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The map label for this gene is aroC [H]

Identifier: 188585906

GI number: 188585906

Start: 1348907

End: 1350133

Strand: Direct

Name: aroC [H]

Synonym: Nther_1280

Alternate gene names: 188585906

Gene position: 1348907-1350133 (Clockwise)

Preceding gene: 188585905

Following gene: 188585907

Centisome position: 42.61

GC content: 38.71

Gene sequence:

>1227_bases
ATGAGTCTTAATTTTCTAACAGCAGGTGAATCCCATGGACCAGCATTGGTAGGGATATTAGAAGGATTCTGGTCAAACTT
TGAAATTGATGAAAGCAAAATAAATTCAGAACTAGCAAGGCGTCAATCAGGTTATGGTAGGGGAGGTCGCATGAAAATCG
AAGGCGATACTGTAAATTTTCTGGGAGGTGTTCGTCAGGGTGTCACTACAGGGGCACCCATAGCTTTTCAAATATTTAAC
AAAGATTATCAGAATTGGAAAGATGAAATGAATCCGTCAAAAATAGACTCTGAAGAGTCTAGTACAAAACAATCTGAGTC
TCAGTCAAAATTTAATACCCAAGTTACAAAACCTAGACCTGGTCACGCTGATTTAGCTGGTGCGTTAAAATATGACCAAA
GTGATATTAGAAACATCTTGGAAAGATCTAGTGCCAGGGAAACAGCTATGAGAACGGCAGTGGGGTCCTTGTGTAAACAA
CTTCTTCAAGACTTAAATATCAAGATTATTAGTCATGTCACTAGAATAGGTAGTATAAGCCTATCTCAAGAGCTAACAGG
GGTAACTCATACTAATAATTTCTCTAACATGAAAGAATTAATTTCAAATCTCGAAAGATCACAACTGAATTGTATAGACC
CTAAAACAGAGCAGAAGATGATTGAAGAGATAGATTCAACACGTCTCCAAGGAGATACTCTAGGTGGTGAATTTGAAGTT
ATAGTTGAAAACCTTCCTCCGGGATTGGGAAGCCATGTTCATTATCATCGTAAACTTGATGGTCTGCTAGCAGGAGCATT
AATGGGCTTGCAGGGAATAAAAGGAGTAGAGATAGGTGCTGGGTTTCAAACGGCAACACTCCCTGGTTCTCAAATTCATG
ATGAAATTTTTTATTCCCAGGATAGAGGTTACTATCGAGATCAAAACAATGCCGGTGGTGTAGAGGGTGGTATTTCCAAT
GGTGAACCTGTGATCGTCAGAGGAGCCATGAAGCCCATACCTACACTATCCAAGCCTTTAAAAAGTGTGGATATTCATAC
TAAAGAAGCTTTTGATGCCCAAATTGAACGTTCTGATTGTTGTGCTGTCCCTTCGGCAGCTATAGTGGCTGAACATATTA
TAGCCTATGAACTTGCCAAAGTAGTGAAAGAAAAATTTGGTAGTGATTCAATAGATGAATTGAGACGAAATTATCAAGCT
TACTTTGAGTATTTAGATACTAGATAA

Upstream 100 bases:

>100_bases
GCTCAAGTAGTAAGTGTGATTTTAATTATTGTTGGAGGATATTATTTAATTCGTAATCGTAAAGAAAAAAATCAGGCAGT
ATATTTGAAGAGGTGAGGAC

Downstream 100 bases:

>100_bases
TATAGGGGGATTTTTTTGAAAAATAAATTTGACACTTTAACAGTTGAAACAGGGGTTAAATCCAAAAAAAAGTATCCTAT
CTATATTGGTAAAGCCATTC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSLNFLTAGESHGPALVGILEGFWSNFEIDESKINSELARRQSGYGRGGRMKIEGDTVNFLGGVRQGVTTGAPIAFQIFN
KDYQNWKDEMNPSKIDSEESSTKQSESQSKFNTQVTKPRPGHADLAGALKYDQSDIRNILERSSARETAMRTAVGSLCKQ
LLQDLNIKIISHVTRIGSISLSQELTGVTHTNNFSNMKELISNLERSQLNCIDPKTEQKMIEEIDSTRLQGDTLGGEFEV
IVENLPPGLGSHVHYHRKLDGLLAGALMGLQGIKGVEIGAGFQTATLPGSQIHDEIFYSQDRGYYRDQNNAGGVEGGISN
GEPVIVRGAMKPIPTLSKPLKSVDIHTKEAFDAQIERSDCCAVPSAAIVAEHIIAYELAKVVKEKFGSDSIDELRRNYQA
YFEYLDTR

