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The map label for this gene is fliY [H]

Identifier: 188586032

GI number: 188586032

Start: 1476392

End: 1477660

Strand: Direct

Name: fliY [H]

Synonym: Nther_1406

Alternate gene names: 188586032

Gene position: 1476392-1477660 (Clockwise)

Preceding gene: 188586031

Following gene: 188586033

Centisome position: 46.64

GC content: 39.87

Gene sequence:

>1269_bases
TTGGAGAATAATAAAGATATCTTGTCCCAAGAAGAAATTGATGCTCTGTTAAAAGGATCAGGCGACGATGATAGTGGCGA
TGATGGAGATAACCATGGTGGTAGTGGCGGCAGCGGATCAGGTAACGATGGCAATGGAGGTAATGGAAATAATGGAGATA
ATGGTGATAATTCTTTAAATGAAACTGAAAAGGATACCGTTGGTGAAATTGGAAACATTTCCATGGGGACTGCTGCTACT
ACCTTATCAGTACTACTTAATCAGAAAGTATCTATAACTACTCCAAGAGTTGAAGTGACAGACTATGCCACTTTAAGAGA
AGAATTTCCTAAACCTCATGTAGCAGTAGAAGTGGAATACTTGGAGGGGCTTGAAGGAATTAATGTATTAATCCTAAAAC
AAGAGGATGCAAAAATGATTGCCAATTTAATGATGGGTGGCGACGGTACAGATATTGCTGAAGGTGAAATCGAGGAATTT
CACTTAAGTGCTGTAGGAGAAGCCATGAATCAGATGATGGGCTCGGCCTCGACTTCCATGTCTGATATGTTTGATAAAAC
CATTAATATTTCGCCTCCAAGTGTAAAAATGCTGGATCTAGGATCTGAAGAAGCCCTAGAAGAACTTCCAAAAGAGCCCA
TGATTAAAGTTGCATTTGATTTAAAAATCGGTGATTTAATTGATAGCGAAATCATGCAGTTAATACCCTTTGAATTTGCT
AAAGATATGGTAGTTTCTTTAACTGGAGATAGTGCAGAAGAAGTTTCAGCAGGTCAACAAGAAATGGCTGCAAGTTCCGA
AGGAACAGCAGCTGCAAAACCCCAAGCTCCGACTCAAACTGGTCCTGGGCCAGAATCTGGTCAATCGCCAGAAAGGGAGG
TGTCTACACAAGGACAACCAACAGGACAAGGAGAGCAACAAATGAAACAAGAGCAACAGCCAAAGAAAGACTATCAACCT
GTAGAATTTTCGCCTTTAGAAGGTCATCAATCGGCTGCCAAAGGAGAAAATTCCAATATTGAATTGATAATGGATGTTCC
TCTGGAAGTAACGGTTGAACTGGGACAAACCAAGAAAAAAATCCAAGAAATATTGGAATTGGTTCCAGGATCTATTATAG
AACTGGATAAAATTGCCGGGGAGCCAGTTGATATAAAAGTTAATGGGAAATTAATCGCTAAAGGGGAAGTAGTTGTAATC
GATGAGAACTTCGGTATCAGAATTACCGAAATAATTAGTCCGGTGGAGAGGATTAACAAACTTCAGTAA

Upstream 100 bases:

>100_bases
ATAGTAGGAAAAAAGACGAAATTCAAGGGCAAACCTGGATCAATTAAAAATAAACTAGCTGTACAAATCACTCAAATAGT
TAGGGAAGGAGATGATTCCC

Downstream 100 bases:

>100_bases
AATTAAAAACGATAAAACTAGCTAAAAAGGGAGGGCTATGTACTGATGAGTCAAAAAGTTTTAATTGTAGATGATGCTGC
ATTTATGCGTATGATGATCA

Product: CheC, inhibitor of MCP methylation / FliN fusion protein

Products: NA

Alternate protein names: CheY-P phosphatase FliY [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MENNKDILSQEEIDALLKGSGDDDSGDDGDNHGGSGGSGSGNDGNGGNGNNGDNGDNSLNETEKDTVGEIGNISMGTAAT
TLSVLLNQKVSITTPRVEVTDYATLREEFPKPHVAVEVEYLEGLEGINVLILKQEDAKMIANLMMGGDGTDIAEGEIEEF
HLSAVGEAMNQMMGSASTSMSDMFDKTINISPPSVKMLDLGSEEALEELPKEPMIKVAFDLKIGDLIDSEIMQLIPFEFA
KDMVVSLTGDSAEEVSAGQQEMAASSEGTAAAKPQAPTQTGPGPESGQSPEREVSTQGQPTGQGEQQMKQEQQPKKDYQP
VEFSPLEGHQSAAKGENSNIELIMDVPLEVTVELGQTKKKIQEILELVPGSIIELDKIAGEPVDIKVNGKLIAKGEVVVI
DENFGIRITEIISPVERINKLQ

Sequences:

