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The map label for this gene is recG [H]

Identifier: 188528292

GI number: 188528292

Start: 1521719

End: 1523590

Strand: Reverse

Name: recG [H]

Synonym: HPSH_07820

Alternate gene names: 188528292

Gene position: 1523590-1521719 (Counterclockwise)

Preceding gene: 188528295

Following gene: 188528291

Centisome position: 94.72

GC content: 37.71

Gene sequence:

>1872_bases
TTGCAAGAAACAGATAATTTATTAAAAACATTGAATGTGAAATCGCTTTTAGAAGCCTTGCTTGTTTATACGCCCAAAGG
CTATAAAGATTTAAATCTATTAAAACATTTTGAACTGGGCTTGAGCGGCGTTTTAGAAGTGGATATTTTAGATAAAAGAA
ACTACGCCAAAGTTTTAAAGATTTTTGCCTATTCCAAACGATTTTACAAAAATTTAGAGCTTGTTTTTTTCAATTACAGC
GCGTTCCATCACAACCAGTTTAAAACCGGCGAGAGTTTGTTCATTTATGGTAAATTAGAGCAAAGCTCTTTTAATCAAGC
TTATATCATTAACACGCCTAAAATCCTTACCGAATTTGGCAAAATTTCTTTAATTTTTAAAAAAGTTAAAAATCATAAAA
AAATACAAGAAAATTTACAAAAACTCATTTCATTAGAGAATTTAAAAAAGGAAGGCATTAAAGAGAATATCGCGCATTTA
TTGTTAGAAATCTTTTTCCCCACGCCGCATTTTGTCAAGGATTTTGAAACTCATAAAAATTTTTCTTCACAACATTTAAA
CGCATTAAAATACATTGAAATGCTTTTTTATATGAAAAATTTAGAGCGCAAAAAATTGCAATTCAATGCTAAAATCGCAT
GCCCCAATAACAGCGAGCGCTTTAAAGCGTTTATTGCTTCTTTACCCTTTCAACTCACCAACGACCAACAAAACGCCATT
AAAGAAATCCAAAGCGATCTTGCTAGCCCTATAGCGTGCAAGCGTTTGATTATAGGCGATGTGGGGTGCGGGAAAACGAT
GGTGATTTTAGCGAGCATGGTATTAGCTTACCCTAATAAAACCCTTTTAATGGCGCCCACTTCCATTCTCGCTAAACAGC
TTTATAACGAAGCCTTAAAATTTTTACCCCCTTATTTTGAAGTGGAATTATTGCTTGGCGGGAGCCACAAGAAGCGATCC
AATCATTTGTTTGAAACAATCACGCATGTGGTTATAGGCACGCAAGCGTTGTTGTTTGATAAGCGCGATTTGAATGAATT
CGCTCTAGTGATCACTGATGAGCAGCACCGGTTCGGCACAAAGCAGCGCTACCAATTAGAAAAAATGGCAAGCAGTAAGG
GTCATAAACCCCATTCCTTGCAATTTTCCGCTACCCCCATTCCTCGCACGCTTGCCCTAGCCAAAAGCGCGTTTGTGAAA
ACGACCATGATTAGAGAAATCCCTTACCCTAAAGAGATTGAAACTTTAGTCTTGCATAAAAGAGATTTTAAAATAGTGAT
GGAAAAAATCAGCGAAGAAATCGCTAAAAACCATCAAGTCATTGTCGTCTATCCGCTGGTGAATGAGAGCGAAAAAATCC
CGTATTTATCGCTCAGTGAGGGGGCAAGTTTTTGGCAAAAACGCTTTAAAAAGGTTTATACCACTTCAGGGCAAGATAAA
AATAAAGAAGAAGTGATTGAAGAATTTAGAGAGTCCGGGAGCATTCTTTTAGCGACTACGCTCATTGAGGTGGGCATTTC
TTTACCACGATTGAGCGTGATGGTGATTTTAGCGCCTGAAAGGTTAGGCTTAGCGACTTTACACCAGTTAAGGGGGCGCG
TTTCTCGTAACGGATTGAAAGGCTATTGTTTTTTATGCACGATCCAAGAAGAAAACGAACGATTAGAAAAATTTGCTGAC
GAATTAGACGGCTTTAAAATCGCTGAATTGGATTTAGAATACAGAAAAAGCGGGGACTTGCTCCAGGGTGGGGAGCAGAG
CGGGAATAGTTTTGAATACATTGACTTAGCCAAAGATGAAAACATTATCGCTGAAGTGAAACGGGACTTTTTAAAAACCG
CTAGCGTTTCACGGGGAACATTTGAAAATTAA

