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The map label for this gene is ymfD [H]

Identifier: 188585322

GI number: 188585322

Start: 711263

End: 712498

Strand: Direct

Name: ymfD [H]

Synonym: Nther_0686

Alternate gene names: 188585322

Gene position: 711263-712498 (Clockwise)

Preceding gene: 188585321

Following gene: 188585323

Centisome position: 22.47

GC content: 37.3

Gene sequence:

>1236_bases
ATGCGCACTCTTCAAGGGAATATACCAGGTTATATGATTGTCATGATTCTTTCTATGGGAGCCTTTGGTGTCATGGGAGG
CGCTTTAGTAGCCCCCGCTCTTCCAACCATTGGTAGAGCTTTTGAGGTACCAGAAGGACAGCAAGGCTTTATACTAAGTG
TTTATACTTTAGCAGCAGCCTTAAGTCTACCTTTCATTGGATATTTAATAGATGTAATTGGTAGACGAAGAGTGGCTTTG
GCTTGTTTGCTAATTGATGGAGCTGCCGGAGTTTCTATTATATTTGCCCCTAGTTTTGGGGTAGTGTTAATTTTAAGATT
TATCCAGGGGATTGGTATAGCTGGATTAATTCCAGTTGCCATGACTATTATTGGAGATTTGTTCTCAGGAGAAAAAAGAC
TACAAATTATGGGTTATTTAACAGGGATAATTTCCCTCGGAGCAGCAGTTATACCTACACTGGGTGGAGCTTTGGCGTCC
TTTGATTGGCGCTTTGTGTTTGCCGTTTATGGTCTCGGATTTGTGTTTGCCTTGTTTTTCTTGTTTACTTTGCCTGAAAC
CTCTCCGTTTCACTTTAATGCAGGTTCTAGTAGTGATAATAACAATAATCAAGGTGATAAGACTAATCAAAATACTGCTC
ACAAATCTCCTATAGAATATATTAATTCATTATTTACAGTTTTCAAAAATAAAAGTATTCGTAATATTATGTTTCAACCG
TTAATGAACTACTTTTTTTTATATGCTTTGGTAACCTTTTTCCCGATATTTTTAGTGACAGTCCACGGTTTCGCAGAAAT
ATTTAATGGACTAGCCCTGTCAATGCAAGGACTGTTTTCAGCCATAATTGCTTCTCGAGCGGATTTAGCAGCTCGTTTTA
TGACCTGGTGGCAAAGAATTTCGATAGGATTTATTTTGAAAGGTATTGCCTTTTTATTAATGCCTTTATGGCCTACAGGG
AGTTTTTTACTTAGCATAAGTATTATCATATATGGAGTAGGGTTTGGGATTGTTTCGCCTACTATATACAACAGGGCCAC
CAAGTTACCACCTCAAGACCTGATTGGCTCGGTAGTTGCAATTTTTAATACCATGAGATTTTTAGGAATGACTTTGTCTC
CATTTTTATTGGGAATCATTCTTGGCTTTACTACATTAAATGTGGTATTTTTAATTGTTGGTGTAGTTTCAATCATGTGG
GGGACTTTTTCCATGTCACAAAAAATGATTGCTTAA

Upstream 100 bases:

>100_bases
CAGGCGTGATGAATTACTTTCTGAATTAGAAGGCCTAAAAACAAGTCCTGTTATACATAAGTAATGTTATCAGTAATTGT
CAGAAAATAGAGGTGATTGA

Downstream 100 bases:

>100_bases
TATACTAAAACTGAAACTTCTTGATAGCTGACTTTGCCTGCCTTAATGGCAGGCTTTTTTTATGAAATTGATTTTTACAT
TTATCAACATTCTACTTTAA

Product: major facilitator superfamily MFS_1

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MRTLQGNIPGYMIVMILSMGAFGVMGGALVAPALPTIGRAFEVPEGQQGFILSVYTLAAALSLPFIGYLIDVIGRRRVAL
ACLLIDGAAGVSIIFAPSFGVVLILRFIQGIGIAGLIPVAMTIIGDLFSGEKRLQIMGYLTGIISLGAAVIPTLGGALAS
FDWRFVFAVYGLGFVFALFFLFTLPETSPFHFNAGSSSDNNNNQGDKTNQNTAHKSPIEYINSLFTVFKNKSIRNIMFQP
LMNYFFLYALVTFFPIFLVTVHGFAEIFNGLALSMQGLFSAIIASRADLAARFMTWWQRISIGFILKGIAFLLMPLWPTG
SFLLSISIIIYGVGFGIVSPTIYNRATKLPPQDLIGSVVAIFNTMRFLGMTLSPFLLGIILGFTTLNVVFLIVGVVSIMW
GTFSMSQKMIA

Sequences:

>Translated_411_residues
MRTLQGNIPGYMIVMILSMGAFGVMGGALVAPALPTIGRAFEVPEGQQGFILSVYTLAAALSLPFIGYLIDVIGRRRVAL
ACLLIDGAAGVSIIFAPSFGVVLILRFIQGIGIAGLIPVAMTIIGDLFSGEKRLQIMGYLTGIISLGAAVIPTLGGALAS
FDWRFVFAVYGLGFVFALFFLFTLPETSPFHFNAGSSSDNNNNQGDKTNQNTAHKSPIEYINSLFTVFKNKSIRNIMFQP
LMNYFFLYALVTFFPIFLVTVHGFAEIFNGLALSMQGLFSAIIASRADLAARFMTWWQRISIGFILKGIAFLLMPLWPTG
SFLLSISIIIYGVGFGIVSPTIYNRATKLPPQDLIGSVVAIFNTMRFLGMTLSPFLLGIILGFTTLNVVFLIVGVVSIMW
GTFSMSQKMIA
>Mature_411_residues
MRTLQGNIPGYMIVMILSMGAFGVMGGALVAPALPTIGRAFEVPEGQQGFILSVYTLAAALSLPFIGYLIDVIGRRRVAL
ACLLIDGAAGVSIIFAPSFGVVLILRFIQGIGIAGLIPVAMTIIGDLFSGEKRLQIMGYLTGIISLGAAVIPTLGGALAS
FDWRFVFAVYGLGFVFALFFLFTLPETSPFHFNAGSSSDNNNNQGDKTNQNTAHKSPIEYINSLFTVFKNKSIRNIMFQP
LMNYFFLYALVTFFPIFLVTVHGFAEIFNGLALSMQGLFSAIIASRADLAARFMTWWQRISIGFILKGIAFLLMPLWPTG
SFLLSISIIIYGVGFGIVSPTIYNRATKLPPQDLIGSVVAIFNTMRFLGMTLSPFLLGIILGFTTLNVVFLIVGVVSIMW
GTFSMSQKMIA

Specific function: Involved in secretion of bacillibactin [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324264, Length=180, Percent_Identity=35.5555555555556, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322070, Length=202, Percent_Identity=30.1980198019802, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322071, Length=179, Percent_Identity=27.3743016759777, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44572; Mature: 44572

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]