Click here to switch to the map view.

The map label for this gene is yqiR [H]

Identifier: 188587335

GI number: 188587335

Start: 2958874

End: 2960289

Strand: Reverse

Name: yqiR [H]

Synonym: Nther_2741

Alternate gene names: 188587335

Gene position: 2960289-2958874 (Counterclockwise)

Preceding gene: 188587336

Following gene: 188587334

Centisome position: 93.52

GC content: 38.14

Gene sequence:

>1416_bases
GTGAGCACAATACTCAAAAATTTTGAAAATGTAGTTGATGTAGTAGACAGGATTTTTGATGTGATTCCCGTGCCAGTGAT
CCTTGTGGACGAAAAAGGGATTATTCGAATGATAAACAGAGCCTTTGCTGATCTATTGAAAGTTTCAAAACAGCAGGCCA
TAGGTCGCCCGGCTGTGGAGGTCGATCATAATAGCAAATGGCCCGTTGTGCTTAAATCCGGTGAATTTGATATAGCTAAA
AAACATAAATTCGCAAGAACAGGAGAAGATGCCGTCGTTCACAGAATACCAATTTACGATTATGACAGTGGTGAAATTGT
CGGCGGTTTCGGCATGGTTCTGTTTCAAAATTTGAAAGAGTTAAGGGACTTGGCAGATAAAAATAAGCTCTTGGAAAAGA
AACTAGACCACTACAAACAAAGAGTGCGCCAAATTTATAGTACTAAGTATTCTTGGGATAATATCAAAACCTGTTCCTCT
AAAATGGAAGCATGTAAACAAAATGCTAAAAAAGCAGCGCGAACTGATTTAAATGTACTTATAACGGGTGAAAGTGGAGT
GGGCAAAGAAATCTTTGCCCAGGCCATTCACAATGAAAGTCATCGTTCTGATCATCCTTTTATCAAAGTAAACTGTGCTG
CTATACCAGAAAATTTACTGGAATCCGAGCTATTTGGTTATCAAGGTGGGGCTTTTACAGGCGCCTCTAAAGAAGGAAAA
CCAGGTAAATTTGAACTTGCCGACAAAGGCACCCTGTTTTTTGATGAAATTGGTGATATGCCGAAAAAAATGCAGGCCAA
GCTCTTGCGAGTTATTCAAGAAGGGGAGGTAGAGCGACTGGGAGGCCAAAAAGAACAGGAAGTTGATGTCAGGATTATAG
CTGCAACCAATAAGAATTTAGAAGAGTTAGTTGCAACTGATGATTTTAGAGAGGACCTGTTTTATCGGATAAATGTCTTG
ACTTTGAATATACCGCCTCTTAAAGATCGAAAAGAAGATATAGCACTACTGGCAGAAGATTTTCTATACGAAACTAAACA
AGAAATGGGAGAGAATAAACAAATTTCTCAAGAAGCAGTTGAGGTACTTCAAAAATATGATTGGCCGGGTAATATCAGGC
AACTGAAAAATATTATTCAGCGCTTGGCAGTCAATGCTGAAACCACTGTAATTGAGAAGAGCGATATACCCATAAAACTT
CTAAAACAATTGCAAATTAGCGAATCTCCAAGTTATCCGGAAGAAGGATTAAATGAAATAGTAGAACAGGTGGAAAAAAA
GGTTATCAGAGAAACACTAGAACTTTATGATTTCAATAAATCCATGGCAGCTAGTATATTGAATATACCCAGGTCTACAC
TGTATCGAAAAATGAAAAAATACGGACTCAAGGAGGGTATTTATGGTTCGGATTAA

Upstream 100 bases:

>100_bases
TTAACAACTAAAAAACAAGTGCAGGATTAAACTGGTTATTGTCGAAATTTTCTCACAGAATGTAGCGTATTGCTACAAAT
CTGTGGGGGGAGGTCTGCTT

Downstream 100 bases:

>100_bases
CATTGATTCTGTGGAAATACCCAGGGGGGAGACAATTTATTACCGCTGGCGTGAAGGGTCTAGCTCTAGTTATCCTTTGG
TTTTGGTTCATGGAAATATG

Product: PAS modulated sigma54 specific transcriptional regulator, Fis family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSTILKNFENVVDVVDRIFDVIPVPVILVDEKGIIRMINRAFADLLKVSKQQAIGRPAVEVDHNSKWPVVLKSGEFDIAK
KHKFARTGEDAVVHRIPIYDYDSGEIVGGFGMVLFQNLKELRDLADKNKLLEKKLDHYKQRVRQIYSTKYSWDNIKTCSS
KMEACKQNAKKAARTDLNVLITGESGVGKEIFAQAIHNESHRSDHPFIKVNCAAIPENLLESELFGYQGGAFTGASKEGK
PGKFELADKGTLFFDEIGDMPKKMQAKLLRVIQEGEVERLGGQKEQEVDVRIIAATNKNLEELVATDDFREDLFYRINVL
TLNIPPLKDRKEDIALLAEDFLYETKQEMGENKQISQEAVEVLQKYDWPGNIRQLKNIIQRLAVNAETTVIEKSDIPIKL
LKQLQISESPSYPEEGLNEIVEQVEKKVIRETLELYDFNKSMAASILNIPRSTLYRKMKKYGLKEGIYGSD

Sequences:

