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The map label for this gene is gpmB [H]

Identifier: 188585634

GI number: 188585634

Start: 1072940

End: 1073554

Strand: Direct

Name: gpmB [H]

Synonym: Nther_1007

Alternate gene names: 188585634

Gene position: 1072940-1073554 (Clockwise)

Preceding gene: 188585630

Following gene: 188585635

Centisome position: 33.89

GC content: 35.61

Gene sequence:

>615_bases
GTGACTAAGTTATACCTTACCAGACATGGTGAAACCGAATGGAATTTGCAGAAGAAAATGCAGGGATGGCACAATTCACC
ATTAACACAATTAGGTGAGAAACAAGCCAAATGGCTTGGTGACAGGCTTGCAGAAGTGGAGTTGGAAACTATATACACGA
GTACTAGTGGTAGAACACAAAGAACTGCCGAACTTATTCGAGGTAACAGAAATATTGACTTGATTCCAAAGGATAATTTG
AGAGAAATCAACCTGGGAGATTGGGAAGGTGAATTTGTCGAAAATATAAAGAAACAGGAAAATGAGGCCTTTAGAAAATT
TTGGGAAGAACCACATAATTATCGAAAAGAAACTGGGGAAACTTTTTATCAATTAAAAGATCGAGTAGTCCCCTTAATAA
AACAGATAATTTCAGATCACAATCCTAATAGCAATATTTTAGTAGTGACTCATGCTGCAGTTTTAAAAGTTTTGATGGCT
CACTTTGAAAATAGACCTATAGAAAAACTGTGGGATCCTCCTTTCATGTATCAAACTTGTTTAAATTTAGTAGAAATAAA
TGAAAATGGGTACAAGGTCCTTTTACACGGTGATACATCTCATTATCAGGAATGA

Upstream 100 bases:

>100_bases
ATTTCATAACTTGTATCTAAATACATTATCTGTATTTTAATAATTGAGAAGGCAATGTAGACTAGATATTATTAAATATT
ATTTAATTAGGAGTGATAAT

Downstream 100 bases:

>100_bases
GAGTATATTTAATAATATATAGGAATGATGTCTGATATGTTCCCCTTGAGGTAGACAGATTATGAAGATTATGGAAAGAT
CCTGTTTAACCTTAAGGGGA

Product: Phosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTKLYLTRHGETEWNLQKKMQGWHNSPLTQLGEKQAKWLGDRLAEVELETIYTSTSGRTQRTAELIRGNRNIDLIPKDNL
REINLGDWEGEFVENIKKQENEAFRKFWEEPHNYRKETGETFYQLKDRVVPLIKQIISDHNPNSNILVVTHAAVLKVLMA
HFENRPIEKLWDPPFMYQTCLNLVEINENGYKVLLHGDTSHYQE

Sequences:

>Translated_204_residues
MTKLYLTRHGETEWNLQKKMQGWHNSPLTQLGEKQAKWLGDRLAEVELETIYTSTSGRTQRTAELIRGNRNIDLIPKDNL
REINLGDWEGEFVENIKKQENEAFRKFWEEPHNYRKETGETFYQLKDRVVPLIKQIISDHNPNSNILVVTHAAVLKVLMA
HFENRPIEKLWDPPFMYQTCLNLVEINENGYKVLLHGDTSHYQE
>Mature_203_residues
TKLYLTRHGETEWNLQKKMQGWHNSPLTQLGEKQAKWLGDRLAEVELETIYTSTSGRTQRTAELIRGNRNIDLIPKDNLR
EINLGDWEGEFVENIKKQENEAFRKFWEEPHNYRKETGETFYQLKDRVVPLIKQIISDHNPNSNILVVTHAAVLKVLMAH
FENRPIEKLWDPPFMYQTCLNLVEINENGYKVLLHGDTSHYQE

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI224282149, Length=172, Percent_Identity=31.9767441860465, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI4758900, Length=172, Percent_Identity=31.9767441860465, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI64762445, Length=172, Percent_Identity=31.9767441860465, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI64762406, Length=172, Percent_Identity=31.9767441860465, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI118582286, Length=172, Percent_Identity=28.4883720930233, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI4758902, Length=172, Percent_Identity=29.0697674418605, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1790856, Length=209, Percent_Identity=32.0574162679426, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1786857, Length=186, Percent_Identity=30.1075268817204, Blast_Score=85, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25145314, Length=201, Percent_Identity=28.8557213930348, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71993390, Length=168, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17510917, Length=168, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322306, Length=191, Percent_Identity=30.3664921465969, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24643264, Length=193, Percent_Identity=28.4974093264249, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24643254, Length=193, Percent_Identity=28.4974093264249, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24643260, Length=193, Percent_Identity=28.4974093264249, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24643258, Length=193, Percent_Identity=28.4974093264249, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24643256, Length=193, Percent_Identity=28.4974093264249, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24643262, Length=193, Percent_Identity=28.4974093264249, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24643252, Length=193, Percent_Identity=28.4974093264249, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17137706, Length=193, Percent_Identity=28.4974093264249, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 24074; Mature: 23942

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLYLTRHGETEWNLQKKMQGWHNSPLTQLGEKQAKWLGDRLAEVELETIYTSTSGRTQ
CCEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHH
RTAELIRGNRNIDLIPKDNLREINLGDWEGEFVENIKKQENEAFRKFWEEPHNYRKETGE
HHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
TFYQLKDRVVPLIKQIISDHNPNSNILVVTHAAVLKVLMAHFENRPIEKLWDPPFMYQTC
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHCCCCHHHHHH
LNLVEINENGYKVLLHGDTSHYQE
HHHHEECCCCCEEEEECCHHCCCC
>Mature Secondary Structure 
TKLYLTRHGETEWNLQKKMQGWHNSPLTQLGEKQAKWLGDRLAEVELETIYTSTSGRTQ
CEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHH
RTAELIRGNRNIDLIPKDNLREINLGDWEGEFVENIKKQENEAFRKFWEEPHNYRKETGE
HHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
TFYQLKDRVVPLIKQIISDHNPNSNILVVTHAAVLKVLMAHFENRPIEKLWDPPFMYQTC
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHCCCCHHHHHH
LNLVEINENGYKVLLHGDTSHYQE
HHHHEECCCCCEEEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA