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The map label for this gene is mod [H]

Identifier: 188585004

GI number: 188585004

Start: 379761

End: 381674

Strand: Direct

Name: mod [H]

Synonym: Nther_0364

Alternate gene names: 188585004

Gene position: 379761-381674 (Clockwise)

Preceding gene: 188585003

Following gene: 188585005

Centisome position: 12.0

GC content: 32.08

Gene sequence:

>1914_bases
ATGAAAAAATTTAACGGTGAAAGTAAAGACATAGTAGCTGAAAATATTTCTAAACTCAAGGAACTTTTTCCTGAAGTGGA
AAGTGAGGGTAAAATAGATTTTGAAAGGTTGCAAGAAATATTAGGGGAGTATATTGAAGACAAAGAAGAAAAATATAGAT
TCGAATGGAACGGTAAATCTAAAGCTATTAAATTATCACAAACGCCTTCTACTGGAACACTTAGGCCCTGCAAAGAAGAA
AGTAAAAATTGGGATGAAACTGAAAATCTGTTTATTGAAGGAGATAATCTTGAAGTATTAAAGTTGCTTCAGAAGACTTA
TCACAGTAGTATTAAGATGATTTATATAGACCCACCTTACAATACAGGTGGAGACTTTGTTTATGAAGATGATTTTCAAG
ATAACTTAAATAATTATCTTAAAATAACAGGTCAAATTAATGAAGAAGGAAAGAAAAATAGTACTAATACAGAAAATGGT
GGAAGATTTCATACTAAATGGTTGAATATGATGTATCCAAGGCTGAAATTAGCAAGAAACTTACTTAACGATCAAGGAGT
AATATTTATTTCCATTGACGATAACGAATCAGGTAACCTATGGAAAGTGTGTAATGAGATCTTTGGCGAGACAAACTTTG
TTGCTGAAATAACTGTCATAGTAAAAACAGAAGGACGTAGGTATGGTTTTTTTGCAAAATCACATGAGAAAATCTATGTT
TATGCTAAGAACATTGATAACTTAGCTCTAAATGAGATTGATATCAAAGGTAAAAAATTTACTTATAGAGATGAATTTGG
AGGCTTTAACATTAAAGAACTGAGAAATCAAAACACTAGAGCTTTTAATTCTAGTAACAGACCAAATTTAAGATATCCAT
TCTATGTTAATACTGATAATGTAGATGAGAATGGATTTATGGAAGTAAGTGTTGACTATCAAGAAGGATGGGAAGAGGTT
TATCCAATGATAACCAATGGTTTGAAAAGTGTTTGGAGATGGGGGAAGGAATCTGCTAGGCAGCAAGAAAATAAAAATTT
AGTAGCAAGAAGAGGTCGTGATGGTATAATCCGAATATATCAGAAATATCGCAAATTAACTGAAATACCCAAAACAGTAT
GGAAAGATAAGGAGATAATTTCTATTAAAGGAACAAAAGAGGTACAAGAATTATTAGGAAGTGGAATTTTTGATTTTCCC
AAGCCTGTTAAGTTATTGTCAGATATTATTACCATAGCAACTGATCAAGATTCTATTATATTAGACTTTTTTTCAGGGGC
CGCTACTACTGCTCACGCTACAATCAAAAAAAATGCTGAAGATGGTGGCACCCGAAAATATATAATGGTGCAACTACCTG
AGAAGTCAGACGAAAAATCAGAAGCATACAAGGCTGGTTATAAAAATATTTCCGAGATAGGCAAAGAACGCATACGCCGA
GCAGGAGAAAAAATCCTTGATGAAAACAAAGATAAAGAAGGTATAGAAAACTTAGATACAGGTTTTAAAGTGTTCAAATT
AGATTCATCAAACCTTAAAGAATGGAACCCTGATTATGACAACTTAGAAATGACTCTTGAAGACATGGTAGAGAACTTTG
TTGATGGAAGAACTGAAGAAGATGTGGTATATGAAATTATGCTTAAATATGGCATTGATTTAACCTTCCCTATAGAAACT
ACCGAGATTGATGGCAAAAAGGTTTATAATATCGGTTTTGGTGCTTTATTTGTTTGTTTAGATGATGAAATAACATTAAA
TGTTGTAAAGAGTATAGCTAAACTAAAAGAAGACATTGATCCAGAAATCACAAGAGTAGTATTTAAAGACAACGGTTTTC
AGAGTGATGCTGCTAAAACTAATGCAATAGAAATACTTAAACGACATGGTATAGAAGAAATAATGAGCATCTAG

Upstream 100 bases:

>100_bases
GAAAATGAATGTAGAGATAAAAAAGTTAAAAGAAGAGAAGAAAAACTTAATTGATAAGCTAAACAGCTAAATCTGACAAA
AGTATGGGAGGGTAACTGCA

Downstream 100 bases:

>100_bases
GGGGTGTTTAGATGAAATTACAATTTAATCCTAACTTAGACTTTCAACAAGAGGCTATTAGATCAATTGTAGATATATTT
GAAGGACAACCTATTACGCA

Product: DNA methylase N-4/N-6 domain protein

Products: NA

Alternate protein names: M.EcoP15I; EcoP15I methyltransferase [H]

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MKKFNGESKDIVAENISKLKELFPEVESEGKIDFERLQEILGEYIEDKEEKYRFEWNGKSKAIKLSQTPSTGTLRPCKEE
SKNWDETENLFIEGDNLEVLKLLQKTYHSSIKMIYIDPPYNTGGDFVYEDDFQDNLNNYLKITGQINEEGKKNSTNTENG
GRFHTKWLNMMYPRLKLARNLLNDQGVIFISIDDNESGNLWKVCNEIFGETNFVAEITVIVKTEGRRYGFFAKSHEKIYV
YAKNIDNLALNEIDIKGKKFTYRDEFGGFNIKELRNQNTRAFNSSNRPNLRYPFYVNTDNVDENGFMEVSVDYQEGWEEV
YPMITNGLKSVWRWGKESARQQENKNLVARRGRDGIIRIYQKYRKLTEIPKTVWKDKEIISIKGTKEVQELLGSGIFDFP
KPVKLLSDIITIATDQDSIILDFFSGAATTAHATIKKNAEDGGTRKYIMVQLPEKSDEKSEAYKAGYKNISEIGKERIRR
AGEKILDENKDKEGIENLDTGFKVFKLDSSNLKEWNPDYDNLEMTLEDMVENFVDGRTEEDVVYEIMLKYGIDLTFPIET
TEIDGKKVYNIGFGALFVCLDDEITLNVVKSIAKLKEDIDPEITRVVFKDNGFQSDAAKTNAIEILKRHGIEEIMSI

Sequences:

>Translated_637_residues
MKKFNGESKDIVAENISKLKELFPEVESEGKIDFERLQEILGEYIEDKEEKYRFEWNGKSKAIKLSQTPSTGTLRPCKEE
SKNWDETENLFIEGDNLEVLKLLQKTYHSSIKMIYIDPPYNTGGDFVYEDDFQDNLNNYLKITGQINEEGKKNSTNTENG
GRFHTKWLNMMYPRLKLARNLLNDQGVIFISIDDNESGNLWKVCNEIFGETNFVAEITVIVKTEGRRYGFFAKSHEKIYV
YAKNIDNLALNEIDIKGKKFTYRDEFGGFNIKELRNQNTRAFNSSNRPNLRYPFYVNTDNVDENGFMEVSVDYQEGWEEV
YPMITNGLKSVWRWGKESARQQENKNLVARRGRDGIIRIYQKYRKLTEIPKTVWKDKEIISIKGTKEVQELLGSGIFDFP
KPVKLLSDIITIATDQDSIILDFFSGAATTAHATIKKNAEDGGTRKYIMVQLPEKSDEKSEAYKAGYKNISEIGKERIRR
AGEKILDENKDKEGIENLDTGFKVFKLDSSNLKEWNPDYDNLEMTLEDMVENFVDGRTEEDVVYEIMLKYGIDLTFPIET
TEIDGKKVYNIGFGALFVCLDDEITLNVVKSIAKLKEDIDPEITRVVFKDNGFQSDAAKTNAIEILKRHGIEEIMSI
>Mature_637_residues
MKKFNGESKDIVAENISKLKELFPEVESEGKIDFERLQEILGEYIEDKEEKYRFEWNGKSKAIKLSQTPSTGTLRPCKEE
SKNWDETENLFIEGDNLEVLKLLQKTYHSSIKMIYIDPPYNTGGDFVYEDDFQDNLNNYLKITGQINEEGKKNSTNTENG
GRFHTKWLNMMYPRLKLARNLLNDQGVIFISIDDNESGNLWKVCNEIFGETNFVAEITVIVKTEGRRYGFFAKSHEKIYV
YAKNIDNLALNEIDIKGKKFTYRDEFGGFNIKELRNQNTRAFNSSNRPNLRYPFYVNTDNVDENGFMEVSVDYQEGWEEV
YPMITNGLKSVWRWGKESARQQENKNLVARRGRDGIIRIYQKYRKLTEIPKTVWKDKEIISIKGTKEVQELLGSGIFDFP
KPVKLLSDIITIATDQDSIILDFFSGAATTAHATIKKNAEDGGTRKYIMVQLPEKSDEKSEAYKAGYKNISEIGKERIRR
AGEKILDENKDKEGIENLDTGFKVFKLDSSNLKEWNPDYDNLEMTLEDMVENFVDGRTEEDVVYEIMLKYGIDLTFPIET
TEIDGKKVYNIGFGALFVCLDDEITLNVVKSIAKLKEDIDPEITRVVFKDNGFQSDAAKTNAIEILKRHGIEEIMSI

