Click here to switch to the map view.

The map label for this gene is hcp

Identifier: 188585604

GI number: 188585604

Start: 1040374

End: 1042041

Strand: Direct

Name: hcp

Synonym: Nther_0977

Alternate gene names: 188585604

Gene position: 1040374-1042041 (Clockwise)

Preceding gene: 188585603

Following gene: 188585605

Centisome position: 32.87

GC content: 38.25

Gene sequence:

>1668_bases
GTGAGCATGAAATGTTTTCAATGCCAAGAAACAGTAAAGAATCAGGGATGTACAGTTAAGGGTGTTTGTGGTAAGCCTGA
TAATGTGGCGAATCTTCAAGATGTATTGATTTACACTTTAAAGGGGATTTCGTTCTATGCCCATGAAGGAAGAAACTTGG
GTGTGAAAGATGAAGAAGTGGATAGGTTTGTCATGGATAATTTATTTGCTACAGTAACTAATGTAAACTTCAGTGAACAA
GATTTTATTGATAGAATCAAGCAGTCTTTTAAAATAAGAGATCAAATAAAAGAACAAGTTATGCTAAAATACCGAGAAAA
ATACGGTGAGAATTTAGATAATAAGGTGCCCTCAAATGCGACTTGGTACACAGAAGATGAGCTTAATTTCAAAACCAAAG
GTGAAGAAGTAGGAGTTCACTCATCGGATAATGAGGATATTAATTCCTTAAGAGAACTGTTAACCTATGGTATCAAAGGT
ATAGCAGCTTATGCCCATCACGCATATACTTTAAACCAAAAAGATGATGAAATATTTGCCTTTATGCACAAAGGTTTAGC
AGCAACTACAGATGATAGCTTGAGTGTAGATGATTTGGTATCTCTAGTCATGGAGTGTGGAAAGTTTGGAGTAAATACCA
TGGCACTACTAGATAAAGCCAACACAGAAGCCTACGGTCATCCTGAACCAACTCAAATAAATATTGGTGTACGCAATAAT
CCAGGAATTTTGATCAGTGGTCACGACCTGAAGGATATGCAAGAACTACTAGAACAGACAGAAGGCACTGGTGTTGATGT
ATATACGCATGGAGAAATGCTTCCGGCTAATGCGTATCCAGCCTTTAAGAAATACGATCATTTCGTAGGTAATTACGGAA
ATGCTTGGTGGCAGCAAAATGAAGAATTTGAGAAATTTAATGGTCCAATTTTGATGACTACAAACTGTCTTGTACCACCT
AAAGATTCTTACAAAGATAGAGTGTACACAACTGGTGTAGTAGGTTTTGATGGTGTAACTCATATTCCCGAGAGAGAAGC
AGGTGAAAGCAAGGACTTCTCCCAAATTATCGAGCATGCCAAAAAATGTGCTGCTCCAGAAGAATTAGAACAGGGAGAAA
TACCGGGTGGATTTGCCCACAATGCAGTATTAAGTGTAGCAGATAAAGTAGTAGAAGCAGTTAAGAACGGTGATATCAAG
AGATTTGTTGTTATGGGCGGTTGCGACGGACGCCATAAGAGTAGAGAGTACTACACAGAATTTGCCAAAGCTCTTCCCCA
GGATACAATTATACTGACTGCCGGCTGTGCCAAGTATAGATATAATAAGCTGGATTTAGGAGATATCGGAGGAATTCCAA
GAGTATTAGATGCAGGTCAGTGTAATGACTCTTATTCCTTGGTTGTTATCGCGCAAAAACTAGCTGAAGCCTTTGAGTTA
GAAGATATTAACGATCTACCAGTTTCATATAACATTGCTTGGTACGAACAGAAGGCGGTTACAGTGCTACTATCGTTACT
GTATCTAGGTGTGAAGAAAATTTATCTAGGTCCCACCCTTCCTGCCTTCGTATCTGAAAATGTATTGAATGTGCTAGTTG
ATAAGTTTGATATGAGGCCAAATTCTAATGTAGATGAAGATTTGGAAAAAATTATGGCAGGAGAATAA

Upstream 100 bases:

>100_bases
AATCTAAAAACAGTTTTATCCAAAAACCAGGAAATTAGCAATTTATTGTGGAAAGGCCAAGAATGAAAATGATAATAATT
ACTTATAAGGAGTGATTTAT

Downstream 100 bases:

