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The map label for this gene is fabF [H]

Identifier: 188585988

GI number: 188585988

Start: 1433247

End: 1434470

Strand: Direct

Name: fabF [H]

Synonym: Nther_1362

Alternate gene names: 188585988

Gene position: 1433247-1434470 (Clockwise)

Preceding gene: 188585987

Following gene: 188585989

Centisome position: 45.28

GC content: 40.28

Gene sequence:

>1224_bases
GTGACTGGCTTGGGAGTTATCAGTCCTAACGGTTTAGGTAAAGAACAGTTTTGGAATGCACTACAAAATGGGAGCAGCGG
AGTAGATGAAATCACATCTTTTGATACCGAAGAATTTTCAACAAAAATAGCTGGTGAAGTATTAGACTTTGAAGCCACAG
ACTTTTTTAGTAAAAAAGAAGCGAGGAGAATGGATAGGTTTGTTCAATTTGCGTCAGCTGCTAGTCAGATGGCTGTCGAT
GATGCAGCTCTTGAAATAACTGATGAATTGAAAAATTCAGTAGGAGTTTCTATAGGCTCAGGAATAGGTGGACTACAAAC
CTTAGAAGAAAGTCATAAAAAGCTAATGGAAAAAGGGCCTAAAAGAGTAAGCCCCTTATTTATTCCCATGATGATTGCTA
ATATGGCTTCGGGTAAGGTGTCAATAGATTTGGGTGCAAAAGGACCAAATTTGACTTTAGTAACTGCTTGTGCTACTGCT
GCTCATGCTATCGGTGAATCGCTCAGAATACTTCAAAGGGGTGAATGTGATGTGATGATCACCGGAGGATCTGAAGCGAC
TGTCACACCTTTAGCTATTGCAGGATTTGGTTCTATGAAGGCATTATCAACGCGAAATGACGATCCCCAAAAAGCAAGTC
GGCCCTTTGATAAAAATAGGGACGGATTTGTAATGGGAGAAGGAGCTGGAGTTTTAGTTCTGGAAACTCTAGATCATGCA
ATCAAAAGAAATGCACCTATCTATGCGGAAGTAGCAGGATTTGGCATGACAGGTGATGCTTATCATATGACTGCTCCTTG
TCCAGATTCCACTGGAGCCATTGCTTGTATGGAAGAAGCCATTCAGGATGCTGGTATTTCAAAAACTGAAATTCAGTATA
TAAATGCTCACGGCACTTCCACCGAGTATAATGACAGATTAGAAACTTTAGCCATCAAAGAAGTTTTCCAAGAACATGCC
GAAAATTTACTGGTAAGTTCAACCAAATCCATGACAGGCCACTTATTGGGGGCAGCAGGAGGGGTTGAAAGTGTAGCTAC
ATTACTTTCAATGACAAATAATTATGTTCATCCGACTATAAATTTAGAAACTCATGACCCTAAATGTGACCTGGATTACG
TACCCAATGAGGGACGCCATGCGGAACTAGATACTACTTTAGTGAATAATTTTGGCTTTGGTGGGACAAATGCTAGCTTA
ATTTTTAAAAGCTTGAAGGATTAA

Upstream 100 bases:

>100_bases
TCTAAATTATAGATTTTAGGTAAACAAGCAATAAGTTGTTTTAGCAAGCTATCAAACCTATCTTTACTGAAAGTGGGTGA
TTAATTTGAACAGGGTTGTT

Downstream 100 bases:

>100_bases
CTATTTAAGTGAGGGATGTAAAATGGGTAAGGAATGCCGCGATATTGTTGAACTAAAAGAAAAGTTAGGTATTTATGTGG
ATGATAAGTTACTACTACAA

Product: 3-oxoacyl-(acyl-carrier-protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTGLGVISPNGLGKEQFWNALQNGSSGVDEITSFDTEEFSTKIAGEVLDFEATDFFSKKEARRMDRFVQFASAASQMAVD
DAALEITDELKNSVGVSIGSGIGGLQTLEESHKKLMEKGPKRVSPLFIPMMIANMASGKVSIDLGAKGPNLTLVTACATA
AHAIGESLRILQRGECDVMITGGSEATVTPLAIAGFGSMKALSTRNDDPQKASRPFDKNRDGFVMGEGAGVLVLETLDHA
IKRNAPIYAEVAGFGMTGDAYHMTAPCPDSTGAIACMEEAIQDAGISKTEIQYINAHGTSTEYNDRLETLAIKEVFQEHA
ENLLVSSTKSMTGHLLGAAGGVESVATLLSMTNNYVHPTINLETHDPKCDLDYVPNEGRHAELDTTLVNNFGFGGTNASL
IFKSLKD

Sequences:

>Translated_407_residues
MTGLGVISPNGLGKEQFWNALQNGSSGVDEITSFDTEEFSTKIAGEVLDFEATDFFSKKEARRMDRFVQFASAASQMAVD
DAALEITDELKNSVGVSIGSGIGGLQTLEESHKKLMEKGPKRVSPLFIPMMIANMASGKVSIDLGAKGPNLTLVTACATA
AHAIGESLRILQRGECDVMITGGSEATVTPLAIAGFGSMKALSTRNDDPQKASRPFDKNRDGFVMGEGAGVLVLETLDHA
IKRNAPIYAEVAGFGMTGDAYHMTAPCPDSTGAIACMEEAIQDAGISKTEIQYINAHGTSTEYNDRLETLAIKEVFQEHA
ENLLVSSTKSMTGHLLGAAGGVESVATLLSMTNNYVHPTINLETHDPKCDLDYVPNEGRHAELDTTLVNNFGFGGTNASL
IFKSLKD
>Mature_406_residues
TGLGVISPNGLGKEQFWNALQNGSSGVDEITSFDTEEFSTKIAGEVLDFEATDFFSKKEARRMDRFVQFASAASQMAVDD
AALEITDELKNSVGVSIGSGIGGLQTLEESHKKLMEKGPKRVSPLFIPMMIANMASGKVSIDLGAKGPNLTLVTACATAA
HAIGESLRILQRGECDVMITGGSEATVTPLAIAGFGSMKALSTRNDDPQKASRPFDKNRDGFVMGEGAGVLVLETLDHAI
KRNAPIYAEVAGFGMTGDAYHMTAPCPDSTGAIACMEEAIQDAGISKTEIQYINAHGTSTEYNDRLETLAIKEVFQEHAE
NLLVSSTKSMTGHLLGAAGGVESVATLLSMTNNYVHPTINLETHDPKCDLDYVPNEGRHAELDTTLVNNFGFGGTNASLI
FKSLKD

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=415, Percent_Identity=43.6144578313253, Blast_Score=348, Evalue=4e-96,
Organism=Homo sapiens, GI223972627, Length=179, Percent_Identity=45.2513966480447, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI41872631, Length=417, Percent_Identity=26.1390887290168, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI1787337, Length=406, Percent_Identity=52.7093596059113, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1788663, Length=411, Percent_Identity=36.4963503649635, Blast_Score=234, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=38.1067961165049, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71983535, Length=256, Percent_Identity=42.578125, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI212642053, Length=366, Percent_Identity=27.0491803278689, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=279, Percent_Identity=29.0322580645161, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320904, Length=439, Percent_Identity=34.624145785877, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6325025, Length=183, Percent_Identity=27.8688524590164, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644341, Length=415, Percent_Identity=40.2409638554217, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI221330659, Length=372, Percent_Identity=27.6881720430108, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI19920632, Length=372, Percent_Identity=27.6881720430108, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24581345, Length=373, Percent_Identity=24.3967828418231, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43295; Mature: 43164

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLGVISPNGLGKEQFWNALQNGSSGVDEITSFDTEEFSTKIAGEVLDFEATDFFSKKE
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHH
ARRMDRFVQFASAASQMAVDDAALEITDELKNSVGVSIGSGIGGLQTLEESHKKLMEKGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHCCC
KRVSPLFIPMMIANMASGKVSIDLGAKGPNLTLVTACATAAHAIGESLRILQRGECDVMI
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEE
TGGSEATVTPLAIAGFGSMKALSTRNDDPQKASRPFDKNRDGFVMGEGAGVLVLETLDHA
ECCCCCEECEEEEECCCCHHECCCCCCCHHHHCCCCCCCCCCEEEECCCCEEEEHHHHHH
IKRNAPIYAEVAGFGMTGDAYHMTAPCPDSTGAIACMEEAIQDAGISKTEIQYINAHGTS
HHCCCCEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCC
TEYNDRLETLAIKEVFQEHAENLLVSSTKSMTGHLLGAAGGVESVATLLSMTNNYVHPTI
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHCCEECCEE
NLETHDPKCDLDYVPNEGRHAELDTTLVNNFGFGGTNASLIFKSLKD
EEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TGLGVISPNGLGKEQFWNALQNGSSGVDEITSFDTEEFSTKIAGEVLDFEATDFFSKKE
CCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHH
ARRMDRFVQFASAASQMAVDDAALEITDELKNSVGVSIGSGIGGLQTLEESHKKLMEKGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHCCC
KRVSPLFIPMMIANMASGKVSIDLGAKGPNLTLVTACATAAHAIGESLRILQRGECDVMI
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEE
TGGSEATVTPLAIAGFGSMKALSTRNDDPQKASRPFDKNRDGFVMGEGAGVLVLETLDHA
ECCCCCEECEEEEECCCCHHECCCCCCCHHHHCCCCCCCCCCEEEECCCCEEEEHHHHHH
IKRNAPIYAEVAGFGMTGDAYHMTAPCPDSTGAIACMEEAIQDAGISKTEIQYINAHGTS
HHCCCCEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCC
TEYNDRLETLAIKEVFQEHAENLLVSSTKSMTGHLLGAAGGVESVATLLSMTNNYVHPTI
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHCCEECCEE
NLETHDPKCDLDYVPNEGRHAELDTTLVNNFGFGGTNASLIFKSLKD
EEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]