Sequences:

>Translated_408_residues
MSLNFLTAGESHGPALVGILEGFWSNFEIDESKINSELARRQSGYGRGGRMKIEGDTVNFLGGVRQGVTTGAPIAFQIFN
KDYQNWKDEMNPSKIDSEESSTKQSESQSKFNTQVTKPRPGHADLAGALKYDQSDIRNILERSSARETAMRTAVGSLCKQ
LLQDLNIKIISHVTRIGSISLSQELTGVTHTNNFSNMKELISNLERSQLNCIDPKTEQKMIEEIDSTRLQGDTLGGEFEV
IVENLPPGLGSHVHYHRKLDGLLAGALMGLQGIKGVEIGAGFQTATLPGSQIHDEIFYSQDRGYYRDQNNAGGVEGGISN
GEPVIVRGAMKPIPTLSKPLKSVDIHTKEAFDAQIERSDCCAVPSAAIVAEHIIAYELAKVVKEKFGSDSIDELRRNYQA
YFEYLDTR
>Mature_407_residues
SLNFLTAGESHGPALVGILEGFWSNFEIDESKINSELARRQSGYGRGGRMKIEGDTVNFLGGVRQGVTTGAPIAFQIFNK
DYQNWKDEMNPSKIDSEESSTKQSESQSKFNTQVTKPRPGHADLAGALKYDQSDIRNILERSSARETAMRTAVGSLCKQL
LQDLNIKIISHVTRIGSISLSQELTGVTHTNNFSNMKELISNLERSQLNCIDPKTEQKMIEEIDSTRLQGDTLGGEFEVI
VENLPPGLGSHVHYHRKLDGLLAGALMGLQGIKGVEIGAGFQTATLPGSQIHDEIFYSQDRGYYRDQNNAGGVEGGISNG
EPVIVRGAMKPIPTLSKPLKSVDIHTKEAFDAQIERSDCCAVPSAAIVAEHIIAYELAKVVKEKFGSDSIDELRRNYQAY
FEYLDTR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=373, Percent_Identity=33.7801608579088, Blast_Score=142, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6321290, Length=382, Percent_Identity=30.8900523560209, Blast_Score=159, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 44886; Mature: 44755

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00788 CHORISMATE_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNFLTAGESHGPALVGILEGFWSNFEIDESKINSELARRQSGYGRGGRMKIEGDTVNF
CCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHH
LGGVRQGVTTGAPIAFQIFNKDYQNWKDEMNPSKIDSEESSTKQSESQSKFNTQVTKPRP
HHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GHADLAGALKYDQSDIRNILERSSARETAMRTAVGSLCKQLLQDLNIKIISHVTRIGSIS
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCH
LSQELTGVTHTNNFSNMKELISNLERSQLNCIDPKTEQKMIEEIDSTRLQGDTLGGEFEV
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEE
IVENLPPGLGSHVHYHRKLDGLLAGALMGLQGIKGVEIGAGFQTATLPGSQIHDEIFYSQ
HEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHCC
DRGYYRDQNNAGGVEGGISNGEPVIVRGAMKPIPTLSKPLKSVDIHTKEAFDAQIERSDC
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHH
CAVPSAAIVAEHIIAYELAKVVKEKFGSDSIDELRRNYQAYFEYLDTR
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLNFLTAGESHGPALVGILEGFWSNFEIDESKINSELARRQSGYGRGGRMKIEGDTVNF
CCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHH
LGGVRQGVTTGAPIAFQIFNKDYQNWKDEMNPSKIDSEESSTKQSESQSKFNTQVTKPRP
HHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GHADLAGALKYDQSDIRNILERSSARETAMRTAVGSLCKQLLQDLNIKIISHVTRIGSIS
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCH
LSQELTGVTHTNNFSNMKELISNLERSQLNCIDPKTEQKMIEEIDSTRLQGDTLGGEFEV
HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEE
IVENLPPGLGSHVHYHRKLDGLLAGALMGLQGIKGVEIGAGFQTATLPGSQIHDEIFYSQ
HEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHCC
DRGYYRDQNNAGGVEGGISNGEPVIVRGAMKPIPTLSKPLKSVDIHTKEAFDAQIERSDC
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHH
CAVPSAAIVAEHIIAYELAKVVKEKFGSDSIDELRRNYQAYFEYLDTR
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA