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The map label for this gene is trxA [H]

Identifier: 188528229

GI number: 188528229

Start: 1447292

End: 1447606

Strand: Reverse

Name: trxA [H]

Synonym: HPSH_07465

Alternate gene names: 188528229

Gene position: 1447606-1447292 (Counterclockwise)

Preceding gene: 188528230

Following gene: 188528228

Centisome position: 89.99

GC content: 41.27

Gene sequence:

>315_bases
ATGTCAGAAATTATTAACGGGAAGAATTACGCAGAGAAAATCGCTCATCAAGCGGTAGTGGTTAATGTCGGGGCGAGCTG
GTGCCCAGATTGCAGGAAGATTGAGCCGATTATGGAAAATTTAGCCAAAACTTACAAAGACAAGGTGGAATTTTTTAAGG
TTTCTTTTGATGAGAGCCAGGATTTAAAAGAGAGCTTAGGTATTCGCAAGATCCCCACTTTGATTTTTTACAAAAACGGG
AAAGAAGTGGGTGAAAGGCTTGTAGAGCCCGGATCTTCAAAGCCGATTGAAGACGCGATTAAAACGCTCTTATAA

Upstream 100 bases:

>100_bases
GTTGCATGCGTTTATGGCTAATGCGGCTAATGTTAAAGAGGATTAACTTACGAGTTATGCTATACTTTGGGGTTGGGGGA
AATAAAAAATAAGGATTATC

Downstream 100 bases:

>100_bases
AGAGCGTTAAAGAGCCTTGTTTTAAAAAGAACCCATAGGAATCTTTTTTAGCCCCTTTTTTGATAAAGGGGCTAACTTCA
AATAGTTTTTATCTTTCTTT

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MSEIINGKNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKDKVEFFKVSFDESQDLKESLGIRKIPTLIFYKNG
KEVGERLVEPGSSKPIEDAIKTLL

Sequences:

>Translated_104_residues
MSEIINGKNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKDKVEFFKVSFDESQDLKESLGIRKIPTLIFYKNG
KEVGERLVEPGSSKPIEDAIKTLL
>Mature_103_residues
SEIINGKNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKDKVEFFKVSFDESQDLKESLGIRKIPTLIFYKNGK
EVGERLVEPGSSKPIEDAIKTLL

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788936, Length=65, Percent_Identity=41.5384615384615, Blast_Score=61, Evalue=1e-11,
Organism=Escherichia coli, GI87082331, Length=67, Percent_Identity=37.3134328358209, Blast_Score=59, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321648, Length=65, Percent_Identity=44.6153846153846, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 11730; Mature: 11598

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIINGKNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKDKVEFFKVSFDESQ
CCCCCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DLKESLGIRKIPTLIFYKNGKEVGERLVEPGSSKPIEDAIKTLL
HHHHHCCCCCCCHHEEECCCHHHHHHHHCCCCCCCHHHHHHHHC
>Mature Secondary Structure 
SEIINGKNYAEKIAHQAVVVNVGASWCPDCRKIEPIMENLAKTYKDKVEFFKVSFDESQ
CCCCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DLKESLGIRKIPTLIFYKNGKEVGERLVEPGSSKPIEDAIKTLL
HHHHHCCCCCCCHHEEECCCHHHHHHHHCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA