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The map label for this gene is appB [H]

Identifier: 188587388

GI number: 188587388

Start: 3021724

End: 3022683

Strand: Reverse

Name: appB [H]

Synonym: Nther_2797

Alternate gene names: 188587388

Gene position: 3022683-3021724 (Counterclockwise)

Preceding gene: 188587389

Following gene: 188587387

Centisome position: 95.49

GC content: 38.02

Gene sequence:

>960_bases
ATGTATCAATATATAGTTAGAAGAATTCTTCAACTTATCCCTACAATTATTGGGGTTACTATAATTGTTTTTTTGGTAAT
CAATGCAGCCCCGGGTAATCCCATGAGCGGAATGGTAGACCCCAATTTGACTGAGGAAGAAATCGATCGTCAATTAGAAG
AAATGGGATTAAAAGATCCTATACACCAACGTTATTGGAGCTGGATTACGCAAGTAATCCAAGGAGATCTGGGATATTCA
TTCAGATATCATGTTCCGGTAGAAAGTTTGATTGGTTCCAGGATAGGTCCAACATTTATGCTTTCCTTTTCTGCCTTATT
CGTCAGTATTTTATTAGCGGTTCCGATAGGTGTGCTGTCTGCTACTAGGCAATATTCCAAAGTAGATAACTTGTTTACTG
TTATTGCAATTGGAGGAGTATCTATTCCCGTGTTTTTCCTGGGTATTTTGCTGATTAAATTCCTTGCCTTTGATTTTCAA
ATATTCCCAACAGGAGGTTATCCAAACCTGAGTGATGAAAATTTCTTTACTGCTATACCTAGAGTTTTGCATCATTTGAT
ACTTCCCATGATTGCTTTAGCTGCAGCCCAAACTGCTAGGTTTATGCGTTATACTAGATCCAGTATGCTAGAAGTTATTA
AACAGGATTATGTAAGAACTGCTAGGGCTAAAGGCTTATCAGAGAAAATAGTTATTTATAAACATGCCCTGCGTAATGCT
TTGATACCAGTCATCACACTCCTCGGTTTAACCCTTCCGTTCTTATTCTCCGGAGCTATATTAACAGAAACGGTCTTTGT
ATGGCCCGGTATGGGTAGATTATTGCTAGACTCTGTACATGACAGGGATTATCCTCTGTTAATGGGTATAAATCTGTTCT
TTGCCTTTATGGTAATGCTGGGTAATTTACTGGCAGATGTGTTATATGCCGTTGTTGATCCCCGCATTAAATATAATTAA

Upstream 100 bases:

>100_bases
TGACGTACATGAATGGTACCTTGAATAAGTCATAAAGGTGTGATGAGGGGCCCCACCCTTTTTTGGGGTGGGGATCCTTA
TTTACGAAAGGAGGCGTGGA

Downstream 100 bases:

>100_bases
TTTATTATAGAAGGGAGTGGATGGATTGAGTAATACTGCAACTTCTACTGCCCAAGAGAGGGTGGAACCCAAAGGGGTTA
TCACTCCAAGGCAGCTGGTT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MYQYIVRRILQLIPTIIGVTIIVFLVINAAPGNPMSGMVDPNLTEEEIDRQLEEMGLKDPIHQRYWSWITQVIQGDLGYS
FRYHVPVESLIGSRIGPTFMLSFSALFVSILLAVPIGVLSATRQYSKVDNLFTVIAIGGVSIPVFFLGILLIKFLAFDFQ
IFPTGGYPNLSDENFFTAIPRVLHHLILPMIALAAAQTARFMRYTRSSMLEVIKQDYVRTARAKGLSEKIVIYKHALRNA
LIPVITLLGLTLPFLFSGAILTETVFVWPGMGRLLLDSVHDRDYPLLMGINLFFAFMVMLGNLLADVLYAVVDPRIKYN

Sequences:

>Translated_319_residues
MYQYIVRRILQLIPTIIGVTIIVFLVINAAPGNPMSGMVDPNLTEEEIDRQLEEMGLKDPIHQRYWSWITQVIQGDLGYS
FRYHVPVESLIGSRIGPTFMLSFSALFVSILLAVPIGVLSATRQYSKVDNLFTVIAIGGVSIPVFFLGILLIKFLAFDFQ
IFPTGGYPNLSDENFFTAIPRVLHHLILPMIALAAAQTARFMRYTRSSMLEVIKQDYVRTARAKGLSEKIVIYKHALRNA
LIPVITLLGLTLPFLFSGAILTETVFVWPGMGRLLLDSVHDRDYPLLMGINLFFAFMVMLGNLLADVLYAVVDPRIKYN
>Mature_319_residues
MYQYIVRRILQLIPTIIGVTIIVFLVINAAPGNPMSGMVDPNLTEEEIDRQLEEMGLKDPIHQRYWSWITQVIQGDLGYS
FRYHVPVESLIGSRIGPTFMLSFSALFVSILLAVPIGVLSATRQYSKVDNLFTVIAIGGVSIPVFFLGILLIKFLAFDFQ
IFPTGGYPNLSDENFFTAIPRVLHHLILPMIALAAAQTARFMRYTRSSMLEVIKQDYVRTARAKGLSEKIVIYKHALRNA
LIPVITLLGLTLPFLFSGAILTETVFVWPGMGRLLLDSVHDRDYPLLMGINLFFAFMVMLGNLLADVLYAVVDPRIKYN

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=319, Percent_Identity=38.871473354232, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=39.3491124260355, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1787497, Length=319, Percent_Identity=35.1097178683386, Blast_Score=197, Evalue=5e-52,
Organism=Escherichia coli, GI1787761, Length=337, Percent_Identity=35.3115727002967, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1789888, Length=320, Percent_Identity=32.1875, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1788504, Length=362, Percent_Identity=29.5580110497238, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=30.8550185873606, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35890; Mature: 35890

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQYIVRRILQLIPTIIGVTIIVFLVINAAPGNPMSGMVDPNLTEEEIDRQLEEMGLKDP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCH
IHQRYWSWITQVIQGDLGYSFRYHVPVESLIGSRIGPTFMLSFSALFVSILLAVPIGVLS
HHHHHHHHHHHHHHHCCCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ATRQYSKVDNLFTVIAIGGVSIPVFFLGILLIKFLAFDFQIFPTGGYPNLSDENFFTAIP
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHH
RVLHHLILPMIALAAAQTARFMRYTRSSMLEVIKQDYVRTARAKGLSEKIVIYKHALRNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LIPVITLLGLTLPFLFSGAILTETVFVWPGMGRLLLDSVHDRDYPLLMGINLFFAFMVML
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GNLLADVLYAVVDPRIKYN
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYQYIVRRILQLIPTIIGVTIIVFLVINAAPGNPMSGMVDPNLTEEEIDRQLEEMGLKDP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCH
IHQRYWSWITQVIQGDLGYSFRYHVPVESLIGSRIGPTFMLSFSALFVSILLAVPIGVLS
HHHHHHHHHHHHHHHCCCCCEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ATRQYSKVDNLFTVIAIGGVSIPVFFLGILLIKFLAFDFQIFPTGGYPNLSDENFFTAIP
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHH
RVLHHLILPMIALAAAQTARFMRYTRSSMLEVIKQDYVRTARAKGLSEKIVIYKHALRNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LIPVITLLGLTLPFLFSGAILTETVFVWPGMGRLLLDSVHDRDYPLLMGINLFFAFMVML
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GNLLADVLYAVVDPRIKYN
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]