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The map label for this gene is rbsK [H]

Identifier: 188587287

GI number: 188587287

Start: 2899411

End: 2900448

Strand: Reverse

Name: rbsK [H]

Synonym: Nther_2689

Alternate gene names: 188587287

Gene position: 2900448-2899411 (Counterclockwise)

Preceding gene: 188587288

Following gene: 188587286

Centisome position: 91.63

GC content: 46.82

Gene sequence:

>1038_bases
TTGTCTGTAAAATTTACAGTTATGGGAAGCTTAAATATGGACTTCGTATTGTCTGTCCCCAGGCTTCCCCAGGAAGGCGA
AACACTCCTAGCCCAAAATTTTTCTACTTTTCCCGGCGGAAAAGGCGCCAATCAAGCTGTTGCCCTGGCACGGTTGGGAG
GCCAGGTGAACATGATCGGTGCAGTAGGAGACGATGATTTGGGTAATAATCTACTAAGAAACTTGGAACAAGAACAGATT
GATACAACAGGAGTTCAGTGCCTAGCTGACACTCCTACAGGAAATGCCTTTATCACAGTCGATCAACAGGGTAAAAACAC
CATTCTTGTATATCCAGGCGCCAATGGTGAACTGAAAACATCTTGGGTGCCACAGCATAAGGAATTGATCCAAAATTCAG
AATATTTGCTGATGCAGTTGGAGACTCCCCTAGAAGTAGTAGAGGCCACGGCTGAGTTAGCTGACAGTTTAGGGACCAAG
GTTATCTTAAATCCAGCACCTGGCCAGGAACTGTCCCAAAACCTATTAAAACGTGTCCACTTGTTAACTCCCAATGAAAC
TGAACTATCTGTCATATCAGGTATGACCACAGAAACTAGGGAGGAACAGATAGCTGCCGCCAGGCATCTGACTGACTTGG
GTGTGGATCAGGTAGTTGTCACTCTGGGCTCAGAAGGGGCCTTTCATGTGGACAAGAACATGGGTCAACAAGGCACTCAT
GGACATCATAACACACACTGCAATCACGGTACTCGCGGTACTTACGGAACTCGCGGTACTCACGGCACTCAAGACTCTCA
AAACCCTCAAGAGGCCACCTTTGTTGACAGCTTTTCGGTTAAAGCTGTAGATACCACAGCAGCAGGTGATAGCTTTACAG
CAGCCTTGGCAATTGCTTTGGGACAGGGACAAAGCATAGAAAACGCCCTCAAATATGCTTCAGCCGTAGCGGCTATCACA
GTGACCAAAGAAGGAGCACAAAGCTCATTACCCTATTCTCATCAGGTAGATACCTTCCTGAAGAAAGGGGAACTGTAA

Upstream 100 bases:

>100_bases
AAATCTGGAAATAAGTTATCAACATTCAACTTTTATACATCCAAAAAATAAACAAATTAAGCAAGGGTTTTGAATATAGT
AAGGCAGGGGGGTAATGCTA

Downstream 100 bases:

>100_bases
ATGAAAAAAACAACTTTGCTGAATAGCGAAATTTCCCGAGTTACTTCTCAAATGGGCCATACTGACGGATTGACTATTTC
CGATGCTGGACCTCCCATCC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSVKFTVMGSLNMDFVLSVPRLPQEGETLLAQNFSTFPGGKGANQAVALARLGGQVNMIGAVGDDDLGNNLLRNLEQEQI
DTTGVQCLADTPTGNAFITVDQQGKNTILVYPGANGELKTSWVPQHKELIQNSEYLLMQLETPLEVVEATAELADSLGTK
VILNPAPGQELSQNLLKRVHLLTPNETELSVISGMTTETREEQIAAARHLTDLGVDQVVVTLGSEGAFHVDKNMGQQGTH
GHHNTHCNHGTRGTYGTRGTHGTQDSQNPQEATFVDSFSVKAVDTTAAGDSFTAALAIALGQGQSIENALKYASAVAAIT
VTKEGAQSSLPYSHQVDTFLKKGEL

Sequences:

>Translated_345_residues
MSVKFTVMGSLNMDFVLSVPRLPQEGETLLAQNFSTFPGGKGANQAVALARLGGQVNMIGAVGDDDLGNNLLRNLEQEQI
DTTGVQCLADTPTGNAFITVDQQGKNTILVYPGANGELKTSWVPQHKELIQNSEYLLMQLETPLEVVEATAELADSLGTK
VILNPAPGQELSQNLLKRVHLLTPNETELSVISGMTTETREEQIAAARHLTDLGVDQVVVTLGSEGAFHVDKNMGQQGTH
GHHNTHCNHGTRGTYGTRGTHGTQDSQNPQEATFVDSFSVKAVDTTAAGDSFTAALAIALGQGQSIENALKYASAVAAIT
VTKEGAQSSLPYSHQVDTFLKKGEL
>Mature_344_residues
SVKFTVMGSLNMDFVLSVPRLPQEGETLLAQNFSTFPGGKGANQAVALARLGGQVNMIGAVGDDDLGNNLLRNLEQEQID
TTGVQCLADTPTGNAFITVDQQGKNTILVYPGANGELKTSWVPQHKELIQNSEYLLMQLETPLEVVEATAELADSLGTKV
ILNPAPGQELSQNLLKRVHLLTPNETELSVISGMTTETREEQIAAARHLTDLGVDQVVVTLGSEGAFHVDKNMGQQGTHG
HHNTHCNHGTRGTYGTRGTHGTQDSQNPQEATFVDSFSVKAVDTTAAGDSFTAALAIALGQGQSIENALKYASAVAAITV
TKEGAQSSLPYSHQVDTFLKKGEL

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=332, Percent_Identity=33.1325301204819, Blast_Score=152, Evalue=6e-37,
Organism=Escherichia coli, GI1790193, Length=338, Percent_Identity=37.2781065088757, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI87082343, Length=341, Percent_Identity=27.5659824046921, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788491, Length=290, Percent_Identity=20.3448275862069, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=327, Percent_Identity=33.6391437308869, Blast_Score=150, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6319884, Length=352, Percent_Identity=30.3977272727273, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI20128807, Length=336, Percent_Identity=32.7380952380952, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24583886, Length=342, Percent_Identity=28.6549707602339, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 36690; Mature: 36559

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKFTVMGSLNMDFVLSVPRLPQEGETLLAQNFSTFPGGKGANQAVALARLGGQVNMIG
CCEEEEEEECCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEE
AVGDDDLGNNLLRNLEQEQIDTTGVQCLADTPTGNAFITVDQQGKNTILVYPGANGELKT
ECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCEEEEEEECCCCCEEE
SWVPQHKELIQNSEYLLMQLETPLEVVEATAELADSLGTKVILNPAPGQELSQNLLKRVH
CCCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHE
LLTPNETELSVISGMTTETREEQIAAARHLTDLGVDQVVVTLGSEGAFHVDKNMGQQGTH
ECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCC
GHHNTHCNHGTRGTYGTRGTHGTQDSQNPQEATFVDSFSVKAVDTTAAGDSFTAALAIAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCCCHHEEEEEEE
GQGQSIENALKYASAVAAITVTKEGAQSSLPYSHQVDTFLKKGEL
CCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SVKFTVMGSLNMDFVLSVPRLPQEGETLLAQNFSTFPGGKGANQAVALARLGGQVNMIG
CEEEEEEECCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEE
AVGDDDLGNNLLRNLEQEQIDTTGVQCLADTPTGNAFITVDQQGKNTILVYPGANGELKT
ECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCEEEEEEECCCCCEEE
SWVPQHKELIQNSEYLLMQLETPLEVVEATAELADSLGTKVILNPAPGQELSQNLLKRVH
CCCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHE
LLTPNETELSVISGMTTETREEQIAAARHLTDLGVDQVVVTLGSEGAFHVDKNMGQQGTH
ECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCC
GHHNTHCNHGTRGTYGTRGTHGTQDSQNPQEATFVDSFSVKAVDTTAAGDSFTAALAIAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCCCHHEEEEEEE
GQGQSIENALKYASAVAAITVTKEGAQSSLPYSHQVDTFLKKGEL
CCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]