>Translated_471_residues
MSTILKNFENVVDVVDRIFDVIPVPVILVDEKGIIRMINRAFADLLKVSKQQAIGRPAVEVDHNSKWPVVLKSGEFDIAK
KHKFARTGEDAVVHRIPIYDYDSGEIVGGFGMVLFQNLKELRDLADKNKLLEKKLDHYKQRVRQIYSTKYSWDNIKTCSS
KMEACKQNAKKAARTDLNVLITGESGVGKEIFAQAIHNESHRSDHPFIKVNCAAIPENLLESELFGYQGGAFTGASKEGK
PGKFELADKGTLFFDEIGDMPKKMQAKLLRVIQEGEVERLGGQKEQEVDVRIIAATNKNLEELVATDDFREDLFYRINVL
TLNIPPLKDRKEDIALLAEDFLYETKQEMGENKQISQEAVEVLQKYDWPGNIRQLKNIIQRLAVNAETTVIEKSDIPIKL
LKQLQISESPSYPEEGLNEIVEQVEKKVIRETLELYDFNKSMAASILNIPRSTLYRKMKKYGLKEGIYGSD
>Mature_470_residues
STILKNFENVVDVVDRIFDVIPVPVILVDEKGIIRMINRAFADLLKVSKQQAIGRPAVEVDHNSKWPVVLKSGEFDIAKK
HKFARTGEDAVVHRIPIYDYDSGEIVGGFGMVLFQNLKELRDLADKNKLLEKKLDHYKQRVRQIYSTKYSWDNIKTCSSK
MEACKQNAKKAARTDLNVLITGESGVGKEIFAQAIHNESHRSDHPFIKVNCAAIPENLLESELFGYQGGAFTGASKEGKP
GKFELADKGTLFFDEIGDMPKKMQAKLLRVIQEGEVERLGGQKEQEVDVRIIAATNKNLEELVATDDFREDLFYRINVLT
LNIPPLKDRKEDIALLAEDFLYETKQEMGENKQISQEAVEVLQKYDWPGNIRQLKNIIQRLAVNAETTVIEKSDIPIKLL
KQLQISESPSYPEEGLNEIVEQVEKKVIRETLELYDFNKSMAASILNIPRSTLYRKMKKYGLKEGIYGSD

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=406, Percent_Identity=41.6256157635468, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1789233, Length=312, Percent_Identity=45.1923076923077, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI87082117, Length=322, Percent_Identity=44.0993788819876, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1789087, Length=363, Percent_Identity=39.9449035812672, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1786524, Length=393, Percent_Identity=37.9134860050891, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI1790299, Length=388, Percent_Identity=38.9175257731959, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1788905, Length=340, Percent_Identity=40.5882352941176, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI87082152, Length=316, Percent_Identity=40.8227848101266, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1790437, Length=339, Percent_Identity=40.7079646017699, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1787583, Length=446, Percent_Identity=33.4080717488789, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI87081872, Length=319, Percent_Identity=39.1849529780564, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87081858, Length=451, Percent_Identity=28.6031042128603, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789828, Length=238, Percent_Identity=33.6134453781513, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53552; Mature: 53421

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTILKNFENVVDVVDRIFDVIPVPVILVDEKGIIRMINRAFADLLKVSKQQAIGRPAVE
CCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VDHNSKWPVVLKSGEFDIAKKHKFARTGEDAVVHRIPIYDYDSGEIVGGFGMVLFQNLKE
ECCCCCCCEEEECCCCCHHHHHHHHCCCCCCEEEEECEEECCCCCEEHHHHHHHHHHHHH
LRDLADKNKLLEKKLDHYKQRVRQIYSTKYSWDNIKTCSSKMEACKQNAKKAARTDLNVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEE
ITGESGVGKEIFAQAIHNESHRSDHPFIKVNCAAIPENLLESELFGYQGGAFTGASKEGK
EECCCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHHCCCCCCCCCCCCCCC
PGKFELADKGTLFFDEIGDMPKKMQAKLLRVIQEGEVERLGGQKEQEVDVRIIAATNKNL
CCCEEECCCCCEEHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEEECCCCH
EELVATDDFREDLFYRINVLTLNIPPLKDRKEDIALLAEDFLYETKQEMGENKQISQEAV
HHHHHCCHHHHHHEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EVLQKYDWPGNIRQLKNIIQRLAVNAETTVIEKSDIPIKLLKQLQISESPSYPEEGLNEI
HHHHHCCCCCCHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHH
VEQVEKKVIRETLELYDFNKSMAASILNIPRSTLYRKMKKYGLKEGIYGSD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
STILKNFENVVDVVDRIFDVIPVPVILVDEKGIIRMINRAFADLLKVSKQQAIGRPAVE
CHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VDHNSKWPVVLKSGEFDIAKKHKFARTGEDAVVHRIPIYDYDSGEIVGGFGMVLFQNLKE
ECCCCCCCEEEECCCCCHHHHHHHHCCCCCCEEEEECEEECCCCCEEHHHHHHHHHHHHH
LRDLADKNKLLEKKLDHYKQRVRQIYSTKYSWDNIKTCSSKMEACKQNAKKAARTDLNVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEE
ITGESGVGKEIFAQAIHNESHRSDHPFIKVNCAAIPENLLESELFGYQGGAFTGASKEGK
EECCCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHHCCCCCCCCCCCCCCC
PGKFELADKGTLFFDEIGDMPKKMQAKLLRVIQEGEVERLGGQKEQEVDVRIIAATNKNL
CCCEEECCCCCEEHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEEECCCCH
EELVATDDFREDLFYRINVLTLNIPPLKDRKEDIALLAEDFLYETKQEMGENKQISQEAV
HHHHHCCHHHHHHEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EVLQKYDWPGNIRQLKNIIQRLAVNAETTVIEKSDIPIKLLKQLQISESPSYPEEGLNEI
HHHHHCCCCCCHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHH
VEQVEKKVIRETLELYDFNKSMAASILNIPRSTLYRKMKKYGLKEGIYGSD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]