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The map label for this gene is asrB [H]

Identifier: 188587256

GI number: 188587256

Start: 2863056

End: 2863874

Strand: Reverse

Name: asrB [H]

Synonym: Nther_2658

Alternate gene names: 188587256

Gene position: 2863874-2863056 (Counterclockwise)

Preceding gene: 188587257

Following gene: 188587255

Centisome position: 90.47

GC content: 38.95

Gene sequence:

>819_bases
TTGTGTAATAATAACCCATTAATTCCAGTTTCAGCTAAAGTAAAAGAAATTATTACAGAAAGTAATGATGTTAAAACTTT
TCGTGTTGAACCTGAAGAAAAAATAGAGCATATGCCAGGACAATGTGCCATGCTCTCCCTCTTTGGAGTCGGAGAAGCTC
TTTTCTCCATTAGTTCACCACCTGAAAGAGAATATTTAGATTTTAGTATAAAACGGGTTGGTCAAGTTACTGAGGCTTTG
CACAATATTGAAGAGGGGCAAGAACTTGGGATTCGTGGCCCCTACGGGAATCACTTTCCAGTAAACGATCTCAAAGGTAA
GAACTTATTGTTTATTGGTGGGGGCATTGGACTCGCCCCCTTGAGATCATTAATCAAATATAGTCTGGATCACAAAGAGG
ATTATGGTGATTTACAGTTGATCTACGGGGCCAGAACTCCTGAAGATCTAATCTTTGAAAGAGATATCTACGAGAATTGG
CCTCAAGAAGATAATTTCCAGGTCAATCTATCAGTAGATGTTGAGAGTCCTGGTTGGGATGGCTTTGTAGGCTTTGTTCC
TCAATACCTGGAGGAGCTAGTTCCTAGCCCTGAAAATACAGTAGCAATTACTTGCGGTCCACCTATTATGATCAAATTCG
TACTTCAGACATTAGAAAGACTAGGCTTTAAAGATGATCAGATCGTAACAACCTTGGAGTACAAAATGAAATGCGGTGTT
GGTAAGTGCGGTCGCTGTAATATAGACGATCAGTATGTATGCAAAGATGGTCCTGTTTTCTATCTGAAAGAATTGAATCA
ATTAAAAGCTGAATTTTAA

Upstream 100 bases:

>100_bases
CAAGGGCCAATAGCTTGTGTTGGTTGCGGACGCTGTGCACAAAACTGTCCTGTTGGTATATCCATAAATACTGTTTTGAA
AAGGATTGGAGGGGAGAAGT

Downstream 100 bases:

>100_bases
AGGCCTATCAAAATAAGCACTTTATGTCTAAAATTTTTAACTAATTGGGGGGTGATAAATTTCATTCATAATTTTTAAGT
TAAGCGTATTTACAAGTTTT

Product: oxidoreductase FAD/NAD(P)-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MCNNNPLIPVSAKVKEIITESNDVKTFRVEPEEKIEHMPGQCAMLSLFGVGEALFSISSPPEREYLDFSIKRVGQVTEAL
HNIEEGQELGIRGPYGNHFPVNDLKGKNLLFIGGGIGLAPLRSLIKYSLDHKEDYGDLQLIYGARTPEDLIFERDIYENW
PQEDNFQVNLSVDVESPGWDGFVGFVPQYLEELVPSPENTVAITCGPPIMIKFVLQTLERLGFKDDQIVTTLEYKMKCGV
GKCGRCNIDDQYVCKDGPVFYLKELNQLKAEF

Sequences:

