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The map label for this gene is dppA [H]

Identifier: 188584953

GI number: 188584953

Start: 328751

End: 329566

Strand: Direct

Name: dppA [H]

Synonym: Nther_0312

Alternate gene names: 188584953

Gene position: 328751-329566 (Clockwise)

Preceding gene: 188584952

Following gene: 188584954

Centisome position: 10.39

GC content: 40.2

Gene sequence:

>816_bases
ATGAAAGTGTATATATCTGCGGACTTGGAAGGGATAACAGGAGTAGTAGGTAGAGAACATGTAAATCCCGAGGGTTCAGA
ATATCAAAGGGCTCGCGATTTAATGACTCGAGAAGTTAATGCCGCTATCAAAGGTGCATATCAAGGAGGAGCTGAACATG
TAGTAGTAAACGATGCCCATGGCCCCATGACTAATTTGATGATTGAAAATTTAGAAACTGAGGCCGAGCTAATTACAGGT
ACTCCTAAGCCTCAAGGAATGATGGCTGGTTTAACGGAAGAATTTGATCTAGTGTTTTTAATTGGCTATCATTCTAAAAA
AGGAGATCCTGGTATACTCTCCCATTCATACAGCGGGGGGACAGTTAAACAAATTAAATTGAATGGTTTAGAGGTAGGAG
AACCGGGGATGAATAGCTATCTTGCAGGTTATTATCAAGTCCCCGTTGGTTTAGTTACAGGTGACGACAGGGTAACAACC
AATACCAAAGATTTGATTGGGGAACAATTAAAGACAGTTGCTGTTAAATCTGCCTTATCTAGGTCAGCTGCTAAGTGTAT
GACTCCCACCAAGGCCTGTAAATTAATAGAGGAACGCGCCACACAAGCAGTGTCAGAGCTGTCCAAGAAGAAATATACAA
TCTTAACAGCAGAAAAACCCCTAGAATTGTCTATGAGCTTTTTAGATCGGGGCATGGCAGAAAAGGCTGCTCAATTACCT
AATACAAAATTAGAAAACACAACTGTTATCTATCAGCATGATGATATGCTATCTATATATGAAGCTATGCAAGCTATGCT
AATGCTTGTTAGATAA

Upstream 100 bases:

>100_bases
AAAAAGGATATAGTAGGACAAGTTCGACCAGCTTTTACCCTTAATTTTGTGTAATATAATTTAATATAAATAGTTAAAAC
GAAAATTGGAGGGAAATACT

Downstream 100 bases:

>100_bases
AAGTGAAAAATAGCTATTGATATTTGGTAGCTTGATAAGGATATTTACTGGATATTTAGGTCATTAATTTTTGAAATATA
ACTTATTTCAGAGGAGGAAT

Product: peptidase M55 D-aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MKVYISADLEGITGVVGREHVNPEGSEYQRARDLMTREVNAAIKGAYQGGAEHVVVNDAHGPMTNLMIENLETEAELITG
TPKPQGMMAGLTEEFDLVFLIGYHSKKGDPGILSHSYSGGTVKQIKLNGLEVGEPGMNSYLAGYYQVPVGLVTGDDRVTT
NTKDLIGEQLKTVAVKSALSRSAAKCMTPTKACKLIEERATQAVSELSKKKYTILTAEKPLELSMSFLDRGMAEKAAQLP
NTKLENTTVIYQHDDMLSIYEAMQAMLMLVR

Sequences:

>Translated_271_residues
MKVYISADLEGITGVVGREHVNPEGSEYQRARDLMTREVNAAIKGAYQGGAEHVVVNDAHGPMTNLMIENLETEAELITG
TPKPQGMMAGLTEEFDLVFLIGYHSKKGDPGILSHSYSGGTVKQIKLNGLEVGEPGMNSYLAGYYQVPVGLVTGDDRVTT
NTKDLIGEQLKTVAVKSALSRSAAKCMTPTKACKLIEERATQAVSELSKKKYTILTAEKPLELSMSFLDRGMAEKAAQLP
NTKLENTTVIYQHDDMLSIYEAMQAMLMLVR
>Mature_271_residues
MKVYISADLEGITGVVGREHVNPEGSEYQRARDLMTREVNAAIKGAYQGGAEHVVVNDAHGPMTNLMIENLETEAELITG
TPKPQGMMAGLTEEFDLVFLIGYHSKKGDPGILSHSYSGGTVKQIKLNGLEVGEPGMNSYLAGYYQVPVGLVTGDDRVTT
NTKDLIGEQLKTVAVKSALSRSAAKCMTPTKACKLIEERATQAVSELSKKKYTILTAEKPLELSMSFLDRGMAEKAAQLP
NTKLENTTVIYQHDDMLSIYEAMQAMLMLVR

Specific function: Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear [H]

COG id: COG2362

COG function: function code E; D-aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M55 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007035 [H]

Pfam domain/function: PF04951 Peptidase_M55 [H]

EC number: NA

Molecular weight: Translated: 29533; Mature: 29533

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYISADLEGITGVVGREHVNPEGSEYQRARDLMTREVNAAIKGAYQGGAEHVVVNDAH
CEEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
GPMTNLMIENLETEAELITGTPKPQGMMAGLTEEFDLVFLIGYHSKKGDPGILSHSYSGG
CCHHHHHHHCCCCCHHEEECCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCEEECCCCC
TVKQIKLNGLEVGEPGMNSYLAGYYQVPVGLVTGDDRVTTNTKDLIGEQLKTVAVKSALS
EEEEEEECCEECCCCCCHHHHCEEEECCEEEEECCCCEECCHHHHHHHHHHHHHHHHHHH
RSAAKCMTPTKACKLIEERATQAVSELSKKKYTILTAEKPLELSMSFLDRGMAEKAAQLP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHCCHHHHHHHCC
NTKLENTTVIYQHDDMLSIYEAMQAMLMLVR
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVYISADLEGITGVVGREHVNPEGSEYQRARDLMTREVNAAIKGAYQGGAEHVVVNDAH
CEEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
GPMTNLMIENLETEAELITGTPKPQGMMAGLTEEFDLVFLIGYHSKKGDPGILSHSYSGG
CCHHHHHHHCCCCCHHEEECCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCEEECCCCC
TVKQIKLNGLEVGEPGMNSYLAGYYQVPVGLVTGDDRVTTNTKDLIGEQLKTVAVKSALS
EEEEEEECCEECCCCCCHHHHCEEEECCEEEEECCCCEECCHHHHHHHHHHHHHHHHHHH
RSAAKCMTPTKACKLIEERATQAVSELSKKKYTILTAEKPLELSMSFLDRGMAEKAAQLP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHCCHHHHHHHCC
NTKLENTTVIYQHDDMLSIYEAMQAMLMLVR
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]