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The map label for this gene is regA [H]

Identifier: 188587288

GI number: 188587288

Start: 2900597

End: 2901664

Strand: Reverse

Name: regA [H]

Synonym: Nther_2690

Alternate gene names: 188587288

Gene position: 2901664-2900597 (Counterclockwise)

Preceding gene: 188587290

Following gene: 188587287

Centisome position: 91.66

GC content: 42.51

Gene sequence:

>1068_bases
ATGGCCACGATTAAAGATATTGCCAAGAAAGCTGGGGTTTCAATCACCTCTGTTTCCCAGGTGCTAAACAACAAGGATAT
GGGCATCAAAGAAGAGACCAAAGAAAAGATCCTTGCAGCAGCCCGGGAGCTGGACTATAAGCCTAATTACCTCGCTCGGG
GCTTAATTACTAAAAAGACCAATACCTTGGGACTTATCATTCCAGACATTACCAACCCTTTTTTCCCCCAGGTGGTCAGG
GCCATTGAGGATACGGCCAATTACCAAGGATACAATATGATACTTTGCAATACCGATGATGATGTGGACAAGGAGAAATT
ATACCTCAGAGTTCTTGAAGAAAAATGCGTAGACGGAATTATTTTTACAAGTTCAACTAAATCTTCCAAAAGTTATCTGG
ACCACCTGGAGAACAATGATACACCCTTTGTCCTTTTAGACAGGAGTTTTTCAGGTCCTTTGGACTTTCCCAAAGTTTAT
ACTGACGGTTATAAAGGTATTAAACTAGCCATGAATCACCTGATTACAAGAGGCCATAGAGACATTGCTTTTCTTTCAGG
TCCTGAAACATCCCAAACGGCCAAAGACCGCCTCGAGGGATACAGACAAGCCTTGAGTGAAGCCGGTCTCACTCCCGAAT
CAGAGTCACAATTGATCTATTATGGTGATTACAAGGCCCTCTCGGGAGAGCAAGGAATAGCCGAGCTGTTGGATACAAAT
CCGCATATCACAGCAGTAGTAGCAGCTAATGATCTCATGGCGGTGGGAGCTATGCGAACTATTAAAAATCGCGGCCTAAA
AATTCCGGAGGATATATCAATTATCGGATTTGACAACATTCAAACCTCACGACTAGTAGATCCACCCCTGACTACGGTGG
CACAACCTTCTTATCAAATGGGACAAATGGCGACTGATATTTTGATCGACATGATCGAAAAGACCACTAATATTACTGGG
AAAAGCACTCATCCCGAAACTAATCAAACTTCACAGGATTTCGAATCACTTAAAATCCAAGAAGTCAAGCTAGAGCCCGA
ATTAATCATCAGAAATTCAGTTAAATAG

Upstream 100 bases:

>100_bases
AAGGTTTTAGTAAAACGATTTAGTAAAACCTTTTATGATCCAATCGAGATTATTTAAGTAAGTTACGATATTAATATTTT
CTTATGAAAGGACGTCCCCA

Downstream 100 bases:

>100_bases
TATGGATTAAGATTAAATAAGGAATAGACTTCGGCCAGTGAGGCCCAGAAATCTGGAAATAAGTTATCAACATTCAACTT
TTATACATCCAAAAAATAAA

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MATIKDIAKKAGVSITSVSQVLNNKDMGIKEETKEKILAAARELDYKPNYLARGLITKKTNTLGLIIPDITNPFFPQVVR
AIEDTANYQGYNMILCNTDDDVDKEKLYLRVLEEKCVDGIIFTSSTKSSKSYLDHLENNDTPFVLLDRSFSGPLDFPKVY
TDGYKGIKLAMNHLITRGHRDIAFLSGPETSQTAKDRLEGYRQALSEAGLTPESESQLIYYGDYKALSGEQGIAELLDTN
PHITAVVAANDLMAVGAMRTIKNRGLKIPEDISIIGFDNIQTSRLVDPPLTTVAQPSYQMGQMATDILIDMIEKTTNITG
KSTHPETNQTSQDFESLKIQEVKLEPELIIRNSVK

Sequences:

