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The map label for this gene is 188586582

Identifier: 188586582

GI number: 188586582

Start: 2076806

End: 2077627

Strand: Direct

Name: 188586582

Synonym: Nther_1969

Alternate gene names: NA

Gene position: 2076806-2077627 (Clockwise)

Preceding gene: 188586581

Following gene: 188586583

Centisome position: 65.61

GC content: 37.47

Gene sequence:

>822_bases
ATGGAAGGAGGTTTTGAAAAAATGAATTTATTTAAAGAACAACTAGCGCCATTAACCAACGCCGCCTGGAATGAAATTAA
TGACCGAGCTGCTCAAGTAATTAAATCCAATTTATCCACCAGAAAAGTGTTTAAAATTAATGGTCCTAAAGGTTTAGATT
ACCCAGCTGTTTCTGAAGGAAGGTTAAGTGAAATTTTTCATGGACATCAACAAGGTGAGGTCAAAGCTGGACTACATCAA
GTCAAACCCCTTATGGAAACAAGAATCACTTTTAAACTCGATCGGTGGGAACTTGACAATATTGAAAGAGGTGCACAAGA
TATTGACCTAGAACCTCTAGAAGATGCAGCGAGAAAGATCGCCCTTTTTGAAGAAAACGCCATCTACAATGGGCATAACG
ATGGTCAAATTCCAGGTCTAAAAACTGTCTTAACTCAGGATTTGATTCCTCTTGGTAACACAGGTAGTGAAATCATGGAG
TCCATTACTAGAGGGATAATAACCTTGAGAAAAGCTTACATCTCTCAAAACATGACATTGATAGTTGGAGAGGAAGCCTG
GAGAAAAATTAATAAAGAAATGTCAGGAGAGCCATTAATAGAAAGAATTCATGAATTAACGGGCTCTAAAGTAGTTATCA
GTCCAATTGTTGACGGTGCATACCTTGTACCTTATGACCATGATGATCTGGAACTGACAATTGGCCTGGACTTCTCTATT
GGATATGAACATCATGATGAACACCATGTTCAGCTATTTATTACTGAGTCCTTTACATTCAGAGTCCTTGATCCAGATAC
AATCGTAAAATTTACATTATAA

Upstream 100 bases:

>100_bases
CTGATATACCCATAGCGGAAGCTGAAAAACGAGGTAATTTAGACCATGGAACCGATAAAAATGATCATCCTAATGGTCTA
ACAATCGGAGATATGAAGTA

Downstream 100 bases:

>100_bases
GGGAAAGCTCAAACTAATTGCAGGAGGCGGTTTGAAAATCCGTCTCCTGTAAAGCTTTATCTTTTCTCTAGATTACATTT
TTGTTTATAGATGATATAAT

Product: Linocin_M18 bacteriocin protein

Products: NA

Alternate protein names: Thermotoga bacteriocin [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MEGGFEKMNLFKEQLAPLTNAAWNEINDRAAQVIKSNLSTRKVFKINGPKGLDYPAVSEGRLSEIFHGHQQGEVKAGLHQ
VKPLMETRITFKLDRWELDNIERGAQDIDLEPLEDAARKIALFEENAIYNGHNDGQIPGLKTVLTQDLIPLGNTGSEIME
SITRGIITLRKAYISQNMTLIVGEEAWRKINKEMSGEPLIERIHELTGSKVVISPIVDGAYLVPYDHDDLELTIGLDFSI
GYEHHDEHHVQLFITESFTFRVLDPDTIVKFTL

Sequences:

>Translated_273_residues
MEGGFEKMNLFKEQLAPLTNAAWNEINDRAAQVIKSNLSTRKVFKINGPKGLDYPAVSEGRLSEIFHGHQQGEVKAGLHQ
VKPLMETRITFKLDRWELDNIERGAQDIDLEPLEDAARKIALFEENAIYNGHNDGQIPGLKTVLTQDLIPLGNTGSEIME
SITRGIITLRKAYISQNMTLIVGEEAWRKINKEMSGEPLIERIHELTGSKVVISPIVDGAYLVPYDHDDLELTIGLDFSI
GYEHHDEHHVQLFITESFTFRVLDPDTIVKFTL
>Mature_273_residues
MEGGFEKMNLFKEQLAPLTNAAWNEINDRAAQVIKSNLSTRKVFKINGPKGLDYPAVSEGRLSEIFHGHQQGEVKAGLHQ
VKPLMETRITFKLDRWELDNIERGAQDIDLEPLEDAARKIALFEENAIYNGHNDGQIPGLKTVLTQDLIPLGNTGSEIME
SITRGIITLRKAYISQNMTLIVGEEAWRKINKEMSGEPLIERIHELTGSKVVISPIVDGAYLVPYDHDDLELTIGLDFSI
GYEHHDEHHVQLFITESFTFRVLDPDTIVKFTL

Specific function: Protease that exhibits activity toward chymotrypsin and trypsin substrates. May have antibacterial activity [H]

COG id: COG1659

COG function: function code S; Uncharacterized protein, linocin/CFP29 homolog

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007544 [H]

Pfam domain/function: PF04454 Linocin_M18 [H]

EC number: NA

Molecular weight: Translated: 30830; Mature: 30830

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGGFEKMNLFKEQLAPLTNAAWNEINDRAAQVIKSNLSTRKVFKINGPKGLDYPAVSEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
RLSEIFHGHQQGEVKAGLHQVKPLMETRITFKLDRWELDNIERGAQDIDLEPLEDAARKI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEECCEECCCHHCCCCCCCCCCHHHHHHHH
ALFEENAIYNGHNDGQIPGLKTVLTQDLIPLGNTGSEIMESITRGIITLRKAYISQNMTL
HHEECCCEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
IVGEEAWRKINKEMSGEPLIERIHELTGSKVVISPIVDGAYLVPYDHDDLELTIGLDFSI
EECHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCEEEEEEEEEEE
GYEHHDEHHVQLFITESFTFRVLDPDTIVKFTL
CCCCCCCCEEEEEEECCEEEEEECCCCEEEEEC
>Mature Secondary Structure
MEGGFEKMNLFKEQLAPLTNAAWNEINDRAAQVIKSNLSTRKVFKINGPKGLDYPAVSEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
RLSEIFHGHQQGEVKAGLHQVKPLMETRITFKLDRWELDNIERGAQDIDLEPLEDAARKI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEECCEECCCHHCCCCCCCCCCHHHHHHHH
ALFEENAIYNGHNDGQIPGLKTVLTQDLIPLGNTGSEIMESITRGIITLRKAYISQNMTL
HHEECCCEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
IVGEEAWRKINKEMSGEPLIERIHELTGSKVVISPIVDGAYLVPYDHDDLELTIGLDFSI
EECHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCEEEEEEEEEEE
GYEHHDEHHVQLFITESFTFRVLDPDTIVKFTL
CCCCCCCCEEEEEEECCEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]