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The map label for this gene is iscR [H]

Identifier: 188585903

GI number: 188585903

Start: 1347141

End: 1347575

Strand: Direct

Name: iscR [H]

Synonym: Nther_1277

Alternate gene names: 188585903

Gene position: 1347141-1347575 (Clockwise)

Preceding gene: 188585902

Following gene: 188585904

Centisome position: 42.56

GC content: 33.56

Gene sequence:

>435_bases
GTGAAAGTATCTACTAGGAGCAAATGGGCTCTGGCATGTAGTCTCTATTATGCTGTTAATTATTCCAAGGAAGTTATTCC
ATTAAAAACGGTTTCCAAAGCCCTAGGTATTTCAGAAAAATACTTGGAACAATTGTCCATTCCATTAAAAAAGGCCGATA
TATTAGCAAGTACTAGAGGAACTCAAGGTGGATATAAATTAAAATATCACCCAGAAAAAATCACCGTATATCAAGTGTTG
AGTTCTATAGAACCAATTCATTTTGGTGAAGATGCTTCTGATCAAGCGGGCGAAAAGGAATTGTTATCAGTAACCAGTGA
ATTTTGGGATGAACTTTCTCAAGATTTAATAAAACAACTCAATCAGATCACTTTAGATGATCTCAGGAATAAATATTATC
AAAAATCGTCTCAGGGTTTAATGTATTATATTTAG

Upstream 100 bases:

>100_bases
AATAATGCTAGAAATAGGGTGATTAATAAATTTAGTGTAGAACAAGTTATCCCACAATATGAGCAATTATATCAAAAAAC
ATTAGGGAGGGTGTAAGACC

Downstream 100 bases:

>100_bases
ATCTTATGATATAAATCAAGTATTCTTTAATCGGATCAAGTATCCTATAATACTATAGTCGGGGGGAGTTAATGTTTAAA
AAGATGCTTTATGAAACTAA

Product: CarD family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MKVSTRSKWALACSLYYAVNYSKEVIPLKTVSKALGISEKYLEQLSIPLKKADILASTRGTQGGYKLKYHPEKITVYQVL
SSIEPIHFGEDASDQAGEKELLSVTSEFWDELSQDLIKQLNQITLDDLRNKYYQKSSQGLMYYI

Sequences:

>Translated_144_residues
MKVSTRSKWALACSLYYAVNYSKEVIPLKTVSKALGISEKYLEQLSIPLKKADILASTRGTQGGYKLKYHPEKITVYQVL
SSIEPIHFGEDASDQAGEKELLSVTSEFWDELSQDLIKQLNQITLDDLRNKYYQKSSQGLMYYI
>Mature_144_residues
MKVSTRSKWALACSLYYAVNYSKEVIPLKTVSKALGISEKYLEQLSIPLKKADILASTRGTQGGYKLKYHPEKITVYQVL
SSIEPIHFGEDASDQAGEKELLSVTSEFWDELSQDLIKQLNQITLDDLRNKYYQKSSQGLMYYI

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=132, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16423; Mature: 16423

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSTRSKWALACSLYYAVNYSKEVIPLKTVSKALGISEKYLEQLSIPLKKADILASTRG
CCCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHCCC
TQGGYKLKYHPEKITVYQVLSSIEPIHFGEDASDQAGEKELLSVTSEFWDELSQDLIKQL
CCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NQITLDDLRNKYYQKSSQGLMYYI
HHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MKVSTRSKWALACSLYYAVNYSKEVIPLKTVSKALGISEKYLEQLSIPLKKADILASTRG
CCCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHCCC
TQGGYKLKYHPEKITVYQVLSSIEPIHFGEDASDQAGEKELLSVTSEFWDELSQDLIKQL
CCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NQITLDDLRNKYYQKSSQGLMYYI
HHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA