Click here to switch to the map view.

The map label for this gene is phoR [H]

Identifier: 188528153

GI number: 188528153

Start: 1370680

End: 1371813

Strand: Reverse

Name: phoR [H]

Synonym: HPSH_07060

Alternate gene names: 188528153

Gene position: 1371813-1370680 (Counterclockwise)

Preceding gene: 188528154

Following gene: 188528152

Centisome position: 85.28

GC content: 38.01

Gene sequence:

>1134_bases
TTGGGCTCTTCGTTTGTGTTGATGCTAGTGATTAGCGTTTTAGCGTTTAACTATGAAAAAAACGAAAAAATCAAAATGAT
ACGCATGGACATGGACAAAATGGCTTCCAAGATCGCTAGTGAAGTGGTTGCTTTGCACATGCAAACGCATGGGGATTATC
AAAACGCTTTAAACGCTCTGATTTCACGCTATAAAGACGCTTCCATAGCCCTTTTTGATAGCAAAAGGCGTGTTTTGTAT
TCTAATATCCCTGAAAGCGCAAATTTGATTAAAAACCATAAAGAAGCGGGCTTTTTTAGTTTTAGGGGAGAGTATTACCT
GTTTAGCGATGAAACTTTCGCTCACTTAGGCGTGGCTAAAATGCTTTTTAAAAATTCTAAACCCCTTCATTTTTCTTCTT
TGTATCGTAACATTGTTTTAGTGTTTGTCATAGCGTTTTCATGCGTGATAGGGGTTTCTGTGTTTTTGGGGCGTTTGTTT
TTAAAGCCCATTAGGAATGAAATCACCCGTATTGATCATTTTTTAAAAAACACCACGCATGAATTAAACACCCCCATGAG
CGCTTTAGTCTTGTCTTTAAAAACCTTAGAAGACAACCAACAGCACCGCCGCATTAAAATCGCCATCCAGCGCATGAGTT
TTTTATACCGCTCGCTCTCGTATTTAGTGATGCAAGATATTGAGTGCGAATCCCCCATGCTTTTAGATTTAAAAGCCCTA
ATTACCAAAGAAAACACGCTTTTTAGCGAGATGATAGACTACCACAAGCTGGAATTTAAAAGCGATTTAGTGGGAGTGGA
GATTAAGGCTAAAGAGCAGGATTTCATTTCGCTTTATAGCAATTTGCTCATGAATGCGATCAAATACAGCGTCATGCATG
GGTATATCCACATAGAGCTAACGCATGCGTTTTTGAAAGTGAAGAATTTAGGGTATGAAATCCCTAAAGACAAGATCGCA
GAATTAAGCGTTCGTTATGCGCGTTTCAATTCTAGCGTGTTGGGTTATGGTATAGGGTTAGATTTAGTGAAAAAAGTGTG
TGAAAAGTATAAAATGCGTTTAGAAATTCATAGCGAACCCTCTTTAAAAGGATCGTTTTATGAAAATTCGTTTTGCGTTC
AATTTCAAGGATAA

Upstream 100 bases:

>100_bases
AAGCTTTTAGGTAAAAATTGCATAGAAACGCATAAGGGGGTGGGCTATCGCTTTAACCCACTATGAAAAAAAATCCCTTA
AACTCTTTTTAGGGACTTAT

Downstream 100 bases:

>100_bases
AGATGCTTTCAGTGTATGAAAAAGTGAATGCTCTAGACAAAAGGGCGCTTGAAAAATTTAATTTAAGCGAAGACATTTTA
ATGGAAAACGCCGCTATGGC

Product: signal-transducing protein, histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MGSSFVLMLVISVLAFNYEKNEKIKMIRMDMDKMASKIASEVVALHMQTHGDYQNALNALISRYKDASIALFDSKRRVLY
SNIPESANLIKNHKEAGFFSFRGEYYLFSDETFAHLGVAKMLFKNSKPLHFSSLYRNIVLVFVIAFSCVIGVSVFLGRLF
LKPIRNEITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQQHRRIKIAIQRMSFLYRSLSYLVMQDIECESPMLLDLKAL
ITKENTLFSEMIDYHKLEFKSDLVGVEIKAKEQDFISLYSNLLMNAIKYSVMHGYIHIELTHAFLKVKNLGYEIPKDKIA
ELSVRYARFNSSVLGYGIGLDLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCVQFQG

Sequences:

>Translated_377_residues
MGSSFVLMLVISVLAFNYEKNEKIKMIRMDMDKMASKIASEVVALHMQTHGDYQNALNALISRYKDASIALFDSKRRVLY
SNIPESANLIKNHKEAGFFSFRGEYYLFSDETFAHLGVAKMLFKNSKPLHFSSLYRNIVLVFVIAFSCVIGVSVFLGRLF
LKPIRNEITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQQHRRIKIAIQRMSFLYRSLSYLVMQDIECESPMLLDLKAL
ITKENTLFSEMIDYHKLEFKSDLVGVEIKAKEQDFISLYSNLLMNAIKYSVMHGYIHIELTHAFLKVKNLGYEIPKDKIA
ELSVRYARFNSSVLGYGIGLDLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCVQFQG
>Mature_376_residues
GSSFVLMLVISVLAFNYEKNEKIKMIRMDMDKMASKIASEVVALHMQTHGDYQNALNALISRYKDASIALFDSKRRVLYS
NIPESANLIKNHKEAGFFSFRGEYYLFSDETFAHLGVAKMLFKNSKPLHFSSLYRNIVLVFVIAFSCVIGVSVFLGRLFL
KPIRNEITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQQHRRIKIAIQRMSFLYRSLSYLVMQDIECESPMLLDLKALI
TKENTLFSEMIDYHKLEFKSDLVGVEIKAKEQDFISLYSNLLMNAIKYSVMHGYIHIELTHAFLKVKNLGYEIPKDKIAE
LSVRYARFNSSVLGYGIGLDLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCVQFQG

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43483; Mature: 43351

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSFVLMLVISVLAFNYEKNEKIKMIRMDMDKMASKIASEVVALHMQTHGDYQNALNAL
CCCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ISRYKDASIALFDSKRRVLYSNIPESANLIKNHKEAGFFSFRGEYYLFSDETFAHLGVAK
HHHCCCCEEEEECCCCHHHCCCCCCHHHHHHCCCCCCEEEECCCEEEECCCCHHHHHHHH
MLFKNSKPLHFSSLYRNIVLVFVIAFSCVIGVSVFLGRLFLKPIRNEITRIDHFLKNTTH
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ELNTPMSALVLSLKTLEDNQQHRRIKIAIQRMSFLYRSLSYLVMQDIECESPMLLDLKAL
HHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ITKENTLFSEMIDYHKLEFKSDLVGVEIKAKEQDFISLYSNLLMNAIKYSVMHGYIHIEL
HHCCHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCEEEEEE
THAFLKVKNLGYEIPKDKIAELSVRYARFNSSVLGYGIGLDLVKKVCEKYKMRLEIHSEP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHHHHEEEECCCC
SLKGSFYENSFCVQFQG
CCCCCEECCCEEEEECC
>Mature Secondary Structure 
GSSFVLMLVISVLAFNYEKNEKIKMIRMDMDKMASKIASEVVALHMQTHGDYQNALNAL
CCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ISRYKDASIALFDSKRRVLYSNIPESANLIKNHKEAGFFSFRGEYYLFSDETFAHLGVAK
HHHCCCCEEEEECCCCHHHCCCCCCHHHHHHCCCCCCEEEECCCEEEECCCCHHHHHHHH
MLFKNSKPLHFSSLYRNIVLVFVIAFSCVIGVSVFLGRLFLKPIRNEITRIDHFLKNTTH
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ELNTPMSALVLSLKTLEDNQQHRRIKIAIQRMSFLYRSLSYLVMQDIECESPMLLDLKAL
HHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ITKENTLFSEMIDYHKLEFKSDLVGVEIKAKEQDFISLYSNLLMNAIKYSVMHGYIHIEL
HHCCHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCEEEEEE
THAFLKVKNLGYEIPKDKIAELSVRYARFNSSVLGYGIGLDLVKKVCEKYKMRLEIHSEP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHHHHEEEECCCC
SLKGSFYENSFCVQFQG
CCCCCEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043; 2115874 [H]