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The map label for this gene is bioY

Identifier: 189025461

GI number: 189025461

Start: 237825

End: 238640

Strand: Reverse

Name: bioY

Synonym: TPASS_0228

Alternate gene names: 189025461

Gene position: 238640-237825 (Counterclockwise)

Preceding gene: 189025492

Following gene: 189025460

Centisome position: 20.94

GC content: 55.64

Gene sequence:

>816_bases
GTGCATAGGACTGAGCCTACCATAAACTGCGTACATGACGGTACCCGATCCTTGCATCTGTCAATAGACACTACACGAGC
TCTGCCCGCGCACAGTGGGAACGAACCGACGCGTACGCACCTGGCAGCCGTTCGGGTAAGTCTGTTAAAAACTATACCTG
TGGCACCACCCAAGATATTGAAAGATTCCTCCTTCCGTGTCACACTGCGCATCGACCCTTCGGAGGAGTACTGTACCATG
CACCGTAGTAAGTCTTTGGCTTTTGTTGCGCTTTTTGCCGCACTCATTAGCTCGAGTGCGCTCGTTAGCATTCCTCTCAA
GCCTGTTCCGCTTGTACTGCAGAATGCAGCGGCCGTTCTCACCGGTTTATTGTTGGGACCGCGAGACGGTGCACTCGCCG
TTCTCAGCTTCCTCGGGGCAGGACTCCTTGGTCTGCCGGTTTTTTCAGGAGGTCGGGGCGGATACACCGCGCTTTTTGCC
CCTACGGGAGGATTCCTCCTTGGATACATACTCGCTGCTACGCTCGCTGGCGCAATCGCGCAGCACCACCGCCTGTCTTG
CACTCCACCACGCGGTGGTGGACGCGCACTCCTTCTTTGGATCAGACTTACCGTCGCAACGCTCGTTGGTTTTCTTTCGA
TTTACTCCATCGGTCTGCCGGTTCTCGGTTACGTGCTTGGCCTCAGGACCGGGGAGCTCATGCTAGGAGTCTTCCTTCCC
TTTTTTCTTGCCGACACCCTGAAAATCGCCCTTGTTGTCCTACTCGCCCATCATCTTGCCCCTACAGTTCGCCGCCATTT
GTACCGTCATGGTTGA

Upstream 100 bases:

>100_bases
AATCATTCCTAGGACGGGGCCCAATACCCTCGGTGCGAAACAAATCCAGACAATCGCGCACCACACGCACGAAGCGTGCG
ATACTCTCTCTGTCCCCAGC

Downstream 100 bases:

>100_bases
TGCCATAGTATTCGCGTGTCGCGGGTGTGTACGCGCCACAGGGCACGGTGCATCTTCTGTGGACGCATGAGCGCAGATGT
CGCGGCAGACACGGCTGTGG

Product: biotin synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MHRTEPTINCVHDGTRSLHLSIDTTRALPAHSGNEPTRTHLAAVRVSLLKTIPVAPPKILKDSSFRVTLRIDPSEEYCTM
HRSKSLAFVALFAALISSSALVSIPLKPVPLVLQNAAAVLTGLLLGPRDGALAVLSFLGAGLLGLPVFSGGRGGYTALFA
PTGGFLLGYILAATLAGAIAQHHRLSCTPPRGGGRALLLWIRLTVATLVGFLSIYSIGLPVLGYVLGLRTGELMLGVFLP
FFLADTLKIALVVLLAHHLAPTVRRHLYRHG

Sequences:

>Translated_271_residues
MHRTEPTINCVHDGTRSLHLSIDTTRALPAHSGNEPTRTHLAAVRVSLLKTIPVAPPKILKDSSFRVTLRIDPSEEYCTM
HRSKSLAFVALFAALISSSALVSIPLKPVPLVLQNAAAVLTGLLLGPRDGALAVLSFLGAGLLGLPVFSGGRGGYTALFA
PTGGFLLGYILAATLAGAIAQHHRLSCTPPRGGGRALLLWIRLTVATLVGFLSIYSIGLPVLGYVLGLRTGELMLGVFLP
FFLADTLKIALVVLLAHHLAPTVRRHLYRHG
>Mature_271_residues
MHRTEPTINCVHDGTRSLHLSIDTTRALPAHSGNEPTRTHLAAVRVSLLKTIPVAPPKILKDSSFRVTLRIDPSEEYCTM
HRSKSLAFVALFAALISSSALVSIPLKPVPLVLQNAAAVLTGLLLGPRDGALAVLSFLGAGLLGLPVFSGGRGGYTALFA
PTGGFLLGYILAATLAGAIAQHHRLSCTPPRGGGRALLLWIRLTVATLVGFLSIYSIGLPVLGYVLGLRTGELMLGVFLP
FFLADTLKIALVVLLAHHLAPTVRRHLYRHG

Specific function: Probable biotin transporter

COG id: COG1268

COG function: function code R; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BioY family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BIOY_TREPA (O83256)

Other databases:

- EMBL:   AE000520
- PIR:   B71351
- RefSeq:   NP_218668.1
- ProteinModelPortal:   O83256
- IntAct:   O83256
- GeneID:   2611584
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0228
- NMPDR:   fig|243276.1.peg.227
- TIGR:   TP_0228
- HOGENOM:   HBG731933
- OMA:   YPLLPAR
- ProtClustDB:   CLSK2300165
- BioCyc:   TPAL243276:TP_0228-MONOMER
- GO:   GO:0006810
- InterPro:   IPR003784

Pfam domain/function: PF02632 BioY

EC number: NA

Molecular weight: Translated: 28774; Mature: 28774

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f1a0894)-; HASH(0x20754784)-; HASH(0x1fdd065c)-; HASH(0xc893be8)-; HASH(0x2093ac90)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRTEPTINCVHDGTRSLHLSIDTTRALPAHSGNEPTRTHLAAVRVSLLKTIPVAPPKIL
CCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHC
KDSSFRVTLRIDPSEEYCTMHRSKSLAFVALFAALISSSALVSIPLKPVPLVLQNAAAVL
CCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
TGLLLGPRDGALAVLSFLGAGLLGLPVFSGGRGGYTALFAPTGGFLLGYILAATLAGAIA
HHHHCCCCCCHHHHHHHHCCCHHHCCEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
QHHRLSCTPPRGGGRALLLWIRLTVATLVGFLSIYSIGLPVLGYVLGLRTGELMLGVFLP
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FFLADTLKIALVVLLAHHLAPTVRRHLYRHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MHRTEPTINCVHDGTRSLHLSIDTTRALPAHSGNEPTRTHLAAVRVSLLKTIPVAPPKIL
CCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHC
KDSSFRVTLRIDPSEEYCTMHRSKSLAFVALFAALISSSALVSIPLKPVPLVLQNAAAVL
CCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
TGLLLGPRDGALAVLSFLGAGLLGLPVFSGGRGGYTALFAPTGGFLLGYILAATLAGAIA
HHHHCCCCCCHHHHHHHHCCCHHHCCEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
QHHRLSCTPPRGGGRALLLWIRLTVATLVGFLSIYSIGLPVLGYVLGLRTGELMLGVFLP
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FFLADTLKIALVVLLAHHLAPTVRRHLYRHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876