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The map label for this gene is htpG

Identifier: 188585484

GI number: 188585484

Start: 900396

End: 902279

Strand: Direct

Name: htpG

Synonym: Nther_0856

Alternate gene names: 188585484

Gene position: 900396-902279 (Clockwise)

Preceding gene: 188585481

Following gene: 188585485

Centisome position: 28.44

GC content: 35.14

Gene sequence:

>1884_bases
ATGGCTACTCAAGAGTTTCAAGCAGAAACGAAAAGGCTTTTAGACATTGTGATTAACTCGATTTATTCTAATAAGGAAAT
CTTTCTACGAGAATTGATTTCCAATGCAAGTGATGCCATTGATAAATTATATTACAAATCCCTAACTGATAATTCCTTGG
ATTTTAATAAAGATGATTACTATATTAAAATCACTGTGGACAAGGAAAACAGACAGCTCAAAATTTCAGATACGGGGATT
GGCATGACAAGGCAAGAATTAGAGGATAATATAGGGGTTATTGCTAGAAGTGGATCTCTCGATTTTAAAAAGGCTAATGA
ACAAGAGATTAAGGATGGACATGACATAATAGGCCAATTTGGCGTGGGCTTTTACTCTGCATTTATGGTGGCAGAAGAAG
TTACCATTATCAGTAAAGCTTATGGCAGTGATCACGCCTATAAATGGGAGTCAGAGGGGATTGAAGGATATAGTGTTAGC
CCTACTGAAAAAGAATCTGTAGGTACAGATGTGATTCTCAAGATTAAAGAAAATACTGATGATGAAGATTACGATCAGTA
TCTAGATGAACATAGATTGAAATCAATTGTTAAGAAATACTCTGATTTTATCAGATATCCAATTAAAATGGATTTGACCA
AGTCTAAACCCAAAGATGACAATGAAGAGGAATACGAAGAATATATTGAAGAAGAAACAGTAAATACCATGGTTCCCATT
TGGGAAAGAAACAAAAATGAATTAACGGATGAGGATTACAAGAACTTTTATCGAGAAAGACATTACGGCTTTGATGAACC
TATTACTCATATACACATCAATGCAGAAGGTACTATTAGTTTCAAAGCGGTATTATTTATTCCTGAAAGACCACCCTTTA
ATTTTTACACTAAAGAATTTGAAAAAGGTTTGGAATTGTACTCAAACGGAGTACTTATTATGAATAAATGTCCAGATCTG
TTACCTGATTACTTTAGTTTCGTCAGGGGTGTAGTTGATTCCGAAGATCTATCACTGAATATTTCCAGGGAAATGTTACA
GCAGGACAAACAGCTTAAATTGATTGCCAAAAATATTAAGAACAAAGTTAAAAAAGAACTTAAAAATGTTATGGAAAATG
ATAGGGAAAAATACGAGGAATTCTTTGAGTCTTTCGGTACACTACTGAAATACGGAATTTACAGTGAATTTGGGCAGAAC
AAAGAAACCCTACAGGATTTGTTGTTGTTTTATTCTTCCAAGGAAAACAAAATGGTATCTCTGGATGAGTACATTTCTAG
AATGGGAGAAGATCAAAAGTATATTTACTACGCTACTGGTGAATCAGTAGAGCGGATTGATAAGTTGCCTCAGACCGAAT
TTGTCAAGGACAAAGGTTATGAGGTGCTATACTTAACAGAAGATGTGGATGAGTTCGCTATTAAGATGATGGGCTCTTAT
CAGGATGTAGAATTCAAGTCGGTTTCCAGTAAAGATTTAGGTCTTGATTCCGAAGACGAAGAAACTTCCGATGAAAAAGA
GAAGGAATACAAGGGAATGTTTGATAAAATGGCTGAGATTTTGTCTGATAAAGTGAATACAGTAAGAGCTTCCGAGCGGC
TAAAGGATCATCCAGTATGCCTTGCAAATGAGGGTGAAATTTCAATAGAGATGGAAAAAGTATTGCAAAGCATGCCAAAT
AATCAAAACGTCCAGGCAGAAAAGGCCTTGGAAATCAATGTAAATCATGATGTTTTTGACAAGTTAACAGAGGCCTATGA
ACAAGATGAGGATAAATTTAAACTTTATACAGACTTGTTGTACAATCAGGCCTGTTTAATCGAAGGACTGCCAATTGAGG
ACCCAGTGAAATACACAAACAATGTCTGTAAGATCATGAGTTAG

Upstream 100 bases:

>100_bases
TATAGAAATTTGGGTTCACATGAATCCAAAAATTTGGTATATAAAATAGGGAGATGTTCTAACAGAAAACAGATCAAAGA
TATTAAAGGAGGGAATCGTT

Downstream 100 bases:

>100_bases
CGAAGCAATAACTAAGCTAATTATAGGAACTGTAGGTTCGGGATTAGTCCCGAACCTATAATTTTTCATTATTTTATAAA
TGTTATAGAGTAGATATTAT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MATQEFQAETKRLLDIVINSIYSNKEIFLRELISNASDAIDKLYYKSLTDNSLDFNKDDYYIKITVDKENRQLKISDTGI
GMTRQELEDNIGVIARSGSLDFKKANEQEIKDGHDIIGQFGVGFYSAFMVAEEVTIISKAYGSDHAYKWESEGIEGYSVS
PTEKESVGTDVILKIKENTDDEDYDQYLDEHRLKSIVKKYSDFIRYPIKMDLTKSKPKDDNEEEYEEYIEEETVNTMVPI
WERNKNELTDEDYKNFYRERHYGFDEPITHIHINAEGTISFKAVLFIPERPPFNFYTKEFEKGLELYSNGVLIMNKCPDL
LPDYFSFVRGVVDSEDLSLNISREMLQQDKQLKLIAKNIKNKVKKELKNVMENDREKYEEFFESFGTLLKYGIYSEFGQN
KETLQDLLLFYSSKENKMVSLDEYISRMGEDQKYIYYATGESVERIDKLPQTEFVKDKGYEVLYLTEDVDEFAIKMMGSY
QDVEFKSVSSKDLGLDSEDEETSDEKEKEYKGMFDKMAEILSDKVNTVRASERLKDHPVCLANEGEISIEMEKVLQSMPN
NQNVQAEKALEINVNHDVFDKLTEAYEQDEDKFKLYTDLLYNQACLIEGLPIEDPVKYTNNVCKIMS

Sequences:

>Translated_627_residues
MATQEFQAETKRLLDIVINSIYSNKEIFLRELISNASDAIDKLYYKSLTDNSLDFNKDDYYIKITVDKENRQLKISDTGI
GMTRQELEDNIGVIARSGSLDFKKANEQEIKDGHDIIGQFGVGFYSAFMVAEEVTIISKAYGSDHAYKWESEGIEGYSVS
PTEKESVGTDVILKIKENTDDEDYDQYLDEHRLKSIVKKYSDFIRYPIKMDLTKSKPKDDNEEEYEEYIEEETVNTMVPI
WERNKNELTDEDYKNFYRERHYGFDEPITHIHINAEGTISFKAVLFIPERPPFNFYTKEFEKGLELYSNGVLIMNKCPDL
LPDYFSFVRGVVDSEDLSLNISREMLQQDKQLKLIAKNIKNKVKKELKNVMENDREKYEEFFESFGTLLKYGIYSEFGQN
KETLQDLLLFYSSKENKMVSLDEYISRMGEDQKYIYYATGESVERIDKLPQTEFVKDKGYEVLYLTEDVDEFAIKMMGSY
QDVEFKSVSSKDLGLDSEDEETSDEKEKEYKGMFDKMAEILSDKVNTVRASERLKDHPVCLANEGEISIEMEKVLQSMPN
NQNVQAEKALEINVNHDVFDKLTEAYEQDEDKFKLYTDLLYNQACLIEGLPIEDPVKYTNNVCKIMS
>Mature_626_residues
ATQEFQAETKRLLDIVINSIYSNKEIFLRELISNASDAIDKLYYKSLTDNSLDFNKDDYYIKITVDKENRQLKISDTGIG
MTRQELEDNIGVIARSGSLDFKKANEQEIKDGHDIIGQFGVGFYSAFMVAEEVTIISKAYGSDHAYKWESEGIEGYSVSP
TEKESVGTDVILKIKENTDDEDYDQYLDEHRLKSIVKKYSDFIRYPIKMDLTKSKPKDDNEEEYEEYIEEETVNTMVPIW
ERNKNELTDEDYKNFYRERHYGFDEPITHIHINAEGTISFKAVLFIPERPPFNFYTKEFEKGLELYSNGVLIMNKCPDLL
PDYFSFVRGVVDSEDLSLNISREMLQQDKQLKLIAKNIKNKVKKELKNVMENDREKYEEFFESFGTLLKYGIYSEFGQNK
ETLQDLLLFYSSKENKMVSLDEYISRMGEDQKYIYYATGESVERIDKLPQTEFVKDKGYEVLYLTEDVDEFAIKMMGSYQ
DVEFKSVSSKDLGLDSEDEETSDEKEKEYKGMFDKMAEILSDKVNTVRASERLKDHPVCLANEGEISIEMEKVLQSMPNN
QNVQAEKALEINVNHDVFDKLTEAYEQDEDKFKLYTDLLYNQACLIEGLPIEDPVKYTNNVCKIMS

