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The map label for this gene is sppA [H]

Identifier: 188587314

GI number: 188587314

Start: 2934522

End: 2935499

Strand: Reverse

Name: sppA [H]

Synonym: Nther_2718

Alternate gene names: 188587314

Gene position: 2935499-2934522 (Counterclockwise)

Preceding gene: 188587316

Following gene: 188587313

Centisome position: 92.73

GC content: 41.31

Gene sequence:

>978_bases
TTGAATGAAGCTGAGAAAAGTTCTTTAAAGTTATTTGTGTTGAAAGCTCTAATAGTTGTGGGTGGTATAGCAGCTTTTTT
TATAATAGCTCTCTCGTCTTTTTTTCTCTTGGGAGGAGCTTTTATTTCACTGCTGGATGCTGACCCTGTGGAAGAAGATG
ACCTGGTTTATGTGATTGATTTGGAAGGCGAAATTTCCGAAGCAGCAGGGCCCGGTCCAGGAGGTTTAGGTATTTCTCCT
AGAATTGTCCAGGAAAGTCTGGATAAAGCCAAAGCTGATAACGCTGAAGCAGTAGTGTTGAGAGTTAATTCCCCCGGCGG
AACGGTAGCAGCATCCCAGGAAATAGCTTCAATCATTGATGATTTTGAACTGCCCACAGTAGTATCTATGGCCGATTCGG
CTACTTCAGGTGGTTATTATATCTCTGCCGCAGCTGACAGGATAAAAGCCCAGGATACTAGCACCACCGGTTCAATTGGT
GTGATTAGTGTTATGTATAATTTCCAGGAATTATATGACAATTTGGGAATTGAAGTTGAGGTAATAAAAACAGGTGAATA
CAAAGATATGGGTTTTGAAACCATGACAGAAGAGGAACGTCAAATAATTCAAGACCTATCTGATGAAATGTATGAACACT
TTGTAGCAGAAGTTTCGGATTACAGAGATATGGATAAAGAAGATGTTTATGAGGTGGCTACTGGCGAAATAATGACTGGA
ACAGCGGCTTATGAACAGGGACTTGTTGATGGTTTAGGCGGTATAGACAGGGCAGTAGACAAAGCTGGTGAACTGGCAGG
CATTGAAGACCCTAATACCAGATGGTTAGAACCCGAAGGCTTGTTTGATCAGCTGTTTTTCCCCATGGTTCAGGAAAGTG
ACTTATTAGAATTAGATTCCCTTTCGGAAGAAACTGAGCAAATCGATAAGGCTAGAAACCTTCCGTCTGTGGAATTTCGC
TATCAAAGTAATTTTTAA

Upstream 100 bases:

>100_bases
AATATTTAGTTGGGTTACAATTTATGATAGAGATTATAATTGTTCTCTATAGTAACATTTAAAAATCAATCTATTTGTTA
AAGGTAAGGAGGTATTTGAA

Downstream 100 bases:

>100_bases
TCCTCTTCTATGGAGGTGTTAAAATGCGTGCCTCTAACAGACATGAATGTCAAGGATCTGAACCCATTTTTGATCTAAAT
ATCGTGCGGTCAATTAAAAA

Product: signal peptide peptidase SppA, 36K type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MNEAEKSSLKLFVLKALIVVGGIAAFFIIALSSFFLLGGAFISLLDADPVEEDDLVYVIDLEGEISEAAGPGPGGLGISP
RIVQESLDKAKADNAEAVVLRVNSPGGTVAASQEIASIIDDFELPTVVSMADSATSGGYYISAAADRIKAQDTSTTGSIG
VISVMYNFQELYDNLGIEVEVIKTGEYKDMGFETMTEEERQIIQDLSDEMYEHFVAEVSDYRDMDKEDVYEVATGEIMTG
TAAYEQGLVDGLGGIDRAVDKAGELAGIEDPNTRWLEPEGLFDQLFFPMVQESDLLELDSLSEETEQIDKARNLPSVEFR
YQSNF

Sequences:

>Translated_325_residues
MNEAEKSSLKLFVLKALIVVGGIAAFFIIALSSFFLLGGAFISLLDADPVEEDDLVYVIDLEGEISEAAGPGPGGLGISP
RIVQESLDKAKADNAEAVVLRVNSPGGTVAASQEIASIIDDFELPTVVSMADSATSGGYYISAAADRIKAQDTSTTGSIG
VISVMYNFQELYDNLGIEVEVIKTGEYKDMGFETMTEEERQIIQDLSDEMYEHFVAEVSDYRDMDKEDVYEVATGEIMTG
TAAYEQGLVDGLGGIDRAVDKAGELAGIEDPNTRWLEPEGLFDQLFFPMVQESDLLELDSLSEETEQIDKARNLPSVEFR
YQSNF
>Mature_325_residues
MNEAEKSSLKLFVLKALIVVGGIAAFFIIALSSFFLLGGAFISLLDADPVEEDDLVYVIDLEGEISEAAGPGPGGLGISP
RIVQESLDKAKADNAEAVVLRVNSPGGTVAASQEIASIIDDFELPTVVSMADSATSGGYYISAAADRIKAQDTSTTGSIG
VISVMYNFQELYDNLGIEVEVIKTGEYKDMGFETMTEEERQIIQDLSDEMYEHFVAEVSDYRDMDKEDVYEVATGEIMTG
TAAYEQGLVDGLGGIDRAVDKAGELAGIEDPNTRWLEPEGLFDQLFFPMVQESDLLELDSLSEETEQIDKARNLPSVEFR
YQSNF

Specific function: Digestion of the cleaved signal peptides [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=178, Percent_Identity=38.7640449438202, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787527, Length=212, Percent_Identity=33.0188679245283, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 35303; Mature: 35303

Theoretical pI: Translated: 3.71; Mature: 3.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEAEKSSLKLFVLKALIVVGGIAAFFIIALSSFFLLGGAFISLLDADPVEEDDLVYVID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
LEGEISEAAGPGPGGLGISPRIVQESLDKAKADNAEAVVLRVNSPGGTVAASQEIASIID
CCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
DFELPTVVSMADSATSGGYYISAAADRIKAQDTSTTGSIGVISVMYNFQELYDNLGIEVE
CCCCCHHHHHHCCCCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
VIKTGEYKDMGFETMTEEERQIIQDLSDEMYEHFVAEVSDYRDMDKEDVYEVATGEIMTG
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEC
TAAYEQGLVDGLGGIDRAVDKAGELAGIEDPNTRWLEPEGLFDQLFFPMVQESDLLELDS
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHCCCCCHHHHH
LSEETEQIDKARNLPSVEFRYQSNF
HHHHHHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MNEAEKSSLKLFVLKALIVVGGIAAFFIIALSSFFLLGGAFISLLDADPVEEDDLVYVID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
LEGEISEAAGPGPGGLGISPRIVQESLDKAKADNAEAVVLRVNSPGGTVAASQEIASIID
CCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
DFELPTVVSMADSATSGGYYISAAADRIKAQDTSTTGSIGVISVMYNFQELYDNLGIEVE
CCCCCHHHHHHCCCCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
VIKTGEYKDMGFETMTEEERQIIQDLSDEMYEHFVAEVSDYRDMDKEDVYEVATGEIMTG
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEC
TAAYEQGLVDGLGGIDRAVDKAGELAGIEDPNTRWLEPEGLFDQLFFPMVQESDLLELDS
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHCCCCCHHHHH
LSEETEQIDKARNLPSVEFRYQSNF
HHHHHHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]