>100_bases
AATAAATATGCTACAACAACCCGCCTCAAGCCTGGGGCGGGTCTTTTTTATGCCCGGTATGGGTGTTAACTAGCTAGTTC
ATGACATCTGCCAAGCTGCA

Product: hydroxylamine reductase

Products: NA

Alternate protein names: Hybrid-cluster protein; HCP

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSMKCFQCQETVKNQGCTVKGVCGKPDNVANLQDVLIYTLKGISFYAHEGRNLGVKDEEVDRFVMDNLFATVTNVNFSEQ
DFIDRIKQSFKIRDQIKEQVMLKYREKYGENLDNKVPSNATWYTEDELNFKTKGEEVGVHSSDNEDINSLRELLTYGIKG
IAAYAHHAYTLNQKDDEIFAFMHKGLAATTDDSLSVDDLVSLVMECGKFGVNTMALLDKANTEAYGHPEPTQINIGVRNN
PGILISGHDLKDMQELLEQTEGTGVDVYTHGEMLPANAYPAFKKYDHFVGNYGNAWWQQNEEFEKFNGPILMTTNCLVPP
KDSYKDRVYTTGVVGFDGVTHIPEREAGESKDFSQIIEHAKKCAAPEELEQGEIPGGFAHNAVLSVADKVVEAVKNGDIK
RFVVMGGCDGRHKSREYYTEFAKALPQDTIILTAGCAKYRYNKLDLGDIGGIPRVLDAGQCNDSYSLVVIAQKLAEAFEL
EDINDLPVSYNIAWYEQKAVTVLLSLLYLGVKKIYLGPTLPAFVSENVLNVLVDKFDMRPNSNVDEDLEKIMAGE

Sequences:

>Translated_555_residues
MSMKCFQCQETVKNQGCTVKGVCGKPDNVANLQDVLIYTLKGISFYAHEGRNLGVKDEEVDRFVMDNLFATVTNVNFSEQ
DFIDRIKQSFKIRDQIKEQVMLKYREKYGENLDNKVPSNATWYTEDELNFKTKGEEVGVHSSDNEDINSLRELLTYGIKG
IAAYAHHAYTLNQKDDEIFAFMHKGLAATTDDSLSVDDLVSLVMECGKFGVNTMALLDKANTEAYGHPEPTQINIGVRNN
PGILISGHDLKDMQELLEQTEGTGVDVYTHGEMLPANAYPAFKKYDHFVGNYGNAWWQQNEEFEKFNGPILMTTNCLVPP
KDSYKDRVYTTGVVGFDGVTHIPEREAGESKDFSQIIEHAKKCAAPEELEQGEIPGGFAHNAVLSVADKVVEAVKNGDIK
RFVVMGGCDGRHKSREYYTEFAKALPQDTIILTAGCAKYRYNKLDLGDIGGIPRVLDAGQCNDSYSLVVIAQKLAEAFEL
EDINDLPVSYNIAWYEQKAVTVLLSLLYLGVKKIYLGPTLPAFVSENVLNVLVDKFDMRPNSNVDEDLEKIMAGE
>Mature_554_residues
SMKCFQCQETVKNQGCTVKGVCGKPDNVANLQDVLIYTLKGISFYAHEGRNLGVKDEEVDRFVMDNLFATVTNVNFSEQD
FIDRIKQSFKIRDQIKEQVMLKYREKYGENLDNKVPSNATWYTEDELNFKTKGEEVGVHSSDNEDINSLRELLTYGIKGI
AAYAHHAYTLNQKDDEIFAFMHKGLAATTDDSLSVDDLVSLVMECGKFGVNTMALLDKANTEAYGHPEPTQINIGVRNNP
GILISGHDLKDMQELLEQTEGTGVDVYTHGEMLPANAYPAFKKYDHFVGNYGNAWWQQNEEFEKFNGPILMTTNCLVPPK
DSYKDRVYTTGVVGFDGVTHIPEREAGESKDFSQIIEHAKKCAAPEELEQGEIPGGFAHNAVLSVADKVVEAVKNGDIKR
FVVMGGCDGRHKSREYYTEFAKALPQDTIILTAGCAKYRYNKLDLGDIGGIPRVLDAGQCNDSYSLVVIAQKLAEAFELE
DINDLPVSYNIAWYEQKAVTVLLSLLYLGVKKIYLGPTLPAFVSENVLNVLVDKFDMRPNSNVDEDLEKIMAGE

