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The map label for this gene is hyuA [H]

Identifier: 188585493

GI number: 188585493

Start: 911374

End: 912930

Strand: Direct

Name: hyuA [H]

Synonym: Nther_0865

Alternate gene names: 188585493

Gene position: 911374-912930 (Clockwise)

Preceding gene: 188585492

Following gene: 188585494

Centisome position: 28.79

GC content: 38.09

Gene sequence:

>1557_bases
TTGGCGTATAGGATAGGGATAGATGTTGGCGGCACCAATACAGATGCAGTTATAATTGATGAGAAGCTTAATGTACTTTC
TAAGGCCAAACATCCGACAACGGAAGATGTCACGACTGGAATTTTTAATGTTATAGAAAAAGTAGTTTCAGATAAAAATG
TGGATACAAATAAGATTGAATACGCAATGCTAGGAACAACCCACTGTACTAACGCCATTGTAGAACGTAAAAATTTAAAT
AAAGTCCTTGTTATTCGTCTTGGTAAACCCGCTACTAGTGCTGTTAAACCCTTGACTGGATGGCCTGAAGACTTGAAATC
AGTGATTGGCAATCATCAATATATTGTCCATGGTGGTCACGAGTTTGATGGTCGAAAAATTTCCGAATTAAAAGATGATG
AGATCAGGGAAGTAGCTCGAGAAGTTAAAGGGAAAGTCAGTTCTGTAGCTATTACTTCAGTGTTTTCCCCGGTAAATGGT
GAATTCGAGCAAAGGGCTAAAGAAATTTTACAAGATGAGCTGGGCGAAAATATAAATTTTTCATTATCGCATGAAATCGG
TTCTATCGGTCTTGTAGAACGTGAAAATGCTACCGTGTTGAATGCTTCAGTAGTTGATGTAGCAAAAAAGGCAACAAAAG
CATTCGAAAATGCCTTGAAAAAATTCAATATTAATGCCAAGCAATATTTTGGTCAAAACGATGGGACTTTAATGGCTATA
GAATATGCAATTAAGTACCCAATATTGACTATCGCTTGTGGACCTACCAATAGTATTCGTGGTGCATGTTTCTTGACTGA
TCAAAAGGAAGGGCTAGTCGTAGATGTTGGTGGTACCACAACAGACATAGGTATATTAAACAAAGGTTTTCCTCGACAAT
CAACAATTTCAGTGGAAATTGGAGGCGTGAGGACTAACTTTCGAATGCCAGATCTGTTATCTCTTGGTTTAGGAGGAGGA
ACTATCATTCAAGGTGATGCCGCTGAATTCAGTATTGGACCAGCAAGTGTCGGTTATCAAATTACAAATAAATCACAGGT
CTTTGGCGGAGATACTCTAACAACGACAGATATAGCTGTAGCTGGAGGAATAGCGAATGTAGGAGATTCCAATAATTTAA
ATGATCTTGATAGTGAATTAGTGTCTTCTGTTTATCAAAAAATGACTTCTATGATTGAAGTTTCTATAGATAAAATGAAA
ACAGAGTCTACAGAGTTGCCTGTCATCCTCGTAGGTGGAGGAAGTATTCTCTTTCCTGATAAATTGGCCGGTGCTAGTAA
AGTTTATAAACCAAATCATTATGAAGTAGCAAATGCAATTGGAGCTGCTATTTCACAGGTAAGCGGTGAAGTTGAACGAA
TCTATAATTTAAGTGATATGTCGAGGGAAGAAGCGGTTGAACAGGCAAAGCAAAAGGCCATTTCTGAAGCTATCAAAGCT
GGGGCGGCAGAAGAAACTGTAGAAATAGTTGATGTTGAAGATGTGCCTTTAGCATATCTTCCTGGCAATGCTACTAGGAT
TAAAGCAAAAGCTGCGGGAGATTTATTAATTGAATAA

Upstream 100 bases:

>100_bases
AAAGGATTAAGTCTTGTAGGCCCAGCTTATTTTGGATATGAAGATGTAGAATTTATACCTGTTGAAGATCGAATTAAGCA
ATTGAAAGGGGGTAATTAGT

Downstream 100 bases:

