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The map label for this gene is tynA [C]

Identifier: 188587289

GI number: 188587289

Start: 2902998

End: 2904542

Strand: Direct

Name: tynA [C]

Synonym: Nther_2692

Alternate gene names: 188587289

Gene position: 2902998-2904542 (Clockwise)

Preceding gene: 188587281

Following gene: 188587301

Centisome position: 91.71

GC content: 38.83

Gene sequence:

>1545_bases
ATGTCGATATTTCAAAGAACTGTGTTTTTATCTTTAATTATTATTCTATTACTTTCGTGTCTTTCGTCTTTGGCCTTTGC
TTCAAGTGATCTTACAACAAAAGAGGACAAGTTAGTAGAAACCGATAGAGGTGATTATCGTGTAAACTATATTAAAATAC
CTCTAGCCGGTGATTATGGTTTTACAACTTCATATGATGAAGTGGGCACTGTTGATTCCCTATCTTCCCATGCCCAAAGG
GAAGACGGTATAGCTGCCATCAACGGTACCTTCTTCGATGCTTACACTTCTGAAGATGATGAAAGGTATCCTTCTGGTGC
AATTATGAAAGATGGACAATTGCTTCATCTTATGGGTTTTGGCTCTACCTTTGCTGTTAAAAGTGATGATGGTATCAAAA
ATATTAAAGATCTAGACGTTTCTCGAATGAGATTTGGTCTAAACCTGGTTATTGAAGACCGTGATATCAGAATTGGTAGG
ATAAACCATCCTTCTGATAATTCTAACATGATCATTGCATATACTCCTGAATTTTCTAAAGATGTGATAGATGAACAAGG
AACAAAATTAGTTGTAGAAAATAACAGAATTGTAGAATTCACTGATGGACCAGCAGAGATACCGGAAAACGGTTTTGTCG
TCGAACTTGGTACACAACAGGCGGTTTCACAACTCCCAGAAAACTATTCCCCAGGAGATAAAGCAAAACTCAAACCATCT
GTTAGTGACGAAGATAGAGAGGAGCCAATTGAAATAGAAGATTTTATTCATATGGTTGGAGCCGGACCAAAACTTGTCAA
TAATGGTAGAGAAGATGTTGATCTAGAAAAAGACCAGATGACCGGTGAGAGGCATACTATCAAGGCTCGAAGAAGCTTCA
TTGGTTACAATGACAATGAAGTGATCATGGGAACTGTTGACGGTGCTAACCATGAAGATACGGCTGCTATATGTGTTGAA
TTAGGACTGACAGAAGCTATGGCTCTAGACGGTGGTGCAAGTTCAGGTCTTTATTATGAAGGTGATTACATAACAAGGCC
CGGTAGAGAAATTAGTAATGCTTTGGTTGTAAACAATATAAGTGAACCGGAAGATCCAGGAATGAGCCCATCAGATGGAG
GACCAGGTTCAGGTGTAGGTAGAAGCAGTATCCTTGAACTTGAACCGGGAAACTATACAGTAAAGAAATTTGACTCTAAT
AGATCAGAACAAAGTAAGAAAGGTAGTTGGGAACTAGATAGTGCGCCCATTATTAGAGATGGCCGTACATTAATGCCACT
GCGAGGGGTTATAGATAAATTAGGTGCTTCCCTTGATTGGGATAACAGCTCCCAAGAAGTAACGATTAAAGATGATGGAG
TGGAAGTGAAGCTTACTATTGGTGAAACAACTGCTAAGGTTAATGGAGAATCCAAAATAATGGAGATTTCACCTATAATA
GAAGACAGCCGGACGTTAATTCCGCTTAGATATGCAAATGAGCTTTTAGGCCATAATGTAGATTGGATAAGTGGAGAAGA
GGTTATTGAGATTAGAACAAAGTAG

Upstream 100 bases:

>100_bases
CTGAAGATTTTTCTTCTTTATTCCAGTTTTTTGCAGGTAGTTTTATTTATAAAGAGAATATATTACTGTGTGTTAATCTT
ATATAGATAGGGGGATTTAA

Downstream 100 bases:

>100_bases
TAAGAATTCTAAACCATCCTCTATTATAAGTAGAGGATGGTTTTAGTTTCTGGAAAGATTTGTTACTACTCCCCCTTCGT
TTAATGCCGGATCTAGAGCT

Product: copper amine oxidase domain protein

Products: Hydrogen peroxide; ammonia; Phenylacetaldehyde [C]