Upstream 100 bases:

>100_bases
GAGTGATTTTAGATTTCATCAATTAAATTTCCTTAAGTCAATGTATAATTTGATTATCTTATCATAAAAATGATTAAGGA
TTGGCTAGGGTAAGAACAAA

Downstream 100 bases:

>100_bases
GGTGGAATTGGGTAATTTAAATCATTTAAAAAAAGGATAGAGATGCAAAATAAAGAAATTTATGGAGAAAAAAGCGTTAA
GGAAAAAAATTTAGAGGTAT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MQETDNLLKTLNVKSLLEALLVYTPKGYKDLNLLKHFELGLSGVLEVDILDKRNYAKVLKIFAYSKRFYKNLELVFFNYS
AFHHNQFKTGESLFIYGKLEQSSFNQAYIINTPKILTEFGKISLIFKKVKNHKKIQENLQKLISLENLKKEGIKENIAHL
LLEIFFPTPHFVKDFETHKNFSSQHLNALKYIEMLFYMKNLERKKLQFNAKIACPNNSERFKAFIASLPFQLTNDQQNAI
KEIQSDLASPIACKRLIIGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALKFLPPYFEVELLLGGSHKKRS
NHLFETITHVVIGTQALLFDKRDLNEFALVITDEQHRFGTKQRYQLEKMASSKGHKPHSLQFSATPIPRTLALAKSAFVK
TTMIREIPYPKEIETLVLHKRDFKIVMEKISEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKKVYTTSGQDK
NKEEVIEEFRESGSILLATTLIEVGISLPRLSVMVILAPERLGLATLHQLRGRVSRNGLKGYCFLCTIQEENERLEKFAD
ELDGFKIAELDLEYRKSGDLLQGGEQSGNSFEYIDLAKDENIIAEVKRDFLKTASVSRGTFEN

Sequences:

>Translated_623_residues
MQETDNLLKTLNVKSLLEALLVYTPKGYKDLNLLKHFELGLSGVLEVDILDKRNYAKVLKIFAYSKRFYKNLELVFFNYS
AFHHNQFKTGESLFIYGKLEQSSFNQAYIINTPKILTEFGKISLIFKKVKNHKKIQENLQKLISLENLKKEGIKENIAHL
LLEIFFPTPHFVKDFETHKNFSSQHLNALKYIEMLFYMKNLERKKLQFNAKIACPNNSERFKAFIASLPFQLTNDQQNAI
KEIQSDLASPIACKRLIIGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALKFLPPYFEVELLLGGSHKKRS
NHLFETITHVVIGTQALLFDKRDLNEFALVITDEQHRFGTKQRYQLEKMASSKGHKPHSLQFSATPIPRTLALAKSAFVK
TTMIREIPYPKEIETLVLHKRDFKIVMEKISEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKKVYTTSGQDK
NKEEVIEEFRESGSILLATTLIEVGISLPRLSVMVILAPERLGLATLHQLRGRVSRNGLKGYCFLCTIQEENERLEKFAD
ELDGFKIAELDLEYRKSGDLLQGGEQSGNSFEYIDLAKDENIIAEVKRDFLKTASVSRGTFEN
>Mature_623_residues
MQETDNLLKTLNVKSLLEALLVYTPKGYKDLNLLKHFELGLSGVLEVDILDKRNYAKVLKIFAYSKRFYKNLELVFFNYS
AFHHNQFKTGESLFIYGKLEQSSFNQAYIINTPKILTEFGKISLIFKKVKNHKKIQENLQKLISLENLKKEGIKENIAHL
LLEIFFPTPHFVKDFETHKNFSSQHLNALKYIEMLFYMKNLERKKLQFNAKIACPNNSERFKAFIASLPFQLTNDQQNAI
KEIQSDLASPIACKRLIIGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALKFLPPYFEVELLLGGSHKKRS
NHLFETITHVVIGTQALLFDKRDLNEFALVITDEQHRFGTKQRYQLEKMASSKGHKPHSLQFSATPIPRTLALAKSAFVK
TTMIREIPYPKEIETLVLHKRDFKIVMEKISEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKKVYTTSGQDK
NKEEVIEEFRESGSILLATTLIEVGISLPRLSVMVILAPERLGLATLHQLRGRVSRNGLKGYCFLCTIQEENERLEKFAD
ELDGFKIAELDLEYRKSGDLLQGGEQSGNSFEYIDLAKDENIIAEVKRDFLKTASVSRGTFEN

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=583, Percent_Identity=31.5608919382504, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1787357, Length=393, Percent_Identity=32.3155216284987, Blast_Score=173, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 71457; Mature: 71457

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQETDNLLKTLNVKSLLEALLVYTPKGYKDLNLLKHFELGLSGVLEVDILDKRNYAKVLK
CCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHH
IFAYSKRFYKNLELVFFNYSAFHHNQFKTGESLFIYGKLEQSSFNQAYIINTPKILTEFG
HHHHHHHHHCCEEEEEEEEEHEECCCCCCCCEEEEEEEECCCCCCCEEEEECHHHHHHHH
KISLIFKKVKNHKKIQENLQKLISLENLKKEGIKENIAHLLLEIFFPTPHFVKDFETHKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
FSSQHLNALKYIEMLFYMKNLERKKLQFNAKIACPNNSERFKAFIASLPFQLTNDQQNAI
CCHHHHHHHHHHHHHHHHHCCHHHHEEEEEEEECCCCHHHHHHHHHHCCCEECCCHHHHH
KEIQSDLASPIACKRLIIGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALK
HHHHHHHCCHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHH
FLPPYFEVELLLGGSHKKRSNHLFETITHVVIGTQALLFDKRDLNEFALVITDEQHRFGT
HCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHEEECCCCCCCEEEEEECCHHHCCC
KQRYQLEKMASSKGHKPHSLQFSATPIPRTLALAKSAFVKTTMIREIPYPKEIETLVLHK
HHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RDFKIVMEKISEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKKVYTTSGQDK
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCC
NKEEVIEEFRESGSILLATTLIEVGISLPRLSVMVILAPERLGLATLHQLRGRVSRNGLK
CHHHHHHHHHHCCCEEEEHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCC
GYCFLCTIQEENERLEKFADELDGFKIAELDLEYRKSGDLLQGGEQSGNSFEYIDLAKDE
EEEEEEEEECHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCCCCCCCCEEEEEECCCC
NIIAEVKRDFLKTASVSRGTFEN
HHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQETDNLLKTLNVKSLLEALLVYTPKGYKDLNLLKHFELGLSGVLEVDILDKRNYAKVLK
CCCHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHH
IFAYSKRFYKNLELVFFNYSAFHHNQFKTGESLFIYGKLEQSSFNQAYIINTPKILTEFG
HHHHHHHHHCCEEEEEEEEEHEECCCCCCCCEEEEEEEECCCCCCCEEEEECHHHHHHHH
KISLIFKKVKNHKKIQENLQKLISLENLKKEGIKENIAHLLLEIFFPTPHFVKDFETHKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
FSSQHLNALKYIEMLFYMKNLERKKLQFNAKIACPNNSERFKAFIASLPFQLTNDQQNAI
CCHHHHHHHHHHHHHHHHHCCHHHHEEEEEEEECCCCHHHHHHHHHHCCCEECCCHHHHH
KEIQSDLASPIACKRLIIGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALK
HHHHHHHCCHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHH
FLPPYFEVELLLGGSHKKRSNHLFETITHVVIGTQALLFDKRDLNEFALVITDEQHRFGT
HCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHEEECCCCCCCEEEEEECCHHHCCC
KQRYQLEKMASSKGHKPHSLQFSATPIPRTLALAKSAFVKTTMIREIPYPKEIETLVLHK
HHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RDFKIVMEKISEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKKVYTTSGQDK
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCC
NKEEVIEEFRESGSILLATTLIEVGISLPRLSVMVILAPERLGLATLHQLRGRVSRNGLK
CHHHHHHHHHHCCCEEEEHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCC
GYCFLCTIQEENERLEKFADELDGFKIAELDLEYRKSGDLLQGGEQSGNSFEYIDLAKDE
EEEEEEEEECHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCCCCCCCCEEEEEECCCC
NIIAEVKRDFLKTASVSRGTFEN
HHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]