMETVQRVVSMARAIRAQCNLKVRQPLKAMQVITRNPMERSALLEMEEDVLDELNVK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHH
ELVFHEKEDEIVEYRAKANFRVLGKELGSKTKRAALSIERLSSAEIQEILEGTTLYLDVD
HHHHCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GDRLELTEEKILVQRIERESLKAINEGTLTVALDTTLTEDLLLEGAIRDLVRGVQNLRKE
CCEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
RGFSLVDRICLRVFSSDQDIVCARKAYDLHRSYIVGETLAAHVQWARVRDGASAVYVKSD
CCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
AVLWEVSIDKA
EEEEEEEECCC
>Mature Secondary Structure
MYTPVDPKVDFVAQERRILAFWRERRVFEQSVAQRAQGKSYVFFDGPPFATGLPHFGHFV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHH
PSTIKDIIPRYQTMRGAYVPRRFGWDCHGLPIEHLIEQELNLNSKSDVESYGVSAFNAAC
HHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHCHHHHHHHH
RSSVLRYVKEWQRTLTRLGRWVDFDNDYKTMDVCYMESVWWVVAQLWQRKLLYEGYKILP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
YCPRCATALSNHELNLGGYQDVSDPAITVRFECTSVVPGSPAAREFCAAASWGSASLPAH
CCCHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCE
TCFLAWTTTPWTLPCNAALALGPQILYVLIEANDEHYILARSRLEFYYPDSSAYRVVWEK
EEEEEEECCCCCCCCCCHHHCCCEEEEEEEECCCCEEEEEECCEEEECCCCCCEEEEEHH
RGEHLAGIRYRPLFSYPVFGQGPDPSVQGDSEEGLFCTRVADFVSTEDGTGVVHVAPAFG
CCCCCCCCEECEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCEEEECCCCC
EDDYEVFKDAGISIQCPLDAECRFTAEVADYQGLFVKAADKAIIARVQKQGALFRREQIS
CCHHHHHHCCCCEEECCCCCCCEEEEEHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
HAYPHCWRCASPLIYRAVHSWFVAVEKIKDKMLAANASICWQPSHIRDGRFGKWLVCARD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEECC
WAISRDRYWGNPLPIWRCVHCGATDCIGSRTQLYERSGMLLEDLHKHVVDMVTIPCACGS
CCCCCCCCCCCCCHHHHHHHCCCHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VMRRVPEVLDCWFESGAMPYAQQHYPFEHATDFERYFPAHFISEGLDQTRGWFYTLTILA
HHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHH
VALFERPAFENCIVTGLVLASDGKKMSKALRNYADPNEVMDRYGADALRLFLVRSAVVRA
HHHHCCCCCCHHHHHHEEEECCCHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHH
DDLKYSDEGVKDILKTVIIPLWNSYSFYVTYANIDGIDPPVCAKVDGMGQAVTRLATHLN
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHC
NPLDRWILSLTEKLVQDIACALDAYDVSKVADPIVSYVDQLNNWYIRRSRRRFWKSINDE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DKRCAYNTLYCVLKRCVLAIAPVVPFITESIWQNIRAADDVQSVHLADYPVCTPMVRDDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCCCCCCCHHHHHH
LEFKMETVQRVVSMARAIRAQCNLKVRQPLKAMQVITRNPMERSALLEMEEDVLDELNVK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHH
ELVFHEKEDEIVEYRAKANFRVLGKELGSKTKRAALSIERLSSAEIQEILEGTTLYLDVD
HHHHCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GDRLELTEEKILVQRIERESLKAINEGTLTVALDTTLTEDLLLEGAIRDLVRGVQNLRKE
CCEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
RGFSLVDRICLRVFSSDQDIVCARKAYDLHRSYIVGETLAAHVQWARVRDGASAVYVKSD
CCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
AVLWEVSIDKA
EEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876