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The map label for this gene is minD [H]

Identifier: 188585159

GI number: 188585159

Start: 543199

End: 543996

Strand: Direct

Name: minD [H]

Synonym: Nther_0520

Alternate gene names: 188585159

Gene position: 543199-543996 (Clockwise)

Preceding gene: 188585158

Following gene: 188585160

Centisome position: 17.16

GC content: 36.97

Gene sequence:

>798_bases
ATGGGAGAGGTTATTGTTGTTACCAGTGGTAAGGGTGGTGTCGGTAAAACTACAACTGTGGCCAATGTAGGCACTGGTTT
AGCTTTAAAAAACAAAAGTGTAGCTTTATTGGATGCCGATATAGGTTTACGTAACTTGGATGTAATTTTGGGTTTAGAAA
ATCGGATAGTATATGATATGGTTGATGTAACACAGGGACAAGCCAAACTAAATCAAGCCTTAATTAAAGATAAGCGTTTC
CCTGATCTCTATTTGCTTCCTGCACCTCAAACTAAGGATAAAACAGCTATTAATCCAGATGAAATGAGAAATTTATGTGG
CGAATTGAAGAGTAAGTTTGATTACGTAATAGTAGACTCACCGGCCGGTATAGAACAGGGATTTCAAAATGCAATAGCAG
GTGCAGATAGGGCAATTGTAGTAACTACTCCAGAAGTTACAGCTGCAAGGGATGCAGATAGAATAATTGGTTTATTGGAA
GCTGAAGAAATTAATGACCATAAATTAATAATCAATCGAATTAGACCTGATATGGTACATAGAAATGATATGTTGGACAT
AGATGATATTATAGGTTTGTTGTCAATTGAATTGCTGGGAGTAGTACCTGACGATGAACAGGTGATTGTTTCCACTAACA
AGGGAGAACCACTAGCAAGTCAGACGGGTAAAAAGGCTAGTCGTGCATACCAAAATATAACAAGGAGGATAATGGGAGAA
AAAGTGCCTCTCATGACTTTAGATCATGACTCTGGGATTATGAATAAATTGAAAAAATTTATCGGATTAGCTAATTAG

Upstream 100 bases:

>100_bases
CCCAATATCCGGAGCGGGCATTTATTAACGGTAATCAAATAGTTGTCGAAGATATAGACCAAAAAACTCTGACTGATAAA
TTGTAAGGAGGTCTAATTGT

Downstream 100 bases:

>100_bases
GGGGTAGTGTAGAATGTTAAGAAAAAATATGAGTAAAGATATTGCTAAAGACCGGTTGCGTCTTTTACTTGTTCACGATC
GGGCCAACATGTCTCCGGAG

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MGEVIVVTSGKGGVGKTTTVANVGTGLALKNKSVALLDADIGLRNLDVILGLENRIVYDMVDVTQGQAKLNQALIKDKRF
PDLYLLPAPQTKDKTAINPDEMRNLCGELKSKFDYVIVDSPAGIEQGFQNAIAGADRAIVVTTPEVTAARDADRIIGLLE
AEEINDHKLIINRIRPDMVHRNDMLDIDDIIGLLSIELLGVVPDDEQVIVSTNKGEPLASQTGKKASRAYQNITRRIMGE
KVPLMTLDHDSGIMNKLKKFIGLAN

Sequences:

>Translated_265_residues
MGEVIVVTSGKGGVGKTTTVANVGTGLALKNKSVALLDADIGLRNLDVILGLENRIVYDMVDVTQGQAKLNQALIKDKRF
PDLYLLPAPQTKDKTAINPDEMRNLCGELKSKFDYVIVDSPAGIEQGFQNAIAGADRAIVVTTPEVTAARDADRIIGLLE
AEEINDHKLIINRIRPDMVHRNDMLDIDDIIGLLSIELLGVVPDDEQVIVSTNKGEPLASQTGKKASRAYQNITRRIMGE
KVPLMTLDHDSGIMNKLKKFIGLAN
>Mature_264_residues
GEVIVVTSGKGGVGKTTTVANVGTGLALKNKSVALLDADIGLRNLDVILGLENRIVYDMVDVTQGQAKLNQALIKDKRFP
DLYLLPAPQTKDKTAINPDEMRNLCGELKSKFDYVIVDSPAGIEQGFQNAIAGADRAIVVTTPEVTAARDADRIIGLLEA
EEINDHKLIINRIRPDMVHRNDMLDIDDIIGLLSIELLGVVPDDEQVIVSTNKGEPLASQTGKKASRAYQNITRRIMGEK
VPLMTLDHDSGIMNKLKKFIGLAN

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=268, Percent_Identity=45.8955223880597, Blast_Score=239, Evalue=1e-64,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 28793; Mature: 28662

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEVIVVTSGKGGVGKTTTVANVGTGLALKNKSVALLDADIGLRNLDVILGLENRIVYDM
CCCEEEEECCCCCCCCCEEEEECCCCEEECCCCEEEEECCCCCCEEEEEEECCCCEEEEH
VDVTQGQAKLNQALIKDKRFPDLYLLPAPQTKDKTAINPDEMRNLCGELKSKFDYVIVDS
HHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
PAGIEQGFQNAIAGADRAIVVTTPEVTAARDADRIIGLLEAEEINDHKLIINRIRPDMVH
CCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHEEHHHCCCCCCEEEEECCCHHHHC
RNDMLDIDDIIGLLSIELLGVVPDDEQVIVSTNKGEPLASQTGKKASRAYQNITRRIMGE
CCCCCCHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHCC
KVPLMTLDHDSGIMNKLKKFIGLAN
CCCEEEEECCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
GEVIVVTSGKGGVGKTTTVANVGTGLALKNKSVALLDADIGLRNLDVILGLENRIVYDM
CCEEEEECCCCCCCCCEEEEECCCCEEECCCCEEEEECCCCCCEEEEEEECCCCEEEEH
VDVTQGQAKLNQALIKDKRFPDLYLLPAPQTKDKTAINPDEMRNLCGELKSKFDYVIVDS
HHCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
PAGIEQGFQNAIAGADRAIVVTTPEVTAARDADRIIGLLEAEEINDHKLIINRIRPDMVH
CCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHEEHHHCCCCCCEEEEECCCHHHHC
RNDMLDIDDIIGLLSIELLGVVPDDEQVIVSTNKGEPLASQTGKKASRAYQNITRRIMGE
CCCCCCHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHCC
KVPLMTLDHDSGIMNKLKKFIGLAN
CCCEEEEECCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 8459776; 1400224; 9384377 [H]