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=684, Percent_Identity=38.7426900584795, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI153792590, Length=687, Percent_Identity=37.7001455604076, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI4507677, Length=678, Percent_Identity=34.9557522123894, Blast_Score=356, Evalue=4e-98,
Organism=Homo sapiens, GI155722983, Length=633, Percent_Identity=32.5434439178515, Blast_Score=323, Evalue=3e-88,
Organism=Homo sapiens, GI154146191, Length=411, Percent_Identity=36.0097323600973, Blast_Score=242, Evalue=6e-64,
Organism=Escherichia coli, GI1786679, Length=638, Percent_Identity=36.833855799373, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17559162, Length=669, Percent_Identity=38.2660687593423, Blast_Score=403, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17542208, Length=673, Percent_Identity=36.4041604754829, Blast_Score=358, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI115535205, Length=656, Percent_Identity=32.3170731707317, Blast_Score=311, Evalue=6e-85,
Organism=Caenorhabditis elegans, GI115535167, Length=474, Percent_Identity=35.6540084388186, Blast_Score=262, Evalue=5e-70,
Organism=Saccharomyces cerevisiae, GI6325016, Length=680, Percent_Identity=36.3235294117647, Blast_Score=395, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6323840, Length=676, Percent_Identity=35.9467455621302, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI17647529, Length=686, Percent_Identity=36.734693877551, Blast_Score=403, Evalue=1e-112,
Organism=Drosophila melanogaster, GI21357739, Length=678, Percent_Identity=34.8082595870207, Blast_Score=357, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24586016, Length=645, Percent_Identity=34.1085271317829, Blast_Score=322, Evalue=4e-88,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_NATTJ (B2A875)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001917029.1
- ProteinModelPortal:   B2A875
- GeneID:   6316604
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_0856
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 73057; Mature: 72925

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQEFQAETKRLLDIVINSIYSNKEIFLRELISNASDAIDKLYYKSLTDNSLDFNKDDY
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
YIKITVDKENRQLKISDTGIGMTRQELEDNIGVIARSGSLDFKKANEQEIKDGHDIIGQF
EEEEEEECCCCEEEEECCCCCCCHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
GVGFYSAFMVAEEVTIISKAYGSDHAYKWESEGIEGYSVSPTEKESVGTDVILKIKENTD
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHCCCEEEEEEECCCC
DEDYDQYLDEHRLKSIVKKYSDFIRYPIKMDLTKSKPKDDNEEEYEEYIEEETVNTMVPI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCH
WERNKNELTDEDYKNFYRERHYGFDEPITHIHINAEGTISFKAVLFIPERPPFNFYTKEF
HCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCHHHHHH
EKGLELYSNGVLIMNKCPDLLPDYFSFVRGVVDSEDLSLNISREMLQQDKQLKLIAKNIK
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHHHCCHHHHHHHHHHH
NKVKKELKNVMENDREKYEEFFESFGTLLKYGIYSEFGQNKETLQDLLLFYSSKENKMVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEE
LDEYISRMGEDQKYIYYATGESVERIDKLPQTEFVKDKGYEVLYLTEDVDEFAIKMMGSY
HHHHHHHCCCCCEEEEEECCCHHHHHHCCCCHHHHHCCCCEEEEEECCHHHHHHHHHCCC
QDVEFKSVSSKDLGLDSEDEETSDEKEKEYKGMFDKMAEILSDKVNTVRASERLKDHPVC
CCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LANEGEISIEMEKVLQSMPNNQNVQAEKALEINVNHDVFDKLTEAYEQDEDKFKLYTDLL
EECCCCEEEEHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHH
YNQACLIEGLPIEDPVKYTNNVCKIMS
HCCHHHCCCCCCCCCHHHHCCHHHHCC
>Mature Secondary Structure 
ATQEFQAETKRLLDIVINSIYSNKEIFLRELISNASDAIDKLYYKSLTDNSLDFNKDDY
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
YIKITVDKENRQLKISDTGIGMTRQELEDNIGVIARSGSLDFKKANEQEIKDGHDIIGQF
EEEEEEECCCCEEEEECCCCCCCHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
GVGFYSAFMVAEEVTIISKAYGSDHAYKWESEGIEGYSVSPTEKESVGTDVILKIKENTD
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHCCCEEEEEEECCCC
DEDYDQYLDEHRLKSIVKKYSDFIRYPIKMDLTKSKPKDDNEEEYEEYIEEETVNTMVPI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCH
WERNKNELTDEDYKNFYRERHYGFDEPITHIHINAEGTISFKAVLFIPERPPFNFYTKEF
HCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCHHHHHH
EKGLELYSNGVLIMNKCPDLLPDYFSFVRGVVDSEDLSLNISREMLQQDKQLKLIAKNIK
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHHHCCHHHHHHHHHHH
NKVKKELKNVMENDREKYEEFFESFGTLLKYGIYSEFGQNKETLQDLLLFYSSKENKMVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEE
LDEYISRMGEDQKYIYYATGESVERIDKLPQTEFVKDKGYEVLYLTEDVDEFAIKMMGSY
HHHHHHHCCCCCEEEEEECCCHHHHHHCCCCHHHHHCCCCEEEEEECCHHHHHHHHHCCC
QDVEFKSVSSKDLGLDSEDEETSDEKEKEYKGMFDKMAEILSDKVNTVRASERLKDHPVC
CCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LANEGEISIEMEKVLQSMPNNQNVQAEKALEINVNHDVFDKLTEAYEQDEDKFKLYTDLL
EECCCCEEEEHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHH
YNQACLIEGLPIEDPVKYTNNVCKIMS
HCCHHHCCCCCCCCCHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA