Click here to switch to the map view.

The map label for this gene is rpoB [H]

Identifier: 188584828

GI number: 188584828

Start: 207673

End: 211197

Strand: Direct

Name: rpoB [H]

Synonym: Nther_0186

Alternate gene names: 188584828

Gene position: 207673-211197 (Clockwise)

Preceding gene: 188584826

Following gene: 188584829

Centisome position: 6.56

GC content: 39.55

Gene sequence:

>3525_bases
ATGGCTAAACCTGCATCTGAAAACCTAAGAAGAAGTTATTCAAAGCTTGATGAGGTCTTTGAATTACCTGATTTAATTGA
AATTCAAAAAAGTTCTTATCAATGGTTTCTGGATGAAGGACTTAAAGAAATGTTTGATGACATATCACCGATAGAAGATT
TTACCGGTGGTTTAGTTTTGGAATTTGTGGATTATTCCTTAGGAGAACCTAAATATTCTGTTGAGGATTGTAAAGAACGA
GATGTAACTTATTCAGTACCTTTAAAGGTGAAAGTAAGACTAGTGAACCAAGAGACTGGCGAGGTCAAAGAACAAGAAGT
CTTTATGGGAGACTTTCCTTTAATGACTGAAAATGGGACTTTCATCATAAATGGGGCTGAGCGAGTTATAGTCAGTCAGC
TAGTACGTTCTCCAGGAGTATATTTTAGTAGTGAAATTGATTCAAATGGAAACACACTATACTCGGGCACTATTATTCCT
AATCGAGGTGCCTGGCTAGAATTTGAAATGAATGCCCAAAATGTTATTTCCGTTAGGGTCGACCGCACTAGGAAATTACC
TGTAACAGTACTAATAAGAGCTTTAGGATATGGTACAGACGACGATATTTTCCATCTATTCGGTGAAGATCCTAGAATAA
AAGCCACACTAGAGAAGGATCATACCGATTCCTACGAGGCTGGTATTCTTGAGATCTATAAACGCTTAAGACCTGGAGAG
CCTCTAAATGTTGAAAATGCTAAGAGTCTATTTGAGTCCCTATTTTTTGACCCCAAGCGTTATGACTTAGCTAAAGTTGG
GCGCCATAAGATTAATCAAAAATTAGAGTTAGGCGATCGACTTCTTGGCAAAACAGCTCGGGAAACAATCACAGATGATG
AAACCGGTGAGGTAATTATAGAAGAAGGAACAGTTATTGACACTCAAGATTTGGAAAAACTTGAGCAATCAGGCATCACT
AGTATTCGTATTGGTAAAGATGATCAGGAAGACAGGGACTGTGTTGTCCTAACTAATGGTGATGTGGATAAAAATGTAAA
GAACCTGACAAGAAATGATATTGTAGCATCAATTGGATATATGCTAAACCTTTTAGATGGATTAGGCTTTGTTGATGATA
TTGATCACTTGGGTAATAGGCGATTGCGTTGTGTGGGGGAATTGTTACAAAATCAATTCCGAATAGGTCTTTCTAGAATG
GAAAGAGTAGTAAGAGAGAGAATGACTATTCAAGATGTGGATTCCATCACCCCCTCAGCCCTGATAAACATTAGACCTGT
AATCGCATCAATTAAAGAATTCTTTGGAAGCAGTCAGCTTTCACAATTTATGGACCAAACTAATCCTTTAGCAGAACTTA
CCCATAAACGAAGATTAAGTGCATTAGGTCCCGGTGGACTAAGCCGTGAAAGAGCCGGTTTTGAAGTTAGAGACGTACAT
CATTCACATTATGGAAGAATGTGTCCTATCGAGACTCCAGAAGGACCGAATATCGGCTTGATCAGTTCTCTGTCATCTTA
CGGAAAGGTTAATGAGTTTGGTTTTATTGAAACTCCATATAGAAAAGTAGATAAAGAAAATGGACTGGTCACAGAAAAGA
TTGAGTATTTATCTGCTCATGAAGAAGATAAATATGTAATCGCCCAGGCAAACACTCCTTTAGATAGCGATGGTTACTTT
AGTTCCGATAGAATTACTGCTCGTTATCGTCATGAAACTTTAATTACCACTCCCGACAAAATTGATTACATGGATGTGTC
TCCTCGACAGTTAGTAAGTGTTGCTACAGCACAAATACCATTTTTAGAAAACGACGATGCGAACAGGGCTTTGATGGGAA
GTAACATGCAGCGTCAAGCTGTTCCGTTGCTACAAACAGAGTCACCTTTGGTGGGTACTGGAATGGAATATAGAACAGCT
TATGACTCTGGAGCAGTTGTTAAAAGCCGAGCCGATGGTACAGTTGATAAGGTGCAATCTAACGAAATATGGGTTAGAAG
AAATGATAATGCTAAGGGCCGTGTTGTTAACGGACGAACTGGTGAGGTTTTTGAAGGCGAAACAGGAGAGGTAAGAGCAG
GTTACGATATTTATAAACTGCAGAAATTCCAACGTTCTAACCAAGGGACTTGTATGAATCAAGTACCCATTGTTGAGGAA
GGCCAACAAATCACAGAAAATCAAATACTAGCAGATGGTCCTTCTACTGACAATGGTGAAATTGCTTTAGGTCAAAATGT
CCTGGTAGGCTTCATGCCATGGGAAGGTTATAATTACGAGGACGCTATTTTGATTAGCGAAAAATTAGTAAAGGACGATA
CCTTTACTTCCATTCATATAGAAGAATACGAAGCTGAGGCAAGAGATGCTAAATTAGGTCCTGAGGAAATTACTAGAGAT
ATTCCCAATGTGGGTGAAGATGCTCTTAAGAACTTAGATGAGCGTGGAATAGTTCGGATTGGGGCTGAAGTCAAATCAGG
AGATATACTAGTAGGTAAAGTCACTCCTAAAGGTGAAACAGAACTAACAGCTGAGGAGCGTTTATTAAGAGCTATCTTTG
GTGAGAAAGCACGAGAAGTTAGAGACACATCATTGAAAGTACCTCATGGTGAACATGGTATTGTTGTTGATGTGAAAGTG
TTTAATAGAGATGATGGGGACGAGTTACCCCCAGGGGTAAATCAACTAGTTAGGGTTTATATCGCTCAAAAACGTAAAAT
TTCAGAAGGTGACAAAATGGCAGGGCGCCACGGAAATAAAGGTGTTATTGCCAAAATTTTACCTGAAGAAGATATGCCCT
TTTTACCTGATGGAACTCCTTTAGAAATTATTCTAAGTCCTCTAGGTGTTCCTTCAAGGATGAACTTAGGTCAGGTTCTA
GAAACCCACCTAGGTTGGGCTGCCAAAGCCTTAGGATTAAAAATGGCATCACCAGTTTTCGATGGAGCGGATGAAGATGA
GATCCTTGAAACTCTCAAAGAAGCAGGCCTACCTGAAAACGGTAAGACTCAATTGGTTGACGGTAGGACAGGAGAGCCCT
TTGACAATGAGGTTACTGTTGGATATATCTACATGCTGAAACTAGCTCACTTAGTTGACGACAAAATTCACGCTCGTTCA
ACAGGTCCTTATTCACTAGTTACTCAGCAGCCTCTAGGTGGTAAGGCACAGTTTGGTGGTCAGCGTTTTGGAGAAATGGA
AGTTTGGGCCCTTGAAGCTTATGGTGCTGCTTACAGTCTACAAGAATTGCTCACAGTTAAGAGTGACGATGTCGTTGGTA
GAGTTAAGACATACGAATCAATTGTCAAAGGCGACAATGTTCCTGAACCGGGAATACCTGAATCATTCAAAGTACTAATC
AAAGAGTTACAGAGTTTAGGAATGGATGTCAAAGTGCTTAATGAAGAACAAGGATTAGTATCTATTAAAGATGGTGAAGG
AAATGAAGAGGTTGTATCGGTAGAAGATTTGAATTTGGATTTAAAAGACGCAGACCAAGATAGTTCAAGTCAGCGTGATG
AATAG

Upstream 100 bases:

>100_bases
CATCAAGTTAGAATATTTTTTTTTTACTAGGGCATAATAAATTGGATAGGTGTTGGTGTAAAATTGTTAAAAATTTGGGT
GTGAGGGGTGATACGTATCT

Downstream 100 bases:

>100_bases
CACAACAAACTTAAGAAAGAATTCCCTTGAAGCTTAAGCTTAGTTTGCAACTTTTCATGAATTTGTTTACCATTATTGGT
AAAGAAGGGAGAGATGGCCC

Product: DNA-directed RNA polymerase, beta subunit

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1174; Mature: 1173

Protein sequence:

>1174_residues
MAKPASENLRRSYSKLDEVFELPDLIEIQKSSYQWFLDEGLKEMFDDISPIEDFTGGLVLEFVDYSLGEPKYSVEDCKER
DVTYSVPLKVKVRLVNQETGEVKEQEVFMGDFPLMTENGTFIINGAERVIVSQLVRSPGVYFSSEIDSNGNTLYSGTIIP
NRGAWLEFEMNAQNVISVRVDRTRKLPVTVLIRALGYGTDDDIFHLFGEDPRIKATLEKDHTDSYEAGILEIYKRLRPGE
PLNVENAKSLFESLFFDPKRYDLAKVGRHKINQKLELGDRLLGKTARETITDDETGEVIIEEGTVIDTQDLEKLEQSGIT
SIRIGKDDQEDRDCVVLTNGDVDKNVKNLTRNDIVASIGYMLNLLDGLGFVDDIDHLGNRRLRCVGELLQNQFRIGLSRM
ERVVRERMTIQDVDSITPSALINIRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRERAGFEVRDVH
HSHYGRMCPIETPEGPNIGLISSLSSYGKVNEFGFIETPYRKVDKENGLVTEKIEYLSAHEEDKYVIAQANTPLDSDGYF
SSDRITARYRHETLITTPDKIDYMDVSPRQLVSVATAQIPFLENDDANRALMGSNMQRQAVPLLQTESPLVGTGMEYRTA
YDSGAVVKSRADGTVDKVQSNEIWVRRNDNAKGRVVNGRTGEVFEGETGEVRAGYDIYKLQKFQRSNQGTCMNQVPIVEE
GQQITENQILADGPSTDNGEIALGQNVLVGFMPWEGYNYEDAILISEKLVKDDTFTSIHIEEYEAEARDAKLGPEEITRD
IPNVGEDALKNLDERGIVRIGAEVKSGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGEHGIVVDVKV
FNRDDGDELPPGVNQLVRVYIAQKRKISEGDKMAGRHGNKGVIAKILPEEDMPFLPDGTPLEIILSPLGVPSRMNLGQVL
ETHLGWAAKALGLKMASPVFDGADEDEILETLKEAGLPENGKTQLVDGRTGEPFDNEVTVGYIYMLKLAHLVDDKIHARS
TGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYSLQELLTVKSDDVVGRVKTYESIVKGDNVPEPGIPESFKVLI
KELQSLGMDVKVLNEEQGLVSIKDGEGNEEVVSVEDLNLDLKDADQDSSSQRDE

Sequences:

>Translated_1174_residues
MAKPASENLRRSYSKLDEVFELPDLIEIQKSSYQWFLDEGLKEMFDDISPIEDFTGGLVLEFVDYSLGEPKYSVEDCKER
DVTYSVPLKVKVRLVNQETGEVKEQEVFMGDFPLMTENGTFIINGAERVIVSQLVRSPGVYFSSEIDSNGNTLYSGTIIP
NRGAWLEFEMNAQNVISVRVDRTRKLPVTVLIRALGYGTDDDIFHLFGEDPRIKATLEKDHTDSYEAGILEIYKRLRPGE
PLNVENAKSLFESLFFDPKRYDLAKVGRHKINQKLELGDRLLGKTARETITDDETGEVIIEEGTVIDTQDLEKLEQSGIT
SIRIGKDDQEDRDCVVLTNGDVDKNVKNLTRNDIVASIGYMLNLLDGLGFVDDIDHLGNRRLRCVGELLQNQFRIGLSRM
ERVVRERMTIQDVDSITPSALINIRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRERAGFEVRDVH
HSHYGRMCPIETPEGPNIGLISSLSSYGKVNEFGFIETPYRKVDKENGLVTEKIEYLSAHEEDKYVIAQANTPLDSDGYF
SSDRITARYRHETLITTPDKIDYMDVSPRQLVSVATAQIPFLENDDANRALMGSNMQRQAVPLLQTESPLVGTGMEYRTA
YDSGAVVKSRADGTVDKVQSNEIWVRRNDNAKGRVVNGRTGEVFEGETGEVRAGYDIYKLQKFQRSNQGTCMNQVPIVEE
GQQITENQILADGPSTDNGEIALGQNVLVGFMPWEGYNYEDAILISEKLVKDDTFTSIHIEEYEAEARDAKLGPEEITRD
IPNVGEDALKNLDERGIVRIGAEVKSGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGEHGIVVDVKV
FNRDDGDELPPGVNQLVRVYIAQKRKISEGDKMAGRHGNKGVIAKILPEEDMPFLPDGTPLEIILSPLGVPSRMNLGQVL
ETHLGWAAKALGLKMASPVFDGADEDEILETLKEAGLPENGKTQLVDGRTGEPFDNEVTVGYIYMLKLAHLVDDKIHARS
TGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYSLQELLTVKSDDVVGRVKTYESIVKGDNVPEPGIPESFKVLI
KELQSLGMDVKVLNEEQGLVSIKDGEGNEEVVSVEDLNLDLKDADQDSSSQRDE
>Mature_1173_residues
AKPASENLRRSYSKLDEVFELPDLIEIQKSSYQWFLDEGLKEMFDDISPIEDFTGGLVLEFVDYSLGEPKYSVEDCKERD
VTYSVPLKVKVRLVNQETGEVKEQEVFMGDFPLMTENGTFIINGAERVIVSQLVRSPGVYFSSEIDSNGNTLYSGTIIPN
RGAWLEFEMNAQNVISVRVDRTRKLPVTVLIRALGYGTDDDIFHLFGEDPRIKATLEKDHTDSYEAGILEIYKRLRPGEP
LNVENAKSLFESLFFDPKRYDLAKVGRHKINQKLELGDRLLGKTARETITDDETGEVIIEEGTVIDTQDLEKLEQSGITS
IRIGKDDQEDRDCVVLTNGDVDKNVKNLTRNDIVASIGYMLNLLDGLGFVDDIDHLGNRRLRCVGELLQNQFRIGLSRME
RVVRERMTIQDVDSITPSALINIRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRERAGFEVRDVHH
SHYGRMCPIETPEGPNIGLISSLSSYGKVNEFGFIETPYRKVDKENGLVTEKIEYLSAHEEDKYVIAQANTPLDSDGYFS
SDRITARYRHETLITTPDKIDYMDVSPRQLVSVATAQIPFLENDDANRALMGSNMQRQAVPLLQTESPLVGTGMEYRTAY
DSGAVVKSRADGTVDKVQSNEIWVRRNDNAKGRVVNGRTGEVFEGETGEVRAGYDIYKLQKFQRSNQGTCMNQVPIVEEG
QQITENQILADGPSTDNGEIALGQNVLVGFMPWEGYNYEDAILISEKLVKDDTFTSIHIEEYEAEARDAKLGPEEITRDI
PNVGEDALKNLDERGIVRIGAEVKSGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGEHGIVVDVKVF
NRDDGDELPPGVNQLVRVYIAQKRKISEGDKMAGRHGNKGVIAKILPEEDMPFLPDGTPLEIILSPLGVPSRMNLGQVLE
THLGWAAKALGLKMASPVFDGADEDEILETLKEAGLPENGKTQLVDGRTGEPFDNEVTVGYIYMLKLAHLVDDKIHARST
GPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYSLQELLTVKSDDVVGRVKTYESIVKGDNVPEPGIPESFKVLIK
ELQSLGMDVKVLNEEQGLVSIKDGEGNEEVVSVEDLNLDLKDADQDSSSQRDE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI4505941, Length=419, Percent_Identity=29.3556085918854, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI238908505, Length=410, Percent_Identity=30.9756097560976, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI238908503, Length=410, Percent_Identity=30.9756097560976, Blast_Score=165, Evalue=3e-40,
Organism=Homo sapiens, GI212286172, Length=427, Percent_Identity=27.4004683840749, Blast_Score=157, Evalue=7e-38,
Organism=Homo sapiens, GI33469941, Length=427, Percent_Identity=27.4004683840749, Blast_Score=157, Evalue=8e-38,
Organism=Escherichia coli, GI1790419, Length=674, Percent_Identity=53.2640949554896, Blast_Score=703, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=416, Percent_Identity=31.25, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17552304, Length=418, Percent_Identity=30.3827751196172, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17506623, Length=184, Percent_Identity=38.5869565217391, Blast_Score=121, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324725, Length=418, Percent_Identity=29.6650717703349, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324781, Length=411, Percent_Identity=29.1970802919708, Blast_Score=161, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6325267, Length=389, Percent_Identity=29.5629820051414, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17136444, Length=419, Percent_Identity=27.9236276849642, Blast_Score=163, Evalue=7e-40,
Organism=Drosophila melanogaster, GI17647877, Length=428, Percent_Identity=29.9065420560748, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI17136446, Length=428, Percent_Identity=28.2710280373832, Blast_Score=125, Evalue=1e-28,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 130776; Mature: 130645

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPASENLRRSYSKLDEVFELPDLIEIQKSSYQWFLDEGLKEMFDDISPIEDFTGGLVL
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCEEE
EFVDYSLGEPKYSVEDCKERDVTYSVPLKVKVRLVNQETGEVKEQEVFMGDFPLMTENGT
EEHHHCCCCCCCCHHHHHHCCCEEECCEEEEEEEECCCCCCCCHHHEEECCCCEEECCCE
FIINGAERVIVSQLVRSPGVYFSSEIDSNGNTLYSGTIIPNRGAWLEFEMNAQNVISVRV
EEECCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEEECCCEEEEEEE
DRTRKLPVTVLIRALGYGTDDDIFHLFGEDPRIKATLEKDHTDSYEAGILEIYKRLRPGE
CCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCC
PLNVENAKSLFESLFFDPKRYDLAKVGRHKINQKLELGDRLLGKTARETITDDETGEVII
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
EEGTVIDTQDLEKLEQSGITSIRIGKDDQEDRDCVVLTNGDVDKNVKNLTRNDIVASIGY
ECCCEECHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
MLNLLDGLGFVDDIDHLGNRRLRCVGELLQNQFRIGLSRMERVVRERMTIQDVDSITPSA
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHH
LINIRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRERAGFEVRDVH
HEEHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
HSHYGRMCPIETPEGPNIGLISSLSSYGKVNEFGFIETPYRKVDKENGLVTEKIEYLSAH
HHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCC
EEDKYVIAQANTPLDSDGYFSSDRITARYRHETLITTPDKIDYMDVSPRQLVSVATAQIP
CCCCEEEEECCCCCCCCCCCCCCCEEEEEECCEEEECCCCCCEECCCHHHHHHHHHHHCC
FLENDDANRALMGSNMQRQAVPLLQTESPLVGTGMEYRTAYDSGAVVKSRADGTVDKVQS
CCCCCCCCCHHHCCCCHHHCCCCEECCCCCEECCCHHEEECCCCCEEECCCCCCHHHCCC
NEIWVRRNDNAKGRVVNGRTGEVFEGETGEVRAGYDIYKLQKFQRSNQGTCMNQVPIVEE
CCEEEEECCCCCCEEECCCCCCEECCCCCCEECCCHHHHHHHHHCCCCCCCCCCCCCHHC
GQQITENQILADGPSTDNGEIALGQNVLVGFMPWEGYNYEDAILISEKLVKDDTFTSIHI
CCHHCCCCEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCEEEEHHHHHCCCCEEEEEE
EEYEAEARDAKLGPEEITRDIPNVGEDALKNLDERGIVRIGAEVKSGDILVGKVTPKGET
HHHHCHHHHCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEECCEECCCCEEEEECCCCCCC
ELTAEERLLRAIFGEKAREVRDTSLKVPHGEHGIVVDVKVFNRDDGDELPPGVNQLVRVY
CCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
IAQKRKISEGDKMAGRHGNKGVIAKILPEEDMPFLPDGTPLEIILSPLGVPSRMNLGQVL
HHHHHCCCCCCHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHEEEECCCCCCCCCHHHHH
ETHLGWAAKALGLKMASPVFDGADEDEILETLKEAGLPENGKTQLVDGRTGEPFDNEVTV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEH
GYIYMLKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYSL
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHCCHHHH
QELLTVKSDDVVGRVKTYESIVKGDNVPEPGIPESFKVLIKELQSLGMDVKVLNEEQGLV
HHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEE
SIKDGEGNEEVVSVEDLNLDLKDADQDSSSQRDE
EEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKPASENLRRSYSKLDEVFELPDLIEIQKSSYQWFLDEGLKEMFDDISPIEDFTGGLVL
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCEEE
EFVDYSLGEPKYSVEDCKERDVTYSVPLKVKVRLVNQETGEVKEQEVFMGDFPLMTENGT
EEHHHCCCCCCCCHHHHHHCCCEEECCEEEEEEEECCCCCCCCHHHEEECCCCEEECCCE
FIINGAERVIVSQLVRSPGVYFSSEIDSNGNTLYSGTIIPNRGAWLEFEMNAQNVISVRV
EEECCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEEECCCEEEEEEE
DRTRKLPVTVLIRALGYGTDDDIFHLFGEDPRIKATLEKDHTDSYEAGILEIYKRLRPGE
CCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCC
PLNVENAKSLFESLFFDPKRYDLAKVGRHKINQKLELGDRLLGKTARETITDDETGEVII
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
EEGTVIDTQDLEKLEQSGITSIRIGKDDQEDRDCVVLTNGDVDKNVKNLTRNDIVASIGY
ECCCEECHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
MLNLLDGLGFVDDIDHLGNRRLRCVGELLQNQFRIGLSRMERVVRERMTIQDVDSITPSA
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHH
LINIRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRERAGFEVRDVH
HEEHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
HSHYGRMCPIETPEGPNIGLISSLSSYGKVNEFGFIETPYRKVDKENGLVTEKIEYLSAH
HHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCC
EEDKYVIAQANTPLDSDGYFSSDRITARYRHETLITTPDKIDYMDVSPRQLVSVATAQIP
CCCCEEEEECCCCCCCCCCCCCCCEEEEEECCEEEECCCCCCEECCCHHHHHHHHHHHCC
FLENDDANRALMGSNMQRQAVPLLQTESPLVGTGMEYRTAYDSGAVVKSRADGTVDKVQS
CCCCCCCCCHHHCCCCHHHCCCCEECCCCCEECCCHHEEECCCCCEEECCCCCCHHHCCC
NEIWVRRNDNAKGRVVNGRTGEVFEGETGEVRAGYDIYKLQKFQRSNQGTCMNQVPIVEE
CCEEEEECCCCCCEEECCCCCCEECCCCCCEECCCHHHHHHHHHCCCCCCCCCCCCCHHC
GQQITENQILADGPSTDNGEIALGQNVLVGFMPWEGYNYEDAILISEKLVKDDTFTSIHI
CCHHCCCCEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCEEEEHHHHHCCCCEEEEEE
EEYEAEARDAKLGPEEITRDIPNVGEDALKNLDERGIVRIGAEVKSGDILVGKVTPKGET
HHHHCHHHHCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEECCEECCCCEEEEECCCCCCC
ELTAEERLLRAIFGEKAREVRDTSLKVPHGEHGIVVDVKVFNRDDGDELPPGVNQLVRVY
CCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
IAQKRKISEGDKMAGRHGNKGVIAKILPEEDMPFLPDGTPLEIILSPLGVPSRMNLGQVL
HHHHHCCCCCCHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHEEEECCCCCCCCCHHHHH
ETHLGWAAKALGLKMASPVFDGADEDEILETLKEAGLPENGKTQLVDGRTGEPFDNEVTV
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEH
GYIYMLKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYSL
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHCCHHHH
QELLTVKSDDVVGRVKTYESIVKGDNVPEPGIPESFKVLIKELQSLGMDVKVLNEEQGLV
HHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEE
SIKDGEGNEEVVSVEDLNLDLKDADQDSSSQRDE
EEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192928; 11058132 [H]