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The map label for this gene is 188586101

Identifier: 188586101

GI number: 188586101

Start: 1547998

End: 1549461

Strand: Direct

Name: 188586101

Synonym: Nther_1475

Alternate gene names: NA

Gene position: 1547998-1549461 (Clockwise)

Preceding gene: 188586100

Following gene: 188586102

Centisome position: 48.9

GC content: 38.39

Gene sequence:

>1464_bases
ATGATCGCTGAAGCCAAAATAACCTCCGCTGAGGAGGCTGCCGATAAAATCATCGAAGATGCCAAAAAGCAAGGAGAGTC
TATGAAAAGAGAAGCTCTTCTTGAGGCAAAAGAAGAAATCCACACTCAAAGAAATGAACTTGAAAAGGAAACTCGTGAAA
GAAGAAATGAAATCCAAAGATTTGAAAGAAAGCTAGAACAAAAGGAAGAATCTCTTTCTAAACAACAGAAACAATTAGAA
CAAAAAGAAAAAGAGATTGCCCAAAAAGACGAAAAAATCACTAATAAGGAACAAGAATTAGAGAAAATTTATCAACAACA
GGTAGAGGAACTTGAAAACTTGTCTGGACTAACTACTCAAGAAGCAAAAGACATGCTATTGAATAGAGTTAGGGAAGACA
TAAGCCATGAAACGGCTATGATGATTAAAGAGATGGAAAGCCGTGCCAAGGAAGAGGCTGATAAAAAGGCCAGAGAAATT
ATTACTACAGCAATTCAAAGATGTGCTGTTGACCATGTAGCCGAGTCTACAGTATCCGTAGTTTCATTGCCCAATGATGA
AATGAAAGGTAGAATCATAGGCCGAGAAGGCCGTAATATCAGAACATTAGAGACTTTAACTGGTATTGATTTGATCATAG
ATGATACACCTGAAGCCGTTATTCTATCAGGATTTGATCCCATCCGACGTGAAATTGCTAGACTGGCACTAGAGAAATTG
GTGTCTGATGGGCGTATTCATCCCGCTCGAATAGAGGAAATGGTAGAAAAAGCTCAAAAAGAAGTAGATGAGCAAATAAG
AGAAGAAGGTGAACAAGCTACCTTAGATACAGGAGTACATGGATTACATTCCGAGCTAATTAAATTACTTGGAAGATTAA
AATTCAGAACCAGCTATGGTCAAAATGTCCTTAATCACTCTATTGAAGTTGCTCGCCTGTGTGGCGTAATGGCTCACGAG
TTGGGAACCGATGTAAATACGGCCAAAAGAGCCGGGTTACTTCACGATATTGGTAAAGCTGTAGATCATGAATATGAAGG
TCCTCATGTCACGATAGGTGCCGAATTAGGTAAAAAATACGGTGAATCATCTAATGTATTACATGCCATTGCAACTCATC
ACGGTGATGAAGAACCGGAAACAATCGAAGCAGTGTTAGTACAAGCAGCTGATGCTATTTCAGCCGCTAGACCAGGTGCT
AGAAGAGAAACTCTAGAATCTTATATTAAGAGACTTGAGAAATTAGAAGAGATAGCAGACTCTTATAAAAGTGTTGAAAA
AGCATATGCAATTCAAGCTGGTCGGGAAGTTAGAATTATGGTTAAACCCGAACAGGCCGATGATGAAACAAGTATTAACT
TAGCACGTGATATTTCTAAACAAATTGAAGCAGAACTAGACTATCCTGGACAGATAAAAATAACCGTAATAAGAGAAACC
AGAGCTGTAGAATATGCTAAATAA

Upstream 100 bases:

>100_bases
GAAGCAGGAGGTGAGTTAAATTAACGGTTTAATCAATATACTGTTACCAGTAGTAGGTGCAGGAGCAACAGGAATATTAG
TCGGCTATTTAGTGAGAAAA

Downstream 100 bases:

>100_bases
ATCATGCATATATAAGTGTCCCTTCGGGGACACTTATTGTATTTGGATTATTTTAGGAGGATTTAGGAGGATATGAATAT
GAAAGATGTAAAAGTGCTAA

Product: metal dependent phosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MIAEAKITSAEEAADKIIEDAKKQGESMKREALLEAKEEIHTQRNELEKETRERRNEIQRFERKLEQKEESLSKQQKQLE
QKEKEIAQKDEKITNKEQELEKIYQQQVEELENLSGLTTQEAKDMLLNRVREDISHETAMMIKEMESRAKEEADKKAREI
ITTAIQRCAVDHVAESTVSVVSLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARLALEKL
VSDGRIHPARIEEMVEKAQKEVDEQIREEGEQATLDTGVHGLHSELIKLLGRLKFRTSYGQNVLNHSIEVARLCGVMAHE
LGTDVNTAKRAGLLHDIGKAVDHEYEGPHVTIGAELGKKYGESSNVLHAIATHHGDEEPETIEAVLVQAADAISAARPGA
RRETLESYIKRLEKLEEIADSYKSVEKAYAIQAGREVRIMVKPEQADDETSINLARDISKQIEAELDYPGQIKITVIRET
RAVEYAK

Sequences:

>Translated_487_residues
MIAEAKITSAEEAADKIIEDAKKQGESMKREALLEAKEEIHTQRNELEKETRERRNEIQRFERKLEQKEESLSKQQKQLE
QKEKEIAQKDEKITNKEQELEKIYQQQVEELENLSGLTTQEAKDMLLNRVREDISHETAMMIKEMESRAKEEADKKAREI
ITTAIQRCAVDHVAESTVSVVSLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARLALEKL
VSDGRIHPARIEEMVEKAQKEVDEQIREEGEQATLDTGVHGLHSELIKLLGRLKFRTSYGQNVLNHSIEVARLCGVMAHE
LGTDVNTAKRAGLLHDIGKAVDHEYEGPHVTIGAELGKKYGESSNVLHAIATHHGDEEPETIEAVLVQAADAISAARPGA
RRETLESYIKRLEKLEEIADSYKSVEKAYAIQAGREVRIMVKPEQADDETSINLARDISKQIEAELDYPGQIKITVIRET
RAVEYAK
>Mature_487_residues
MIAEAKITSAEEAADKIIEDAKKQGESMKREALLEAKEEIHTQRNELEKETRERRNEIQRFERKLEQKEESLSKQQKQLE
QKEKEIAQKDEKITNKEQELEKIYQQQVEELENLSGLTTQEAKDMLLNRVREDISHETAMMIKEMESRAKEEADKKAREI
ITTAIQRCAVDHVAESTVSVVSLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARLALEKL
VSDGRIHPARIEEMVEKAQKEVDEQIREEGEQATLDTGVHGLHSELIKLLGRLKFRTSYGQNVLNHSIEVARLCGVMAHE
LGTDVNTAKRAGLLHDIGKAVDHEYEGPHVTIGAELGKKYGESSNVLHAIATHHGDEEPETIEAVLVQAADAISAARPGA
RRETLESYIKRLEKLEEIADSYKSVEKAYAIQAGREVRIMVKPEQADDETSINLARDISKQIEAELDYPGQIKITVIRET
RAVEYAK

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_NATTJ (B2A3V6)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001917646.1
- ProteinModelPortal:   B2A3V6
- SMR:   B2A3V6
- GeneID:   6315476
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_1475
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- GO:   GO:0016020
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 55095; Mature: 55095

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAEAKITSAEEAADKIIEDAKKQGESMKREALLEAKEEIHTQRNELEKETRERRNEIQR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FERKLEQKEESLSKQQKQLEQKEKEIAQKDEKITNKEQELEKIYQQQVEELENLSGLTTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHH
EAKDMLLNRVREDISHETAMMIKEMESRAKEEADKKAREIITTAIQRCAVDHVAESTVSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARLALEKL
HCCCCHHHCCCEECCCCCCCCHHHHHCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHH
VSDGRIHPARIEEMVEKAQKEVDEQIREEGEQATLDTGVHGLHSELIKLLGRLKFRTSYG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNVLNHSIEVARLCGVMAHELGTDVNTAKRAGLLHDIGKAVDHEYEGPHVTIGAELGKKY
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHH
GESSNVLHAIATHHGDEEPETIEAVLVQAADAISAARPGARRETLESYIKRLEKLEEIAD
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SYKSVEKAYAIQAGREVRIMVKPEQADDETSINLARDISKQIEAELDYPGQIKITVIRET
HHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
RAVEYAK
CHHCCCC
>Mature Secondary Structure
MIAEAKITSAEEAADKIIEDAKKQGESMKREALLEAKEEIHTQRNELEKETRERRNEIQR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FERKLEQKEESLSKQQKQLEQKEKEIAQKDEKITNKEQELEKIYQQQVEELENLSGLTTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHH
EAKDMLLNRVREDISHETAMMIKEMESRAKEEADKKAREIITTAIQRCAVDHVAESTVSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARLALEKL
HCCCCHHHCCCEECCCCCCCCHHHHHCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHH
VSDGRIHPARIEEMVEKAQKEVDEQIREEGEQATLDTGVHGLHSELIKLLGRLKFRTSYG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNVLNHSIEVARLCGVMAHELGTDVNTAKRAGLLHDIGKAVDHEYEGPHVTIGAELGKKY
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHH
GESSNVLHAIATHHGDEEPETIEAVLVQAADAISAARPGARRETLESYIKRLEKLEEIAD
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SYKSVEKAYAIQAGREVRIMVKPEQADDETSINLARDISKQIEAELDYPGQIKITVIRET
HHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
RAVEYAK
CHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA