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The map label for this gene is grdD [H]

Identifier: 188585115

GI number: 188585115

Start: 505183

End: 506343

Strand: Direct

Name: grdD [H]

Synonym: Nther_0476

Alternate gene names: 188585115

Gene position: 505183-506343 (Clockwise)

Preceding gene: 188585114

Following gene: 188585116

Centisome position: 15.96

GC content: 40.48

Gene sequence:

>1161_bases
TTGTCTCAAAAAGTTAAAAATCAATTATCAGAAGTTTTTCATGAACTTGCTGAAGCTTTAGAGTCCGGTCAATACGGTAA
AAAATCTAAAATTTGTGTAACAACTTTGGGAAGTGAACATGGTCCTGAAGAAGTGGTTAAAGGTGCAGAATTGGCAAAGC
AACAAAACCCAGGAATAGATATTACTCTAGTTGGGCCTAAAGTAGACACTAAACTAACATATGCTAAAGAGACAGACTGT
GAGGAAACTGTCCACAAAACTATGGAAGATTTGTTATCAAAAGGGGAAGCCGATGCATCAGTAACTATGCATTACAATTT
CCCAGTTGGAACGGCCACAGTAGGAAAGGTGATCACCCCTGGGTTAGGTAAAGAAATGTTAATAGCCACGACTACAGGTA
CAGCCGGAATGAATCGGATTGAGGCCATGATTAAAAATGCCATTTACGGTGTGATTACTGCCAAGGCCTTAGGTAACCCT
GATCCTAAAATTGGGATACTGAATGTGGATGGAGCCAAACAAGTAGAAAAGGCACTTATTGACTTAAAAGAAAATGGTTA
TTCTATTGAGTTTGCAGAATCGGCCAGACAAGATGGTGGCTTCGTCATGAGAGGAAACGATCTACTAGCAGGTTCAGCTG
ATGTAATGGTCACTGATACATTAACAGGAAACCTTCTAATGAAAATCTTCTCAGCCTATACCACAGGTGGAAGTTACGAG
TCTTTAGGTTATGGTTATGGGCCTGGAGTTGGTAAAGATCAAAAGCAAGTCGTGAACATTATCTCTAGGGCTTCTGGTGC
CCCAGTGATTGCCGGTGCTATTAAATTTGCAGCAGAAGCTAGTGCCGGTGGCATAGTTAAATTAACTAATGAAGAATTTA
AAAAAGCGGAACAGGCTGGCTTAAATGAGATACTAGAAGGATCGAAATCTAGTCAAGATGCAGGAGAAACAGAAGAAGTC
ACACCACCTCCCAAAAAACCTGTTAGTGAAGAAATCTCAGGTATGGACATCATGATTTTAGAAGATGCTCGAAAGGTTTT
ATGGAAAGAAGACGTTTATGCAGAAACGGGAATGGGCTGTGCTGGTCCCGTAGTCATGGTTGCTCCTGAAGATAAAGAAG
AAGCAGAAAAAATCCTCAGAGAACATGGTTATCTAAGTTAA

Upstream 100 bases:

>100_bases
AAGAGGAAATCAAACAAATAGTAGCTGGTTCGTTACGGGACTTAGCAGATTCTTTATCTGAAAATGCAGATAACGAGTCA
GACAGTTAGGGGGTGAAATC

Downstream 100 bases:

>100_bases
ATAAAATACCGGCCGCATTGGCGGCCGGTTGCAGTCTACAAATCTATTTACTTTATTTGAAAAAGTTCTCTTTAAATATA
ACAATTAAATACTAAGATTG

Product: Glycine reductase

Products: NA

Alternate protein names: Protein PC alpha [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSQKVKNQLSEVFHELAEALESGQYGKKSKICVTTLGSEHGPEEVVKGAELAKQQNPGIDITLVGPKVDTKLTYAKETDC
EETVHKTMEDLLSKGEADASVTMHYNFPVGTATVGKVITPGLGKEMLIATTTGTAGMNRIEAMIKNAIYGVITAKALGNP
DPKIGILNVDGAKQVEKALIDLKENGYSIEFAESARQDGGFVMRGNDLLAGSADVMVTDTLTGNLLMKIFSAYTTGGSYE
SLGYGYGPGVGKDQKQVVNIISRASGAPVIAGAIKFAAEASAGGIVKLTNEEFKKAEQAGLNEILEGSKSSQDAGETEEV
TPPPKKPVSEEISGMDIMILEDARKVLWKEDVYAETGMGCAGPVVMVAPEDKEEAEKILREHGYLS

