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The map label for this gene is comEB [H]

Identifier: 189025508

GI number: 189025508

Start: 291404

End: 291904

Strand: Reverse

Name: comEB [H]

Synonym: TPASS_0274

Alternate gene names: 189025508

Gene position: 291904-291404 (Counterclockwise)

Preceding gene: 189025509

Following gene: 189025506

Centisome position: 25.62

GC content: 56.09

Gene sequence:

>501_bases
ATGGGACAACGTGAGGAGTTGGTTACGCGACCGAGTTGGGATGAGTATTTTATGGAAGTGTGTCATGCAATTGCCAAGCG
TGCCACCTGCGATCGCGGACGCGCAGGCTGCGTCATAGCGCGCGATCACCATCTGCTTGTAACTGGGTATGCAGGCGCAC
CGCGAGGTCTCCTGCATTGTGACGAACATGGACACCAGCTACGCACGGTGCAGCATGAAGACGGGACGTGCACGCAGCAT
TGCGTTCGCACCGTGCACGCAGAGCAAAACGCCCTCTGCCAGGCAGCGCGTTTGGGCATCGGTCTAGAGGGCGCAACACT
CTACTGTACCATGACACCGTGCCGCACCTGTGCAATGCTCATCATTAACTGCGGCATTGTGCGTGTCGTTGCTGAGAAGC
GTTATCAGACTGCGACAGAAAGTATCATGCTGTTTGCACAAGCACAGATCGCGCTTGAGCACATATACCAAAATCCTGCT
GAGTACGGCACCCCCTCATAG

Upstream 100 bases:

>100_bases
CGCACGAAGTGAGCGATGTTTAAACTCACCCGCCAGAGTGTGCTGCGCACCGCAGCACAAGGGCATGTGCATCTTTAAGG
GAAAAAGGGAGCATACGATA

Downstream 100 bases:

>100_bases
ACTGCGGGGTTGTTATTTCTCTCGAACACAATGAACATTACGATTTCCACGGAGAGAAGAGCTCGCCGACGGTGTGCGCG
CGGGATTGTGCACGCATCTG

Product: deoxycytidylate deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MGQREELVTRPSWDEYFMEVCHAIAKRATCDRGRAGCVIARDHHLLVTGYAGAPRGLLHCDEHGHQLRTVQHEDGTCTQH
CVRTVHAEQNALCQAARLGIGLEGATLYCTMTPCRTCAMLIINCGIVRVVAEKRYQTATESIMLFAQAQIALEHIYQNPA
EYGTPS

Sequences:

>Translated_166_residues
MGQREELVTRPSWDEYFMEVCHAIAKRATCDRGRAGCVIARDHHLLVTGYAGAPRGLLHCDEHGHQLRTVQHEDGTCTQH
CVRTVHAEQNALCQAARLGIGLEGATLYCTMTPCRTCAMLIINCGIVRVVAEKRYQTATESIMLFAQAQIALEHIYQNPA
EYGTPS
>Mature_165_residues
GQREELVTRPSWDEYFMEVCHAIAKRATCDRGRAGCVIARDHHLLVTGYAGAPRGLLHCDEHGHQLRTVQHEDGTCTQHC
VRTVHAEQNALCQAARLGIGLEGATLYCTMTPCRTCAMLIINCGIVRVVAEKRYQTATESIMLFAQAQIALEHIYQNPAE
YGTPS

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321938, Length=149, Percent_Identity=38.255033557047, Blast_Score=101, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 18410; Mature: 18279

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
6.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQREELVTRPSWDEYFMEVCHAIAKRATCDRGRAGCVIARDHHLLVTGYAGAPRGLLHC
CCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCCCCCCCEEC
DEHGHQLRTVQHEDGTCTQHCVRTVHAEQNALCQAARLGIGLEGATLYCTMTPCRTCAML
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHH
IINCGIVRVVAEKRYQTATESIMLFAQAQIALEHIYQNPAEYGTPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GQREELVTRPSWDEYFMEVCHAIAKRATCDRGRAGCVIARDHHLLVTGYAGAPRGLLHC
CCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCCCCCCCEEC
DEHGHQLRTVQHEDGTCTQHCVRTVHAEQNALCQAARLGIGLEGATLYCTMTPCRTCAML
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHH
IINCGIVRVVAEKRYQTATESIMLFAQAQIALEHIYQNPAEYGTPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]