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The map label for this gene is fur [H]

Identifier: 188587457

GI number: 188587457

Start: 3098809

End: 3099258

Strand: Reverse

Name: fur [H]

Synonym: Nther_2867

Alternate gene names: 188587457

Gene position: 3099258-3098809 (Counterclockwise)

Preceding gene: 188587458

Following gene: 188587456

Centisome position: 97.91

GC content: 31.78

Gene sequence:

>450_bases
ATGAAAAAAGATGATCATAAACTAAAAGAGTACGAGCATAAATTTAAAGAACACAAACTGACCCCACAAAGAAAAGCTAT
TTTACAAGTTTTTCTAGAAAATCACGGAGGACATTTGAGTGCAGAAGAAATTCTTAAGTATGCCCAAGAAAAAAATAATG
ATATTGGTTTTGCAACGGTTTATCGTGCCCTAGATTTATTTGAAAAACTTAAAATAATAAATAGAGTTAACTTTGGTGAT
GGTAGAAGTAGATATGAACTAGTACAGCGGGAAATGAAACATCATCATCACCATTTAGTTTGTATGAATTGTCAGCGAAT
CATTGAAGTAATGGATTCTTTACTTCATGAGTTAGAAGAAAATATAGAAGAAGAGCATAACTTTAGCATTTATGATCATA
GACTTGAGTTTTATGGATATTGTGAGGATTGCCAAGAAGGGGAGGACTAA

Upstream 100 bases:

>100_bases
ATTCAACTAACTTAAGTGAAGCTATCTTTGGTGATGACTAAAAATTGATTTAGCAAATTACTTTGATTAATTTCTTATTG
ATTTTATTGGAGTGAGCCCC

Downstream 100 bases:

>100_bases
CAATTATGAAGTGGTCACCTAAATTTAATAAGCTAAAATCACAAAGATTAACAGCCCAACTGTGTACAGTACTTGTGATG
TTATTAATTTTGCAGCTTAT

Product: ferric uptake regulator, Fur family

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKKDDHKLKEYEHKFKEHKLTPQRKAILQVFLENHGGHLSAEEILKYAQEKNNDIGFATVYRALDLFEKLKIINRVNFGD
GRSRYELVQREMKHHHHHLVCMNCQRIIEVMDSLLHELEENIEEEHNFSIYDHRLEFYGYCEDCQEGED

Sequences:

>Translated_149_residues
MKKDDHKLKEYEHKFKEHKLTPQRKAILQVFLENHGGHLSAEEILKYAQEKNNDIGFATVYRALDLFEKLKIINRVNFGD
GRSRYELVQREMKHHHHHLVCMNCQRIIEVMDSLLHELEENIEEEHNFSIYDHRLEFYGYCEDCQEGED
>Mature_149_residues
MKKDDHKLKEYEHKFKEHKLTPQRKAILQVFLENHGGHLSAEEILKYAQEKNNDIGFATVYRALDLFEKLKIINRVNFGD
GRSRYELVQREMKHHHHHLVCMNCQRIIEVMDSLLHELEENIEEEHNFSIYDHRLEFYGYCEDCQEGED

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=132, Percent_Identity=38.6363636363636, Blast_Score=95, Evalue=2e-21,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17969; Mature: 17969

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKDDHKLKEYEHKFKEHKLTPQRKAILQVFLENHGGHLSAEEILKYAQEKNNDIGFATV
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHH
YRALDLFEKLKIINRVNFGDGRSRYELVQREMKHHHHHLVCMNCQRIIEVMDSLLHELEE
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIEEEHNFSIYDHRLEFYGYCEDCQEGED
HHHHHCCCHHHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure
MKKDDHKLKEYEHKFKEHKLTPQRKAILQVFLENHGGHLSAEEILKYAQEKNNDIGFATV
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHH
YRALDLFEKLKIINRVNFGDGRSRYELVQREMKHHHHHLVCMNCQRIIEVMDSLLHELEE
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIEEEHNFSIYDHRLEFYGYCEDCQEGED
HHHHHCCCHHHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]