>Translated_355_residues
MATIKDIAKKAGVSITSVSQVLNNKDMGIKEETKEKILAAARELDYKPNYLARGLITKKTNTLGLIIPDITNPFFPQVVR
AIEDTANYQGYNMILCNTDDDVDKEKLYLRVLEEKCVDGIIFTSSTKSSKSYLDHLENNDTPFVLLDRSFSGPLDFPKVY
TDGYKGIKLAMNHLITRGHRDIAFLSGPETSQTAKDRLEGYRQALSEAGLTPESESQLIYYGDYKALSGEQGIAELLDTN
PHITAVVAANDLMAVGAMRTIKNRGLKIPEDISIIGFDNIQTSRLVDPPLTTVAQPSYQMGQMATDILIDMIEKTTNITG
KSTHPETNQTSQDFESLKIQEVKLEPELIIRNSVK
>Mature_354_residues
ATIKDIAKKAGVSITSVSQVLNNKDMGIKEETKEKILAAARELDYKPNYLARGLITKKTNTLGLIIPDITNPFFPQVVRA
IEDTANYQGYNMILCNTDDDVDKEKLYLRVLEEKCVDGIIFTSSTKSSKSYLDHLENNDTPFVLLDRSFSGPLDFPKVYT
DGYKGIKLAMNHLITRGHRDIAFLSGPETSQTAKDRLEGYRQALSEAGLTPESESQLIYYGDYKALSGEQGIAELLDTNP
HITAVVAANDLMAVGAMRTIKNRGLKIPEDISIIGFDNIQTSRLVDPPLTTVAQPSYQMGQMATDILIDMIEKTTNITGK
STHPETNQTSQDFESLKIQEVKLEPELIIRNSVK

Specific function: Involved in the regulation of amylase production [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=312, Percent_Identity=35.8974358974359, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1787948, Length=356, Percent_Identity=33.7078651685393, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1790194, Length=317, Percent_Identity=36.5930599369085, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1789202, Length=302, Percent_Identity=34.7682119205298, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1788474, Length=324, Percent_Identity=33.3333333333333, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1789068, Length=315, Percent_Identity=32.0634920634921, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1786540, Length=310, Percent_Identity=31.6129032258064, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=29.8412698412698, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI48994940, Length=324, Percent_Identity=29.6296296296296, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787906, Length=335, Percent_Identity=28.6567164179104, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790715, Length=315, Percent_Identity=26.984126984127, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786268, Length=309, Percent_Identity=26.2135922330097, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789456, Length=321, Percent_Identity=29.2834890965732, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790689, Length=325, Percent_Identity=26.1538461538462, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1790192, Length=224, Percent_Identity=24.1071428571429, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789993, Length=189, Percent_Identity=29.1005291005291, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 39414; Mature: 39283

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIKDIAKKAGVSITSVSQVLNNKDMGIKEETKEKILAAARELDYKPNYLARGLITKKT
CCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCEEEECC
NTLGLIIPDITNPFFPQVVRAIEDTANYQGYNMILCNTDDDVDKEKLYLRVLEEKCVDGI
CEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCE
IFTSSTKSSKSYLDHLENNDTPFVLLDRSFSGPLDFPKVYTDGYKGIKLAMNHLITRGHR
EEECCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCC
DIAFLSGPETSQTAKDRLEGYRQALSEAGLTPESESQLIYYGDYKALSGEQGIAELLDTN
CEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCC
PHITAVVAANDLMAVGAMRTIKNRGLKIPEDISIIGFDNIQTSRLVDPPLTTVAQPSYQM
CCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCHHH
GQMATDILIDMIEKTTNITGKSTHPETNQTSQDFESLKIQEVKLEPELIIRNSVK
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCEEEEEECCCEEEECCCCC
>Mature Secondary Structure 
ATIKDIAKKAGVSITSVSQVLNNKDMGIKEETKEKILAAARELDYKPNYLARGLITKKT
CCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCEEEECC
NTLGLIIPDITNPFFPQVVRAIEDTANYQGYNMILCNTDDDVDKEKLYLRVLEEKCVDGI
CEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCE
IFTSSTKSSKSYLDHLENNDTPFVLLDRSFSGPLDFPKVYTDGYKGIKLAMNHLITRGHR
EEECCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCC
DIAFLSGPETSQTAKDRLEGYRQALSEAGLTPESESQLIYYGDYKALSGEQGIAELLDTN
CEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCC
PHITAVVAANDLMAVGAMRTIKNRGLKIPEDISIIGFDNIQTSRLVDPPLTTVAQPSYQM
CCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCHHH
GQMATDILIDMIEKTTNITGKSTHPETNQTSQDFESLKIQEVKLEPELIIRNSVK
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCEEEEEECCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7539689 [H]