>Translated_272_residues
MCNNNPLIPVSAKVKEIITESNDVKTFRVEPEEKIEHMPGQCAMLSLFGVGEALFSISSPPEREYLDFSIKRVGQVTEAL
HNIEEGQELGIRGPYGNHFPVNDLKGKNLLFIGGGIGLAPLRSLIKYSLDHKEDYGDLQLIYGARTPEDLIFERDIYENW
PQEDNFQVNLSVDVESPGWDGFVGFVPQYLEELVPSPENTVAITCGPPIMIKFVLQTLERLGFKDDQIVTTLEYKMKCGV
GKCGRCNIDDQYVCKDGPVFYLKELNQLKAEF
>Mature_272_residues
MCNNNPLIPVSAKVKEIITESNDVKTFRVEPEEKIEHMPGQCAMLSLFGVGEALFSISSPPEREYLDFSIKRVGQVTEAL
HNIEEGQELGIRGPYGNHFPVNDLKGKNLLFIGGGIGLAPLRSLIKYSLDHKEDYGDLQLIYGARTPEDLIFERDIYENW
PQEDNFQVNLSVDVESPGWDGFVGFVPQYLEELVPSPENTVAITCGPPIMIKFVLQTLERLGFKDDQIVTTLEYKMKCGV
GKCGRCNIDDQYVCKDGPVFYLKELNQLKAEF

Specific function: This enzyme catalyzes the hydrogen sulfide production from sulfite. It is strictly anaerobic. It is regulated by electron acceptors rather than by cysteine [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI47778923, Length=211, Percent_Identity=27.9620853080569, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1787098, Length=221, Percent_Identity=27.1493212669683, Blast_Score=75, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323510, Length=189, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322146, Length=167, Percent_Identity=25.1497005988024, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281366101, Length=173, Percent_Identity=27.1676300578035, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24662934, Length=173, Percent_Identity=27.1676300578035, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24662938, Length=173, Percent_Identity=27.1676300578035, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007804, Length=174, Percent_Identity=26.4367816091954, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007806, Length=174, Percent_Identity=26.4367816091954, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938
- InterPro:   IPR014260 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30628; Mature: 30628

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCNNNPLIPVSAKVKEIITESNDVKTFRVEPEEKIEHMPGQCAMLSLFGVGEALFSISSP
CCCCCCEEECHHHHHHHHCCCCCCEEEEECHHHHHHCCCCCEEEHHHHHHHHHHHHCCCC
PEREYLDFSIKRVGQVTEALHNIEEGQELGIRGPYGNHFPVNDLKGKNLLFIGGGIGLAP
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHH
LRSLIKYSLDHKEDYGDLQLIYGARTPEDLIFERDIYENWPQEDNFQVNLSVDVESPGWD
HHHHHHHHCCCCCCCCCEEEEECCCCCHHHHEECHHHHCCCCCCCEEEEEEEEECCCCCC
GFVGFVPQYLEELVPSPENTVAITCGPPIMIKFVLQTLERLGFKDDQIVTTLEYKMKCGV
CHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCC
GKCGRCNIDDQYVCKDGPVFYLKELNQLKAEF
CCCCCCCCCCCEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MCNNNPLIPVSAKVKEIITESNDVKTFRVEPEEKIEHMPGQCAMLSLFGVGEALFSISSP
CCCCCCEEECHHHHHHHHCCCCCCEEEEECHHHHHHCCCCCEEEHHHHHHHHHHHHCCCC
PEREYLDFSIKRVGQVTEALHNIEEGQELGIRGPYGNHFPVNDLKGKNLLFIGGGIGLAP
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHH
LRSLIKYSLDHKEDYGDLQLIYGARTPEDLIFERDIYENWPQEDNFQVNLSVDVESPGWD
HHHHHHHHCCCCCCCCCEEEEECCCCCHHHHEECHHHHCCCCCCCEEEEEEEEECCCCCC
GFVGFVPQYLEELVPSPENTVAITCGPPIMIKFVLQTLERLGFKDDQIVTTLEYKMKCGV
CHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCC
GKCGRCNIDDQYVCKDGPVFYLKELNQLKAEF
CCCCCCCCCCCEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1704886; 11677609 [H]