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The map label for this gene is pdxJ [H]

Identifier: 188528373

GI number: 188528373

Start: 1602164

End: 1602952

Strand: Direct

Name: pdxJ [H]

Synonym: HPSH_08235

Alternate gene names: 188528373

Gene position: 1602164-1602952 (Clockwise)

Preceding gene: 188528369

Following gene: 188528374

Centisome position: 99.6

GC content: 38.53

Gene sequence:

>789_bases
ATGCGTTTTGGATTGAATATTGATCACATTGTTACTTTAAGAGAGATAAGAAAAACTTATGAGCCTGAGATTTTAGAAGC
CCTATTCATCGCTAAAAACACCCATAAAGTGGATTTAATCACCATTCATTTGAGGGAAGACAAACGGCACATTCAAAACG
AAGATGTTTTGAGGCTGCTTGAAATAAGCCCTTTGCCTATCAATATTGAATGCTCTATTAATGCTGGAATCACTGATTTT
TTATGCTCTTTAAAAAATAAGCCGAGTAAGGTTACAATCGTGCCTGAAAACAGAAATGAGGTTACGACAGAGGGGGGGTT
GGATTGCTCATTAAAAGGTTTAGGAGAGGTTATTAGAGCGTATCACAATAAAGGCGTTGAAGTGTCTTTGTTTATTGATC
CTTTAAAAGACGCCCTGCATTTTGCAAGGGAGCATCAAGTCAAGCAAGTGGAGTTCCACACTGGGGTGTATGCGAATTTG
CACAACGCTCTATATTCTAACGCTAACAACCAAATCCATGCCATTAGTGCGCTCAAAGACAAAAGCCCTAAAGAATTGAA
AGAAGAATTGCACAATGCCTTTTTGCAATTAAGAAAAATGAGTAAAGAAGCGTTTTTTATGGGTATCACGGCGTGCGCGG
GGCATGGGTTGAATTATTCTAATGTGAAAGAATTGTTAAAAATCCCCTCTTTAAGAGAGCTTAATATCGGCCATAGCGTG
ATTTCAAAAGCGGTTTTAGTGGGCTTAGAAAAAGCGATTTTAGAAATGGCGCAACTCATCAAGCGATAA

Upstream 100 bases:

>100_bases
ATTATAGCAAAAGATAGCGTGATGATAAAATCTTATAGGTGTAAGAGGTGGGTTTTATGTTACAATTTCAAAAATCATTA
TTATAAAATAAAGGATAGTC

Downstream 100 bases:

>100_bases
AATGGCTAAAAAGAAAATTGCGATCAGTTGTGGGGATATTCAAGGCGTAGGCTTAGAATTGATTTTAAAAAGCCATAAGG
AAGTGAGCGCACTCTGTGAG

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLLEISPLPINIECSINAGITDF
LCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRAYHNKGVEVSLFIDPLKDALHFAREHQVKQVEFHTGVYANL
HNALYSNANNQIHAISALKDKSPKELKEELHNAFLQLRKMSKEAFFMGITACAGHGLNYSNVKELLKIPSLRELNIGHSV
ISKAVLVGLEKAILEMAQLIKR

Sequences:

>Translated_262_residues
MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLLEISPLPINIECSINAGITDF
LCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRAYHNKGVEVSLFIDPLKDALHFAREHQVKQVEFHTGVYANL
HNALYSNANNQIHAISALKDKSPKELKEELHNAFLQLRKMSKEAFFMGITACAGHGLNYSNVKELLKIPSLRELNIGHSV
ISKAVLVGLEKAILEMAQLIKR
>Mature_262_residues
MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLLEISPLPINIECSINAGITDF
LCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRAYHNKGVEVSLFIDPLKDALHFAREHQVKQVEFHTGVYANL
HNALYSNANNQIHAISALKDKSPKELKEELHNAFLQLRKMSKEAFFMGITACAGHGLNYSNVKELLKIPSLRELNIGHSV
ISKAVLVGLEKAILEMAQLIKR

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=260, Percent_Identity=36.5384615384615, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 29579; Mature: 29579

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLL
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEEECCHHHCCCHHHHHHH
EISPLPINIECSINAGITDFLCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRA
CCCCCCEEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHH
YHNKGVEVSLFIDPLKDALHFAREHQVKQVEFHTGVYANLHNALYSNANNQIHAISALKD
HHCCCCEEEEEEHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHCCCCCCEEEEHHHCC
KSPKELKEELHNAFLQLRKMSKEAFFMGITACAGHGLNYSNVKELLKIPSLRELNIGHSV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHH
ISKAVLVGLEKAILEMAQLIKR
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLL
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEEECCHHHCCCHHHHHHH
EISPLPINIECSINAGITDFLCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRA
CCCCCCEEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHH
YHNKGVEVSLFIDPLKDALHFAREHQVKQVEFHTGVYANLHNALYSNANNQIHAISALKD
HHCCCCEEEEEEHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHCCCCCCEEEEHHHCC
KSPKELKEELHNAFLQLRKMSKEAFFMGITACAGHGLNYSNVKELLKIPSLRELNIGHSV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHH
ISKAVLVGLEKAILEMAQLIKR
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA