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The map label for this gene is kdtB

Identifier: 189025517

GI number: 189025517

Start: 299177

End: 299656

Strand: Direct

Name: kdtB

Synonym: TPASS_0283

Alternate gene names: 189025517

Gene position: 299177-299656 (Clockwise)

Preceding gene: 189025516

Following gene: 189025518

Centisome position: 26.26

GC content: 51.67

Gene sequence:

>480_bases
GTGAAGGCGATTTTCGCCGGTTCTTTTGATCCGCCTACCTTTGGGCATTTAGATCTTGTTCTGCGCGCGCGTAGTCTTTT
TGCAGAGGTCCACGTGTTGGTTGCGGTCAATGTTCAGAAAAGGTATTTGCTTTCAGAATGTGAGCGCGTTGATTTGATGC
GGCAAGTCCTTGGGGATCGTCCGGGTGTGTACGTCTTTCCTTGGCGTTCGCTTGTGGTTACGTACGCTCGAGATGTTGGT
GCGCGTGTGCTGGTTCGCGGTGTGAGAAATGCTACTGATTTCTGTCAGGAGTTTGATCTTGCATGGGTTCATCGTGCGCT
CGACGCTGGTTTAGAAACAGTTTTTTTGGCGGCAAAGCCCTGCTATGCTGCGCTTCGTTCCAGCATGGTACGCGAGGTTG
CTTCTTTCGGTGGTGATGTGTCTACTTTTGTCCCCCGTGTAGTTGCCCGCCTTTTGCAAGAGAAGTTTACGCAGGCGTGA

Upstream 100 bases:

>100_bases
TCCGCGAGGAGTTGACGGAGTGGGTGCGAATATAAATAGTGCTGCCTGTTTTTTGTGTAGTTCGCCGCATGTTCCTGAAC
AACGTGAGGGGTTGCCGTGC

Downstream 100 bases:

>100_bases
ATTGCATGAGCTGAGTATGTGATGATTCTTTTTCTCACTCGGTTGAGTGATCTTCGGGGCTGTGCTTTTAAAGTTCAGAA
AAGTTTTGAGCAAGGTTCTC

Product: lipopolysaccharide core biosynthesis protein

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKAIFAGSFDPPTFGHLDLVLRARSLFAEVHVLVAVNVQKRYLLSECERVDLMRQVLGDRPGVYVFPWRSLVVTYARDVG
ARVLVRGVRNATDFCQEFDLAWVHRALDAGLETVFLAAKPCYAALRSSMVREVASFGGDVSTFVPRVVARLLQEKFTQA

Sequences:

>Translated_159_residues
MKAIFAGSFDPPTFGHLDLVLRARSLFAEVHVLVAVNVQKRYLLSECERVDLMRQVLGDRPGVYVFPWRSLVVTYARDVG
ARVLVRGVRNATDFCQEFDLAWVHRALDAGLETVFLAAKPCYAALRSSMVREVASFGGDVSTFVPRVVARLLQEKFTQA
>Mature_159_residues
MKAIFAGSFDPPTFGHLDLVLRARSLFAEVHVLVAVNVQKRYLLSECERVDLMRQVLGDRPGVYVFPWRSLVVTYARDVG
ARVLVRGVRNATDFCQEFDLAWVHRALDAGLETVFLAAKPCYAALRSSMVREVASFGGDVSTFVPRVVARLLQEKFTQA

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=38.0645161290323, Blast_Score=105, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_TREPA (O83307)

Other databases:

- EMBL:   AE000520
- PIR:   F71343
- RefSeq:   NP_218724.1
- ProteinModelPortal:   O83307
- SMR:   O83307
- IntAct:   O83307
- GeneID:   2611699
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0283
- NMPDR:   fig|243276.1.peg.283
- TIGR:   TP_0283
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   CLSK218627
- BioCyc:   TPAL243276:TP_0283-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17805; Mature: 17805

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIFAGSFDPPTFGHLDLVLRARSLFAEVHVLVAVNVQKRYLLSECERVDLMRQVLGDR
CCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHCCC
PGVYVFPWRSLVVTYARDVGARVLVRGVRNATDFCQEFDLAWVHRALDAGLETVFLAAKP
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CYAALRSSMVREVASFGGDVSTFVPRVVARLLQEKFTQA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKAIFAGSFDPPTFGHLDLVLRARSLFAEVHVLVAVNVQKRYLLSECERVDLMRQVLGDR
CCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHCCC
PGVYVFPWRSLVVTYARDVGARVLVRGVRNATDFCQEFDLAWVHRALDAGLETVFLAAKP
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CYAALRSSMVREVASFGGDVSTFVPRVVARLLQEKFTQA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876