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The map label for this gene is fabH [H]

Identifier: 188587338

GI number: 188587338

Start: 2962589

End: 2963620

Strand: Reverse

Name: fabH [H]

Synonym: Nther_2744

Alternate gene names: 188587338

Gene position: 2963620-2962589 (Counterclockwise)

Preceding gene: 188587340

Following gene: 188587337

Centisome position: 93.62

GC content: 39.15

Gene sequence:

>1032_bases
GTGTCAGATCAACAGATGAACAGAAACAGTATAGGTATCGTTTCCCTGGCTACGTATATACCCGATAATTTTATGACTAG
TCAGGAATTGGCAAATAAAAGCGGCGTTCCTCAGGATGTAATCGAGGACAAAATGGGAATTAAACAGAAACCAATCCCCG
GAAAAGAAGACCACACCTGTGAAATGGGCATCAAGGCTGCCAATAGGGCAATTGAAAAAGGAGAAATAGATCCCGAGAAC
ATTGATCTGGTCATCTATATTGGAGAAGAACATAAAGAATGGTTGCTATGGACTGCCGGGATAAAACTACAGTATGAAAT
CGGGGCCGAAAATGCCTGGGCTTTTGATATAAGTCAACGTTGTGGGACTGGGGTAGTTGGAATCGAGATAGCTAAGTCTT
TAATGATGGCTAATCCAGATATTAATACAGTGTTGTTGGCTGGTGGTTATAGGAACTGTGATTTTATTGACTATGAAAAT
CCACGAGTACGGTTTATGTATAATCTAGGATCTGGTGGAGGCGCCATGATTTTGCAAAAAGGATTAAACAAAAATAAAGT
GCTCGAAAGCTCAATTATAACCGATGGTTCTCTATCTGAAGATGTAATAGTACCGGCAGGAGGTACTAAACAACCAATTA
GCAGTGAAGCCATCAAGAATAAAGAAAATTACTTAGATGTGACGGATCCTGAGGGTATGAAGGAGCGATTAGATGAAGTA
TCAATTAAGAACTTCTTTAAAGTGATTGAAACCGCTGTAGAAAAAAGTGGATATAGCACTAGTGATATCGATTATCTAGC
CCTTCTTCATATGAAAAAATCAGCTCACAAAGGTGTTCTGGAAGAACTGAATCTTTCTGAAAAACAATCTATTTATCTTG
AAGAATACGGCCATTTAGGTCAATTCGATCAAATTTTATCAACTGAGCTCGCCCTGGAACAGGGAAAAATTACAGATGGT
GATTTAGTGGTGTGGGTAAGTGCAGGCATAGGTTATGCCTGGAATGCCTCTGTTATTAAATGGGGTAATTAA

Upstream 100 bases:

>100_bases
GGTTTTGCCTGTTCTTATAGGTAGAATAAAAAATGGCATGAAAATTGCAAATTTTTAAACATAAATTGTTATAGTTATAT
AAATTTCGGAGGTGGCTGCA

Downstream 100 bases:

>100_bases
AGAAGGATATGTTACTTTAATCTAGCCTGGGCTTAATAGATTTTTTAATTGAATCTTATCAAAGTTAACTTTTGGGAGGG
ACTAAAATGCGTCTCAAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSDQQMNRNSIGIVSLATYIPDNFMTSQELANKSGVPQDVIEDKMGIKQKPIPGKEDHTCEMGIKAANRAIEKGEIDPEN
IDLVIYIGEEHKEWLLWTAGIKLQYEIGAENAWAFDISQRCGTGVVGIEIAKSLMMANPDINTVLLAGGYRNCDFIDYEN
PRVRFMYNLGSGGGAMILQKGLNKNKVLESSIITDGSLSEDVIVPAGGTKQPISSEAIKNKENYLDVTDPEGMKERLDEV
SIKNFFKVIETAVEKSGYSTSDIDYLALLHMKKSAHKGVLEELNLSEKQSIYLEEYGHLGQFDQILSTELALEQGKITDG
DLVVWVSAGIGYAWNASVIKWGN

Sequences:

>Translated_343_residues
MSDQQMNRNSIGIVSLATYIPDNFMTSQELANKSGVPQDVIEDKMGIKQKPIPGKEDHTCEMGIKAANRAIEKGEIDPEN
IDLVIYIGEEHKEWLLWTAGIKLQYEIGAENAWAFDISQRCGTGVVGIEIAKSLMMANPDINTVLLAGGYRNCDFIDYEN
PRVRFMYNLGSGGGAMILQKGLNKNKVLESSIITDGSLSEDVIVPAGGTKQPISSEAIKNKENYLDVTDPEGMKERLDEV
SIKNFFKVIETAVEKSGYSTSDIDYLALLHMKKSAHKGVLEELNLSEKQSIYLEEYGHLGQFDQILSTELALEQGKITDG
DLVVWVSAGIGYAWNASVIKWGN
>Mature_342_residues
SDQQMNRNSIGIVSLATYIPDNFMTSQELANKSGVPQDVIEDKMGIKQKPIPGKEDHTCEMGIKAANRAIEKGEIDPENI
DLVIYIGEEHKEWLLWTAGIKLQYEIGAENAWAFDISQRCGTGVVGIEIAKSLMMANPDINTVLLAGGYRNCDFIDYENP
RVRFMYNLGSGGGAMILQKGLNKNKVLESSIITDGSLSEDVIVPAGGTKQPISSEAIKNKENYLDVTDPEGMKERLDEVS
IKNFFKVIETAVEKSGYSTSDIDYLALLHMKKSAHKGVLEELNLSEKQSIYLEEYGHLGQFDQILSTELALEQGKITDGD
LVVWVSAGIGYAWNASVIKWGN

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=333, Percent_Identity=19.5195195195195, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37876; Mature: 37745

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00098 THIOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQQMNRNSIGIVSLATYIPDNFMTSQELANKSGVPQDVIEDKMGIKQKPIPGKEDHTC
CCCCCCCCCCCEEEEEHHHCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHH
EMGIKAANRAIEKGEIDPENIDLVIYIGEEHKEWLLWTAGIKLQYEIGAENAWAFDISQR
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEECEEEEEEECCCCEEEEECHHH
CGTGVVGIEIAKSLMMANPDINTVLLAGGYRNCDFIDYENPRVRFMYNLGSGGGAMILQK
CCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCEEEEEEEECCCCCCHHEEC
GLNKNKVLESSIITDGSLSEDVIVPAGGTKQPISSEAIKNKENYLDVTDPEGMKERLDEV
CCCCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHCCCCCEEECCCCCHHHHHHHHH
SIKNFFKVIETAVEKSGYSTSDIDYLALLHMKKSAHKGVLEELNLSEKQSIYLEEYGHLG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHCCCC
QFDQILSTELALEQGKITDGDLVVWVSAGIGYAWNASVIKWGN
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCEEECCC
>Mature Secondary Structure 
SDQQMNRNSIGIVSLATYIPDNFMTSQELANKSGVPQDVIEDKMGIKQKPIPGKEDHTC
CCCCCCCCCCEEEEEHHHCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHH
EMGIKAANRAIEKGEIDPENIDLVIYIGEEHKEWLLWTAGIKLQYEIGAENAWAFDISQR
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEECEEEEEEECCCCEEEEECHHH
CGTGVVGIEIAKSLMMANPDINTVLLAGGYRNCDFIDYENPRVRFMYNLGSGGGAMILQK
CCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCEEEEEEEECCCCCCHHEEC
GLNKNKVLESSIITDGSLSEDVIVPAGGTKQPISSEAIKNKENYLDVTDPEGMKERLDEV
CCCCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHCCCCCEEECCCCCHHHHHHHHH
SIKNFFKVIETAVEKSGYSTSDIDYLALLHMKKSAHKGVLEELNLSEKQSIYLEEYGHLG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHCCCC
QFDQILSTELALEQGKITDGDLVVWVSAGIGYAWNASVIKWGN
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]