Click here to switch to the map view.

The map label for this gene is rsmB [H]

Identifier: 188585963

GI number: 188585963

Start: 1410370

End: 1411758

Strand: Direct

Name: rsmB [H]

Synonym: Nther_1337

Alternate gene names: 188585963

Gene position: 1410370-1411758 (Clockwise)

Preceding gene: 188585962

Following gene: 188585964

Centisome position: 44.55

GC content: 35.64

Gene sequence:

>1389_bases
ATGAAGATTAAATCTTCTAGAGAACTGGCCTTTGTTGCGTATACGAGAATAATTCAGGACCAGGCCTATAGCAATCTTGT
GTTAAATCAACTTTTAGGAAAAACTGATCTTTTGGCTCAAGACAAGGCCTTGGCTTCTAGAATTACTTATGGGACTTTAC
AGTGGCAGGGTTTAATAGATTATTATCTTAAAACCCTGTCACATCGTCCTTTAAGTAAATTATCAAACAAGGCCTTATTT
TTATTAAGAATGGGTGCCTATCAAATACTGTTTTTAGATAGAGTACCACCAAGTGCTTCTGTTAATGAAACTGTCAAGGT
TGCTCATAGAAGAACACACAAAGGGATTGCCAATTTTGTCAATGGAATTCTAAGAAACTTAATTAGAAAGAAAGATCAAA
TATTATTACCGTCAAGGGATCAAGATTTACTGAACTATTTATCTGTAAAGTATTCACACCCTTATTGGATGGTAAAGTTA
TGGTACGATAAGTATGGGCTTGATAAAACTATTTCAATCATGGACCAAAATAATTCTACACCAGAAGAAGCTATTCGGGT
CAATAAACTTTTGACTAGTCTTGAAAACTTAAAAAATGAATTAGAAATGACTGGGATTCAGAGTAGACTTTCTTCAAAGA
TTGATGATGCTTTACTTGTAGATAATTTGGGTGATTTGAATAATAATACATTATTTAATTGTGGTTATTTTCAAGTCCAG
GATATAAACTCCATGGTAGTTTCGCATCTTTGTGACCCACAACAAGGTGATAATATTATTGATCTTTGTAGTGCTCCAGG
TAGTAAAACCACTCATTTAGTACAGTTGATTGACGGTCAGGGGTCGATATTGGCAGTAGATATCCATGAACATCGGCTGA
AGTTGGTTAAAGAAGCATGCCGACGATTACAAGTCAATAATGTTAATGTCAAACAGGCTGATGGTACTAAATTAATTTCT
AGGGATCAACAAGAAAACAATAAACAGCTCAAGGGACAATTTGACCTGTGCCTAATAGATGCTCCATGCTCAGGTTTAGG
GACCTTGAGAAAACGCCCCGAACTTAAATGGACAATTAGCGAACAGGACCTTAATAGTCTATCAACTCTACAAGGTAAGC
TATTAAAAGCAGGTAGTCAGCTGGTCAAACCGGGTGGAACTTTAGTCTACAGTACTTGTACTATTAACCCACAAGAAAAT
GAAGACCAAATCAATGATTTCCTAAAAAATCATCCTGATTTTGTAATGGAATCTCCACGAGCTATCTTAAAGGAAGACAC
TTTACAGGGAGGTATGATTTTATCTAACAATTCTTTACAGTACTTTCCTGAATTAAACTTAGGGGATGGCTTCTACGGGG
CCAGAATGAAAAAAACTCAGTGTGAATAA

Upstream 100 bases:

>100_bases
ACAAGTTTTAAATGCTGCGGCGATGACATATGTTGCTGCTACTGCTATGGCACTAGCTCAATTACTCCGTTTAATAATGT
TACGAGGAAGGCGTTAATTT

Downstream 100 bases:

