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The map label for this gene is nagB [H]

Identifier: 188587365

GI number: 188587365

Start: 2994437

End: 2995177

Strand: Reverse

Name: nagB [H]

Synonym: Nther_2772

Alternate gene names: 188587365

Gene position: 2995177-2994437 (Counterclockwise)

Preceding gene: 188587366

Following gene: 188587364

Centisome position: 94.62

GC content: 33.06

Gene sequence:

>741_bases
ATGAAATTAACTGTAGTGGATAACTATTTCCAATTAAGCCAAAAAGCAGCTGAAATCATAACAGATCAAATTATTTCAAA
ACCCAATACAATTTTGGGTTTGCCAACCGGAAGAACCCCTTTAGGTATGTATGAGTCACTGATCTCCAGGTATCAACAAG
GGCAACTTACTTTCAAAGATGTGACAACCTTTAATATTGATGAGTTTTTAGGTATATCTGAAGACAATCCTATTAGCTAT
CATTCTTACATGAACTATTATTTCTTTGACCACATTGATATTGATAAAGAGAATACTTTTCTTCCACCTAGTAATCCAGA
AGATCCAATAATAGCAGCAGCAAATTACGAACAAAAAGTCAAAGAAAATCCTGTAGATCTTATGATACTTGGTTTAGGTA
CTAATGGACATATCGGTTTTAATGAACCTGGAAACTCCCTCAGAGAAGACACTCATGTGACTGAATTATCGGATCAAACA
ATAATAAACAATAAAAAATTACTAAAAAAAACTTTAGGTAATGAATCCAAAGATGATTATGCCATTCCAGATAAGGCTAT
AACTATGGGAATAGGAACAATTTTAAGTGCCCAAAAACTCCTGATAATAGCTAATGGTAGTGAAAAAGCACCGGTGATCA
AGCAATTGTTCTCTCCTGAAATAACTACTAGATTACCAGCTAGTTTAGTCAAACTACATTCTAATGTAACTATAATTGTC
GATGGAGAGGCATATAATTAA

Upstream 100 bases:

>100_bases
AGAAGCGGGTGATGTATTGTTTAAAGCTAAAATCACAGGATAATACAGAAATATAATCTGTATTATTTGACTATAACTAC
CTCAACTGTGAGGTGTAAAC

Downstream 100 bases:

>100_bases
CTTGCTTTTTCTGGAATAACTGCTATAATTATTATTACAAGACCATATGGGAACATGGGATTACAAAATCTCAGCCCTGG
CCCAATGATGGCCAGGGTTT

Product: glucosamine-6-phosphate isomerase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKLTVVDNYFQLSQKAAEIITDQIISKPNTILGLPTGRTPLGMYESLISRYQQGQLTFKDVTTFNIDEFLGISEDNPISY
HSYMNYYFFDHIDIDKENTFLPPSNPEDPIIAAANYEQKVKENPVDLMILGLGTNGHIGFNEPGNSLREDTHVTELSDQT
IINNKKLLKKTLGNESKDDYAIPDKAITMGIGTILSAQKLLIIANGSEKAPVIKQLFSPEITTRLPASLVKLHSNVTIIV
DGEAYN

Sequences:

>Translated_246_residues
MKLTVVDNYFQLSQKAAEIITDQIISKPNTILGLPTGRTPLGMYESLISRYQQGQLTFKDVTTFNIDEFLGISEDNPISY
HSYMNYYFFDHIDIDKENTFLPPSNPEDPIIAAANYEQKVKENPVDLMILGLGTNGHIGFNEPGNSLREDTHVTELSDQT
IINNKKLLKKTLGNESKDDYAIPDKAITMGIGTILSAQKLLIIANGSEKAPVIKQLFSPEITTRLPASLVKLHSNVTIIV
DGEAYN
>Mature_246_residues
MKLTVVDNYFQLSQKAAEIITDQIISKPNTILGLPTGRTPLGMYESLISRYQQGQLTFKDVTTFNIDEFLGISEDNPISY
HSYMNYYFFDHIDIDKENTFLPPSNPEDPIIAAANYEQKVKENPVDLMILGLGTNGHIGFNEPGNSLREDTHVTELSDQT
IINNKKLLKKTLGNESKDDYAIPDKAITMGIGTILSAQKLLIIANGSEKAPVIKQLFSPEITTRLPASLVKLHSNVTIIV
DGEAYN

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI19923881, Length=250, Percent_Identity=38.4, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI13027378, Length=250, Percent_Identity=36.8, Blast_Score=169, Evalue=3e-42,
Organism=Escherichia coli, GI1786893, Length=247, Percent_Identity=33.6032388663968, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1789530, Length=250, Percent_Identity=30, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI48994958, Length=242, Percent_Identity=29.3388429752066, Blast_Score=88, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17554876, Length=253, Percent_Identity=35.9683794466403, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24581960, Length=250, Percent_Identity=32.8, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI19920764, Length=250, Percent_Identity=32.8, Blast_Score=158, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 27378; Mature: 27378

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTVVDNYFQLSQKAAEIITDQIISKPNTILGLPTGRTPLGMYESLISRYQQGQLTFKD
CEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCEEEEH
VTTFNIDEFLGISEDNPISYHSYMNYYFFDHIDIDKENTFLPPSNPEDPIIAAANYEQKV
EEEECHHHHCCCCCCCCEEHHHHEEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCHHHH
KENPVDLMILGLGTNGHIGFNEPGNSLREDTHVTELSDQTIINNKKLLKKTLGNESKDDY
HCCCCEEEEEEECCCCCCCCCCCCCHHHHCCCHHHCCCCHHHCCHHHHHHHHCCCCCCCC
AIPDKAITMGIGTILSAQKLLIIANGSEKAPVIKQLFSPEITTRLPASLVKLHSNVTIIV
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCEEEEE
DGEAYN
CCCCCC
>Mature Secondary Structure
MKLTVVDNYFQLSQKAAEIITDQIISKPNTILGLPTGRTPLGMYESLISRYQQGQLTFKD
CEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCEEEEH
VTTFNIDEFLGISEDNPISYHSYMNYYFFDHIDIDKENTFLPPSNPEDPIIAAANYEQKV
EEEECHHHHCCCCCCCCEEHHHHEEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCHHHH
KENPVDLMILGLGTNGHIGFNEPGNSLREDTHVTELSDQTIINNKKLLKKTLGNESKDDY
HCCCCEEEEEEECCCCCCCCCCCCCHHHHCCCHHHCCCCHHHCCHHHHHHHHCCCCCCCC
AIPDKAITMGIGTILSAQKLLIIANGSEKAPVIKQLFSPEITTRLPASLVKLHSNVTIIV
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCEEEEE
DGEAYN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA