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The map label for this gene is ftsX [H]

Identifier: 188586804

GI number: 188586804

Start: 2330968

End: 2331858

Strand: Reverse

Name: ftsX [H]

Synonym: Nther_2195

Alternate gene names: 188586804

Gene position: 2331858-2330968 (Counterclockwise)

Preceding gene: 188586805

Following gene: 188586803

Centisome position: 73.66

GC content: 40.4

Gene sequence:

>891_bases
ATGAAGTTTAGAAGCTGGGCCTACTTTTTCAGTGAGGCCTTTAAAAGTGTGTTTCGAAATGGTTGGATGAGCTTGGCTTC
CATAGGGGTAGTTACAGTCACCCTATTGATGCTGGGTGTCTTTATGATAATTAACCAAAATGTGGAGTACATTACTGAAG
AAGTTCGAGGACAAGTTGAAATAGCTGTATGGCTAGAAGATGATCTGTCTTCTCGAGATCATGACGATATTAGGACAAGC
CTTATAAAAATATCCGGTGTGGAAAAGGTTAAATTTGTTTCTCAAGAGGAAGGTTTGGACCGGATGAAGGAACAGATGGG
CGAATCGGCTGTCCAAGGTTATTATGACGAACCGGATCAAAATCCTTTACCTGATATGTTTGAGGTTAATACTGTATATC
CTGAAGATGTACCTCGGGTAGCAGATGAAATTTCACAGATTTCCGGAGTCGATATGGTGGATTACGGCAGTGAAGTGGTC
GAAACCCTTTTTGAAGTTACGGGTATCATTCGCTATGTTGCCTTTGGGCTTATGCTGGCATTGGCTTTTACAGCAACTTT
CTTGATTTCTAATACTATTAAGTTAACTGTTTATGCCCGTAGTGAAGAGATTAAGATAATGAAGCTGGTAGGAGCTACCA
ATTGGTTTATCAGGTGGCCGTTCCTTCTAGAAGGTTTATTGCTTGGGTTTTTAGGTTCTGCCATACCAGTAGTGATTTTG
AGATATGGTTACAGTTACTTGAGCGAATGGGTTTACAGCAATGCCGGTTTTATCAATTTACAACCACCAGAGGCTATTTT
TGAAAGTATGGATATTGCCTTGATCCTTCTAGGGACCTTTTTGGGAGCTTTAGGTAGTATTGCATCTTTAAGGCGATTTT
TGCGAGTTTAA

Upstream 100 bases:

>100_bases
GCGACTCACGACCGTGAAATTGTAGATCGGTTAAAACAACGAGTAGTTAGAATCGACGACGGCCAAATAGTCCGGGATAT
GGTAAGGGGTGGTTATGGTT

Downstream 100 bases:

>100_bases
AAATCATACAATCAGCTTATCAAAAAAGCGGGAAAGTAAAGGGGGCACGCCGGGGTGAATAATTTTAAATGCAGTAGCAT
CAAACATCGTAGGGACAGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKFRSWAYFFSEAFKSVFRNGWMSLASIGVVTVTLLMLGVFMIINQNVEYITEEVRGQVEIAVWLEDDLSSRDHDDIRTS
LIKISGVEKVKFVSQEEGLDRMKEQMGESAVQGYYDEPDQNPLPDMFEVNTVYPEDVPRVADEISQISGVDMVDYGSEVV
ETLFEVTGIIRYVAFGLMLALAFTATFLISNTIKLTVYARSEEIKIMKLVGATNWFIRWPFLLEGLLLGFLGSAIPVVIL
RYGYSYLSEWVYSNAGFINLQPPEAIFESMDIALILLGTFLGALGSIASLRRFLRV

Sequences:

>Translated_296_residues
MKFRSWAYFFSEAFKSVFRNGWMSLASIGVVTVTLLMLGVFMIINQNVEYITEEVRGQVEIAVWLEDDLSSRDHDDIRTS
LIKISGVEKVKFVSQEEGLDRMKEQMGESAVQGYYDEPDQNPLPDMFEVNTVYPEDVPRVADEISQISGVDMVDYGSEVV
ETLFEVTGIIRYVAFGLMLALAFTATFLISNTIKLTVYARSEEIKIMKLVGATNWFIRWPFLLEGLLLGFLGSAIPVVIL
RYGYSYLSEWVYSNAGFINLQPPEAIFESMDIALILLGTFLGALGSIASLRRFLRV
>Mature_296_residues
MKFRSWAYFFSEAFKSVFRNGWMSLASIGVVTVTLLMLGVFMIINQNVEYITEEVRGQVEIAVWLEDDLSSRDHDDIRTS
LIKISGVEKVKFVSQEEGLDRMKEQMGESAVQGYYDEPDQNPLPDMFEVNTVYPEDVPRVADEISQISGVDMVDYGSEVV
ETLFEVTGIIRYVAFGLMLALAFTATFLISNTIKLTVYARSEEIKIMKLVGATNWFIRWPFLLEGLLLGFLGSAIPVVIL
RYGYSYLSEWVYSNAGFINLQPPEAIFESMDIALILLGTFLGALGSIASLRRFLRV

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=234, Percent_Identity=29.4871794871795, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 33453; Mature: 33453

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRSWAYFFSEAFKSVFRNGWMSLASIGVVTVTLLMLGVFMIINQNVEYITEEVRGQVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEE
IAVWLEDDLSSRDHDDIRTSLIKISGVEKVKFVSQEEGLDRMKEQMGESAVQGYYDEPDQ
EEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCC
NPLPDMFEVNTVYPEDVPRVADEISQISGVDMVDYGSEVVETLFEVTGIIRYVAFGLMLA
CCCCCHHCCCCCCCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LAFTATFLISNTIKLTVYARSEEIKIMKLVGATNWFIRWPFLLEGLLLGFLGSAIPVVIL
HHHHHHHHHHCCEEEEEEECCCCEEEEEHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
RYGYSYLSEWVYSNAGFINLQPPEAIFESMDIALILLGTFLGALGSIASLRRFLRV
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFRSWAYFFSEAFKSVFRNGWMSLASIGVVTVTLLMLGVFMIINQNVEYITEEVRGQVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEE
IAVWLEDDLSSRDHDDIRTSLIKISGVEKVKFVSQEEGLDRMKEQMGESAVQGYYDEPDQ
EEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCC
NPLPDMFEVNTVYPEDVPRVADEISQISGVDMVDYGSEVVETLFEVTGIIRYVAFGLMLA
CCCCCHHCCCCCCCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LAFTATFLISNTIKLTVYARSEEIKIMKLVGATNWFIRWPFLLEGLLLGFLGSAIPVVIL
HHHHHHHHHHCCEEEEEEECCCCEEEEEHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
RYGYSYLSEWVYSNAGFINLQPPEAIFESMDIALILLGTFLGALGSIASLRRFLRV
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]