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The map label for this gene is rnpA [H]

Identifier: 188528218

GI number: 188528218

Start: 1436920

End: 1437405

Strand: Direct

Name: rnpA [H]

Synonym: HPSH_07410

Alternate gene names: 188528218

Gene position: 1436920-1437405 (Clockwise)

Preceding gene: 188528217

Following gene: 188528219

Centisome position: 89.33

GC content: 37.45

Gene sequence:

>486_bases
ATGCCAGACGAGCTAAGGGCAGAAAAAAGCTTTCCGTCTAAACCCTATGACTCTTTAAAAAACAAGAGTGAGTTTGATAG
GGTTTATCAAAAGGGCTTCAAAAAACACAACCCTTTTTTTTCGCTCTTTGTTTTGGATTTATCAAAAGAGCCACCAAAAG
AAAAAGAGGGCTTTAAAGATCCGCTCTCTTGTAGGCTTAAAGACAAAAAAACGCTTTATTTATTAGGTTTGAGCGTGTCC
AAAAAAGTCGGCAACGCCGTGAAACGAAACCTTATCAAACGCCGTTTGCGTTCGCTCACATTAAAGCATGCTGCGCTTTG
TCAAGGGCTTGCTTTGGTGTTTGTGCCTAGAAGCGATTGTTACCATTTAGATTTTTGGGCTTTAGAAAAACATTTTTTAG
AAATGCTAACTTCCATTAAAAACTATATGAACAAAGCCTTAAAAGGCTTGAAAAAAGGAATAACTCATACCTATGCGAAA
CAATAA

Upstream 100 bases:

>100_bases
TTTTAAATGAAACGCACTTACCAACCACACAACACACCAAGAAAGCGAACCCATGGCTTTCTTGTGAGGATGAAAACCAA
AAACGGGCGCAAGGTGATTA

Downstream 100 bases:

>100_bases
AACGCCTTTTTTGAGCGCGATTTTTACGGCATTGATTAGGGGTTACCAACGCTTTTTTTCGGCTTTCACCTTTTCAAGCT
GTCGGTTTTACCCCACTTGC

Product: ribonuclease P, protein component (rnpA)

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5 [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MPDELRAEKSFPSKPYDSLKNKSEFDRVYQKGFKKHNPFFSLFVLDLSKEPPKEKEGFKDPLSCRLKDKKTLYLLGLSVS
KKVGNAVKRNLIKRRLRSLTLKHAALCQGLALVFVPRSDCYHLDFWALEKHFLEMLTSIKNYMNKALKGLKKGITHTYAK
Q

Sequences:

>Translated_161_residues
MPDELRAEKSFPSKPYDSLKNKSEFDRVYQKGFKKHNPFFSLFVLDLSKEPPKEKEGFKDPLSCRLKDKKTLYLLGLSVS
KKVGNAVKRNLIKRRLRSLTLKHAALCQGLALVFVPRSDCYHLDFWALEKHFLEMLTSIKNYMNKALKGLKKGITHTYAK
Q
>Mature_160_residues
PDELRAEKSFPSKPYDSLKNKSEFDRVYQKGFKKHNPFFSLFVLDLSKEPPKEKEGFKDPLSCRLKDKKTLYLLGLSVSK
KVGNAVKRNLIKRRLRSLTLKHAALCQGLALVFVPRSDCYHLDFWALEKHFLEMLTSIKNYMNKALKGLKKGITHTYAKQ

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- ProDom:   PD003629 [H]

Pfam domain/function: PF00825 Ribonuclease_P [H]

EC number: =3.1.26.5 [H]

Molecular weight: Translated: 18693; Mature: 18562

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDELRAEKSFPSKPYDSLKNKSEFDRVYQKGFKKHNPFFSLFVLDLSKEPPKEKEGFKD
CCCHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCC
PLSCRLKDKKTLYLLGLSVSKKVGNAVKRNLIKRRLRSLTLKHAALCQGLALVFVPRSDC
CHHEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCC
YHLDFWALEKHFLEMLTSIKNYMNKALKGLKKGITHTYAKQ
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDELRAEKSFPSKPYDSLKNKSEFDRVYQKGFKKHNPFFSLFVLDLSKEPPKEKEGFKD
CCHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCC
PLSCRLKDKKTLYLLGLSVSKKVGNAVKRNLIKRRLRSLTLKHAALCQGLALVFVPRSDC
CHHEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCC
YHLDFWALEKHFLEMLTSIKNYMNKALKGLKKGITHTYAKQ
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA