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The map label for this gene is hbpA [H]

Identifier: 188587351

GI number: 188587351

Start: 2978120

End: 2979694

Strand: Reverse

Name: hbpA [H]

Synonym: Nther_2758

Alternate gene names: 188587351

Gene position: 2979694-2978120 (Counterclockwise)

Preceding gene: 188587353

Following gene: 188587350

Centisome position: 94.13

GC content: 38.98

Gene sequence:

>1575_bases
TTGTTTAGAAAAAGGTTGTTGACAATATTAACTTGTATACTAATCTTTTCCCTAACCATTGTCACTGCTTGCTCATCTGA
TGAAGAAGCGGGCGACACTGGTCCTGCTGAATCCACTGATGAACTGGTTTGGGGAATTACTGAAGAAGCCGATACCCTTG
ACCCTAGAGCTACAGTTTCTACATATTCTGTAGAAGTTTTTGAAATGGTTTTTAATTCACTGGTTTACCCAGATGGTGAT
TTGGAAATCCAAAAAGATCTGGCAACTGATATTGAAGTCAAGGATGACGATGTCACTTATGTTTTTGAATTAAGAGACGA
TGTCACATGGCATGACGGAGAACCTTTAACTGCTCATGATGTGGAGTTTACCTATGAAACCATTTTAGATCCAGAATTTG
GATCACCTCATAAAGAGCGAATTGATTACATTAAGAGGGTAGAAGCAATAGATGATTATACCGTTGAATTTGAAACTGAA
GACCCCCATGCTGCTTTTTTACACGATCTAGATAGATTCATTGTTCCAAAACATGCAGCTCCTAGAAACCCTTTTGAGGA
TGTGGATGAAGTAGAAGAAGAAAAAGAGGGAGAAGACGTTTTTGCCTATGAACCTATCGGTTCAGGTCCTTTTAAAGTAG
TTGAATGGAGACCTAATGATACACTGACCTTAGAACGGTATGAGGATTATCATGAAGGCCCGGCTGAACTGAAGAAGATT
ATTAGACGCGAAATACCAGAAGTGGAAGCGATATATGCGGACTTAATGGCTGGTGATATTGATAAAGGGATAGTGCCTGA
CCAAGAAATTGATGATATTGATGAAAATCCCGATTATACTTTGATACAGGAACGAACCTTAAATTACTTTCCGATTTTTA
TCAATCACGGCTACGACGGTCATGATAAATTAAGCCAATTAGAAGTGCGTCGTGCATTAAATAAGGCTGCTGATTACGAT
CAAATAGTTGAACACATTTTCCCTACTTCATACAGGGCTCATACTCCCATCATAGAAGGGACTTGGGCCCATGACCCTGA
TGCAGTTCGAGTTTATGAACATGACCCAGAGAAAGCTAGAGAACTACTAGAAGAAGCAGGTTACGAAGAGGGTATTGAAT
TAGAATTGATCATGAGTGATTCTAACACCAATATGGAGTTTGGTGAAATGTTAAGTGCACAATTTGAAGAAGCCGGCATT
GACTTAGATGTCAATACCATGGACTTTGGTGCCATGTTGGACCGTACTCTTGATGGTGATTATCAGCTTAGTTCAGTTGG
GATGACTAATATGACAGATCCTGATGAATTTATGCAGCGATATGTAGATGGAGGTGGGGCTTCCAATTATGAAAATCCCG
AAATGGATGAGTTGATTATAGAAGCTAGAAGGACCGTGGATGATCAAGAAAAAAGAGCAGAACTGTACTCAGAAATTCAA
GAGATTTTTAGTGAAGAGGCGGTTGATATTCCCATCAGAAATAGTACAATACTTGTAGTTTGGAATTCTGATTTTAATAT
GGACTACAACTATATTGAGCGATATCGTAATATGAAGGATGCTTACTGGGATTAA

Upstream 100 bases:

>100_bases
TGTGACCTGGAGGTGGTCCATCAATAAAAATATGTACTATTATAAAGTAAATTATCCGCAATACAAAACCCAAATAAAAT
ATTTTCGAGGGGGAATGAAT

Downstream 100 bases:

>100_bases
GAATAATTATGAGACCTGATATCTAAGACAAATGAGTTATACAAAATAAAACTTGTAGGTATTACCAGTTCCCAATTAGG
GGCGGGGCTTAACTCCCCCG

Product: extracellular solute-binding protein family 5

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MFRKRLLTILTCILIFSLTIVTACSSDEEAGDTGPAESTDELVWGITEEADTLDPRATVSTYSVEVFEMVFNSLVYPDGD
LEIQKDLATDIEVKDDDVTYVFELRDDVTWHDGEPLTAHDVEFTYETILDPEFGSPHKERIDYIKRVEAIDDYTVEFETE
DPHAAFLHDLDRFIVPKHAAPRNPFEDVDEVEEEKEGEDVFAYEPIGSGPFKVVEWRPNDTLTLERYEDYHEGPAELKKI
IRREIPEVEAIYADLMAGDIDKGIVPDQEIDDIDENPDYTLIQERTLNYFPIFINHGYDGHDKLSQLEVRRALNKAADYD
QIVEHIFPTSYRAHTPIIEGTWAHDPDAVRVYEHDPEKARELLEEAGYEEGIELELIMSDSNTNMEFGEMLSAQFEEAGI
DLDVNTMDFGAMLDRTLDGDYQLSSVGMTNMTDPDEFMQRYVDGGGASNYENPEMDELIIEARRTVDDQEKRAELYSEIQ
EIFSEEAVDIPIRNSTILVVWNSDFNMDYNYIERYRNMKDAYWD

Sequences:

>Translated_524_residues
MFRKRLLTILTCILIFSLTIVTACSSDEEAGDTGPAESTDELVWGITEEADTLDPRATVSTYSVEVFEMVFNSLVYPDGD
LEIQKDLATDIEVKDDDVTYVFELRDDVTWHDGEPLTAHDVEFTYETILDPEFGSPHKERIDYIKRVEAIDDYTVEFETE
DPHAAFLHDLDRFIVPKHAAPRNPFEDVDEVEEEKEGEDVFAYEPIGSGPFKVVEWRPNDTLTLERYEDYHEGPAELKKI
IRREIPEVEAIYADLMAGDIDKGIVPDQEIDDIDENPDYTLIQERTLNYFPIFINHGYDGHDKLSQLEVRRALNKAADYD
QIVEHIFPTSYRAHTPIIEGTWAHDPDAVRVYEHDPEKARELLEEAGYEEGIELELIMSDSNTNMEFGEMLSAQFEEAGI
DLDVNTMDFGAMLDRTLDGDYQLSSVGMTNMTDPDEFMQRYVDGGGASNYENPEMDELIIEARRTVDDQEKRAELYSEIQ
EIFSEEAVDIPIRNSTILVVWNSDFNMDYNYIERYRNMKDAYWD
>Mature_524_residues
MFRKRLLTILTCILIFSLTIVTACSSDEEAGDTGPAESTDELVWGITEEADTLDPRATVSTYSVEVFEMVFNSLVYPDGD
LEIQKDLATDIEVKDDDVTYVFELRDDVTWHDGEPLTAHDVEFTYETILDPEFGSPHKERIDYIKRVEAIDDYTVEFETE
DPHAAFLHDLDRFIVPKHAAPRNPFEDVDEVEEEKEGEDVFAYEPIGSGPFKVVEWRPNDTLTLERYEDYHEGPAELKKI
IRREIPEVEAIYADLMAGDIDKGIVPDQEIDDIDENPDYTLIQERTLNYFPIFINHGYDGHDKLSQLEVRRALNKAADYD
QIVEHIFPTSYRAHTPIIEGTWAHDPDAVRVYEHDPEKARELLEEAGYEEGIELELIMSDSNTNMEFGEMLSAQFEEAGI
DLDVNTMDFGAMLDRTLDGDYQLSSVGMTNMTDPDEFMQRYVDGGGASNYENPEMDELIIEARRTVDDQEKRAELYSEIQ
EIFSEEAVDIPIRNSTILVVWNSDFNMDYNYIERYRNMKDAYWD

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=473, Percent_Identity=27.2727272727273, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1787762, Length=468, Percent_Identity=26.4957264957265, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787052, Length=484, Percent_Identity=24.3801652892562, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787551, Length=542, Percent_Identity=23.6162361623616, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789397, Length=480, Percent_Identity=24.375, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789887, Length=466, Percent_Identity=23.6051502145923, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI87081878, Length=530, Percent_Identity=22.4528301886792, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787495, Length=529, Percent_Identity=21.9281663516068, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60419; Mature: 60419

Theoretical pI: Translated: 3.88; Mature: 3.88

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRKRLLTILTCILIFSLTIVTACSSDEEAGDTGPAESTDELVWGITEEADTLDPRATVS
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHEEECCCCCCCCCCCCEEH
TYSVEVFEMVFNSLVYPDGDLEIQKDLATDIEVKDDDVTYVFELRDDVTWHDGEPLTAHD
HHHHHHHHHHHHHHCCCCCCCEEHHHCCCCCEECCCCEEEEEEECCCCCCCCCCCCEECC
VEFTYETILDPEFGSPHKERIDYIKRVEAIDDYTVEFETEDPHAAFLHDLDRFIVPKHAA
CCEEHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCC
PRNPFEDVDEVEEEKEGEDVFAYEPIGSGPFKVVEWRPNDTLTLERYEDYHEGPAELKKI
CCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCEEEHHHHCCCCCHHHHHHH
IRREIPEVEAIYADLMAGDIDKGIVPDQEIDDIDENPDYTLIQERTLNYFPIFINHGYDG
HHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCC
HDKLSQLEVRRALNKAADYDQIVEHIFPTSYRAHTPIIEGTWAHDPDAVRVYEHDPEKAR
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEEEECCHHHHH
ELLEEAGYEEGIELELIMSDSNTNMEFGEMLSAQFEEAGIDLDVNTMDFGAMLDRTLDGD
HHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCC
YQLSSVGMTNMTDPDEFMQRYVDGGGASNYENPEMDELIIEARRTVDDQEKRAELYSEIQ
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
EIFSEEAVDIPIRNSTILVVWNSDFNMDYNYIERYRNMKDAYWD
HHHHCCCEECEECCCEEEEEECCCCCCCHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MFRKRLLTILTCILIFSLTIVTACSSDEEAGDTGPAESTDELVWGITEEADTLDPRATVS
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHEEECCCCCCCCCCCCEEH
TYSVEVFEMVFNSLVYPDGDLEIQKDLATDIEVKDDDVTYVFELRDDVTWHDGEPLTAHD
HHHHHHHHHHHHHHCCCCCCCEEHHHCCCCCEECCCCEEEEEEECCCCCCCCCCCCEECC
VEFTYETILDPEFGSPHKERIDYIKRVEAIDDYTVEFETEDPHAAFLHDLDRFIVPKHAA
CCEEHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCC
PRNPFEDVDEVEEEKEGEDVFAYEPIGSGPFKVVEWRPNDTLTLERYEDYHEGPAELKKI
CCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCEEEHHHHCCCCCHHHHHHH
IRREIPEVEAIYADLMAGDIDKGIVPDQEIDDIDENPDYTLIQERTLNYFPIFINHGYDG
HHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCC
HDKLSQLEVRRALNKAADYDQIVEHIFPTSYRAHTPIIEGTWAHDPDAVRVYEHDPEKAR
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEEEECCHHHHH
ELLEEAGYEEGIELELIMSDSNTNMEFGEMLSAQFEEAGIDLDVNTMDFGAMLDRTLDGD
HHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCC
YQLSSVGMTNMTDPDEFMQRYVDGGGASNYENPEMDELIIEARRTVDDQEKRAELYSEIQ
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
EIFSEEAVDIPIRNSTILVVWNSDFNMDYNYIERYRNMKDAYWD
HHHHCCCEECEECCCEEEEEECCCCCCCHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]