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The map label for this gene is 188586945

Identifier: 188586945

GI number: 188586945

Start: 2484936

End: 2485604

Strand: Direct

Name: 188586945

Synonym: Nther_2337

Alternate gene names: NA

Gene position: 2484936-2485604 (Clockwise)

Preceding gene: 188586939

Following gene: 188586953

Centisome position: 78.5

GC content: 40.06

Gene sequence:

>669_bases
GTGAAATTAGAATTTATCGGTCACGGTTGTGTACAGTTGTCAGAAGGTGATGACAAAATAATCTTTGATCCCTTTATCGA
TGACAATCCAGTAGCTAAAATTTCATCATCCGATGTTTCCCCGAATTACATTCTATTAACACACTATCATGACGATCATA
AAGGAGATGCCCTAGAAATTGCCAAGGATAATGATTCATTACTTATTTCTACGGCTGAAATTGCAGGAGCCGCTGAACAA
AAGGGGGTAAAAGCCCATCCTATGCACATAGGTGGAACTAAAGAGTTCGATTTCGGTAAAGTTCGGGTAACACCAGCACT
ACACGGCTCTGGTATTGATGGTGGGTTAGCATGTGGCTTTGTAGTAGATTTTCATGGAAAGAAAGTTTATCACGCAGGAG
ATACCGGGCTATTTAGTGATATGAAATTAATATCCGAATTAGAAGAAATAGATATAGCCATCCTTCCCATAGGTGGAAAC
TTTACCATGGGAGCCGAGGAAGCTGTCATGGCAACACAATATCTAAAACCAAAGGCAGTCATGCCAGTCCACTATAATAC
TTGGCCTTTAATCCCCGCTGATGACGAGCAATTCAAAAAAGATATCCAGGAAAAAACAAATAGCGAATGCTTTGTCCTTG
AACCTGGTGACTCTATGGAAATGAATTAA

Upstream 100 bases:

>100_bases
TATAGCAAAAAAACACCTTAAAATGAAAATTTTAAATCACTACCGGCTATGGTATAATATTACAGGGAGTAATTTGCAAA
TTAACAAAGGAGGGATCCAT

Downstream 100 bases:

>100_bases
CTCTAAATCTACTACCTAACTCTACAATACACCCCATCCAGAAACAGTAAACACATCTCCATGAACACATAAAAAACAGC
CCTGACCTTGGCTTAACAGC

Product: beta-lactamase domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKLEFIGHGCVQLSEGDDKIIFDPFIDDNPVAKISSSDVSPNYILLTHYHDDHKGDALEIAKDNDSLLISTAEIAGAAEQ
KGVKAHPMHIGGTKEFDFGKVRVTPALHGSGIDGGLACGFVVDFHGKKVYHAGDTGLFSDMKLISELEEIDIAILPIGGN
FTMGAEEAVMATQYLKPKAVMPVHYNTWPLIPADDEQFKKDIQEKTNSECFVLEPGDSMEMN

Sequences:

>Translated_222_residues
MKLEFIGHGCVQLSEGDDKIIFDPFIDDNPVAKISSSDVSPNYILLTHYHDDHKGDALEIAKDNDSLLISTAEIAGAAEQ
KGVKAHPMHIGGTKEFDFGKVRVTPALHGSGIDGGLACGFVVDFHGKKVYHAGDTGLFSDMKLISELEEIDIAILPIGGN
FTMGAEEAVMATQYLKPKAVMPVHYNTWPLIPADDEQFKKDIQEKTNSECFVLEPGDSMEMN
>Mature_222_residues
MKLEFIGHGCVQLSEGDDKIIFDPFIDDNPVAKISSSDVSPNYILLTHYHDDHKGDALEIAKDNDSLLISTAEIAGAAEQ
KGVKAHPMHIGGTKEFDFGKVRVTPALHGSGIDGGLACGFVVDFHGKKVYHAGDTGLFSDMKLISELEEIDIAILPIGGN
FTMGAEEAVMATQYLKPKAVMPVHYNTWPLIPADDEQFKKDIQEKTNSECFVLEPGDSMEMN

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0173 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2337_NATTJ (B2A8L8)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001918490.1
- ProteinModelPortal:   B2A8L8
- GeneID:   6315083
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_2337
- HOGENOM:   HBG741314
- OMA:   VILLTHG
- HAMAP:   MF_00457
- InterPro:   IPR001279
- InterPro:   IPR022877
- SMART:   SM00849

Pfam domain/function: PF00753 Lactamase_B

EC number: NA

Molecular weight: Translated: 24193; Mature: 24193

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEFIGHGCVQLSEGDDKIIFDPFIDDNPVAKISSSDVSPNYILLTHYHDDHKGDALEI
CEEEEEECCEEEECCCCCEEEEECCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCEEEE
AKDNDSLLISTAEIAGAAEQKGVKAHPMHIGGTKEFDFGKVRVTPALHGSGIDGGLACGF
EECCCCEEEEEHHHCCCHHHCCCEECCEEECCCCCCCCCEEEEEEEECCCCCCCCEEEEE
VVDFHGKKVYHAGDTGLFSDMKLISELEEIDIAILPIGGNFTMGAEEAVMATQYLKPKAV
EEEECCCEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHCCCCEE
MPVHYNTWPLIPADDEQFKKDIQEKTNSECFVLEPGDSMEMN
EEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MKLEFIGHGCVQLSEGDDKIIFDPFIDDNPVAKISSSDVSPNYILLTHYHDDHKGDALEI
CEEEEEECCEEEECCCCCEEEEECCCCCCCCEEEECCCCCCCEEEEEEECCCCCCCEEEE
AKDNDSLLISTAEIAGAAEQKGVKAHPMHIGGTKEFDFGKVRVTPALHGSGIDGGLACGF
EECCCCEEEEEHHHCCCHHHCCCEECCEEECCCCCCCCCEEEEEEEECCCCCCCCEEEEE
VVDFHGKKVYHAGDTGLFSDMKLISELEEIDIAILPIGGNFTMGAEEAVMATQYLKPKAV
EEEECCCEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHCCCCEE
MPVHYNTWPLIPADDEQFKKDIQEKTNSECFVLEPGDSMEMN
EEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA