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The map label for this gene is kdgR [H]

Identifier: 188587268

GI number: 188587268

Start: 2877222

End: 2877980

Strand: Reverse

Name: kdgR [H]

Synonym: Nther_2670

Alternate gene names: 188587268

Gene position: 2877980-2877222 (Counterclockwise)

Preceding gene: 188587270

Following gene: 188587267

Centisome position: 90.92

GC content: 33.6

Gene sequence:

>759_bases
ATGACTCAACAAGAAAAGTTATCAAGTAACCGTAAAGCTATCAAGGTTTTAAAGGCTTTAGCTCAAGAACCTTATGAGTT
TTCTGCTAAGGAAATAAGTGAACAGTTAAATATAAATAGAACTTCAGTACATCGAATTTTAAATGATTATATGCAAGAGA
AACTAGTCACCCAGAATAGGTATACTAAAAAGTACAAGTTAGGGCCAGAAACTTTTAAAATTGGTGCCGCGTATTTAAAT
GTTAAAAATATTAATAATGATATTGTTGGAATAGTTAATGAGATTGCTACTAAGACAAAAGAATCAGTGGGTTTATATGT
CAAAGATGAAGATGTGATCATTTCACTTTATGAATCAGAAAGCTTTCAGTTACAGAAAATGGGATACAAGGCAGGCAGCA
CTTACCCTATCAATGCAGGTTCTGTAGGTAAATGCATTACAGCCTTTTTAGATGAAGAAAGAATCGAGGAATTATTAGAA
AATACTAAGTTAGAGCAATATACCTCTCATACTATAACTGATAAAGAGGAATTAAGGAAAGAATTCAAACAGATACGAGC
GCAAGGTTATGCAATCAGTGATGAAGATAAAGTACTTGGAAGATACGGAATTGCTGCACCAGTTTGGAACAGTCAAGGAC
ATGTTGTTGCTAGCGTGGCAGTTGCATGTCAAAAAACTGGCCTGACCACTAACAAGATAGAAACAATCAAAAATAATATC
TTGAAAGGAGCTGAAGAAATTTCTGATTTAATGCCATAA

Upstream 100 bases:

>100_bases
GACGAATATTGTCAGAAAGTTCGTATATAAAACATATGTTCACATATAAAACAAAAATATTGGTTTTTATTAGTTTCGAT
AAGGAGGTGCCCTCCCAAAA

Downstream 100 bases:

>100_bases
GGAGGTGATATCTGCGGGGAAATCTATGAATTTAGCAGTTAAAATACTAAATTACAAGGAGGCATTGTATGTCTGACAAA
TTAAAGGACAAGCTTTATCA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTQQEKLSSNRKAIKVLKALAQEPYEFSAKEISEQLNINRTSVHRILNDYMQEKLVTQNRYTKKYKLGPETFKIGAAYLN
VKNINNDIVGIVNEIATKTKESVGLYVKDEDVIISLYESESFQLQKMGYKAGSTYPINAGSVGKCITAFLDEERIEELLE
NTKLEQYTSHTITDKEELRKEFKQIRAQGYAISDEDKVLGRYGIAAPVWNSQGHVVASVAVACQKTGLTTNKIETIKNNI
LKGAEEISDLMP

Sequences:

>Translated_252_residues
MTQQEKLSSNRKAIKVLKALAQEPYEFSAKEISEQLNINRTSVHRILNDYMQEKLVTQNRYTKKYKLGPETFKIGAAYLN
VKNINNDIVGIVNEIATKTKESVGLYVKDEDVIISLYESESFQLQKMGYKAGSTYPINAGSVGKCITAFLDEERIEELLE
NTKLEQYTSHTITDKEELRKEFKQIRAQGYAISDEDKVLGRYGIAAPVWNSQGHVVASVAVACQKTGLTTNKIETIKNNI
LKGAEEISDLMP
>Mature_251_residues
TQQEKLSSNRKAIKVLKALAQEPYEFSAKEISEQLNINRTSVHRILNDYMQEKLVTQNRYTKKYKLGPETFKIGAAYLNV
KNINNDIVGIVNEIATKTKESVGLYVKDEDVIISLYESESFQLQKMGYKAGSTYPINAGSVGKCITAFLDEERIEELLEN
TKLEQYTSHTITDKEELRKEFKQIRAQGYAISDEDKVLGRYGIAAPVWNSQGHVVASVAVACQKTGLTTNKIETIKNNIL
KGAEEISDLMP

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=247, Percent_Identity=23.4817813765182, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788131, Length=250, Percent_Identity=27.6, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786468, Length=219, Percent_Identity=26.027397260274, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1786715, Length=239, Percent_Identity=25.1046025104602, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789999, Length=242, Percent_Identity=23.5537190082645, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28393; Mature: 28261

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQEKLSSNRKAIKVLKALAQEPYEFSAKEISEQLNINRTSVHRILNDYMQEKLVTQNR
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YTKKYKLGPETFKIGAAYLNVKNINNDIVGIVNEIATKTKESVGLYVKDEDVIISLYESE
CCCEEECCCHHEEHHHHEEEEECCCCHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCC
SFQLQKMGYKAGSTYPINAGSVGKCITAFLDEERIEELLENTKLEQYTSHTITDKEELRK
CHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCHHHHHCCCCCCHHHHHH
EFKQIRAQGYAISDEDKVLGRYGIAAPVWNSQGHVVASVAVACQKTGLTTNKIETIKNNI
HHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LKGAEEISDLMP
HHHHHHHHHCCC
>Mature Secondary Structure 
TQQEKLSSNRKAIKVLKALAQEPYEFSAKEISEQLNINRTSVHRILNDYMQEKLVTQNR
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YTKKYKLGPETFKIGAAYLNVKNINNDIVGIVNEIATKTKESVGLYVKDEDVIISLYESE
CCCEEECCCHHEEHHHHEEEEECCCCHHHHHHHHHHHHHHHHCEEEEECCCEEEEEECCC
SFQLQKMGYKAGSTYPINAGSVGKCITAFLDEERIEELLENTKLEQYTSHTITDKEELRK
CHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCHHHHHCCCCCCHHHHHH
EFKQIRAQGYAISDEDKVLGRYGIAAPVWNSQGHVVASVAVACQKTGLTTNKIETIKNNI
HHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LKGAEEISDLMP
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]