Specific function: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O

COG id: COG1151

COG function: function code C; 6Fe-6S prismane cluster-containing protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HCP family

Homologues:

Organism=Escherichia coli, GI87081794, Length=563, Percent_Identity=40.3197158081705, Blast_Score=451, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HCP_NATTJ (B2A0K0)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001917149.1
- ProteinModelPortal:   B2A0K0
- SMR:   B2A0K0
- GeneID:   6316866
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_0977
- HOGENOM:   HBG294215
- OMA:   THIPERE
- ProtClustDB:   PRK05290
- GO:   GO:0005737
- HAMAP:   MF_00069
- InterPro:   IPR010048
- InterPro:   IPR004137
- InterPro:   IPR011254
- InterPro:   IPR016099
- InterPro:   IPR016100
- Gene3D:   G3DSA:3.40.50.2030
- Gene3D:   G3DSA:1.20.1270.20
- PIRSF:   PIRSF000076
- TIGRFAMs:   TIGR01703

Pfam domain/function: PF03063 Prismane; SSF56821 Prismane_like

EC number: NA

Molecular weight: Translated: 62019; Mature: 61887

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMKCFQCQETVKNQGCTVKGVCGKPDNVANLQDVLIYTLKGISFYAHEGRNLGVKDEEV
CCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHH
DRFVMDNLFATVTNVNFSEQDFIDRIKQSFKIRDQIKEQVMLKYREKYGENLDNKVPSNA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TWYTEDELNFKTKGEEVGVHSSDNEDINSLRELLTYGIKGIAAYAHHAYTLNQKDDEIFA
EEEECCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHH
FMHKGLAATTDDSLSVDDLVSLVMECGKFGVNTMALLDKANTEAYGHPEPTQINIGVRNN
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECC
PGILISGHDLKDMQELLEQTEGTGVDVYTHGEMLPANAYPAFKKYDHFVGNYGNAWWQQN
CCEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCC
EEFEKFNGPILMTTNCLVPPKDSYKDRVYTTGVVGFDGVTHIPEREAGESKDFSQIIEHA
CHHHHHCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
KKCAAPEELEQGEIPGGFAHNAVLSVADKVVEAVKNGDIKRFVVMGGCDGRHKSREYYTE
HHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHH
FAKALPQDTIILTAGCAKYRYNKLDLGDIGGIPRVLDAGQCNDSYSLVVIAQKLAEAFEL
HHHHCCCCEEEEEECHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCEEEHHHHHHHHHHCC
EDINDLPVSYNIAWYEQKAVTVLLSLLYLGVKKIYLGPTLPAFVSENVLNVLVDKFDMRP
CCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
NSNVDEDLEKIMAGE
CCCHHHHHHHHHCCC
>Mature Secondary Structure 
SMKCFQCQETVKNQGCTVKGVCGKPDNVANLQDVLIYTLKGISFYAHEGRNLGVKDEEV
CCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHH
DRFVMDNLFATVTNVNFSEQDFIDRIKQSFKIRDQIKEQVMLKYREKYGENLDNKVPSNA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TWYTEDELNFKTKGEEVGVHSSDNEDINSLRELLTYGIKGIAAYAHHAYTLNQKDDEIFA
EEEECCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHH
FMHKGLAATTDDSLSVDDLVSLVMECGKFGVNTMALLDKANTEAYGHPEPTQINIGVRNN
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECC
PGILISGHDLKDMQELLEQTEGTGVDVYTHGEMLPANAYPAFKKYDHFVGNYGNAWWQQN
CCEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCC
EEFEKFNGPILMTTNCLVPPKDSYKDRVYTTGVVGFDGVTHIPEREAGESKDFSQIIEHA
CHHHHHCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
KKCAAPEELEQGEIPGGFAHNAVLSVADKVVEAVKNGDIKRFVVMGGCDGRHKSREYYTE
HHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHH
FAKALPQDTIILTAGCAKYRYNKLDLGDIGGIPRVLDAGQCNDSYSLVVIAQKLAEAFEL
HHHHCCCCEEEEEECHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCEEEHHHHHHHHHHCC
EDINDLPVSYNIAWYEQKAVTVLLSLLYLGVKKIYLGPTLPAFVSENVLNVLVDKFDMRP
CCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
NSNVDEDLEKIMAGE
CCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA