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The map label for this gene is fimB [H]

Identifier: 188585021

GI number: 188585021

Start: 398284

End: 398868

Strand: Direct

Name: fimB [H]

Synonym: Nther_0382

Alternate gene names: 188585021

Gene position: 398284-398868 (Clockwise)

Preceding gene: 188585020

Following gene: 188585022

Centisome position: 12.58

GC content: 36.41

Gene sequence:

>585_bases
TTGACAGAAACTGTAAGATTCATGACCCAAAAAGAGTTAGATAAATTGTTTCGAACTATAGAGAAAAGCAAAGATAAGCA
CTGGCTACGTGATATAACCATGTTTAGGATAGCTTATCGGTGCGGGTTGAGAGCTTCTGAAGTTGGGTTGATACAGGTAT
CAGATTTTAATCCAAAGATGAATGAACTATATGTTAGACGGAACAAAAACTCTCTTAATAATACAATTAGGTTGGATAAT
AAAACTGCTCGCTACCTTAAGAAATATATCAAATCCTATCAATTGAAAGAGAACGAGATAATGTTCAAAAGCCAAAAAAG
GTCACCAATTTCACGGCAGAATTTGGACAGGATTATGAAGAAGTACTGTGAAAAAGCAAAAATAAAAGATGTTACAAATT
GGCATTTCCACGTGATGAAGCACTCCATAGCAGTTCACCTAGCTGAAACGGGTCTGGACGTGAAAGAGCTTCAGCATTAC
TTGGGACATAGGAACATAGCTAGCACCCTGGTATATTTTCAATTTACAACCAGACAGCAAGACGAAATGTATCAGAAGAT
AAGCAAGAACAATCAATTGGTGTAA

Upstream 100 bases:

>100_bases
TACAAGCTATAAATCCCGTCATAGAAGTGTAAATCCAATTTTTATAAATGGTCAAAATGGTCTTTTTGACCATATTTTAA
AGCAGAGGAGGTGAAGATTA

Downstream 100 bases:

>100_bases
AATGAGGTTTCATCTATATGTATATCAATCAAATTTAGAATAATAATACATTTTTACAATAAAATAACACTTTTTTATTG
ACAGGTATCAGATAATTGTT

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MTETVRFMTQKELDKLFRTIEKSKDKHWLRDITMFRIAYRCGLRASEVGLIQVSDFNPKMNELYVRRNKNSLNNTIRLDN
KTARYLKKYIKSYQLKENEIMFKSQKRSPISRQNLDRIMKKYCEKAKIKDVTNWHFHVMKHSIAVHLAETGLDVKELQHY
LGHRNIASTLVYFQFTTRQQDEMYQKISKNNQLV

Sequences:

>Translated_194_residues
MTETVRFMTQKELDKLFRTIEKSKDKHWLRDITMFRIAYRCGLRASEVGLIQVSDFNPKMNELYVRRNKNSLNNTIRLDN
KTARYLKKYIKSYQLKENEIMFKSQKRSPISRQNLDRIMKKYCEKAKIKDVTNWHFHVMKHSIAVHLAETGLDVKELQHY
LGHRNIASTLVYFQFTTRQQDEMYQKISKNNQLV
>Mature_193_residues
TETVRFMTQKELDKLFRTIEKSKDKHWLRDITMFRIAYRCGLRASEVGLIQVSDFNPKMNELYVRRNKNSLNNTIRLDNK
TARYLKKYIKSYQLKENEIMFKSQKRSPISRQNLDRIMKKYCEKAKIKDVTNWHFHVMKHSIAVHLAETGLDVKELQHYL
GHRNIASTLVYFQFTTRQQDEMYQKISKNNQLV

Specific function: FimB is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimB switches f

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1790767, Length=169, Percent_Identity=31.9526627218935, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790768, Length=171, Percent_Identity=29.8245614035088, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1789261, Length=165, Percent_Identity=27.8787878787879, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 23370; Mature: 23238

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETVRFMTQKELDKLFRTIEKSKDKHWLRDITMFRIAYRCGLRASEVGLIQVSDFNPKM
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCH
NELYVRRNKNSLNNTIRLDNKTARYLKKYIKSYQLKENEIMFKSQKRSPISRQNLDRIMK
HHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCHHHECCCCCCCCCHHHHHHHHH
KYCEKAKIKDVTNWHFHVMKHSIAVHLAETGLDVKELQHYLGHRNIASTLVYFQFTTRQQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHEEECCCCH
DEMYQKISKNNQLV
HHHHHHHHCCCCCC
>Mature Secondary Structure 
TETVRFMTQKELDKLFRTIEKSKDKHWLRDITMFRIAYRCGLRASEVGLIQVSDFNPKM
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCH
NELYVRRNKNSLNNTIRLDNKTARYLKKYIKSYQLKENEIMFKSQKRSPISRQNLDRIMK
HHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCHHHECCCCCCCCCHHHHHHHHH
KYCEKAKIKDVTNWHFHVMKHSIAVHLAETGLDVKELQHYLGHRNIASTLVYFQFTTRQQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHEEECCCCH
DEMYQKISKNNQLV
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]