Specific function: Binds the system-specific DNA recognition site 5'- CAGCAC-3'. Necessary for both restriction and methylation (of one of the two A's) [H]

COG id: COG2189

COG function: function code L; Adenine specific DNA methylase Mod

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002295
- InterPro:   IPR002941
- InterPro:   IPR002052 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 73517; Mature: 73517

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFNGESKDIVAENISKLKELFPEVESEGKIDFERLQEILGEYIEDKEEKYRFEWNGKS
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHCEEEEECCCC
KAIKLSQTPSTGTLRPCKEESKNWDETENLFIEGDNLEVLKLLQKTYHSSIKMIYIDPPY
CEEEEECCCCCCCCCCCHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCC
NTGGDFVYEDDFQDNLNNYLKITGQINEEGKKNSTNTENGGRFHTKWLNMMYPRLKLARN
CCCCCEEECCCHHHCCCCEEEEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
LLNDQGVIFISIDDNESGNLWKVCNEIFGETNFVAEITVIVKTEGRRYGFFAKSHEKIYV
HCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCEECCEECCCCEEEE
YAKNIDNLALNEIDIKGKKFTYRDEFGGFNIKELRNQNTRAFNSSNRPNLRYPFYVNTDN
EEECCCCCEEEEEECCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEEECCCC
VDENGFMEVSVDYQEGWEEVYPMITNGLKSVWRWGKESARQQENKNLVARRGRDGIIRIY
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHH
QKYRKLTEIPKTVWKDKEIISIKGTKEVQELLGSGIFDFPKPVKLLSDIITIATDQDSII
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHEECCCCCEE
LDFFSGAATTAHATIKKNAEDGGTRKYIMVQLPEKSDEKSEAYKAGYKNISEIGKERIRR
EEECCCCCHHEEHEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AGEKILDENKDKEGIENLDTGFKVFKLDSSNLKEWNPDYDNLEMTLEDMVENFVDGRTEE
HHHHHHHCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
DVVYEIMLKYGIDLTFPIETTEIDGKKVYNIGFGALFVCLDDEITLNVVKSIAKLKEDID
HHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCEEEEEEECCCHHHHHHHHHHHHHHCCC
PEITRVVFKDNGFQSDAAKTNAIEILKRHGIEEIMSI
CCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MKKFNGESKDIVAENISKLKELFPEVESEGKIDFERLQEILGEYIEDKEEKYRFEWNGKS
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHCEEEEECCCC
KAIKLSQTPSTGTLRPCKEESKNWDETENLFIEGDNLEVLKLLQKTYHSSIKMIYIDPPY
CEEEEECCCCCCCCCCCHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCC
NTGGDFVYEDDFQDNLNNYLKITGQINEEGKKNSTNTENGGRFHTKWLNMMYPRLKLARN
CCCCCEEECCCHHHCCCCEEEEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
LLNDQGVIFISIDDNESGNLWKVCNEIFGETNFVAEITVIVKTEGRRYGFFAKSHEKIYV
HCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCEECCEECCCCEEEE
YAKNIDNLALNEIDIKGKKFTYRDEFGGFNIKELRNQNTRAFNSSNRPNLRYPFYVNTDN
EEECCCCCEEEEEECCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEEECCCC
VDENGFMEVSVDYQEGWEEVYPMITNGLKSVWRWGKESARQQENKNLVARRGRDGIIRIY
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHH
QKYRKLTEIPKTVWKDKEIISIKGTKEVQELLGSGIFDFPKPVKLLSDIITIATDQDSII
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHEECCCCCEE
LDFFSGAATTAHATIKKNAEDGGTRKYIMVQLPEKSDEKSEAYKAGYKNISEIGKERIRR
EEECCCCCHHEEHEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AGEKILDENKDKEGIENLDTGFKVFKLDSSNLKEWNPDYDNLEMTLEDMVENFVDGRTEE
HHHHHHHCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
DVVYEIMLKYGIDLTFPIETTEIDGKKVYNIGFGALFVCLDDEITLNVVKSIAKLKEDID
HHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCEEEEEEECCCHHHHHHHHHHHHHHCCC
PEITRVVFKDNGFQSDAAKTNAIEILKRHGIEEIMSI
CCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2837577 [H]