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The map label for this gene is cheA [H]

Identifier: 188586044

GI number: 188586044

Start: 1487833

End: 1489974

Strand: Direct

Name: cheA [H]

Synonym: Nther_1418

Alternate gene names: 188586044

Gene position: 1487833-1489974 (Clockwise)

Preceding gene: 188586043

Following gene: 188586045

Centisome position: 47.0

GC content: 35.99

Gene sequence:

>2142_bases
ATGGATAATCAATATCTTGATGTTTTTATTGATGAAGCGAGAGAACATTTACAAACCATGAATCAAAATTTGATTGATCT
GGAACAAAGTCCTGAGGATCGATCTATTTTAGATTCTTTGTTTAGGGTTGCTCATACATTAAAAGGGATGGCAGCCACTA
TGGGGTATCAAGGAGTTGCAAATTACACCCATAAATTAGAAAATATCCTGGATAGTTTTCGCCAAGGTGAGAAAAAGATT
ACATCGAACATTATTGATTTATTGTTAGAAGGAGCCGATGCCCTAGAAGAATTCGTAAATAAATTGTCAGAAGGTGAACA
AGTAGATCTAGATTTTAGTAGTATGCAGTCACGCCTAGAACAAGCTTTTGCTAAGGCGGACAGAGATTCTTTTGAGACTC
CTTCCCAGGCACAAGATACTTCTTCTACTAATAATGAACAGTCCAAGGGAGAAGCTGAAATGGCTGCAACTAGTGAAGTT
CAGACTGACTCTTCAGGGGAAAAGGCAGGATCAGAAAGTGATATTTTAGATTTAAATGAATATGAAGGAAACTTGTTAAA
ATCGGCTTTAAACGACGATTATTCGGCCTATCACATTAGAGTTGTTTTTGATGAAAATGTACTTTTAAAAGGTGCTAGAG
CTTTTATGGTATTTCAAAAAGTAGAAGCTAGAGGAGAAATCATTAAATCTGACCCAGAAGTTGAAGAAATTGAAGATGAG
AACTTTGATCAGGAAATTGAACTGATAGTGGTAACCAAGGTTGATCAGCAAGAAATAAAGTCGGATATTGAACAGGTTTC
AGAAATAAATGAAGTTTACCTAAAAGTACTCCAAGAGGATCAACTTACAGATAAAACAGACGAAGGAGCAGATGAAGACG
ATGATGAGAAAGTTCAGACAGAAGAACAGAAAGTTCAACAAAAAGACAAACAAGATGAAGCCAAAGATTCAGATGGACAA
AGCCAGCAAAAGATTAAGACTGGAAAGACCGTCAGAGTAGATATTGAGCGATTGGACAAGTTAATGAATTTAGTAAGTGA
ACTCGTTATTAACAAGACTCGCTTAGAACAGGTAGCAAATAACAAAGAATCCTCTGAACTTGGAAAAACTAGTGAACAAT
TTAGTAGAATTACCAGTGAAATTCAAAATGTAGTGATGAAAGTTAGAATGGTTCCTTTAGACCAGGTTTTTAACCGTTTC
CCAAGAATGGTAAGGGATCTATCAAGATCCTTAAATAAAGAAGTTAATTTAGTCATTGAAGGAAGGGAAACAGAGTTAGA
TCGATCTTTGATAGATGAGATCGGTGACTTATTAATGCATTTAATAAGAAATGCTCTAGACCATGGTCTAGAAGATTCTG
AAACCAGACATAAATCGGGGAAATCAGCCAAGGGAAATATTCATATTAAAGCTTATCACAACGAAAACAATGTAGTTATT
GAAGTCTCAGATGATGGTAAGGGAATTGATCCAGAAAAAGTAAGGAAAAAAGCAATTTCCAGAGGATTGCTCGATAGCCA
ACAAAGTGAACAAGTGCCTGATTCAGAAGTGATTAACTTTTTATTCACTCCAGGGTTTAGTACATCTGATGAGGTCTCCG
AGGTATCTGGTAGGGGAGTTGGCCTGGACGTGGTCAAAAGTAAACTTGAAAATCTTGGTGGACGCGTGGAGTTAGACAGT
GAAATTAATCAAGGCACAAAATTCACTATGTATTTACCTTTAACTCTAGCTATAATCCAGGCATTAATGGTCAATGTAGG
CAATGAGCAATATGCTTTACCATTGTCATCCATTGAAGAAACGACAATTTTAACAGATCAGGATATCCAAAAGGTTCAAG
AACAAGAAGTTATCAGGTTAAGGGATCAATTGGTACCTCTAATTGATCTGCACGACATTTTAGATGTTGAACGTACTGAA
AATGGCGAACAAGAGCATGCTGAACAAGAAAGATTTGCTATTATAGTTAGAAAAGGCGATAAAAAGGCAGGATTAATAGT
TGATGAACTACTGGGACAGCAAGAAGTTGTAATAAAGTCTCTAGGTGGCTTTTTGGCCGATATTAAAGGGTTTACAGGAG
CAACAATTTTAGGTGATGGAAAAGTTGCTTTAATTTTAGATGTGAATTCATTATTATTTTAA

Upstream 100 bases:

>100_bases
CAGCTATAAATACCGGCCTAGTAGATAAAATTTTACCTTTACCCGCAATTGCTCCAGAGATACTGAATGTGATTACCTAA
ATTGTTTGGGGGTGGATTAA

Downstream 100 bases:

>100_bases
AGGAGGATGGTAAATATGACTGAAACTCAAGCTACTACGGGAGATCAACAGTACATTGTGTTTAATCTAGGAGATGAGGA
ATATGGAGTAGAGATTCTTC

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 713

Protein sequence:

>713_residues
MDNQYLDVFIDEAREHLQTMNQNLIDLEQSPEDRSILDSLFRVAHTLKGMAATMGYQGVANYTHKLENILDSFRQGEKKI
TSNIIDLLLEGADALEEFVNKLSEGEQVDLDFSSMQSRLEQAFAKADRDSFETPSQAQDTSSTNNEQSKGEAEMAATSEV
QTDSSGEKAGSESDILDLNEYEGNLLKSALNDDYSAYHIRVVFDENVLLKGARAFMVFQKVEARGEIIKSDPEVEEIEDE
NFDQEIELIVVTKVDQQEIKSDIEQVSEINEVYLKVLQEDQLTDKTDEGADEDDDEKVQTEEQKVQQKDKQDEAKDSDGQ
SQQKIKTGKTVRVDIERLDKLMNLVSELVINKTRLEQVANNKESSELGKTSEQFSRITSEIQNVVMKVRMVPLDQVFNRF
PRMVRDLSRSLNKEVNLVIEGRETELDRSLIDEIGDLLMHLIRNALDHGLEDSETRHKSGKSAKGNIHIKAYHNENNVVI
EVSDDGKGIDPEKVRKKAISRGLLDSQQSEQVPDSEVINFLFTPGFSTSDEVSEVSGRGVGLDVVKSKLENLGGRVELDS
EINQGTKFTMYLPLTLAIIQALMVNVGNEQYALPLSSIEETTILTDQDIQKVQEQEVIRLRDQLVPLIDLHDILDVERTE
NGEQEHAEQERFAIIVRKGDKKAGLIVDELLGQQEVVIKSLGGFLADIKGFTGATILGDGKVALILDVNSLLF

Sequences:

>Translated_713_residues
MDNQYLDVFIDEAREHLQTMNQNLIDLEQSPEDRSILDSLFRVAHTLKGMAATMGYQGVANYTHKLENILDSFRQGEKKI
TSNIIDLLLEGADALEEFVNKLSEGEQVDLDFSSMQSRLEQAFAKADRDSFETPSQAQDTSSTNNEQSKGEAEMAATSEV
QTDSSGEKAGSESDILDLNEYEGNLLKSALNDDYSAYHIRVVFDENVLLKGARAFMVFQKVEARGEIIKSDPEVEEIEDE
NFDQEIELIVVTKVDQQEIKSDIEQVSEINEVYLKVLQEDQLTDKTDEGADEDDDEKVQTEEQKVQQKDKQDEAKDSDGQ
SQQKIKTGKTVRVDIERLDKLMNLVSELVINKTRLEQVANNKESSELGKTSEQFSRITSEIQNVVMKVRMVPLDQVFNRF
PRMVRDLSRSLNKEVNLVIEGRETELDRSLIDEIGDLLMHLIRNALDHGLEDSETRHKSGKSAKGNIHIKAYHNENNVVI
EVSDDGKGIDPEKVRKKAISRGLLDSQQSEQVPDSEVINFLFTPGFSTSDEVSEVSGRGVGLDVVKSKLENLGGRVELDS
EINQGTKFTMYLPLTLAIIQALMVNVGNEQYALPLSSIEETTILTDQDIQKVQEQEVIRLRDQLVPLIDLHDILDVERTE
NGEQEHAEQERFAIIVRKGDKKAGLIVDELLGQQEVVIKSLGGFLADIKGFTGATILGDGKVALILDVNSLLF
>Mature_713_residues
MDNQYLDVFIDEAREHLQTMNQNLIDLEQSPEDRSILDSLFRVAHTLKGMAATMGYQGVANYTHKLENILDSFRQGEKKI
TSNIIDLLLEGADALEEFVNKLSEGEQVDLDFSSMQSRLEQAFAKADRDSFETPSQAQDTSSTNNEQSKGEAEMAATSEV
QTDSSGEKAGSESDILDLNEYEGNLLKSALNDDYSAYHIRVVFDENVLLKGARAFMVFQKVEARGEIIKSDPEVEEIEDE
NFDQEIELIVVTKVDQQEIKSDIEQVSEINEVYLKVLQEDQLTDKTDEGADEDDDEKVQTEEQKVQQKDKQDEAKDSDGQ
SQQKIKTGKTVRVDIERLDKLMNLVSELVINKTRLEQVANNKESSELGKTSEQFSRITSEIQNVVMKVRMVPLDQVFNRF
PRMVRDLSRSLNKEVNLVIEGRETELDRSLIDEIGDLLMHLIRNALDHGLEDSETRHKSGKSAKGNIHIKAYHNENNVVI
EVSDDGKGIDPEKVRKKAISRGLLDSQQSEQVPDSEVINFLFTPGFSTSDEVSEVSGRGVGLDVVKSKLENLGGRVELDS
EINQGTKFTMYLPLTLAIIQALMVNVGNEQYALPLSSIEETTILTDQDIQKVQEQEVIRLRDQLVPLIDLHDILDVERTE
NGEQEHAEQERFAIIVRKGDKKAGLIVDELLGQQEVVIKSLGGFLADIKGFTGATILGDGKVALILDVNSLLF

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Membrane (Potential). Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=715, Percent_Identity=32.8671328671329, Blast_Score=352, Evalue=5e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80026; Mature: 80026

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNQYLDVFIDEAREHLQTMNQNLIDLEQSPEDRSILDSLFRVAHTLKGMAATMGYQGVA
CCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NYTHKLENILDSFRQGEKKITSNIIDLLLEGADALEEFVNKLSEGEQVDLDFSSMQSRLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEECCCHHHHHHHHH
QAFAKADRDSFETPSQAQDTSSTNNEQSKGEAEMAATSEVQTDSSGEKAGSESDILDLNE
HHHHHCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
YEGNLLKSALNDDYSAYHIRVVFDENVLLKGARAFMVFQKVEARGEIIKSDPEVEEIEDE
HHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHCCC
NFDQEIELIVVTKVDQQEIKSDIEQVSEINEVYLKVLQEDQLTDKTDEGADEDDDEKVQT
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
EEQKVQQKDKQDEAKDSDGQSQQKIKTGKTVRVDIERLDKLMNLVSELVINKTRLEQVAN
HHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
NKESSELGKTSEQFSRITSEIQNVVMKVRMVPLDQVFNRFPRMVRDLSRSLNKEVNLVIE
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
GRETELDRSLIDEIGDLLMHLIRNALDHGLEDSETRHKSGKSAKGNIHIKAYHNENNVVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEEEECCCCEEE
EVSDDGKGIDPEKVRKKAISRGLLDSQQSEQVPDSEVINFLFTPGFSTSDEVSEVSGRGV
EECCCCCCCCHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCC
GLDVVKSKLENLGGRVELDSEINQGTKFTMYLPLTLAIIQALMVNVGNEQYALPLSSIEE
CHHHHHHHHHHCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCEECCHHHCCH
TTILTDQDIQKVQEQEVIRLRDQLVPLIDLHDILDVERTENGEQEHAEQERFAIIVRKGD
HHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHEEEEEEECC
KKAGLIVDELLGQQEVVIKSLGGFLADIKGFTGATILGDGKVALILDVNSLLF
CCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECHHHCC
>Mature Secondary Structure
MDNQYLDVFIDEAREHLQTMNQNLIDLEQSPEDRSILDSLFRVAHTLKGMAATMGYQGVA
CCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NYTHKLENILDSFRQGEKKITSNIIDLLLEGADALEEFVNKLSEGEQVDLDFSSMQSRLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEECCCHHHHHHHHH
QAFAKADRDSFETPSQAQDTSSTNNEQSKGEAEMAATSEVQTDSSGEKAGSESDILDLNE
HHHHHCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
YEGNLLKSALNDDYSAYHIRVVFDENVLLKGARAFMVFQKVEARGEIIKSDPEVEEIEDE
HHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHCCC
NFDQEIELIVVTKVDQQEIKSDIEQVSEINEVYLKVLQEDQLTDKTDEGADEDDDEKVQT
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
EEQKVQQKDKQDEAKDSDGQSQQKIKTGKTVRVDIERLDKLMNLVSELVINKTRLEQVAN
HHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
NKESSELGKTSEQFSRITSEIQNVVMKVRMVPLDQVFNRFPRMVRDLSRSLNKEVNLVIE
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
GRETELDRSLIDEIGDLLMHLIRNALDHGLEDSETRHKSGKSAKGNIHIKAYHNENNVVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEEEECCCCEEE
EVSDDGKGIDPEKVRKKAISRGLLDSQQSEQVPDSEVINFLFTPGFSTSDEVSEVSGRGV
EECCCCCCCCHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCC
GLDVVKSKLENLGGRVELDSEINQGTKFTMYLPLTLAIIQALMVNVGNEQYALPLSSIEE
CHHHHHHHHHHCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCEECCHHHCCH
TTILTDQDIQKVQEQEVIRLRDQLVPLIDLHDILDVERTENGEQEHAEQERFAIIVRKGD
HHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHEEEEEEECC
KKAGLIVDELLGQQEVVIKSLGGFLADIKGFTGATILGDGKVALILDVNSLLF
CCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1938941; 9384377 [H]