>100_bases
TCAAAATCATAATCATATTTAAATTAAGTTAGTTTAATATCCCCCTCTGGGCGGTGACAGTCAGTTAATTAGGCTTATGA
CTGTATCGACTCTATAGGGG

Product: Hydantoinase/oxoprolinase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MAYRIGIDVGGTNTDAVIIDEKLNVLSKAKHPTTEDVTTGIFNVIEKVVSDKNVDTNKIEYAMLGTTHCTNAIVERKNLN
KVLVIRLGKPATSAVKPLTGWPEDLKSVIGNHQYIVHGGHEFDGRKISELKDDEIREVAREVKGKVSSVAITSVFSPVNG
EFEQRAKEILQDELGENINFSLSHEIGSIGLVERENATVLNASVVDVAKKATKAFENALKKFNINAKQYFGQNDGTLMAI
EYAIKYPILTIACGPTNSIRGACFLTDQKEGLVVDVGGTTTDIGILNKGFPRQSTISVEIGGVRTNFRMPDLLSLGLGGG
TIIQGDAAEFSIGPASVGYQITNKSQVFGGDTLTTTDIAVAGGIANVGDSNNLNDLDSELVSSVYQKMTSMIEVSIDKMK
TESTELPVILVGGGSILFPDKLAGASKVYKPNHYEVANAIGAAISQVSGEVERIYNLSDMSREEAVEQAKQKAISEAIKA
GAAEETVEIVDVEDVPLAYLPGNATRIKAKAAGDLLIE

Sequences:

>Translated_518_residues
MAYRIGIDVGGTNTDAVIIDEKLNVLSKAKHPTTEDVTTGIFNVIEKVVSDKNVDTNKIEYAMLGTTHCTNAIVERKNLN
KVLVIRLGKPATSAVKPLTGWPEDLKSVIGNHQYIVHGGHEFDGRKISELKDDEIREVAREVKGKVSSVAITSVFSPVNG
EFEQRAKEILQDELGENINFSLSHEIGSIGLVERENATVLNASVVDVAKKATKAFENALKKFNINAKQYFGQNDGTLMAI
EYAIKYPILTIACGPTNSIRGACFLTDQKEGLVVDVGGTTTDIGILNKGFPRQSTISVEIGGVRTNFRMPDLLSLGLGGG
TIIQGDAAEFSIGPASVGYQITNKSQVFGGDTLTTTDIAVAGGIANVGDSNNLNDLDSELVSSVYQKMTSMIEVSIDKMK
TESTELPVILVGGGSILFPDKLAGASKVYKPNHYEVANAIGAAISQVSGEVERIYNLSDMSREEAVEQAKQKAISEAIKA
GAAEETVEIVDVEDVPLAYLPGNATRIKAKAAGDLLIE
>Mature_517_residues
AYRIGIDVGGTNTDAVIIDEKLNVLSKAKHPTTEDVTTGIFNVIEKVVSDKNVDTNKIEYAMLGTTHCTNAIVERKNLNK
VLVIRLGKPATSAVKPLTGWPEDLKSVIGNHQYIVHGGHEFDGRKISELKDDEIREVAREVKGKVSSVAITSVFSPVNGE
FEQRAKEILQDELGENINFSLSHEIGSIGLVERENATVLNASVVDVAKKATKAFENALKKFNINAKQYFGQNDGTLMAIE
YAIKYPILTIACGPTNSIRGACFLTDQKEGLVVDVGGTTTDIGILNKGFPRQSTISVEIGGVRTNFRMPDLLSLGLGGGT
IIQGDAAEFSIGPASVGYQITNKSQVFGGDTLTTTDIAVAGGIANVGDSNNLNDLDSELVSSVYQKMTSMIEVSIDKMKT
ESTELPVILVGGGSILFPDKLAGASKVYKPNHYEVANAIGAAISQVSGEVERIYNLSDMSREEAVEQAKQKAISEAIKAG
AAEETVEIVDVEDVPLAYLPGNATRIKAKAAGDLLIE

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 55390; Mature: 55259

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYRIGIDVGGTNTDAVIIDEKLNVLSKAKHPTTEDVTTGIFNVIEKVVSDKNVDTNKIE
CEEEEEEEECCCCCCEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEE
YAMLGTTHCTNAIVERKNLNKVLVIRLGKPATSAVKPLTGWPEDLKSVIGNHQYIVHGGH
EEEECCHHHHHHHHHHCCCCEEEEEEECCCCHHHCCCCCCCHHHHHHHHCCCEEEEECCC
EFDGRKISELKDDEIREVAREVKGKVSSVAITSVFSPVNGEFEQRAKEILQDELGENINF
CCCCCCHHHCCHHHHHHHHHHHHCCHHHEEHHHHHCCCCCHHHHHHHHHHHHHHCCCCCE
SLSHEIGSIGLVERENATVLNASVVDVAKKATKAFENALKKFNINAKQYFGQNDGTLMAI
EEECCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEE
EYAIKYPILTIACGPTNSIRGACFLTDQKEGLVVDVGGTTTDIGILNKGFPRQSTISVEI
EEEEECCEEEEEECCCCCCCEEEEEECCCCCEEEECCCCEEEHHCCCCCCCCCCEEEEEE
GGVRTNFRMPDLLSLGLGGGTIIQGDAAEFSIGPASVGYQITNKSQVFGGDTLTTTDIAV
CCEEECCCCCHHHHCCCCCCEEEECCCCCEECCCCCCCEEECCCCEECCCCCEEECHHEE
AGGIANVGDSNNLNDLDSELVSSVYQKMTSMIEVSIDKMKTESTELPVILVGGGSILFPD
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEECCH
KLAGASKVYKPNHYEVANAIGAAISQVSGEVERIYNLSDMSREEAVEQAKQKAISEAIKA
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHHHHHHHHC
GAAEETVEIVDVEDVPLAYLPGNATRIKAKAAGDLLIE
CCCCCEEEEEEECCCCEEEECCCCEEEEEECCCCEECC
>Mature Secondary Structure 
AYRIGIDVGGTNTDAVIIDEKLNVLSKAKHPTTEDVTTGIFNVIEKVVSDKNVDTNKIE
EEEEEEEECCCCCCEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEE
YAMLGTTHCTNAIVERKNLNKVLVIRLGKPATSAVKPLTGWPEDLKSVIGNHQYIVHGGH
EEEECCHHHHHHHHHHCCCCEEEEEEECCCCHHHCCCCCCCHHHHHHHHCCCEEEEECCC
EFDGRKISELKDDEIREVAREVKGKVSSVAITSVFSPVNGEFEQRAKEILQDELGENINF
CCCCCCHHHCCHHHHHHHHHHHHCCHHHEEHHHHHCCCCCHHHHHHHHHHHHHHCCCCCE
SLSHEIGSIGLVERENATVLNASVVDVAKKATKAFENALKKFNINAKQYFGQNDGTLMAI
EEECCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEE
EYAIKYPILTIACGPTNSIRGACFLTDQKEGLVVDVGGTTTDIGILNKGFPRQSTISVEI
EEEEECCEEEEEECCCCCCCEEEEEECCCCCEEEECCCCEEEHHCCCCCCCCCCEEEEEE
GGVRTNFRMPDLLSLGLGGGTIIQGDAAEFSIGPASVGYQITNKSQVFGGDTLTTTDIAV
CCEEECCCCCHHHHCCCCCCEEEECCCCCEECCCCCCCEEECCCCEECCCCCEEECHHEE
AGGIANVGDSNNLNDLDSELVSSVYQKMTSMIEVSIDKMKTESTELPVILVGGGSILFPD
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEECCH
KLAGASKVYKPNHYEVANAIGAAISQVSGEVERIYNLSDMSREEAVEQAKQKAISEAIKA
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHHHHHHHHC
GAAEETVEIVDVEDVPLAYLPGNATRIKAKAAGDLLIE
CCCCCEEEEEEECCCCEEEECCCCEEEEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]