>Translated_422_residues
MENNKDILSQEEIDALLKGSGDDDSGDDGDNHGGSGGSGSGNDGNGGNGNNGDNGDNSLNETEKDTVGEIGNISMGTAAT
TLSVLLNQKVSITTPRVEVTDYATLREEFPKPHVAVEVEYLEGLEGINVLILKQEDAKMIANLMMGGDGTDIAEGEIEEF
HLSAVGEAMNQMMGSASTSMSDMFDKTINISPPSVKMLDLGSEEALEELPKEPMIKVAFDLKIGDLIDSEIMQLIPFEFA
KDMVVSLTGDSAEEVSAGQQEMAASSEGTAAAKPQAPTQTGPGPESGQSPEREVSTQGQPTGQGEQQMKQEQQPKKDYQP
VEFSPLEGHQSAAKGENSNIELIMDVPLEVTVELGQTKKKIQEILELVPGSIIELDKIAGEPVDIKVNGKLIAKGEVVVI
DENFGIRITEIISPVERINKLQ
>Mature_422_residues
MENNKDILSQEEIDALLKGSGDDDSGDDGDNHGGSGGSGSGNDGNGGNGNNGDNGDNSLNETEKDTVGEIGNISMGTAAT
TLSVLLNQKVSITTPRVEVTDYATLREEFPKPHVAVEVEYLEGLEGINVLILKQEDAKMIANLMMGGDGTDIAEGEIEEF
HLSAVGEAMNQMMGSASTSMSDMFDKTINISPPSVKMLDLGSEEALEELPKEPMIKVAFDLKIGDLIDSEIMQLIPFEFA
KDMVVSLTGDSAEEVSAGQQEMAASSEGTAAAKPQAPTQTGPGPESGQSPEREVSTQGQPTGQGEQQMKQEQQPKKDYQP
VEFSPLEGHQSAAKGENSNIELIMDVPLEVTVELGQTKKKIQEILELVPGSIIELDKIAGEPVDIKVNGKLIAKGEVVVI
DENFGIRITEIISPVERINKLQ

Specific function: Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attr

COG id: COG1776

COG function: function code NT; Chemotaxis protein CheC, inhibitor of MCP methylation

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=The switch is localized at the base of the flagellar motor, in or near the C-ring, attached to the MS-ring (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliN/MopA/SpaO family [H]

Homologues:

Organism=Escherichia coli, GI1788256, Length=87, Percent_Identity=54.0229885057471, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007597
- InterPro:   IPR012826
- InterPro:   IPR001172
- InterPro:   IPR001543 [H]

Pfam domain/function: PF04509 CheC; PF01052 SpoA [H]

EC number: NA

Molecular weight: Translated: 44927; Mature: 44927

Theoretical pI: Translated: 3.94; Mature: 3.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNKDILSQEEIDALLKGSGDDDSGDDGDNHGGSGGSGSGNDGNGGNGNNGDNGDNSLN
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ETEKDTVGEIGNISMGTAATTLSVLLNQKVSITTPRVEVTDYATLREEFPKPHVAVEVEY
CCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEECCCEEEHHHHHHHHHCCCCCEEEEEHH
LEGLEGINVLILKQEDAKMIANLMMGGDGTDIAEGEIEEFHLSAVGEAMNQMMGSASTSM
HCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHH
SDMFDKTINISPPSVKMLDLGSEEALEELPKEPMIKVAFDLKIGDLIDSEIMQLIPFEFA
HHHHHCCCCCCCCCEEEEECCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
KDMVVSLTGDSAEEVSAGQQEMAASSEGTAAAKPQAPTQTGPGPESGQSPEREVSTQGQP
CCEEEEECCCCHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCC
TGQGEQQMKQEQQPKKDYQPVEFSPLEGHQSAAKGENSNIELIMDVPLEVTVELGQTKKK
CCCCHHHHHHHHCCHHCCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCEEEEECCHHHHH
IQEILELVPGSIIELDKIAGEPVDIKVNGKLIAKGEVVVIDENFGIRITEIISPVERINK
HHHHHHHCCCCEEEHHHHCCCCEEEEECCEEEECCEEEEEECCCCEEHHHHHHHHHHHHC
LQ
CC
>Mature Secondary Structure
MENNKDILSQEEIDALLKGSGDDDSGDDGDNHGGSGGSGSGNDGNGGNGNNGDNGDNSLN
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ETEKDTVGEIGNISMGTAATTLSVLLNQKVSITTPRVEVTDYATLREEFPKPHVAVEVEY
CCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEECCCEEEHHHHHHHHHCCCCCEEEEEHH
LEGLEGINVLILKQEDAKMIANLMMGGDGTDIAEGEIEEFHLSAVGEAMNQMMGSASTSM
HCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHH
SDMFDKTINISPPSVKMLDLGSEEALEELPKEPMIKVAFDLKIGDLIDSEIMQLIPFEFA
HHHHHCCCCCCCCCEEEEECCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHH
KDMVVSLTGDSAEEVSAGQQEMAASSEGTAAAKPQAPTQTGPGPESGQSPEREVSTQGQP
CCEEEEECCCCHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCC
TGQGEQQMKQEQQPKKDYQPVEFSPLEGHQSAAKGENSNIELIMDVPLEVTVELGQTKKK
CCCCHHHHHHHHCCHHCCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCEEEEECCHHHHH
IQEILELVPGSIIELDKIAGEPVDIKVNGKLIAKGEVVVIDENFGIRITEIISPVERINK
HHHHHHHCCCCEEEHHHHCCCCEEEEECCEEEECCEEEEEECCCCEEHHHHHHHHHHHHC
LQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1447979; 9384377; 1898932 [H]