Alternate protein names: Copper Amine Oxidase Domain-Containing Protein; Copper Amine Oxidase-Like Protein; N-Acetylmuramoyl-L-Alanine Amidase; Copper Amine Oxidase N- Domain Family; Copper Amine Oxidase-Like; Cell Wall Hydrolase/Autolysin; Copper Amine Oxidase N- Domain Protein; Protease; Amylopullulanase; SCP-Like Extracellular Protease; Peptidase; Papain Family Cysteine Protease; D-Alanyl-D-Alanine Carboxypeptidase; Minor Extracellular Protease

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MSIFQRTVFLSLIIILLLSCLSSLAFASSDLTTKEDKLVETDRGDYRVNYIKIPLAGDYGFTTSYDEVGTVDSLSSHAQR
EDGIAAINGTFFDAYTSEDDERYPSGAIMKDGQLLHLMGFGSTFAVKSDDGIKNIKDLDVSRMRFGLNLVIEDRDIRIGR
INHPSDNSNMIIAYTPEFSKDVIDEQGTKLVVENNRIVEFTDGPAEIPENGFVVELGTQQAVSQLPENYSPGDKAKLKPS
VSDEDREEPIEIEDFIHMVGAGPKLVNNGREDVDLEKDQMTGERHTIKARRSFIGYNDNEVIMGTVDGANHEDTAAICVE
LGLTEAMALDGGASSGLYYEGDYITRPGREISNALVVNNISEPEDPGMSPSDGGPGSGVGRSSILELEPGNYTVKKFDSN
RSEQSKKGSWELDSAPIIRDGRTLMPLRGVIDKLGASLDWDNSSQEVTIKDDGVEVKLTIGETTAKVNGESKIMEISPII
EDSRTLIPLRYANELLGHNVDWISGEEVIEIRTK

Sequences:

>Translated_514_residues
MSIFQRTVFLSLIIILLLSCLSSLAFASSDLTTKEDKLVETDRGDYRVNYIKIPLAGDYGFTTSYDEVGTVDSLSSHAQR
EDGIAAINGTFFDAYTSEDDERYPSGAIMKDGQLLHLMGFGSTFAVKSDDGIKNIKDLDVSRMRFGLNLVIEDRDIRIGR
INHPSDNSNMIIAYTPEFSKDVIDEQGTKLVVENNRIVEFTDGPAEIPENGFVVELGTQQAVSQLPENYSPGDKAKLKPS
VSDEDREEPIEIEDFIHMVGAGPKLVNNGREDVDLEKDQMTGERHTIKARRSFIGYNDNEVIMGTVDGANHEDTAAICVE
LGLTEAMALDGGASSGLYYEGDYITRPGREISNALVVNNISEPEDPGMSPSDGGPGSGVGRSSILELEPGNYTVKKFDSN
RSEQSKKGSWELDSAPIIRDGRTLMPLRGVIDKLGASLDWDNSSQEVTIKDDGVEVKLTIGETTAKVNGESKIMEISPII
EDSRTLIPLRYANELLGHNVDWISGEEVIEIRTK
>Mature_513_residues
SIFQRTVFLSLIIILLLSCLSSLAFASSDLTTKEDKLVETDRGDYRVNYIKIPLAGDYGFTTSYDEVGTVDSLSSHAQRE
DGIAAINGTFFDAYTSEDDERYPSGAIMKDGQLLHLMGFGSTFAVKSDDGIKNIKDLDVSRMRFGLNLVIEDRDIRIGRI
NHPSDNSNMIIAYTPEFSKDVIDEQGTKLVVENNRIVEFTDGPAEIPENGFVVELGTQQAVSQLPENYSPGDKAKLKPSV
SDEDREEPIEIEDFIHMVGAGPKLVNNGREDVDLEKDQMTGERHTIKARRSFIGYNDNEVIMGTVDGANHEDTAAICVEL
GLTEAMALDGGASSGLYYEGDYITRPGREISNALVVNNISEPEDPGMSPSDGGPGSGVGRSSILELEPGNYTVKKFDSNR
SEQSKKGSWELDSAPIIRDGRTLMPLRGVIDKLGASLDWDNSSQEVTIKDDGVEVKLTIGETTAKVNGESKIMEISPIIE
DSRTLIPLRYANELLGHNVDWISGEEVIEIRTK

Specific function: The Enzyme Prefers Aromatic Over Aliphatic Amines. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.4.3.6 [C]