Sequences:

>Translated_386_residues
MSQKVKNQLSEVFHELAEALESGQYGKKSKICVTTLGSEHGPEEVVKGAELAKQQNPGIDITLVGPKVDTKLTYAKETDC
EETVHKTMEDLLSKGEADASVTMHYNFPVGTATVGKVITPGLGKEMLIATTTGTAGMNRIEAMIKNAIYGVITAKALGNP
DPKIGILNVDGAKQVEKALIDLKENGYSIEFAESARQDGGFVMRGNDLLAGSADVMVTDTLTGNLLMKIFSAYTTGGSYE
SLGYGYGPGVGKDQKQVVNIISRASGAPVIAGAIKFAAEASAGGIVKLTNEEFKKAEQAGLNEILEGSKSSQDAGETEEV
TPPPKKPVSEEISGMDIMILEDARKVLWKEDVYAETGMGCAGPVVMVAPEDKEEAEKILREHGYLS
>Mature_385_residues
SQKVKNQLSEVFHELAEALESGQYGKKSKICVTTLGSEHGPEEVVKGAELAKQQNPGIDITLVGPKVDTKLTYAKETDCE
ETVHKTMEDLLSKGEADASVTMHYNFPVGTATVGKVITPGLGKEMLIATTTGTAGMNRIEAMIKNAIYGVITAKALGNPD
PKIGILNVDGAKQVEKALIDLKENGYSIEFAESARQDGGFVMRGNDLLAGSADVMVTDTLTGNLLMKIFSAYTTGGSYES
LGYGYGPGVGKDQKQVVNIISRASGAPVIAGAIKFAAEASAGGIVKLTNEEFKKAEQAGLNEILEGSKSSQDAGETEEVT
PPPKKPVSEEISGMDIMILEDARKVLWKEDVYAETGMGCAGPVVMVAPEDKEEAEKILREHGYLS

Specific function: In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a c

COG id: COG0416

COG function: function code I; Fatty acid/phospholipid biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003664
- InterPro:   IPR012116 [H]

Pfam domain/function: PF02504 FA_synthesis [H]

EC number: =1.21.4.2; =1.21.4.3; =1.21.4.4 [H]

Molecular weight: Translated: 40968; Mature: 40837

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKVKNQLSEVFHELAEALESGQYGKKSKICVTTLGSEHGPEEVVKGAELAKQQNPGID
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEE
ITLVGPKVDTKLTYAKETDCEETVHKTMEDLLSKGEADASVTMHYNFPVGTATVGKVITP
EEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHCC
GLGKEMLIATTTGTAGMNRIEAMIKNAIYGVITAKALGNPDPKIGILNVDGAKQVEKALI
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEHHHCCCCCCCEEEEECCCHHHHHHHHH
DLKENGYSIEFAESARQDGGFVMRGNDLLAGSADVMVTDTLTGNLLMKIFSAYTTGGSYE
HHHCCCCEEEEHHHHCCCCCEEEECCEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCCC
SLGYGYGPGVGKDQKQVVNIISRASGAPVIAGAIKFAAEASAGGIVKLTNEEFKKAEQAG
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
LNEILEGSKSSQDAGETEEVTPPPKKPVSEEISGMDIMILEDARKVLWKEDVYAETGMGC
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCC
AGPVVMVAPEDKEEAEKILREHGYLS
CCCEEEECCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQKVKNQLSEVFHELAEALESGQYGKKSKICVTTLGSEHGPEEVVKGAELAKQQNPGID
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEE
ITLVGPKVDTKLTYAKETDCEETVHKTMEDLLSKGEADASVTMHYNFPVGTATVGKVITP
EEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHCC
GLGKEMLIATTTGTAGMNRIEAMIKNAIYGVITAKALGNPDPKIGILNVDGAKQVEKALI
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEHHHCCCCCCCEEEEECCCHHHHHHHHH
DLKENGYSIEFAESARQDGGFVMRGNDLLAGSADVMVTDTLTGNLLMKIFSAYTTGGSYE
HHHCCCCEEEEHHHHCCCCCEEEECCEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCCC
SLGYGYGPGVGKDQKQVVNIISRASGAPVIAGAIKFAAEASAGGIVKLTNEEFKKAEQAG
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
LNEILEGSKSSQDAGETEEVTPPPKKPVSEEISGMDIMILEDARKVLWKEDVYAETGMGC
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCC
AGPVVMVAPEDKEEAEKILREHGYLS
CCCEEEECCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11737196; 1587286 [H]