>100_bases
TAGATAAAGGGTAGTAATCTAATTCCATTACAACTCCCTGCACTGTTAGTTGCTATGTGTCCTTTACTCTGATATACTTT
GGCATGAATAAGTAATGAAG

Product: sun protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MKIKSSRELAFVAYTRIIQDQAYSNLVLNQLLGKTDLLAQDKALASRITYGTLQWQGLIDYYLKTLSHRPLSKLSNKALF
LLRMGAYQILFLDRVPPSASVNETVKVAHRRTHKGIANFVNGILRNLIRKKDQILLPSRDQDLLNYLSVKYSHPYWMVKL
WYDKYGLDKTISIMDQNNSTPEEAIRVNKLLTSLENLKNELEMTGIQSRLSSKIDDALLVDNLGDLNNNTLFNCGYFQVQ
DINSMVVSHLCDPQQGDNIIDLCSAPGSKTTHLVQLIDGQGSILAVDIHEHRLKLVKEACRRLQVNNVNVKQADGTKLIS
RDQQENNKQLKGQFDLCLIDAPCSGLGTLRKRPELKWTISEQDLNSLSTLQGKLLKAGSQLVKPGGTLVYSTCTINPQEN
EDQINDFLKNHPDFVMESPRAILKEDTLQGGMILSNNSLQYFPELNLGDGFYGARMKKTQCE

Sequences:

>Translated_462_residues
MKIKSSRELAFVAYTRIIQDQAYSNLVLNQLLGKTDLLAQDKALASRITYGTLQWQGLIDYYLKTLSHRPLSKLSNKALF
LLRMGAYQILFLDRVPPSASVNETVKVAHRRTHKGIANFVNGILRNLIRKKDQILLPSRDQDLLNYLSVKYSHPYWMVKL
WYDKYGLDKTISIMDQNNSTPEEAIRVNKLLTSLENLKNELEMTGIQSRLSSKIDDALLVDNLGDLNNNTLFNCGYFQVQ
DINSMVVSHLCDPQQGDNIIDLCSAPGSKTTHLVQLIDGQGSILAVDIHEHRLKLVKEACRRLQVNNVNVKQADGTKLIS
RDQQENNKQLKGQFDLCLIDAPCSGLGTLRKRPELKWTISEQDLNSLSTLQGKLLKAGSQLVKPGGTLVYSTCTINPQEN
EDQINDFLKNHPDFVMESPRAILKEDTLQGGMILSNNSLQYFPELNLGDGFYGARMKKTQCE
>Mature_462_residues
MKIKSSRELAFVAYTRIIQDQAYSNLVLNQLLGKTDLLAQDKALASRITYGTLQWQGLIDYYLKTLSHRPLSKLSNKALF
LLRMGAYQILFLDRVPPSASVNETVKVAHRRTHKGIANFVNGILRNLIRKKDQILLPSRDQDLLNYLSVKYSHPYWMVKL
WYDKYGLDKTISIMDQNNSTPEEAIRVNKLLTSLENLKNELEMTGIQSRLSSKIDDALLVDNLGDLNNNTLFNCGYFQVQ
DINSMVVSHLCDPQQGDNIIDLCSAPGSKTTHLVQLIDGQGSILAVDIHEHRLKLVKEACRRLQVNNVNVKQADGTKLIS
RDQQENNKQLKGQFDLCLIDAPCSGLGTLRKRPELKWTISEQDLNSLSTLQGKLLKAGSQLVKPGGTLVYSTCTINPQEN
EDQINDFLKNHPDFVMESPRAILKEDTLQGGMILSNNSLQYFPELNLGDGFYGARMKKTQCE

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=181, Percent_Identity=40.8839779005525, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI76150625, Length=382, Percent_Identity=28.5340314136126, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI76150623, Length=382, Percent_Identity=28.5340314136126, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI8922322, Length=298, Percent_Identity=28.1879194630872, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI270288816, Length=298, Percent_Identity=28.1879194630872, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI23199998, Length=298, Percent_Identity=28.1879194630872, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI270288818, Length=298, Percent_Identity=28.1879194630872, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI39995082, Length=186, Percent_Identity=31.7204301075269, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI301336155, Length=186, Percent_Identity=31.7204301075269, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI11545785, Length=163, Percent_Identity=31.2883435582822, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI2367212, Length=458, Percent_Identity=31.2227074235808, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI87081985, Length=231, Percent_Identity=31.6017316017316, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17536757, Length=239, Percent_Identity=30.5439330543933, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25143471, Length=184, Percent_Identity=34.2391304347826, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71998419, Length=232, Percent_Identity=27.5862068965517, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI115534021, Length=232, Percent_Identity=27.5862068965517, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324268, Length=329, Percent_Identity=26.4437689969605, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319447, Length=203, Percent_Identity=31.0344827586207, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI22024126, Length=240, Percent_Identity=32.5, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24668781, Length=211, Percent_Identity=32.7014218009479, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21356513, Length=210, Percent_Identity=31.9047619047619, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21355201, Length=189, Percent_Identity=32.2751322751323, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 52170; Mature: 52170

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKSSRELAFVAYTRIIQDQAYSNLVLNQLLGKTDLLAQDKALASRITYGTLQWQGLID
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECEEEHHHHHH
YYLKTLSHRPLSKLSNKALFLLRMGAYQILFLDRVPPSASVNETVKVAHRRTHKGIANFV
HHHHHHCCCCHHHHCCCEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
NGILRNLIRKKDQILLPSRDQDLLNYLSVKYSHPYWMVKLWYDKYGLDKTISIMDQNNST
HHHHHHHHHCCCCEECCCCCHHHHHHHHHEECCCEEEEEEEECCCCCCCEEEEEECCCCC
PEEAIRVNKLLTSLENLKNELEMTGIQSRLSSKIDDALLVDNLGDLNNNTLFNCGYFQVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCEEEH
DINSMVVSHLCDPQQGDNIIDLCSAPGSKTTHLVQLIDGQGSILAVDIHEHRLKLVKEAC
HHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHH
RRLQVNNVNVKQADGTKLISRDQQENNKQLKGQFDLCLIDAPCSGLGTLRKRPELKWTIS
HHCCCCCCEEECCCCCHHHHCCHHHCCHHCCCCCCEEEEECCCCCCHHHHCCCCCEEEEC
EQDLNSLSTLQGKLLKAGSQLVKPGGTLVYSTCTINPQENEDQINDFLKNHPDFVMESPR
HHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCHHHCCCH
AILKEDTLQGGMILSNNSLQYFPELNLGDGFYGARMKKTQCE
HHHHHHCCCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIKSSRELAFVAYTRIIQDQAYSNLVLNQLLGKTDLLAQDKALASRITYGTLQWQGLID
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECEEEHHHHHH
YYLKTLSHRPLSKLSNKALFLLRMGAYQILFLDRVPPSASVNETVKVAHRRTHKGIANFV
HHHHHHCCCCHHHHCCCEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
NGILRNLIRKKDQILLPSRDQDLLNYLSVKYSHPYWMVKLWYDKYGLDKTISIMDQNNST
HHHHHHHHHCCCCEECCCCCHHHHHHHHHEECCCEEEEEEEECCCCCCCEEEEEECCCCC
PEEAIRVNKLLTSLENLKNELEMTGIQSRLSSKIDDALLVDNLGDLNNNTLFNCGYFQVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCEEEH
DINSMVVSHLCDPQQGDNIIDLCSAPGSKTTHLVQLIDGQGSILAVDIHEHRLKLVKEAC
HHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHH
RRLQVNNVNVKQADGTKLISRDQQENNKQLKGQFDLCLIDAPCSGLGTLRKRPELKWTIS
HHCCCCCCEEECCCCCHHHHCCHHHCCHHCCCCCCEEEEECCCCCCHHHHCCCCCEEEEC
EQDLNSLSTLQGKLLKAGSQLVKPGGTLVYSTCTINPQENEDQINDFLKNHPDFVMESPR
HHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCHHHCCCH
AILKEDTLQGGMILSNNSLQYFPELNLGDGFYGARMKKTQCE
HHHHHHCCCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]