Molecular weight: Translated: 56409; Mature: 56277

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFQRTVFLSLIIILLLSCLSSLAFASSDLTTKEDKLVETDRGDYRVNYIKIPLAGDYG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEEEEEEEECCCC
FTTSYDEVGTVDSLSSHAQREDGIAAINGTFFDAYTSEDDERYPSGAIMKDGQLLHLMGF
CCCCCCCCCCHHHHHHHHHHHCCEEEECCEEEEEECCCCCCCCCCCCEEECCCEEEEEEC
GSTFAVKSDDGIKNIKDLDVSRMRFGLNLVIEDRDIRIGRINHPSDNSNMIIAYTPEFSK
CCEEEEECCCCCCCHHHCCHHHHEECCEEEEECCCEEEEECCCCCCCCCEEEEECCCCCH
DVIDEQGTKLVVENNRIVEFTDGPAEIPENGFVVELGTQQAVSQLPENYSPGDKAKLKPS
HHHCCCCCEEEEECCEEEEECCCCCCCCCCCEEEEECCHHHHHHCCCCCCCCCCCEECCC
VSDEDREEPIEIEDFIHMVGAGPKLVNNGREDVDLEKDQMTGERHTIKARRSFIGYNDNE
CCCCCCCCCCCHHHHHHHHCCCHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCCE
VIMGTVDGANHEDTAAICVELGLTEAMALDGGASSGLYYEGDYITRPGREISNALVVNNI
EEEEEECCCCCCCCEEEEEECCCCHHEEECCCCCCCEEECCCEEECCCHHHCCEEEECCC
SEPEDPGMSPSDGGPGSGVGRSSILELEPGNYTVKKFDSNRSEQSKKGSWELDSAPIIRD
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCHHCCCCCCCCCCCEEEC
GRTLMPLRGVIDKLGASLDWDNSSQEVTIKDDGVEVKLTIGETTAKVNGESKIMEISPII
CCEECHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEECCEEEEECCCCEEEEECCCC
EDSRTLIPLRYANELLGHNVDWISGEEVIEIRTK
CCCCEEEEHHHHHHHHCCCCCEECCCEEEEEECC
>Mature Secondary Structure 
SIFQRTVFLSLIIILLLSCLSSLAFASSDLTTKEDKLVETDRGDYRVNYIKIPLAGDYG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEEEEEEEECCCC
FTTSYDEVGTVDSLSSHAQREDGIAAINGTFFDAYTSEDDERYPSGAIMKDGQLLHLMGF
CCCCCCCCCCHHHHHHHHHHHCCEEEECCEEEEEECCCCCCCCCCCCEEECCCEEEEEEC
GSTFAVKSDDGIKNIKDLDVSRMRFGLNLVIEDRDIRIGRINHPSDNSNMIIAYTPEFSK
CCEEEEECCCCCCCHHHCCHHHHEECCEEEEECCCEEEEECCCCCCCCCEEEEECCCCCH
DVIDEQGTKLVVENNRIVEFTDGPAEIPENGFVVELGTQQAVSQLPENYSPGDKAKLKPS
HHHCCCCCEEEEECCEEEEECCCCCCCCCCCEEEEECCHHHHHHCCCCCCCCCCCEECCC
VSDEDREEPIEIEDFIHMVGAGPKLVNNGREDVDLEKDQMTGERHTIKARRSFIGYNDNE
CCCCCCCCCCCHHHHHHHHCCCHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCCE
VIMGTVDGANHEDTAAICVELGLTEAMALDGGASSGLYYEGDYITRPGREISNALVVNNI
EEEEEECCCCCCCCEEEEEECCCCHHEEECCCCCCCEEECCCEEECCCHHHCCEEEECCC
SEPEDPGMSPSDGGPGSGVGRSSILELEPGNYTVKKFDSNRSEQSKKGSWELDSAPIIRD
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCHHCCCCCCCCCCCEEEC
GRTLMPLRGVIDKLGASLDWDNSSQEVTIKDDGVEVKLTIGETTAKVNGESKIMEISPII
CCEECHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEECCEEEEECCCCEEEEECCCC
EDSRTLIPLRYANELLGHNVDWISGEEVIEIRTK
CCCCEEEEHHHHHHHHCCCCCEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyrroloquinoline-quinone [C]

Metal ions: Co2+; Copper; Manganese; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; O2; Phenethylamine [C]

Specific reaction: H2O + O2 + Phenethylamine --> Hydrogen peroxide + ammonia + Phenylacetaldehyde [C]

General reaction: Deamination; Redox reaction [C]

Inhibitor: 3, 5-Ethoxy-4-aminomethyl pyridine*2 HCl; Aminoguanidine; Arcaine sulfate; Azide; beta-Bromoethyl amine; Cuprizone; Cyanide; Diethyl dithiocarbamate; Histamine; Hydroxylamine; Iproniazid; Isoniazid selective inhibitors; N-Isopropyl - alpha-(2-methyl -hydr

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA