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The map label for this gene is atpI1

Identifier: 189025662

GI number: 189025662

Start: 457882

End: 459750

Strand: Direct

Name: atpI1

Synonym: TPASS_0429

Alternate gene names: 189025662

Gene position: 457882-459750 (Clockwise)

Preceding gene: 189025661

Following gene: 189025663

Centisome position: 40.18

GC content: 53.24

Gene sequence:

>1869_bases
GTGATAGTTCCTATGAAAAAGGTAACGCTTCTGGTGCTCGGTTCTGAGCAAGAGCGTTCGCTGCAGGCGTTGCGTTCCTT
TGGTGCTGTGCATGTGCAGTTGCGGGAGTGTGCAAGTGAGCAACTTGCAGAGTTGCACGCGTTGGACGCTCGGTGCGTGC
AGGCCATTGCGCTCGTCACTGACGCTCAGACAAAGAATGTTACCCGAGGAGAGGAGTGTCGCGTTGCAGGTCAGGTGGTA
GAAGCAGCAGAGGCCGTGGAACAGATCGTACGTACTCATTCAGACCGCGTGGAACTTGCTCAGCGCATTGCGCAGTGCAT
TGCGCATCTGGAACGCTGTGAGCCGTGGGGGGATTTCGATCCGGCAGATGTGAGGGCACTCGCACAGCGGGGGATACATC
TTATCCCCGTGGAGCTTTCTGAGCGTTCATACCGCTGCTTGCCCGATGAGTTGCAGACGCTTTGTCTTGCTCGTCGCGGG
GGCTTGGTGCGCTGTGTGCTTGTGGCAGATAAACCGGGGCTGCCGCCATCTCTTCCTGCCGATGCGCGCGCGCTAGAATT
GCCAGACGTTTCTCCCGCTGATCTGTTTGTACGGCTCAGGCAGTTGCGTGAGGAGTGCGCTACGCTAACACAACGGCTTC
TTGCTTATTCGGAATACCAAGGGGCGATTCGCGCCTTGCGGCAGAAGATTGCCGCAGATATCGAGTTTGAGCGCGTGCAT
CTCAGTATGGTTTCGGTAGACGTCAGTCAGTGGCGTGAAACAGGAGAGACGTTGCGCATTGCGCACGTCAGTGGGTACCT
GCCTGTTTCCCGGGTGCGTGCCTTTTCTGAGTGTGCGCGGAAGGAAGCGTGGGCGTATTGCTGTGTAGACCCTATGCCTG
AGGATCCGGTACCTACACAGCTGAGAAATAACCGTTGGGTAAATTTGATTTCCCCGTTGATGAATTTCCTCGGCACTGTG
CCCGGCTATTGGGAGGTAGACATTTCTGGCTTCTTTTTGCTCTTTTTTGGCGTGTTCTTCTCAATCATCTTTGCGGACGC
AGGCTACGGCGCAGTCCTCACGCTTGTGTCCTTGGGAGGGATTGTTCTCAGCAAGAGAAAACATGCAGTGGTGAGTCCAG
CATGGTGCTTGGGACTATACTTAGGAACGCTCACGATGGTGTGGGGTGCGCTCGTGTGTAACTGGTTTGGTGTGCCTGTC
CAGTATGTGCCGGCGTCGCTCGCGCGTATTGCAGTTTGGGAGATTTCAGGCTTTGCGGATGCCGCCCAGCGGAATAAGAA
TCAGATGCACGTGTGTTTCTTTCTCGGTTTATTGCACCTGTGTCTCGGTCATTTGATCGTCGTGCGGCGCACCTTCCGTT
CCCTGAGGGTGCTTGCAGAGTTTGGTTCTCTTCTCATGTTGGGTGGTATGTACGTGGTAGTGCTCAACTTGATTGTTGAC
AAAGAGCGCTATCCGCTTACCGGCATGATTGTCGGGTCTATAATAGCGGGTTTTGTGCTGAATTTTATCTTTGTGAATTA
TCGGGTGAGTGTGCGGCAGAGTGTTGCAGACAGTATGAAAAACGTAATTAATGCGTTGCTGGGCATTGTAAATGTATTTG
CAGATGTCATGAGTTATATTCGGCTTTGGGCGGTGGGATTGGCCGGAGGGGCAATCAGTGCGACAGTTAATGAAATGACA
CACCCTCTGTTTGCCAATTTCCTGGCGTTCCTTGGGATAGTGCTACTGCTGTTTGGACACGGGCTGAATTACGTAATGAG
CATACTGTCGGTGATTGTGCACGGTGTGCGCTTGAATACCTTGGAGTTTTCTAATCATGTGGGTCTGATGTGGACAGGCA
TACGATATACTCCCTTTAGGGAGCGTTAG

Upstream 100 bases:

>100_bases
CGGTGTACCTCGGTGATCAGCAGGTTGCTGCAGTAGTGCGGGGGAAGATGTCTAAGAAGAATCTGGTAGACGTGAGTCGG
ATGGAACAAGAGGATACACG

Downstream 100 bases:

>100_bases
CATAGAAAGAGGTAGAAAAAGAGTGGAGGGCTCGTTATGAATTTTGGTATGTTTGGCGCCGCGGCGGTGCTGGGGATCTC
TGCGGTGGGTTCTGCGCTCG

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit I 1

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MIVPMKKVTLLVLGSEQERSLQALRSFGAVHVQLRECASEQLAELHALDARCVQAIALVTDAQTKNVTRGEECRVAGQVV
EAAEAVEQIVRTHSDRVELAQRIAQCIAHLERCEPWGDFDPADVRALAQRGIHLIPVELSERSYRCLPDELQTLCLARRG
GLVRCVLVADKPGLPPSLPADARALELPDVSPADLFVRLRQLREECATLTQRLLAYSEYQGAIRALRQKIAADIEFERVH
LSMVSVDVSQWRETGETLRIAHVSGYLPVSRVRAFSECARKEAWAYCCVDPMPEDPVPTQLRNNRWVNLISPLMNFLGTV
PGYWEVDISGFFLLFFGVFFSIIFADAGYGAVLTLVSLGGIVLSKRKHAVVSPAWCLGLYLGTLTMVWGALVCNWFGVPV
QYVPASLARIAVWEISGFADAAQRNKNQMHVCFFLGLLHLCLGHLIVVRRTFRSLRVLAEFGSLLMLGGMYVVVLNLIVD
KERYPLTGMIVGSIIAGFVLNFIFVNYRVSVRQSVADSMKNVINALLGIVNVFADVMSYIRLWAVGLAGGAISATVNEMT
HPLFANFLAFLGIVLLLFGHGLNYVMSILSVIVHGVRLNTLEFSNHVGLMWTGIRYTPFRER

Sequences:

>Translated_622_residues
MIVPMKKVTLLVLGSEQERSLQALRSFGAVHVQLRECASEQLAELHALDARCVQAIALVTDAQTKNVTRGEECRVAGQVV
EAAEAVEQIVRTHSDRVELAQRIAQCIAHLERCEPWGDFDPADVRALAQRGIHLIPVELSERSYRCLPDELQTLCLARRG
GLVRCVLVADKPGLPPSLPADARALELPDVSPADLFVRLRQLREECATLTQRLLAYSEYQGAIRALRQKIAADIEFERVH
LSMVSVDVSQWRETGETLRIAHVSGYLPVSRVRAFSECARKEAWAYCCVDPMPEDPVPTQLRNNRWVNLISPLMNFLGTV
PGYWEVDISGFFLLFFGVFFSIIFADAGYGAVLTLVSLGGIVLSKRKHAVVSPAWCLGLYLGTLTMVWGALVCNWFGVPV
QYVPASLARIAVWEISGFADAAQRNKNQMHVCFFLGLLHLCLGHLIVVRRTFRSLRVLAEFGSLLMLGGMYVVVLNLIVD
KERYPLTGMIVGSIIAGFVLNFIFVNYRVSVRQSVADSMKNVINALLGIVNVFADVMSYIRLWAVGLAGGAISATVNEMT
HPLFANFLAFLGIVLLLFGHGLNYVMSILSVIVHGVRLNTLEFSNHVGLMWTGIRYTPFRER
>Mature_622_residues
MIVPMKKVTLLVLGSEQERSLQALRSFGAVHVQLRECASEQLAELHALDARCVQAIALVTDAQTKNVTRGEECRVAGQVV
EAAEAVEQIVRTHSDRVELAQRIAQCIAHLERCEPWGDFDPADVRALAQRGIHLIPVELSERSYRCLPDELQTLCLARRG
GLVRCVLVADKPGLPPSLPADARALELPDVSPADLFVRLRQLREECATLTQRLLAYSEYQGAIRALRQKIAADIEFERVH
LSMVSVDVSQWRETGETLRIAHVSGYLPVSRVRAFSECARKEAWAYCCVDPMPEDPVPTQLRNNRWVNLISPLMNFLGTV
PGYWEVDISGFFLLFFGVFFSIIFADAGYGAVLTLVSLGGIVLSKRKHAVVSPAWCLGLYLGTLTMVWGALVCNWFGVPV
QYVPASLARIAVWEISGFADAAQRNKNQMHVCFFLGLLHLCLGHLIVVRRTFRSLRVLAEFGSLLMLGGMYVVVLNLIVD
KERYPLTGMIVGSIIAGFVLNFIFVNYRVSVRQSVADSMKNVINALLGIVNVFADVMSYIRLWAVGLAGGAISATVNEMT
HPLFANFLAFLGIVLLLFGHGLNYVMSILSVIVHGVRLNTLEFSNHVGLMWTGIRYTPFRER

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VATI1_TREPA (O83444)

Other databases:

- EMBL:   AE000520
- PIR:   B71326
- RefSeq:   NP_218869.1
- ProteinModelPortal:   O83444
- GeneID:   2610939
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0429
- NMPDR:   fig|243276.1.peg.428
- TIGR:   TP_0429
- HOGENOM:   HBG732011
- OMA:   YNNPSFA
- ProtClustDB:   PRK05771
- BioCyc:   TPAL243276:TP_0429-MONOMER
- BRENDA:   3.6.3.14
- InterPro:   IPR002490
- PANTHER:   PTHR11629

Pfam domain/function: PF01496 V_ATPase_I

EC number: 3.6.3.14

Molecular weight: Translated: 69078; Mature: 69078

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x201c05e8)-; HASH(0x20e8b7ec)-; HASH(0x20d4092c)-; HASH(0x1fd7c130)-; HASH(0x20695a50)-; HASH(0x1f501f40)-; HASH(0x1e1b455c)-; HASH(0x20924600)-;

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVPMKKVTLLVLGSEQERSLQALRSFGAVHVQLRECASEQLAELHALDARCVQAIALVT
CCCCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAQTKNVTRGEECRVAGQVVEAAEAVEQIVRTHSDRVELAQRIAQCIAHLERCEPWGDFD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PADVRALAQRGIHLIPVELSERSYRCLPDELQTLCLARRGGLVRCVLVADKPGLPPSLPA
HHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
DARALELPDVSPADLFVRLRQLREECATLTQRLLAYSEYQGAIRALRQKIAADIEFERVH
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LSMVSVDVSQWRETGETLRIAHVSGYLPVSRVRAFSECARKEAWAYCCVDPMPEDPVPTQ
HHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCC
LRNNRWVNLISPLMNFLGTVPGYWEVDISGFFLLFFGVFFSIIFADAGYGAVLTLVSLGG
CCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IVLSKRKHAVVSPAWCLGLYLGTLTMVWGALVCNWFGVPVQYVPASLARIAVWEISGFAD
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHH
AAQRNKNQMHVCFFLGLLHLCLGHLIVVRRTFRSLRVLAEFGSLLMLGGMYVVVLNLIVD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KERYPLTGMIVGSIIAGFVLNFIFVNYRVSVRQSVADSMKNVINALLGIVNVFADVMSYI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLWAVGLAGGAISATVNEMTHPLFANFLAFLGIVLLLFGHGLNYVMSILSVIVHGVRLNT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEE
LEFSNHVGLMWTGIRYTPFRER
EEECCCCCEEEECCCCCCCCCH
>Mature Secondary Structure
MIVPMKKVTLLVLGSEQERSLQALRSFGAVHVQLRECASEQLAELHALDARCVQAIALVT
CCCCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAQTKNVTRGEECRVAGQVVEAAEAVEQIVRTHSDRVELAQRIAQCIAHLERCEPWGDFD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PADVRALAQRGIHLIPVELSERSYRCLPDELQTLCLARRGGLVRCVLVADKPGLPPSLPA
HHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
DARALELPDVSPADLFVRLRQLREECATLTQRLLAYSEYQGAIRALRQKIAADIEFERVH
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LSMVSVDVSQWRETGETLRIAHVSGYLPVSRVRAFSECARKEAWAYCCVDPMPEDPVPTQ
HHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCC
LRNNRWVNLISPLMNFLGTVPGYWEVDISGFFLLFFGVFFSIIFADAGYGAVLTLVSLGG
CCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IVLSKRKHAVVSPAWCLGLYLGTLTMVWGALVCNWFGVPVQYVPASLARIAVWEISGFAD
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHH
AAQRNKNQMHVCFFLGLLHLCLGHLIVVRRTFRSLRVLAEFGSLLMLGGMYVVVLNLIVD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KERYPLTGMIVGSIIAGFVLNFIFVNYRVSVRQSVADSMKNVINALLGIVNVFADVMSYI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLWAVGLAGGAISATVNEMTHPLFANFLAFLGIVLLLFGHGLNYVMSILSVIVHGVRLNT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEE
LEFSNHVGLMWTGIRYTPFRER
EEECCCCCEEEECCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876